Urban resilience provides the foundation and guarantee for the tourism economy, and the development of the tourism industry provides new opportunities and impetus for urban resilience. The coordinated development of urban resilience (UR) and the tourism economy (TE) contributes to the high-quality development of the regional economy. This study takes 27 cities in the Yangtze River Delta (YRD) urban agglomeration as an example. Various analytical techniques, including the entropy method, coupling coordination degree model (CCDM), kernel density estimation, Theil index, and obstacle degree model, are employed to investigate the spatiotemporal evolution patterns and influencing factors that affect the coupling coordination degree (CCD) between UR and TE. The findings indicate that: (1) The urban resilience and tourism economy exhibited an increasing trend denoted by “N” and “M”, respectively. (2) The coupling coordination level has undergone a development phase of “Moderate disorder–Bare coordination–Moderate disorder”. (3) The level of coordination has been enhanced, with intra-regional differences identified as the primary source of variation. (4) The number of Internet users, the number of students in institutions of higher learning, per capita public financial expenditure, science and technology expenditures as a share of fiscal expenditures, urban per capita disposable income, foreign exchange earnings from tourism, and the number of inbound tourists is the main factors affecting the CCD of urban resilience and tourism economy.