Novosibirsk Region Research Articles

Clinical and laboratory characteristics of Q fever in the Novosibirsk region

Clinical and laboratory characteristics of Q fever in the Novosibirsk region

Reproductive Behavior of Adolescent Girls: Analysis of Risk Factors, Prospects of Prevention and Education

INTRODUCTION: Caring of reproductive health of children and adolescents in the society, especially of adolescent girls as a group most vulnerable to risks in the reproductive sphere, continues to be of high importance. The studies confirm that education and awareness about reproductive health can reduce the probability of problems occurring. The existing legal regulations emphasize the importance of providing accurate and timely information of reproductive health. AIM: Scientific justification of the strategy of forming safe reproductive behavior of adolescent girls on the basis of the peculiarities of their current reproductive behavior taking into account the opinion of specialists in the fields of education and healthcare. MATERIALS AND METHODS: To assess the peculiarities of reproductive behavior of adolescent girls, an anonymous questionnaire survey of 400 adolescent girls was conducted. To determine the expectations of the participants of the sex education process, as well as the main directions of preventive work and education, a survey of 400 parents of adolescent girls, 86 pediatricians, 34 obstetricians-gynecologists and 420 teachers was conducted. For all groups of participants, author’s questionnaires were developed. RESULTS: The reproductive behavior of adolescent girls living in the territory of the Novosibirsk region, is characterized by early start of sex life (15.90 ± 0.14 years), promiscuity (1.70 ± 1.10 partners), refusal to use effective means of contraception. Parents of adolescent girls emphasize the leading role of the family in sex education, suggesting participation of doctors and teachers in the process, but remain dissatisfied with the intensity of preventive measures. A similar problem is emphasized by specialists in the healthcare and education systems who indicate the possibility of conducting preventive work with adolescent girls remotely. In the opinion of pediatricians and obstetricians-gynecologists, providing preventive information on the reproductive health and behavior, will not only create safe reproductive behavior for modern adolescents, but is also an effective strategy of improving the system of reproductive health protection. CONCLUSION: The study identified features of the reproductive behavior of adolescent girls that characterize it as risky. The results emphasize the need for an integrated approach to assessing and maintaining the health of adolescent girls, and also focus attention on the importance of educational work in this age group. The study serves as a basis for further preventive strategies in the field of reproductive health and education.

Effectiveness of organizational and legal measures and new practices to against HIV infection in the Novosibirsk region

The purpose of the study: to study the effectiveness of organizational and legal measures and new practices to against HIV infection introduced in the Novosibirsk region in 2019–2022.Materials and methods. The study was conducted on the basis of the State Medical Institution of the NGO «City Infectious Clinical Hospital No. 1», a division of the Center for the Prevention and Control of AIDS.Results. By Order of the Ministry of Health of the Novosibirsk Region No. 3429 of 10/15/2019, mandatory HIV screening was provided for all hospitalized with unknown HIV status during the year, which significantly increased the coverage of HIV screening. In 2019–2022, an AIDS Center information system was introduced for all patients with HIV infection admitted to inpatient treatment: 6,938 notifications were sent to the AIDS Center. Of the 2,717 patients who required measures to increase the level of adherence and involvement in ART, 18.9% of patients resumed ART after the measures taken; 36.5% started taking ART for the first time. The order of the State Medical Institution of the Infectious Clinical Hospital № 247 «On the organization of family support in the department «Center for the Prevention and Control of AIDS» dated 02.08.2021 provides the principle of monitoring the whole family with one doctor, which improves the adherence of children and parents to ART. For 4 months of functioning of family support, the share of parents receiving ART and having a high commitment increased from 15.5% to 77.3%. Among 45 children who had a previously determined level of HIV RNA viral load on the background of ART, 20% (9 abs.) registered an undetectable level of viral load for 3 months, and 13.3% (6 abs.) – for 2 months.Conclusion. The organizational and legal measures implemented in 2019–2022 in the Novosibirsk region and new practices to combat HIV infection have shown high efficiency: the coverage of dispensary observation of patients with HIV infection increased from 79.3% to 86.5%, and the coverage of antiretroviral therapy – from 74.5% to 85.2%.

Развитие демографического потенциала сельских территорий в целях обеспечения их социально-экономического развития (на примере Новосибирской области)

Introduction. The article considers opportunities to improve demographic potential as a critical factor influencing the socio-economic development of rural areas.Materials and methods. To study the actual demographic situation in the Novosibirsk region and the regions of the Siberian Federal District, statistical analysis methods were used - index, tabular methods, etc. The empirical basis for this was the data of the Federal State Statistics Service, including the Territorial Authority for the Novosibirsk Region, on demographic processes in the Novosibirsk region for the 2010-2023 period (population size, structure, natural increase, migration increase, migration balance, total population growth rate, birth and death rate, average life expectancy).To analyze the implementation of the strategy for sustainable development of rural areas in the Russian Federation, a retrospective method was used, with the help of which the persistence of negative demographic trends in rural areas was shown.To work out recommendations for the development of corporate social policy directions for large organizations of the agro-industrial complex, the authors relied on strategic and systemic analysis methods to identify the potential and develop measures of corporate social policy of agricultural producers in the Novosibirsk region.Results. Consideration of the all-Russian situation regarding the development of rural areas showed that it is necessary to pay more attention to the development of the demographic potential of these territories. At the level of the Novosibirsk region, an analysis of the legislative framework allowed us to conclude that it is necessary to actively attract young people to rural areas, retaining them in agricultural enterprises, providing efficient employment and at the same time promoting the socio-economic development of rural areas.Discussion. Ensuring sustainable development of rural areas is impossible without solving demographic problems based on a regional demographic policy considering the interests of young rural families, and corporate demographic policy implementation at the level of agricultural enterprises.

Оценка химического состава сапропелей различных месторождений

Complex chemical composition and wide mining opportunities determine the use of sapropels and sapropel-based products in various sectors of national economy. The fullest potential of sapropel is revealed in agriculture, where it is used as fertilizer, a component of soils, raw materials for humic preparations production etc. The aim was to study the sapropels’ suitability for the production of humic fertilizers. Using validated methods we analyze chemical composition of sapropel sediments from 4 freshwater lakes located within the latitudinal section of 53–56° N in the temperate climate. Microbiological parameters of all studied samples are within the normal range. Dry matter content in the range of 46.1–51.3% corresponds to the normative indicators. The mass fraction of organic matter varies in the range of 31.8–39.9% DM. This allows classifying all samples as organo-clay, and determines the possibility of their use for soils of light granulometric composition. The relatively high content of humic (18.3–22.9% DM) and fulvic acids (3.7–6.4% DM) makes it possible to use the studied sapropel samples for the manufacture of humic preparations (especially, a sapropel sample of the lake Chervonoe, Belarus). Low P and K content (0.24–0.36% DM and 0.32–0.42% DM, respectively) can negatively affect the efficiency of fertilizers from these sapropel species; this can be avoided by mixing sapropel with manure or enrichment with mineral fertilizers. Indicators of heavy metal (Cu, Mn, Zn, Co, Pb and Cd) content in all studied samples meet the safety requirements. Samples from deeper layers of the Rusaki Lake (Altai Territory) and the Beloe Lake (Novosibirsk Region) refer to the 1st class of suitability, the rest (according to a number of indicators) – to the 2nd class. The content of trace elements in the studied sapropels is within the established norms and makes it possible to use them for replenishing the deficit of trace elements in soils. In general, all the studied samples can be used as environmentally friendly organomineral fertilizers, as well as production of humic preparations to increase in the biological and energy capacity of agrocenoses and to reproduce the soil fertility.

Public Assessment of the Activities of Natural Monopolies in the Novosibirsk Region

Public Assessment of the Activities of Natural Monopolies in the Novosibirsk Region

Characteristics of chronic non-bacterial osteomyelitis in children living in the Novosibirsk region

Characteristics of chronic non-bacterial osteomyelitis in children living in the Novosibirsk region

Monitoring the Training of School Management Teams in Educational Institutions of the Novosibirsk Region

Introduction. The article discusses topical problems of team building typical for state educational organizations. The problems of team formation, formal leadership and the differences between a team and a working group are considered. The purpose of this article is to present the methodological grounds for the use of team building in the management activities of school leaders, as well as to show the monitoring of the training of management teams in the Novosibirsk region. Methodology. The study of the possibilities of using the technology of team building in the organization of innovative activities of teachers of educational organizations (on the example of management teams of schools in the Novosibirsk region) was carried out in several stages: organizational, diagnostic, approbation, and reflexive-evaluative. The purpose of the monitoring was to study the conditions created for the professional growth of members of school management teams at the regional and municipal levels, as well as the demand for various forms of training. Also, in the course of monitoring, information was collected on organizations that train management teams. Results. The analysis of the information provided has shown that the heads of general educational organizations and representatives of municipal educational authorities often do not understand what the concept of “training of management teams” includes and often replace it with a referral to advanced training courses and training events of the group. Conclusion. The monitoring recorded the need to form a system of work at the regional and municipal levels to organize the training of school management teams. Heads of educational institutions should consciously approach the issues of team building and assess the need to create a team based on the actual need.

Potato productivity on the background of the entomopathogenic fungus <i>Metarhizium robertsii</i> application in production trials

For the first time in Western Siberia (Novosibirsk region), two-year production trials of an experimental prototype of a drug based on the entomopathogenic fungus Metarhizium robertsii have been conducted. Strain P-72 isolated from the dead larvae of Colorado potato beetle Leptinotarsa decemlineata Say from the collection of microorganisms of the Institute of Systematics and Ecology of Animals of the Siberian Branch of the Russian Academy of Sciences was used in this work. Species identification of the fungus was performed based on sequencing of the elongation factor gene region EF1α. The ability of the preparation to significantly increase the parameters of potato yield structure elements throughout the whole vegetation period was shown. A reliable increase in the number of surviving sprouts by 1.4 times, the number of stems and tubers by 1.5 times was found. The growth-stimulating effect of using the preparation based on entomopathogenic fungus was manifested in the increase of plant weight by the flowering phase. The average yield increase for two years amounted to 36.0% in the variant with application of M. robertsii significantly exceeding the productivity of potatoes in the control. The level of profitability of potato production with the use of entomopathogenic fungus M. robertsii increased to 92.0% (with 50.0% in the control) due to the increase in gross yield and improved quality of marketable products. Infestation of new harvest tubers with rhizoctoniose significantly decreased in the variant including treatment with entomopathogenic fungus: the number of tubers with sclerotia decreased 2.8 times compared to the control, which eventually led to an increase in the number of healthy tubers and a significant (2.5 times) decrease in the sclerotial index.

Evaluation of the genotypes of the Kazakh-Siberian nursery (KASIB) in the conditions of the Novosibirsk region

The paper presents the results of evaluation of the KASIB-22 nursery soft wheat samples resistance to the main wheat pathogens. The research material was 44 wheat samples obtained from different regions of Russia and Kazakhstan within the framework of the KASIB shuttle breeding program (A.I. Barayev Research and Production Centre for Grain Farming, Omsk State Agrarian University, ICiG SB RAS, Karabalyk AES, Karaganda AES, North-Kazakhstan AES, FSBSI "Omsk ASC", HE SAU of the Northern Trans-Urals, Aktyubinsk AES, Kurgan Research Institute of Agriculture, Pavlodar AES, agrokomplex "Kurgansemena", Samara Research Institute of Agriculture, Chelyabinsk Research Institute of Agriculture). The following breeding lines were identified as highly productive and possessing high and medium resistance to brown rust, powdery mildew and loose smut: Line Pt-311 (Kurgan Research Institute of Agriculture), Lutescens 1462, Lutescens 1486, Line1616ae14 (Samara Research Institute of Agriculture), Lutescens 1356 (ICiG SB RAS). The yield of the selected samples averaged 42.1–51.2 c/ha. Genotypes Novosibirskaya 41, Line 435/12 and Lutescens 1364 are of interest for selection for quality. The gluten content of the nursery genotypes ranged from 24.1 (Line 23/07 in 2022) to 38.0% (variety Astana 2 in 2021), protein ranged from 13.4 (variety Tertia in 2022) to 19.5% (Lutescens 1364 in 2022). Each of the selected lines is of practical value for breeding, and the samples from the KASIB-22 nursery allow to expand the genetic diversity of spring soft wheat by selecting the most resistant forms to local populations of powdery mildew, leaf rust and loose smut pathogens.

Opinion of medical and pharmaceutical professionals on the quality of pharmaceutical care for patients with diabetes mellitus in the Novosibirsk region: a comparative sociological study

Relevance. Patients with diabetes mellitus (DM) in the Russian Federation have the right to receive free medications. Despite this, some patients with DM experiencing difficulties at various stages of preferential treatment are forced to purchase medications at their own expense. Medical workers (MW) who receive patients and pharmaceutical workers (PW) of preferential dispensing points (PDP), who dispense drugs on preferential terms and provide pharmaceutical information (PI) to patients, are of considerable interest as competent sources of opinion about the quality of the organization of drug provision.Objective. To conduct a comparative sociological study of the organization of PDP for patients with DM in the Novosibirsk region (NSR) using the method of questioning MW and PW.Materials and methods. The materials used were the MW and PW questionnaires developed by the authors. During the study, the following methods were used: sociological survey (questioning), content analysis, comparative analysis, induction, and logical method.Results and discussion. 71% of MW must deal with various difficulties when issuing preferential prescriptions for drugs. These include: absence of drugs in the preferential list (29%), funding limit (29%), and absence of drugs in the PDP (35%). An average level of compliance in taking medications by patients with DM according to the MW was revealed, with a low interest in PI according to PDP workers. 45% of PW experience difficulties when conducting PI of patients with DM. The majority of PW (88%) consider the range of PDP in which they work to be rich in international nonproprietary names, trade names, and release forms of both oral hypoglycemic drugs and insulins.Conclusions. The results obtained allow us to conclude that the drug provision system for patients with DM in the NSR needs to be optimized. Based on the results of the survey, the main directions of optimization can be identified: increasing the availability of drugs in the PDP and increasing the competence of the PDP’s PW through the development of additional training materials and activities.

Estimation of adaptability parameters of winter common wheat samples at different sowing dates in the forest-steppe of Western Siberia

There has been presented a three-year estimation of winter wheat samples according to adaptability indicators, the trait ‘productivity’, ‘winter resistance’, ‘1000-grain weight’, and ‘number of productive stems per m2’. The purpose of the study was to estimate the adaptive potential of winter common wheat varieties in the forest-steppe of Western Siberia at different sowing dates. The study was conducted in the laboratory for field crop breeding, seed production and cultivation technologies based on SibRIPCB, the branch of Institute of Cytology and Genetics, SB RAS (Novosibirsk region) in 2018–2022. The objects of study were 5 winter common wheat varieties developed by the SibRIPCB, a branch of the Institute of Cytology and Genetics SB RAS. Sowing was carried out in three periods (the first was in August 20, the second was in September 1 and the third was in September 10) with an SSFC-7 seeder in 5 repetitions, the recording plot area was 10 m², the placement of the plots was randomized, the crops were laid in weedfree fallow. As a result, there was established that, according to the trait ‘productivity’, the varieties ‘Novosibirskaya 2’ (bi = 1.42; δd² = 0.08) and ‘Novosibirskaya 3’ (bi = 1.35; δd² = 0.08) combined ecological adaptability and stability. The variety ‘Novosibirskaya 3’ also combined adaptability and stability according to the trait ‘number of productive stems per m2’ (bi = 1.09; δd² = 468.94). The winter variety ‘Krasnoobskaya’ is capable of consistently giving high yields ((Ymax+Ymin)/2 = 4.92; (Sc = 3.42); Hom = 26.2) and maintaining the density of productive stems ((Ymin–Ymax) = -280; Sc = 280.8; (Ymin+Ymax)/2 = 513; Hom = 8.9) at different sowing dates. The variety ‘Pamyati Chekurova’ is responsive to improvements in environmental conditions according to the trait ‘productivity’ (bi = 1.10; KM = 2.20), ‘winter resistance’ (bi = 1.53; KM = 2.72), ‘number of productive stems per m2’ (bi = 1.22; KM = 2.2).

Наставничество в профессиональном образовании

The article analyzes the problem of mentoring in the framework of vocational education, examines the degree of personal relationships between mentor and mentee. It provides an opportunity to understand the importance and relevance of one of the forms of systematic transfer of knowledge and skills by a professional to a young specialist, which is mentoring. Representing the process of introducing a young specialist into professional activity. The author formulates the provisions that make it possible to comprehend the features of mentoring activities carried out by teachers of secondary vocational education in order to form an environment of qualitative formation and intensive development of the process of professional adaptation of a young specialist through mentoring in educational institutions of the Novosibirsk region.

Influence of humic preparations on the development of honeysuckle in the forest steppe of Western Siberia

Blue honeysuckle is a winter-hardy and unpretentious crop; in folk medicine, its berries and juice are used for hypertension, anemia, and intestinal disorders. The environmental situation and the general rise in prices of pesticides and mineral fertilizers stimulate the choice of alternative technologies and the use of biological plant protection products, growth stimulants, and bacterial fertilizers. In this regard, our research aimed to study the effect of various humic preparations on the growth and development of green cuttings of blue honeysuckle variety Berel. This variety has a medium ripening period, gives a high yield, is slightly crumbling, and is highly winter-hardy. The research was carried out in the Novosibirsk region on the territory of the Agro Seed Company in 2019 - 2021. The average annual growth and general condition of blue honeysuckle plants of the Berel variety were determined according to generally accepted methods. Data analysis showed that all studied indicators of honeysuckle plants are greatly influenced by the year’s conditions when the difference between years reaches 25 - 30%. In addition, it was found that all the studied drugs positively affect the growth and development of plants and, in particular, the survival rate and overwintering of green honeysuckle cuttings (up to 45%). Thus, the ZhT “Ekozhizn” preparation provided better survival and overwintering of plants. Cytohumate had a better effect on the development of vegetative mass, but in terms of survival and overwintering, it was inferior to using the ZhT “Ecozhizn” preparation.

The Use of Multipliers in Assessing the Economic Effects of Digital Transformation of Territories (Case Study: Novosibirsk Region)

Development of the digital transformation of the state, the economy in general, business and society creates the need to quantify its results and assess the level of impact on the economy. The paper explains a methodological approach to calculating digital economy multipliers for territories based on the calculation of total income (direct and indirect) from digital activity. The multiplier measures the impact of the digital economy on macroeconomic and regional indicators, helps assess the extent of this impact and study its dynamics. The authors calculated digital economy multipliers for the Russian Federation and at the regional level (using the example of the Novosibirsk region) and estimated total digital sector income with a multiplier effect. The paper concludes with the contribution of digital transformation to the economic growth of the Russian Federation and the development of the Novosibirsk region about the multiplier dynamics and the ratio of direct and indirect effects in the total income of the digital sector. Rosstat data for 2017–2021 served as the information base for empirical calculations.

Comparative assessment of the effectiveness of contact and systemic fungicides for treating soybean seeds in the forest-steppe of the Novosibirsk Region

Comparative assessment of the effectiveness of contact and systemic fungicides for treating soybean seeds in the forest-steppe of the Novosibirsk Region

Additions to the flora of the Novosibirsk Region

New adventive species for the Novosibirsk Region are reported: Arctium × ambiguum, Cephalaria gigantea, Corylus mandshurica, Elymus pendulinus., Narcissus pseudonarcissus, Nonea lutea, Ornithogalum umbellatum, Persicaria maculosa, Taraxacum dissimile, T. tenuilobum. New locations of rare species are indicated: Epipactis helleborine, Veronica persica, Veronica verna, the distribution of the species recently recorded in the Novosibirsk Region is noted.

Floristic findings in alien flora of the Novosibirsk Region

New alien species for the Novosibirsk Region are reported: Corydalis solida, Crataegus chlorosarca, Erigeron strigosus,Hemerocallis lilioasphodelus, Lathyrus oleraceus, Polygonum sabulosum, Ranunculus acris (Double Acris Group), Veronica biloba. New localities of rare alien species Astragalus contortuplicatus, Cerinthe minor, Cyclachaena xanthiifolia, Galium aparine, Myosotis stricta, Scleranthus annuus, Symphyotrichum novi-belgii, Symphytum × uplandicum were noted. For each species, its range is given, the distribution in the regions of Siberia is indicated.

The First Record of Omsk Hemorrhagic Fever Virus and Tick-Borne Encephalitis Virus of Baltic Lineage from the Kemerovo Region of Russia.

Objectives: Tick-borne encephalitis virus Siberian subtype (TBEV-Sib) and Omsk hemorrhagic fever virus (OHFV) are causative agents of natural focal infections in Western Siberia, Russia. The distribution of TBEV phylogenetic lineages and OHFV in the Kemerovo Region of Western Siberia remains poorly investigated. Methods: The phylogenetic analyses of fragment genome sequences 26 flaviviruses identified in 2019 were performed, and the amino acid variation was determined to reveal to which clusteron they belong. The age of Baltic and Asian lineages of the TBEV-Sib was calculated for Kemerovo District and Region, respectively. Results: Twenty-five isolates were members of three TBEV-Sib phylogenetic lineages: Baltic (48%), Asian (36%), and East Siberian (16%). The Baltic lineage's eastern boundary is commonly thought to be in the Novosibirsk Region, but our data suggest that it may reach further east. Analysis of the Baltic lineage clusteron structure showed that the isolates found are unique (6) or belong to clusteron-founder 3D (1) and derived clusteron 3O (5). Based on the age of 3O clusteron, Baltic lineage could have appeared in the Kemerovo Region by the late 1970s. One of the isolated viruses turned out to be the OHFV of the first subtype and not to belong to any known clusteron. This finding is the first known detection of the virus outside the endemic area of Russia. Given the recent discovery of OHFV in Kazakhstan, it can be assumed that the area of this virus distribution is much wider than previously thought. Conclusions: This report provides insights into the population structure of TBEV and OHFV, which may be helpful for epidemiological investigation and surveillance of the viruses.

Генотипическая характеристика штаммов Bordetella pertussis — кандидатов для получения коклюшного компонента вакцинных препаратов (сообщение I)

Vaccination is an effective means of preventing pertussis infection. The purpose of this work was to improve vaccines available in the Russian Federation in general and actualize vaccine strains used for the production thereof in particular. We studied B. pertussis strains isolated in Moscow, Voronezh, Novosibirsk, Ulyanovsk and Chelyabinsk regions, and eight production strains part of the adsorbed diphtheria-pertussis-tetanus (DPT) vaccine. Multilocus antigenic sequence typing (MAST) and whole genome multilocus sequence typing (wgMLST) were used for genotyping. We studied cultural morphological, enzymatic, serological, and genotypic properties of the candidate B. pertussis strains, and compared their genotypic properties to those of B. pertussis vaccine strains from the current composition of the DPT vaccine. Candidate strains belong to four genotypes: ptxА1/ptxВ2/ptxС2/ptxР3/fim2-2/fim3-2/prn2, ptxА1/ptxВ2/ptxС2/ptxР3/fim2-2/fim3-2/prn9, ptxА1/ptxВ2/ptxС2/ptxР3/fim2-1/fim3-1/prn1 and ptxА1/ptxВ2/ptxС2/ptxР3/fim2-2/fim3-1/prn2. Current vaccine strains were from other six genotypes: ptxА2/ptxВ1/ptxС1/ptxР1/fim2-1/fim3-1/prn1, ptxА2/ptxВ2/ptxС1/ptxР2/fim2-1/fim3-1/prn1, ptxА4/ptxВ1/ptxС1/ptxР2/fim2-1/fim3-1/prn1, ptxА2/ptxВ2/ptxС1/ptxР1/fim2-1/fim3-1/prn1, ptxА4/ptxВ2/ptxС1/ptxР2/fim2-1/fim3-1/prn1 and ptxА1/ptxВ2/ptxС1/ptxР1/fim2-1/fim3-1/prn1. With the help of wgMLST, we established affiliation of all candidate strains of B. pertussis to ST2.