North-West Federal District Research Articles

Atlas modernizatsii Rossii i ee regionov: Sotsioekonomicheskie i sotsiokul'turnye tendentsii i problemy ed. by N. I. Lapin

Reviewed by: Atlas modernizatsii Rossii i ee regionov: Sotsioekonomicheskie i sotsiokul'turnye tendentsii i problemy ed. by N. I. Lapin Rimma Tangalycheva (bio) N. I. Lapin, ed. Atlas modernizatsii Rossii i ee regionov: Sotsioekonomicheskie i sotsiokul'turnye tendentsii i problemy. 360 pp. Moscow: Ves Mir, 2016. ISBN 978-5-7777-0664-5. The work reviewed here represents an attempt to gain an understanding of new tendencies in the modernization of contemporary Russia and its regions. The authors' main focus is on the processes of the primary industrial stage of development in Russia and the transition to the secondary information stage. The authors aim to show the hierarchical differentiation of Russian federal subjects and federal districts in terms of modernization and to elicit contradictory tendencies in the regions' evolution. The significance of this research lies in its implications for the modernization program outlined by Dmitrii Medvedev in 2009. According to the authors' analysis, this program never resulted in the scientific development of a modernization strategy in Russia, let alone its practical implementation and regulation. The introductory section demonstrates the theoretical and methodological basis of their research, namely the concept of modernization as a civilizational process, and outlines the sociocultural challenges that Russian modernization has to tackle. In the following seven chapters, the authors consider processes, tendencies, and issues of modernization implemented between 2000 and 2012 in seven Russian federal districts. The authors connect Russian modernization processes with global development patterns. According to their data, approximately 90 developing countries are in the industrial stage of modernization and approximately 40 developed countries are in the informational stage, which points to the existence of multiple modernization processes. In a number of countries, including Russia, both stages of modernization are being implemented at the same time, with one type prevailing over the other in different parts of the country, thus indicating uneven modernization patterns in different regions. The novelty of the book is to be found in the authors' analysis of these uneven modernization processes in different parts of Russia. As this area of research is undeveloped, the Russian academy, the authors of this volume, follow the approach developed by the Center for Modernization Studies of the Academy of Sciences of China.1 Doing so enables the use of annual modernization indices in 130 countries with populations over one million (including the Russian Federation). Analyzing these indices reveals a great imbalance between Russian regions in the primary industrial and secondary information [End Page 135] stages of modernization—one that is two-and-a-half times as large as in other countries. In reaching this conclusion, the authors analyze a number of elements of modernization, including: • Technical and technological (indicators of transition to a new technological mode, which is becoming the main source of gross domestic income [GDI] in the country and in the regions, or a new resource for competitive development among other societies and states); • Socioeconomic (the growth of GDI per capita, the change in proportions of the main economic sectors, and human rights protection, excess of educational expenses, healthcare, and pension coverage); • Sociocultural (the human dimensions of fundamental human rights associated with working conditions, the level and quality of life of the people). • Institutional and regulatory (democratization of the state and political life of society, its judicial and legal institutions, ensuring the activity of civil society, counteracting the redundancy of bureaucratic control studies, and the number of officials engaged in the creation and implementation of these procedures). According to the authors of the book, between 2000 and 2012, the quality of modernization improved in all federal districts. At the same time, they note that only the former hierarchy of modernization has been modified. On the one end, the Central Federal District, including Moscow and the greater Moscow region, is considered to be developing dynamically. On the other, the Southern and North-Caucasian Federal Districts have risen from a low state to merely below average. The Volga, Siberian, and Far Eastern FDs were higher in terms of their secondary modernization levels. Regardless, all federal districts were at the stage of secondary modernization. At the same time, the Central Federal District rose above the Northwest Federal District, while the Ural Federal District still lags behind...

Risk-oriented approach to ensuring environmental safety of the devastated territories for urban development

The article considers the possibilities to improve the use of devastated territories of the Russian Federation, particularly of the Northwest Federal District and the Leningrad Oblast. The work provides data on monitoring the formation, usage and disposal of waste and outlines the range of environmental problems occurring due to exploitation of devastated territories. Measures of optimizing these territories, prospects for their implementation and related risks that may entail economic losses for urban development were determined in the article. This work reveals the important role of geoecological factors played in addressing the issues of preparing such areas for further building development. The study of characteristics and classification of devastated lands is of great importance for the rational planning of urban space. Successful rehabilitation of devastated lands enables their integration into the urban environment, the most effective usage and ensuring their social and economic potential growth for urban development.

Элементы формирования стратегии гармонизации межнациональных отношений в Северо-Западном федеральном округе

The main approaches to the formation of the strategy of harmonization of interethnic relations in the North-Western Federal District (hereinafter — NWFD) in the context of existing problems are considered. Formed the basic elements for the formation of a strategy for harmonization of interethnic relations, namely, legal, political, socio-cultural, economic. The statistical data that allow to draw a conclusion on the existence of a number of problems from the area of harmonization of interethnic relations in the Northwestern Federal District, including a low legal culture, gaps in legislation, insufficient communication between government and civil society, established national traditions and a high level of corruption of power. Approaches are proposed for forming a strategy for harmonizing interethnic relations taking into account the characteristics of the North-West Federal District.

Planning of the territory of large cities of Russia in the interests of their sustainable development

The paper reported here analyzes the practice of preparing documentation on territory planning in large cities of the North-West Federal district of Russia. Particular attention is paid to the development of projects on the basis of proposals of individuals or legal entities, as well as the search for effective tools for the development of cities of the North-West Federal district of Russia. The authors propose an alternative version of the interaction of local governments with potential investors on urban planning documentation. The mechanism of formation and updating of design solutions is based on a comprehensive assessment of incoming urban planning proposals of stakeholders.

THE STUDYOF THE АREA OF DISTRIBUTION OF WEST NILE VIRUS IN THE TERRITORY OF THE EUROPEAN PART OF RUSSIA; THE RESULTS OF SEROEPIDEMIOLOGICAL RESEARCH. COMMUNICATION 2: CENTRAL, PRIVOLZHSKY AND NORTH-WESTERN FEDERAL DISTRICTS

Sera of 3951 inhabitants of Central, Privolzhsky and Northwest federal districts of Russia were examined with the use of ELISA-IgG and neutralization test. Antibodies to West Nile virus (WN) were detected in the sera of residents of Voronezh (1,6% of cases), Tula (1,5%), Tambov (0,7%) and Lipetsk(0,6%) regions. Two positive samples have been detected in residents of Moscow and Moscow region, which were possibly infected, during theirs travel to endemic for WN fever regions. All sera obtained from Kaluga, Ryazan, Tver, Vologda, Ulyanovsk regions and The Republic of Tatarstan were negative. Our data, in combination with the morbidity rate of WN fever indicate on epidemiological activity of foci of this infection in the South, the North Caucasus, Privolzhsky (Saratovskaya region) and Central (the forest-steppe zone and Tula region) districts. The northern border of circulation of WN virus probably dispose of the latitude of the Tula region.

THE STUDYOF THE АREA OF DISTRIBUTION OF WEST NILE VIRUS IN THE TERRITORY OF THE EUROPEAN PART OF RUSSIA; THE RESULTS OF SEROEPIDEMIOLOGICAL RESEARCH. COMMUNICATION 2: CENTRAL, PRIVOLZHSKY AND NORTH-WESTERN FEDERAL DISTRICTS

Sera of 3951 inhabitants of Central, Privolzhsky and Northwest federal districts of Russia were examined with the use of ELISA-IgG and neutralization test. Antibodies to West Nile virus (WN) were detected in the sera of residents of Voronezh (1,6% of cases), Tula (1,5%), Tambov (0,7%) and Lipetsk(0,6%) regions. Two positive samples have been detected in residents of Moscow and Moscow region, which were possibly infected, during theirs travel to endemic for WN fever regions. All sera obtained from Kaluga, Ryazan, Tver, Vologda, Ulyanovsk regions and The Republic of Tatarstan were negative. Our data, in combination with the morbidity rate of WN fever indicate on epidemiological activity of foci of this infection in the South, the North Caucasus, Privolzhsky (Saratovskaya region) and Central (the forest-steppe zone and Tula region) districts. The northern border of circulation of WN virus probably dispose of the latitude of the Tula region.

Влияние новых технологий и человеческого капитала на вклад новых укладов в экономику регионов Северо-Западного федерального округа

Econometric impact assessments of new technologies and human capital on a contribution of new technological ways to per capita GDP in regions of Northwest Federal District of Russia are received. Coefficients of elasticity of a contribution of new ways to per capita GDP on use of the new technologies estimated by armament the work equity new fixed assets and for use of the human capital estimated by a share of busy workers with the higher education are estimated. The use of new technologies is the most effective in St. Petersburg, in the Murmansk, Leningrad regions and in the Komi Republic. Efficiency use of new technologies in the Pskov region is the lowest. The human capital is most effectively in the Komi Republic, the Murmansk and Leningrad regions. Efficiency use of a human capital in the Pskov region is the lowest.

CHARACTERIZATION OF MYCOBACTERIUM TUBERCULOSIS STRAINS (A 15-YEAR SURVEY IN LENINGRAD REGION, RUSSIA)

In the late 90-ies of XX century in Russia there was an exacerbation of the epidemic situation of tuberculosis (TB) and “explosive” increase in pathogen drug resistances. Regardless of lower incidence of pulmonary TB in recent years, the number of cases caused by multidrug-resistant (MDR) mycobacteria was increasing due to a reduction in the effectiveness of treatment. Among the 11 subjects of the North-West Federal District the Leningrad Region is leading in the number of ineffective chemotherapy outcomes in newly diagnosed bacteriologically confirmed TB cases. A specific feature of the current epidemic situation in the Leningrad Region is the prevalence (74.1% in 2014) of MDR strains among previously treated patients with pulmonary TB. The aim of the research was a comparative genotypic characterization of Mycobacterium tuberculosis strains, isolated from patients with chronic pulmonary tuberculosis in the Leningrad Region in 1999–2004 and 2010–2014. As defined by spoligotyping, the Beijing family genotype was prevailing among M. tuberculosis strains of previously treated patients from Leningrad region (76.5% in 2010–2014 versus 56.3% in 1999–2004). The proportion of other genotypes strains — LAM and T decreased from 16.7 and 12.5% to 10.3 and 2.9%, respectively. The proportion of multi-drug resistance in the studied subpopulations of the Beijing genotype strains remained virtually constant (86.5 and 88.9%). The extensive drug resistance was not observed among MDR Beijing strains in 1999–2004, whereas in 2010–2014 it reached 33.3%. MIRU-VNTR-typing (12 loci) of 68 M. tuberculosis strains revealed 20 profiles; of these, five were presented by clusters MIT1, MIT46, MIT16, MIT17, MIT571, comprising two or more strains. The largest clusters MIT16 (223325153533) and MIT17 (223325173533) included 25 (48.1%) and 21 (40.4%) apparently highly transmissible Beijing genotype strains. Previously, clinical significance and mainly epidemic pathways for MDR M. tuberculosis Beijing strains belonging to these MIRU-VNTR-types were proved in a number of Russian regions. These findings require in-depth analysis of the situation in the region studied.

Long-Term Trends of Air Temperature Changes in Industrial and Economic Centres of North-Western and Central Federal Districts of Russia and Their Causes

Carried out the review and analysis of long-term variability of mean annual and mean during winter temperature in 13 major administrative and industrial centers of the North-West and Central federal district – Murmansk, Arkhangelsk, Petrozavodsk, St. Petersburg, Pskov, Novgorod, Kaliningrad, Moscow, Smolensk, Tambov, Kostroma, Kursk and Voronezh. On the basis of the method of cluster analysis identified the major regional characteristics variability in air temperature. An assessment of the correlation between the dynamics of the 4 values of climatic indices of atmospheric circulation over the North Atlantic – NAO (North Atlantic Oscillation) and long-term changes in air temperature. Identified and analyzed interannual trends cooling trend over the winter period. Presented a preliminary assessment of the intensity of the impact of changes in temperature conditions on industry and the economy of the North-West and central federal districts in relation to a possible cooling.

Proteomic Profile of Tears for the Diagnosis of Uveitis Associated with Juvenile Idiopathic Arthritis: Setting Targets to Achieve Results

The paper presents epidemiologic and pathophysiological aspects of the problem statement for early recognition of Uveitis (Uv) associated with Juvenile Idiopathic Arthritis (JIA) in terms of the proteomic profile of tears as well as the results of an attempt to solve this problem by means of the Tandem Mass-Spectrometry (TMS). The solution of this problem is of the highest relevance due to revolutionary changes in treatment strategies after introducing highly effective biologics. Content analysis of literature reviews reveals the following: 1. the incidence of JIA-Uv in the Northwest Federal District of Russian Federation averages 0.5-0.7 per 100 000 of children with the prevalence being ten-fold higher than incidence, 2. without Methotrexate treatment 4-7 years after the diagnosis of JIA-Uv cataract is revealed in 35-40% of children and in 5% – glaucoma as well, 3. even with Methotrexate in 28-40% of children the complications of JIA-Uv inevitably will be revealed with blurred vision in 10-36% of children, 4. timely diagnosis of JIA-Uv and adequate treatment reduce the risk of complications by 4% per year, 5. current medical care system reveals in one third of children already the complications of JIA-Uv. Revelation in tears of the motif mode for protein interaction network, triggering mobilization/inhibition of cells which moderate Uv would contradict the traditional point of view on existing natural anatomic and physiologic barriers, isolating the intraocular space, but however seems to be possible since JIA is a systemic disease and Uv leads to damage of the blood-retinal barriers. To reveal protein biomarkers of JIA-Uv tears of 31 children aged 2-17 years were studied: 17 – chronic JIA-Uv, 4 – JIA without Uv, 4 – idiopathic Uv, 3 – systemic vasculitis, 3 – healthy children. We used the current clinical guidelines and standards to diagnose the pathology and TMS with hierarchical clustering methodology for protein identification: nano C18 column attached to Shimadzu nano LC coupled in-line to LTQ Orbitrap XL tandem mass spectrometer, data-dependent 4-event scan method, a survey FT-MS parent scan followed by sequential data dependent FT-MS/MS scans on the three most abundant peptide ions. Proteins were identified from the mass spectra results with Proteome Discoverer 1.2 software for protein database search using the International Protein Index (IPI) and Human Protein Database. Quantification was conducted using SIEVE 2.0 after normalization to albumin keeping in mind the validity of proportional change of its concentration after stimulation of lacri-mation. Data from SIEVE were exported to IPA (Ingenuity Pathway Analysis) for filtering. The extracellular proteins selected in Ingenuity were further analyzed for disease relation and networks formation. TMS revealed more than 3000 proteins in tears and 300 of them have been considered to be the first row candidates to be biomarkers of JIA-Uv. The top two proteins, lactoferrin and lipocalin were upregulated over ten-fold in children with Uv. Pathway analysis placed these proteins into the inflammation-related IL-1 and TNF-α related networks which also included proteins involved in the development of endothelial dysfunction, inflammation and retinopathy. In addition, IL-23, which was previously linked to Uveitis, was found to be upregulated. Taken together, our proof-of-principle study presents a novel and yet untested approach for detection of early biomarkers of Uveitis and identified several candidate proteins.

Definition of the Level of Budget Balance in the Large and Medium Cities of the North-West Federal District by Cluster Analysis Methods

Definition of the Level of Budget Balance in the Large and Medium Cities of the North-West Federal District by Cluster Analysis Methods

Взгляды населения Северо-Западного федерального округа на проблему социальной уязвимости

Взгляды населения Северо-Западного федерального округа на проблему социальной уязвимости

Cities of North-West Federal District: the state of urban development sector and its main challenges

This article analyzes the compliance of planned and actual results of the implementation of the first phase of territorial planning documents of towns, medium and big cities in the North-West Federal District of Russia. Particular attention is paid to the deformation of forecasting scenario for prospective population in researched cities and to identification of factors that contributed to this deformation. The authors propose a variant of preparation of territorial planning documents in a search for effective tools for urban development of the North-West Federal District of Russia.

Antibacterial resistance of Enterococcus spp. isolated from commercial poultry of the Russian Federation farms in 2013–2016, and identification of vancomycin resistance genes

Rationale: Enterococci are the leading cause of a number of nosocomial and community-acquired human diseases. In the last decade, these pathogens are becoming resistant to antibacterials, including vancomycin. Multidrug-resistant enterococci have been also isolated from agricultural animals in many countries worldwide, which raises concern of scientists because of possible horizontal transfer of resistance genes. Aim : To assess antibacterial sensitivity of Enterococcus spp. isolates collected from the poultry in the Russian Federation from 2013 to 2016, and to identify vancomycin-resistance genes in their genomes. Materials and methods : Eighty-seven enterococci isolates belonging to E. faecalis (n = 47, 54%), E. faecium (n = 25, 28.7%) and other species (n = 15, 17.2%) were collected from clinical samples of 297 heads of poultry (liver, lungs, heart, spleen, contents of the nasal and sinus cavities) from 17 poultry farms of the Northwest, Central, Volga, Ural and Southern Federal districts of the Russian Federation. Sensitivity of enterococci to antibacterials was determined by disk-diffusion and broth microdilution methods. Vancomycin resistance genes van was detected by polymerase chain reaction with specific primers. Results : Most enterococci isolates were resistant to erythromycin (74/87, 85.1%), gentamicin (70/87, 80.5%), ceftriaxone (61/87, 70.1%), ciprofloxacin (56/87, 64.4%), tetracycline (57/87, 65.5%), and rifampicin (48/87, 55.2%), fewer ones to trimethoprim (38/87, 43.7%), ampicillin (28/87, 32.2%), linezolid (15/87, 17.2%) and chloramphenicol (5/87, 5.7%). The vanC type genes ( vanC1 and vanC2/3 ) were identified in 10 isolates. Vancomycin minimal inhibitory concentrations for these isolates were 2 to 8 mg/L. E. faecium with vanC1 gene was isolated from poultry probably for the first time ever. Conclusion : Commercial poultry in the Russian poultry farms is an important reservoir and source of antibiotic-resistant enterococci populations, including enterococci carrying vanC1 and vanC2/3 vancomycin resistance genes.

MALIGNANT TUMORS OF THE COLON IN BELARUS AND NORTHWEST FEDERAL DISTRICT OF THE RUSSIAN FEDERATION

Background: Colon cancer (CC) refers to a group of malignant tumors (MT) with a high rate of morbidity increase. In Russia, only from 2000 to 2014 the standardized incidence rate has increased from 12.9 to 16.6 0/0000, or by 28.7% among males, and from 10.8 to 13.10/0000, or by 21.9 % among females. In the Republic of Belarus (RB) the level of CC incidence has increased from 12.0 to 18.0 0/0000 (by 50%) among males and from 9.0 to 13.40/0000 (by 44.4%) among females. In the City of Minsk the level of CC incidence was highest in 2000 and 2014 and has increased by 33.5%, while in St. Petersburg it was lower than in a number of regions of the North-West Federal District of the Russian Federation (NWFD RF) and has decreased by 8.8% for 15 years. Purpose of the study: To present a comparative evaluation of the main analytical rates of CC morbidity, its mortality and the state of contemporary diagnosis in RB and NWFD RF. Materials and methods: The basis of this work consisted of materials of population-based cancer registries databases of RB and NWFD RF. Also there were used published data to compare the basic parameters. For the estimation of the rates there were used the traditional methods. Standardized rates were estimated on the basis of the world standard population structure. Cartograms were prepared on the basis of the methodology of geographic information systems (GIS). Analysis of obtained data: There was performed a precise analysis of population-based data on CC, including particularly the 4th sign of ICD-10 and identified a number of patterns of CC incidence at present stage. Conclusion: CC incidence increases in Russia, North-West Federal District of the Russian Federation and in Republic of Belarus. Registering rates and the state of cancer control have improved at all comparable administrative territories. It primarily concerns such parameters as morphological verification level, early diagnosis, one-year lethality and others. Comparative monitoring and a study of experience in various administrative territories and countries with the best rates could be useful for planning effective anti-cancer programs.

Деятельность органов государственной власти Северо-Западного федерального округа по обеспечению безопасности информации

Деятельность органов государственной власти Северо-Западного федерального округа по обеспечению безопасности информации

GEOCHEMICAL BARRIERS IN SOLID WASTE LANDFILLS OF THE NORTHWEST FEDERAL DISTRICT IN ACCORDANCE WITH ENGINEERING SURVEY RESULTS AND MONITORING DATA

The results of the authors’ engineering surveys and monitoring investigations in solid waste landfills (SWL) of the Northwest Federal District of Russia make it possible to conclude that a colmated watertight barrier and a gley geochemical barrier are formed in any subsoils as a result of the influence of leachate. The authors revealed the presence of real assimilative capacities of SWL ecosystems. Special studies of this phenomenon and of its ecological features can expand options of ground areas for landfills, reduce the cost of engineering survey and construction, reduce the areas of landfills and their sanitary protection zones, and, thus, result in cost reduction and resources saving. The authors propose to perform a complex of lithochemical studies in the framework of an engineering-environmental survey. This will make it possible to substantiate engineering-environmental solutions for the construction and reclamation of SWL territories more rationally.

Cases inefficient antiretroviral therapy for HIV-1 in children

Aim. Study cases virologic failure ART HIV-1 in children. Materials and methods. The blood plasma samples of 6 patients with HIV infection were used, identified under 1 year of life, from the North-West Federal District of the Russian Federation, received in 2014–2016. Presented in a group of patients were aimed at identifying drug resistance in the virus and correction of ART due to virological failure. In the present study we used genotyping by direct sequencing of the site of the polymerase gene (pol) length of 1285 nt., The gene encoding the protease (PR) length of 465 nt. and a portion of the reverse transcriptase (RT) gene length of 820 nt. Results. In all cases, I was diagnosed with HIV-1 subtype A1, the so-called IDU-A, which is the most common form of HIV-1 in the Russian Federation. Among the obtained isolates of HIV have been identified typical drug resistance mutations to NRTI and NNRTI. Detected multiple natural polymorphic variants from the land of the nucleotide sequences. Thus, all samples show protease mutation M36I, R41K, H69K, and L89M, five samples E35D, four samples I13V. Only one among the surveyed our children with combined variant protease gene mutations L63T + V77I + I93L and reverse transcriptase gene V35I + K166R, despite ongoing therapy and absence of significant drug resistance mutations, according to Stanford University-based data showed high viral load – 2.03×107 copies/ml. The importance of the influence of natural polymorphisms in the drug resistance of the virus is discussed. Conclusion. The high frequency of natural polymorphic variants of the protease and reverse transcriptase genes of the virus in clinical samples submitted. The number of such mutations, apparently does not depend on the number of treatment regimens, but found some correlation with adherence to treatment.

COMPARATIVE ANALYSIS OF MORTALITY FROM EXTERNAL CAUSES IN ST. PETERSBURG, NORTHWEST FEDERAL DISTRICT AND RUSSIAN FEDERATION

The purpose of this study was to evaluate the mortality rate of St. Petersburg population from external causes in 2010–2015 in comparison with similar indicators for the Northwest Federal District and the Russian Federation. Materials and methods. The authors used the following data for analysis: annual long-term monitoring of St. Petersburg trauma services status conducted by coordination and methodological center of trauma and orthopedics; government reporting on mortality; data of Federal State Statistics Service (Rosstat); data of St.Petersburg Statistics Service (Petrostat); data of St. Petersburg Medical Information Analysis Center (MIAС); studies on mortality issues as well as methods of descriptive statistics. Results. From 2003 to 2014 St. Petersburg population mortality rate demonstrated a steady decline as well as generally in Russia. 2015 featured a slight increase in absolute number of deaths per year (+1.2%) in St.Petersburg, while the similar indicator across the Russian Federation was still declining (-5.9%). In 2015 mortality from external causes in St. Petersburg constituted 68 deaths per 100 thousand inhabitants, which is 1.6 times less than in the Northwest federal district (109.6 per 100 thousand inhabitants), and 1.7 times less than in the Russian Federation – 112 per 100 thousand population. In the overall mortality structure of St. Petersburg population the external causes have been consistently occupying third place within recent years. In 2015 the proportion of deaths from external causes in general mortality amounted to 5.7%. Conclusions. According to official statistics since 2000 in St. Petersburg the mortality rate from all the major external causes reduced gradually, as well as in the Northwest federal district and on the whole in Russia. Various national and regional programs that have been rolled out in Russia allowed to reduce by half the mortality of working age population from homicide and from suicide by almost 30% in men and 40% in women. The most reliable evaluation can be made by taking into account a consistent reporting data of overall traffic accidents mortality. In calculation of mortality rate from external causes there is a possibility to underreport injury and poisoning mortality rates described by the following ICD-10 codes: X40-X49, R95-R99, Z57, Z58, Z63, R54.

Current EpidemiologicaL Situation on Tularemia in the Northwestern Federal District of Russia

Relevance. In Russia every year are registred 100 or more cases of tularemia, with about 70% of them in the Central, Northwest and Siberian federal districts. Goal. Assessment of the current epidemiological situation on tularemia in the North-West Federal district (NWFD). Materials and methods. By means of a MapInfo Professional-10,5 GIS-package information on selection of cultures of the activator of a tularemia and the recorded incidence was transformed to the database on the basis of which GIS layers were created. Definition of geographical coordinates of places of isolation of cultures of a tulyaremiyny microbe from biological objects in the territory of the NWFD is carried out by means of the GoogleEarth program. Results. In 2001 - 2015 in NWFD incidence observed in all regions of the district, except Novgorod and Pskov regions. But the analysis of incidence of a tularemia allowed to reveal the sick people who infected in the territory of these regions that means there regions is endemic of tularemia. There remains a strong tendency to increase the incidence of tularemia urban population.The lack of permanent monitoring of natural eyes of tularemia in some regions of the district, does not allow to trace the development of epizootic process and to assess the intensity and magnitude of epizootics. As a result, activation of natural foci of tularemia is not noted, which increases the risk of human infection in these areas. Conclusions. Insufficient or complete lack of vaccination of people against tularemia living in areas enzootic for this infection may lead to complication of the epidemiological situation.