The influence of a uniaxial distributed load in the plane of a thin rectangular plate on the value of the first natural frequency of its oscillations has been studied. We considered a plate, two opposite faces of which are clamped, and the other two are free (CFCF-plate, C-clamped edge, F-free edge). The load is applied to the clamped edges. The main differential equation for the coordinate component of the deflection function and all the boundary conditions of the problem are fulfilled exactly using two hyperbolic-trigonometric series in two coordinates and an additional function depending on one variable x. The problem was reduced to an infinite system of linear algebraic equations with respect to one sequence of uncertain coefficients, containing as parameters the magnitude of the load and the frequency of oscillations. For a number of load values, the natural frequencies of oscillations were found by enumerating frequency values in combination with the method of successive approximations when solving a reduced system of linear algebraic equations. To ensure acceptable accuracy of calculations, the number of terms in the series (the size of the reduced system), the number of iterations and the number of significant digits in the mantissa when calculating non-trivial coefficients of the system were changed. A square plate was considered as an example. Based on the calculation results, a graph was constructed of the dependence of the first natural frequency of oscillations on the magnitude of tension-compression forces, which is a curve close to a parabola. Under Eulerian compressive load, the oscillations stop. The shapes of natural vibrations changed slightly and were similar to the shape of the curved surface of a plate under the action of a uniform transverse load. The purpose of this study is to create an effective algorithm for calculating the natural frequencies of oscillations of a CFCF-plate when the uniaxial tensile-compression load of its clamped faces changes.