Food Intake Patterns Research Articles

Feeding pattern, biochemical, anthropometric and histological effects of prolonged ad libitum access to sucrose, honey and glucose-fructose solutions in Wistar rats.

BACKGROUND/OBJECTIVESThe exposure to sucrose in rats has mimic abnormalities attributed to metabolic syndrome (MetS). The effects of honey bee and “free” glucose and fructose, have not been explored in this context. The aim was to expose Wistar rodents to sucrose solution (SS), honey solution (HS) and fructose/glucose solution (GFS) at 30% to assess their effects.SUBJECTS/METHODSHS (n = 10), SS (n = 10) and GFS (n = 10) groups were formed. Solutions were ad libitum along 14-weeks.RESULTSBetween solutions consumptions, honey was significantly 42% higher (P = 0.000), while similar consumption was observed among GFS and SS. The feeding pattern of HS consumption was irregular along experiment; while the food intake pattern showed the similar trend among groups along time. Non statistical differences were obtained in any biochemical and anthropometric measure, however, a higher concentration of leptin (721 ± 507 pg/mL), lower concentration of total cholesterol (TC; 48.87 ± 2.41 mg/100 mL), very low density lipoprotein (VLDL; 16.47 ± 6.55 mg/100 mL) and triglycerides (82.37 ± 32.77 mg/100 mL) was obtained in SS group. For anthropometric values, HS showed less total adipose tissue (AT; average 26 vs. 31–33 g) and adiposity index (average 6.11 vs. 7.6). Due to sugar-sweetened beverages consumption increases the risk for the development of chronic diseases; correlations between fluid intake and anthropometric and biochemical parameters were assessed. A moderate correlation was obtained in groups with the weight of total AT and solution intake; for the weight gain in GFS group and for triglycerides in HS and GFS. The highest hepatic tissue damage was observed in SS group with multiple intracytoplasmic vacuoles, atypia changes, moderate pleomorphism and hepatocellular necrosis.CONCLUSIONSIn spite of the significantly higher consumption of HS, biochemical, anthropometrical and histological effects were not remarkably different in comparision to other sweeteners.

Tympanic Membrane Rupture During Stereotaxic Surgery Disturbs the Normal Feeding Behavior in Rats.

Stereotactic surgery is a widely used procedure in neuroscience research to study the brain’s regulation of feeding behavior. In line with this notion, this study aims to assess how food consumption and feeding patterns are affected in response to the use of auditory bars that preserve or damage the tympanic membrane during stereotactic surgery. Our previous observations led us to hypothesize that the traumatic tympanic membrane rupture affects food intake and feeding patterns in rats undergoing stereotactic procedures. Thereby, female and male rats were cannulated in the third ventricle (3V) using both types of auditory bars. Post-surgical pain was assessed using the grimace scale. Food intake, meal patterns and weight gain or loss were analyzed for 5–7 consecutive days after surgery. Normal food intake, increased body weight and regular meal patterns were observed from postoperative day 2 when the stereotactic procedure was performed using auditory bars that maintain the integrity of the tympanic membrane. However, tympanic membrane rupture prevented the expected recovery of food intake and body weight. This effect was accompanied by an alteration in eating patterns, which was persistent over 7 days of recovery. Thus, tympanic membrane preservation during surgery is necessary to evaluate short-term feeding patterns. This study demonstrates auditory bars that do not damage the tympanic membrane should be used when performing stereotactic surgery for subsequent analysis of rat behavior.

Associations between nutrient intakes and dietary patterns with different sarcopenia definitions in older Australian men: the concord health and ageing in men project - ERRATUM.

Objective To assess the associations between nutrient intake and dietary patterns with different sarcopenia definitions in older men. Design Cross-sectional study. Setting Sarcopenia was defined using the Foundation for the National Institutes of Health (FNIH), the European Working Group on Sarcopenia in Older People (EWGSOP) and the European Working Group on Sarcopenia in Older People 2 (EWGSOP2). Dietary adequacy of fourteen nutrients was assessed by comparing participants' intakes with the Nutrient Reference Values (NRV). Attainment of NRV for nutrients was incorporated into a variable 'poor' (meeting ≤ 9) v. 'good' (meeting ≥ 10) using the cut-point method. Also, two different dietary patterns, monounsaturated:saturated fat and n-6:n-3 fatty acids ratio and individual nutrients were used as predictor variables. Participants A total of 794 men aged ≥75 years participated in this study. Results The prevalence of sarcopenia by the FNIH, EWGSOP and EWGSOP2 definitions was 12·9 %, 12·9 % and 19·6 %, respectively. With the adjustment, poor nutrient intake was significantly associated with FNIH-defined sarcopenia (OR: 2·07 (95 % CI 1·16, 3·67)), but not with EWGSOP and EWGSPOP2 definitions. The lowest and second-lowest quartiles of protein, Mg and Ca and the lowest quartiles of n-6 PUFA and n-3 PUFA intakes were significantly associated with FNIH-defined sarcopenia. Each unit decrease in n-6:n-3 ratio was significantly associated with a 9 % increased risk of FNIH-defined sarcopenia (OR: 1·09 (95 % CI 1·04, 1·16)). Conclusions Inadequate intakes of nutrients are associated with FNIH-defined sarcopenia in older men, but not with the other two sarcopenia definitions. Further studies are required to understand these relationships.

The Effect of Food Intake on the Incidence of Malnutrition in Toddlers in the Work Area of the Kertosari Health Center, Banyuwangi Regency

This study aims to determine the effect of food intake patterns on malnutrition incidence in toddlers in the working area of Kertosari Health Care. This study used a cross-sectional method with a research population of 30 toddlers. The data were obtained from validated questionnaires and food intake measurements using a 24 hours food recall form. Samples in this study as many as 30 malnourished toddlers and spread in the Kertosari Health Care working area. The data were analyzed using descriptive analysis techniques and ordinal logistic regression influence tests. The results of the study showed that energy intake patterns (p = 0.032), protein intake patterns (p = 0.026), fat intake patterns (p = 0.026), carbohydrate intake patterns (p = 0.014), zinc intake patterns (p = 0.043) and calcium intake patterns (p = 0.026) with the incidence of malnutrition in toddlers

Nutrient intake and dietary pattern among pregnant women visiting the tertiary level hospital of Nepal

Background: Pregnancy demands adequate nutritional requirements for foetal growth, good health of pregnant women and to avoid adverse effects during pregnancy. Women from developing countries with limited resources have inadequate consumption of nutritional diets. This paper assesses the nutrient intake and dietary pattern of Nepalese pregnant women compared with recommended nutrient intake. This paper also observes trimester wise nutrient intake among pregnant women in Nepal.Methodology: A descriptive cross-sectional study was conducted among 323 pregnant women who visited Gynaecology and Obstetrics Out-Patient Department (OPD) at Tribhuvan University Teaching Hospital (TUTH) for regular Antenatal Care (ANC) check-ups. Systematic random sampling methods were followed and data were collected from September 2016 to October 2016. Nutrient intake was evaluated with a 24-hour dietary recall method and compared with the Nepalese Food Composition Table 2017 for available nutrients. Face-to-face structured interviews were conducted to assess the nutrient intake of the respondents. The data were entered in Microsoft Excel 2007 and statistical analysis was carried out in SPSS v26. The descriptive analysis was done to identify the distribution of socio-demographic variables of pregnant women. The one-way Analysis of Variance (ANOVA) was used to compare the mean of nutrient intake distribution while Tukey’s post-hoc test was done to compare trimester-wise nutrient intakes.Results: Except for fat, the intake of nutrients were below the Nepalese Recommended Nutrient Intake. Carbohydrate and energy intake in the second and third trimester was significantly different from that in the first trimester (p = 0.006 and 0.004 respectively for carbohydrates and p = 0.009 and 0.002 respectively for energy intake). However, riboflavin intake was significantly lower only in the third trimester as compared to the first (p = 0.025) while there were no significant intake differences between the first and second trimester and second and third trimester. No significant trimester wise differences were observed for intake distribution of other nutrients. Cereal intake was found to be abundant in the diet of pregnant women followed by pulses, legumes, and other vegetables.Conclusion: The research concludes inadequate nutrient intake among pregnant women as compared to the national Recommended Nutrient Intake.

Natural food intake patterns have little synchronizing effect on peripheral circadian clocks

BackgroundCircadian rhythms across mammalian tissues are coordinated by a master clock in the suprachiasmatic nucleus (SCN) that is principally entrained by light-dark cycles. Prior investigations have shown, however, that time-restricted feeding (TRF)—daily alternation of fasting and food availability—synchronizes peripheral clocks independent of the light-dark cycle and of the SCN. This has led to the idea that downstream peripheral clocks are entrained indirectly by food intake rhythms. However, TRF is not a normal eating pattern, and it imposes non-physiologic long fasts that rodents do not typically experience. Therefore, we tested whether normal feeding patterns can phase-shift or entrain peripheral tissues by measuring circadian rhythms of the liver, kidney, and submandibular gland in mPer2Luc mice under different food schedules.ResultsWe employed home cage feeders to first measure ad libitum food intake and then to dispense 20-mg pellets on a schedule mimicking that pattern. In both conditions, PER2::LUC bioluminescence peaked during the night as expected. Surprisingly, shifting the scheduled feeding by 12 h advanced peripheral clocks by only 0–3 h, much less than predicted from TRF protocols. To isolate the effects of feeding from the light-dark cycle, clock phase was then measured in mice acclimated to scheduled feeding over the course of 3 months in constant darkness. In these conditions, peripheral clock phases were better predicted by the rest-activity cycle than by the food schedule, contrary to expectation based on TRF studies. At the end of both experiments, mice were exposed to a modified TRF with food provided in eight equally sized meals over 12 h. In the light-dark cycle, this advanced the phase of the liver and kidney, though less so than in TRF with ad libitum access; in darkness, this entrained the liver and kidney but had little effect on the submandibular gland or the rest-activity cycle.ConclusionsThese data suggest that natural feeding patterns can only weakly affect circadian clocks. Instead, in normally feeding mice, the central pacemaker in the brain may set the phase of peripheral organs via pathways that are independent of feeding behavior.

The Circadian Clock, Shift Work, and Tissue-Specific Insulin Resistance.

Obesity and type 2 diabetes (T2D) have become a global health concern. The prevalence of obesity and T2D is significantly higher in shift workers compared to people working regular hours. An accepted hypothesis is that the increased risk for metabolic health problems arises from aberrantly timed eating behavior, that is, eating out of synchrony with the biological clock. The biological clock is part of the internal circadian timing system, which controls not only the sleep/wake and feeding/fasting cycle, but also many metabolic processes in the body, including the timing of our eating behavior, and processes involved in glucose homeostasis. Rodent studies have shown that eating out of phase with the endogenous clock results in desynchronization between rhythms of the central and peripheral clock systems and between rhythms of different tissue clocks (eg, liver and muscle clock). Glucose homeostasis is a complex process that involves multiple organs. In the healthiest situation, functional rhythms of these organs are synchronized. We hypothesize that desynchronization between different metabolically active organs contributes to alterations in glucose homeostasis. Here we summarize the most recent information on desynchronization between organs due to shift work and shifted food intake patterns and introduce the concept of phenotypic flexibility, a validated test to assess the contribution of each organ to insulin resistance (IR) in humans. We propose this test as a way to provide further insight into the possible desynchronization between tissue clocks. Because different types of IR benefit from different therapeutic approaches, we also describe different chronotherapeutic strategies to promote synchrony within and between metabolically active organs.

ASSESSMENT OF ANTHROPOMETRIC AND IRON STATUS OF SCHOOL CHILDREN IN SOMOLU LOCAL GOVERNMENT AREA OF LAGOS STATE, NIGERIA

Iron is essential for children's cognition because it enhances behavioural and intellectual performance and promotes the body's resistance to infections. However, the risk of iron deficiency increases during period of rapid growth notably among school aged children in developing countries. This study assessed the anthropometric and iron status of school children in Somolu Local Government Area of Lagos State. Somolu Local Government was selected using purposive sampling. One hundred and forty school children (8-12 years) were selected from 3 primary schools using multistage sampling technique. Socio economic data were collected using structured questionnaire. Nutritional status of pupils were assessed using anthropometric measurements while iron status was determined using biochemical analyses of serum ferritin (SF), packed cell volume (PCV) and haemoglobin (H-B). Socio economic data were analysed with descriptive statistic (frequency, mean and percentages). While Chi-square and Pearson product moment correlation were used to establish relationship between variables. Pattern of dietary iron sources intake of the respondents were determined using food frequency questionnaire. Result showed that mean values of weight, height, haemoglobin, packed cell volume and ferritin were 43.82kg, 141.67cm, 11.50g/dl, 33.91% and 49.10ng/l respectively. Results of Anthropometric assessment indicated that 18.2% of female and 12.7% male were stunted; 15.6% of female and 14.30% of male were wasted, while 27.3% of the female and 23.0% of the male were underweight. 67% of the subjects had normal ferritin (15-100ng/l), 19.0% had low ferritin (<15ng/l) while 14.3% had abnormal high ferritin (>100ng/l). The respondents (14.3%) whose ferritin level were exceedingly high (>100ng/l) belong to AC (4.7%), SC (3.5%), and SS (6.1%) genotype blood'groups. Findings also revealed that 24.2% of the male and 33.0% of female respondents were anaemic (Hb<11g/dl). 81.43% of the respondents consume less of iron rich food. The haemoglobinlevel of the male respondents were found to be positively correlated with their BMI. (r = 0.289, P > 0.05). There was a positive correlation between PCV and BMI of male respondents (r = 0.209., P < 0.05). Furthermore, there was a relationship between blood Ferriftin and genotype of both male and female respondents respectively (r = 0.276, P < 0.05), (r = 0.341, P < 0.05). A positive correlation existed between ferritin and food intake pattern of female respondents (r = 0.288, P < 0.05). There was a negative correlation between iron status and income of the respondents' parents, (r = 0.276, P < 0.05). In conclusion, this study has ascertained that there is stunting, wasting, underweight and iron deficiency among school children in Somolu Local Government Area of Lagos State. It is recommended that appropriate intervention should be introduced to reduce the prevalence of iron deficiency among school aged children in Somolu Local Government Area.

Associations between nutrient intakes and dietary patterns with different sarcopenia definitions in older Australian men: the concord health and ageing in men project.

To assess the associations between nutrient intake and dietary patterns with different sarcopenia definitions in older men. Cross-sectional study. Sarcopenia was defined using the Foundation for the National Institutes of Health (FNIH), the European Working Group on Sarcopenia in Older People (EWGSOP) and the European Working Group on Sarcopenia in Older People 2 (EWGSOP2). Dietary adequacy of fourteen nutrients was assessed by comparing participants' intakes with the Nutrient Reference Values (NRV). Attainment of NRV for nutrients was incorporated into a variable 'poor' (meeting ≤ 9) v. 'good' (meeting ≥ 10) using the cut-point method. Also, two different dietary patterns, monounsaturated:saturated fat and n-6:n-3 fatty acids ratio and individual nutrients were used as predictor variables. A total of 794 men aged ≥75 years participated in this study. The prevalence of sarcopenia by the FNIH, EWGSOP and EWGSOP2 definitions was 12·9 %, 12·9 % and 19·6 %, respectively. With the adjustment, poor nutrient intake was significantly associated with FNIH-defined sarcopenia (OR: 2·07 (95 % CI 1·16, 3·67)), but not with EWGSOP and EWGSPOP2 definitions. The lowest and second-lowest quartiles of protein, Mg and Ca and the lowest quartiles of n-6 PUFA and n-3 PUFA intakes were significantly associated with FNIH-defined sarcopenia. Each unit decrease in n-6:n-3 ratio was significantly associated with a 9 % increased risk of FNIH-defined sarcopenia (OR: 1·09 (95 % CI 1·04, 1·16)). Inadequate intakes of nutrients are associated with FNIH-defined sarcopenia in older men, but not with the other two sarcopenia definitions. Further studies are required to understand these relationships.

Loss of CTRP4 alters adiposity and food intake behaviors in obese mice.

Central and peripheral mechanisms are both required for proper control of energy homeostasis. Among circulating plasma proteins, C1q/TNF-related proteins (CTRPs) have recently emerged as important regulators of sugar and fat metabolism. CTRP4, expressed in brain and adipose tissue, is unique among the family members in having two tandem globular C1q domains. We previously showed that central administration of recombinant CTRP4 suppresses food intake, suggesting a central nervous system role in regulating ingestive physiology. Whether this effect is pharmacological or physiological remains unclear. We used a loss-of-function knockout (KO) mouse model to clarify the physiological role of CTRP4. Under basal conditions, CTRP4 deficiency increased serum cholesterol levels and impaired glucose tolerance in male but not female mice fed a control low-fat diet. When challenged with a high-fat diet, male and female KO mice responded differently to weight gain and had different food intake patterns. On an obesogenic diet, male KO mice had similar weight gain as wild-type littermates. When fed ad libitum, KO male mice had greater meal number, shorter intermeal interval, and reduced satiety ratio. Female KO mice, in contrast, had lower body weight and adiposity. In the refeeding period following food deprivation, female KO mice had significantly higher food intake due to longer meal duration and reduced satiety ratio. Collectively, our data provide genetic evidence for a sex-dependent physiological role of CTRP4 in modulating food intake patterns and systemic energy metabolism.

Prospects of circadian clock in joint cartilage development.

Altering the food intake, exercise, and sleep patterns have a great influence on the homeostasis of the biological clock. This leads to accelerated aging of the articular cartilage, susceptibility to arthropathy and other aspects. Deficiency or overexpression of certain circadian clock-related genes accelerates the cartilage deterioration and leads to phenotypic variation in different joints. The process of joint cartilage development includes the formation of joint site, interzone, joint cavitation, epiphyseal ossification center, and cartilage maturation. The mechanism by which, biological clock regulates the cell-cycle, growth, metabolism, and other biological processes of chondrocytes is poorly understood. Here, we summarized the interaction between biological clock proteins and developmental pathways in chondrogenesis and provided the evidence from other tissues that further predicts the molecular patterns of these protein-protein networks in activation, proliferation, and differentiation. The purpose of this review is to gain deeper understanding of the evolution of cartilage and its irreversibility seen in damage and aging.

Nutritional implications of opioid use disorder: A guide for drug treatment providers.

The number of Americans seeking treatment for opioid use disorder (OUD) continues to increase. However, there are important nutritional implications of having OUD that often get overlooked by drug treatment providers. OUDs can cause metabolic changes, constipation, and weight loss, or lead to a lifestyle that results in inadequate food intake and unhealthy eating patterns. Nutritional factors associated with OUD can also hinder treatment outcomes and recovery. Addiction providers tend to give little attention to the nutritional implications of OUD, and this knowledge is rarely incorporated into treatment plans. The goal of this article, therefore, is to summarize the existing literature on the connection between OUD and nutrition to help guide treatment programs. This article (a) describes the nutritional consequences associated with misusing opioids, (b) discusses the role that nutrition can play in OUD treatment and recovery, (c) summarizes the nutritional implications of medication treatment for OUD, and (d) recommends nutritional interventions that might aid in the treatment of OUD. This article directly fills a gap in the OUD literature and has the potential to serve as a guide for drug treatment providers to make more informed nutritional recommendations to their clients. Treatment programs may wish to consider the issues raised in this paper before launching nutritional programs at their facility. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Patterns of food parenting practices regarding junk food and sugary drinks among parent-child dyads

BackgroundChildren’s food preference and intake patterns are affected by parental child feeding practices. The objective was to determine patterns of food parenting practices regarding junk food and sugary drinks (JS) and investigate their associations with demographic characteristics and dietary intake in a large cohort of parents and their children (12–17 years).MethodsDyadic survey data from the cross-sectional, internet-based Family Life, Activity, Sun, Health, and Eating Study, conducted in 2014, were analyzed using latent class analysis to identify patterns of use for six JS parenting practices – negative emotions, restriction, monitoring, availability, modeling, and child involvement – based on parent and child report. Model covariates included self-reported parent and child sex, age (child only), body mass index category (based on height and weight), added sugars intake, and legitimacy of parental authority.ResultsBased on 1657 parent-child dyads, five parenting practice patterns were identified representing different levels of practice use – Complete Influencers (28%; reference class), Indifferent Influencers (21%), Negative Influencers (20%), Minimal Influencers (18%), and Disagreeing Influencers (13%). Compared to older child dyads, younger child dyads were less likely to belong to Indifferent and Minimal Influencers (79 and 63% lower odds, respectively). Greater parent added sugars intake increased the odds of belonging to Indifferent and Negative Influencers (4 and 5% higher for every teaspoon increase, respectively) while greater child added sugars intake decreased the odds of belonging to Minimal Influencers (6% lower for every teaspoon increase). Compared to dyads with high scores, dyads with low child scores for legitimacy of parental authority regarding JS were 18 times as likely to belong to Disagreeing Influencers.ConclusionsThe study findings suggest that parents utilize distinct patterns of feeding practices regarding JS ranging from use of many practices, use of some practices, to low use of any practice, with differential associations with parent and child intakes of added sugars. Counseling or intervening with parents to use a mix of structure practices, such as availability and modeling, to positively influence their child’s and possibly their own intake of sugary snacks and drinks may prove more efficacious than use of coercive control practices, such as negative emotions.

Targeting the gut microbiota by Asian and Western dietary constituents: a new avenue for diabetes.

Increasing numerous diabetes annually is a great concern in public health globally. Gut microbiota recently has been suggested to be an emerging organ acting as a critical regulator in diabetes. Notably, gut microbiota is closely affected through an individual's nutrient intake and dietary pattern. Moreover, the metabolites of diets through gut microbiota are closely associated with the development of diabetes. Increasing evidence has established the association of different dietary pattern with alterations of the gut microbiota profile, in particular, the Asian diet and Western diet are typically as essential components linked to the interactions between gut microbiota and induction of obesity which is a significant risk factor for diabetes. In addition, some bacteria-related therapeutic methods including probiotics, dietary short-chain fatty acids immunotherapy, and gut microbiome transfer would be applied in the clinical prevention and control diabetes. Taken together, based on current published observations, the gut microbiota may serve as regulator or targets by the Asian diet and Western diet, contributing to the prevention or induction of diabetes eventually. In general, in the upcoming future, one of the emerging strategies for the prevention and control of diabetes may modulate gut microbiota through precise dietary strategies.

Effect of a nutrition education programme on the metabolic syndrome in type 2 diabetes mellitus patients at a level 5 Hospital in Kenya: \u201ca randomized controlled trial\u201d

BackgroundType 2 diabetes mellitus (T2D), is a life-threatening condition of global public health concern. It worsens in the presence of the metabolic syndrome (MetS), a complex disorder characterized by co-occurrence of at least three of such factors as hypertension, obesity, dyslipidemia and insulin resistance. However, lifestyle interventions reduce the risk of both MetS and T2D, and nutrition education can empower individuals on the appropriate, lifestyle changes. The aim of the current study was to evaluate the effect of a nutrition education programme, with and without inclusion of peer to peer support, on MetS in T2D patients.MethodsThis was a randomized controlled trial with two intervention groups and one control. One of the intervention groups involved a nutrition education programme with peer-to-peer support (NEP); the other involved only the education program, while the control received standard care. Each group had 51 participants. The nutrition education programme was conducted for 2 h per week for 8 weeks. In addition, the NEP had weekly peer-to-peer interactions for 8 weeks. All groups had follow-up sessions for 6 months. Data on MetS risk factors as well as food intake patterns and physical activity levels were taken at baseline and at different time points during the study. Analysis of Co-variance and regression were used in the analysis.ResultsThe MetS prevalence improved in the NEP (90 to 52%) and NE (86 to 69%), while it worsened in C (88 to 91%). There was improvement in the mean values of the anthropometric parameters in the NEP and NE which worsened in the control group. There was a general improvement in mean values of blood lipids, fasting blood glucose and HbA1c in all the groups, with NEP showing the greatest improvements, followed by NE, except for triglycerides and HDL where the control group had better improvement than the NE. Changes in the anthropometric and metabolic indicators mirrored the changes in food intake patterns and physical activity, where the greatest improvements occurred in the NEP.ConclusionsNutrition education with inclusion of peer to peer support was of clinical benefit in improving metabolic outcomes and reducing MetS in T2DM patients.Trial registrationThe study has been registered retrospectively by Pan African Clinical Trial Registry; Registration No: PACTR201910518676391.

The Role of Diets in Prevention and Hypertension Therapy

Hypertension is one of the public health problems in the world in the last decade. Various studies show hypertension is a major risk factor in the occurrence of stroke, ischemic heart disease, and kidney failure. Hypertension therapy can reduce the risk of stroke by 40% and myocardial infarction risk by up to 15%. Lifestyle changes that are part of the management of hypertension can reduce blood pressure, increase the effectiveness of antihypertensive drugs, and reduce cardiovascular risk. Modification of daily food intake patterns is one component of lifestyle changes that have the greatest role in lowering blood pressure. Modification of food intake patterns referred to is to follow the general guidelines for balanced nutrition also in accordance with the dietary approach to stop hypertension (DASH), which is high in vegetables and fruit, high-fiber foods, low-fat milk, meat, and nuts. It should also be noted that energy intake, the amount and type of protein, and fat and carbohydrate components. In addition, foodstuffs are rich in minerals and vitamins, and specific nutrients, such as omega-3 unsaturated fatty acids have a role in the prevention and management of hypertension.

The Role of Diets in Prevention and Hypertension Therapy

Hypertension is one of the public health problems in the world in the last decade. Various studies show hypertension is a major risk factor in the occurrence of stroke, ischemic heart disease, and kidney failure. Hypertension therapy can reduce the risk of stroke by 40% and myocardial infarction risk by up to 15%. Lifestyle changes that are part of the management of hypertension can reduce blood pressure, increase the effectiveness of antihypertensive drugs, and reduce cardiovascular risk. Modification of daily food intake patterns is one component of lifestyle changes that have the greatest role in lowering blood pressure. Modification of food intake patterns referred to is to follow the general guidelines for balanced nutrition also in accordance with the dietary approach to stop hypertension (DASH), which is high in vegetables and fruit, high-fiber foods, low-fat milk, meat, and nuts. It should also be noted that energy intake, the amount and type of protein, and fat and carbohydrate components. In addition, foodstuffs are rich in minerals and vitamins, and specific nutrients, such as omega-3 unsaturated fatty acids have a role in the prevention and management of hypertension.

Association of Food Intake Patterns and Parents’ Educational Levels with Nutritional Statuses of School-Going Children (5-13 years old) in Rural Areas of Northern Bangladesh

Association of Food Intake Patterns and Parents’ Educational Levels with Nutritional Statuses of School-Going Children (5-13 years old) in Rural Areas of Northern Bangladesh

Nutrient patterns and their relationship with general and central obesity in US adults.

Despite growing evidence on the associations between nutrient patterns and obesity, very few studies have examined the association between patterns of nutrient intake and obesity. To identify major nutrient patterns in U.S. adults and investigate their association with general and central obesity. National Health and Nutrition Examination Survey (NHANES) participants from 2005 to 2012 were included. General obesity was defined as body mass index ≥30 kg/m2, and central obesity as a waist circumference >102 cm for men and >88 cm for women. Intakes of 60 nutrients were calculated. Factor analysis was applied to derive the major nutrient patterns. Statistical analyses accounted for the survey design and sample weights. Overall 24,182 eligible individuals including 8155 with general obesity and 11730 with central obesity were included. Three nutrient patterns explaining 50.8% of the variance in dietary nutrients consumption, were identified. The odds of all types of obesity increased across quarters of the first nutrient patterns (mostly representative of saturated/mono-unsaturated fatty acids), such that the fourth quarter was associated with odds ratio of 1.31 (95%CI: 1.13-1.51) for general obesity and 1.47 (95%CI: 1.30-1.66) for central obesity, relative to the first quarter. The second nutrient patterns (mostly representative of micro nutrients and vitamins) was associated with lower odds of general [0.32 (95%CI: 0.61-0.77]) or central obesity [0.31 (95%CI: 0.62-0.78). Nutrient patterns may have deleterious or protective effects on the risk of general and central obesity, with implication for food-based strategies to prevent and control obesity. This article is protected by copyright. All rights reserved.

Trichosanthes dioica Roxb. prevents hepatic inflammation and fibrosis in CCl4-induced ovariectomized rats

Summary Plant-derived natural products have shown beneficial effects in many diseases associated with liver. The present study aimed to appraise the effects of Trichosanthes dioica (TD) peel extract on oxidative stress, inflammation as well as fibrosis exhibited by the ovariectomized rats in which hepatic damage had been induced by the administration of carbon tetrachloride (CCl4). The CCl4 administration in the ovariectomized rats elevated the plasma ALT, AST, and ALP level in comparison with the control while TD peel extract showed significant reduction of those activities. Besides, oxidative stress and lipid peroxidation also increased in CCl4-treated rats. TD peel extract significantly reduced the oxidative stress marker's concentration and improved the catalase and SOD activities in CCl4-administered ovariectomized rats. These results suggest that TD peel extract is capable of protecting the liver from CCl4induced damage through preventing oxidative stress, lipid peroxidation, inflammation, fibrosis and boosting the diminished cellular antioxidant defense.