Objective To understand the basic characteristics of elderly patients in the Comprehensive Ward of emergency department, put forward reliable countermeasures that can be applied to clinical nursing work, in order to provide reliable countermeasures for clinical nursing work. Methods By querying the electronic medical record system, we collected data from patients retrospectively, and used statistical inference and cluster analysis, nonparametric rank sum test and other statistical inference methods to analyze the data. Results Totally 636 patients were included, the average age of 83 years (77,87), the average required nursing project 4 (3,5), the average number of diagnosis 8 (6,11), Charlson comorbidity index (2,5) with an average of 4 points, the average hospitalization was 15 days (11,21); diagnosis the number of top five diseases for acute exacerbation of chronic obstructive pulmonary disease, pneumonia, pulmonary infection, hypostatic pneumonia, aspiration pneumonia and acute exacerbation of chronic heart failure; 15 nursing needs are divided into three categories before statistical analysis, basic nursing, nursing, nursing treatment pipeline, and as cluster variables in 636 patients divided into three groups, which were high demand for nursing care group, nursing group, nursing group needs low demand. The three groups of patients were statistically significant in the number of deaths, age, Charlson complication index, the number of clear diagnosis and the days of hospitalization (P<0.05). Conclusion The average age of hospitalized elderly patients is relatively high. The risk of death is gradually increased after the patients are grouped according to the requirement of nursing. They are more likely to merge more diseases. The number of hospitalized patients is longer and the number of deaths will increase. Clinical nursing staff should recognize the nursing needs of different types of patients and provide better quality care services for them. Key words: Aged; Nursing care; Emergency; Countermeasures; Cluster analysis