Abstract

Sera of 3951 inhabitants of Central, Privolzhsky and Northwest federal districts of Russia were examined with the use of ELISA-IgG and neutralization test. Antibodies to West Nile virus (WN) were detected in the sera of residents of Voronezh (1,6% of cases), Tula (1,5%), Tambov (0,7%) and Lipetsk(0,6%) regions. Two positive samples have been detected in residents of Moscow and Moscow region, which were possibly infected, during theirs travel to endemic for WN fever regions. All sera obtained from Kaluga, Ryazan, Tver, Vologda, Ulyanovsk regions and The Republic of Tatarstan were negative. Our data, in combination with the morbidity rate of WN fever indicate on epidemiological activity of foci of this infection in the South, the North Caucasus, Privolzhsky (Saratovskaya region) and Central (the forest-steppe zone and Tula region) districts. The northern border of circulation of WN virus probably dispose of the latitude of the Tula region.

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