We have analyzed influence of various innovations on economic activity efficiency. Innovations are subdivided into two types according to criteria: “novelty application field”; “degree of innovation novelty”. The first class includes technological, technical, economic, organizational, and management innovations, influence of which on the efficiency is performed directly through applied technologies and organizational and management structures. We have also distinguished a subclass of innovations of the said criterion influencing indirectly on the efficiency. Seminal, basic, improving, pseudo- and micro-innovations influence of which on enterprise activity happens indirect through intermediate institutions and mechanisms are ranges in the second class. Thus, increase of efficiency of an enterprise activity presupposes analysis of various innovation influence on manufacturing process characteristics and selecting of the most suitable ones.