Non-solvent Induced Phase Separation Research Articles

In-situ generation of anti-fouling TpPa/PVDF membranes showing excellent photocatalytic degradation and self-cleaning for dyes in water

Covalent organic frameworks (COFs) have been widely studied in membrane separation technology due to their high porosity, high specific surface area, and tunable pore size. However, COF particles tend to aggregate in blend membranes. In this study, in-situ generation of 2,4,6-Triformylphloroglucinol p-Phenylenediamine (TpPa) was carried out in Polyvinylidene fluoride/N,N-dimethylacetamide (PVDF/DMAc), followed by nonsolvent-induced phase separation (NIPS) method to obtain TpPa/PVDF membranes. The introduction of hydrophilic TpPa resulted in improved hydrophilicity and increased roughness of the membrane. During the filtration of dyes including Methylene Blue, Congo Red, and Eriochrome Black T, the TpPa/PVDF membrane exhibited high rejection rates (>90 %) and improved permeation flux (6–8 times of the original PVDF membrane). Investigation of its photocatalytic ability revealed that the TpPa/PVDF membrane exhibited excellent photocatalytic degradation of dyes, making it suitable for self-cleaning of fouled membranes and allowing for multiple reuse (up to 8 times). In the 6-cycle filtrations of Bovine Serum Albumin (BSA) and Humic Acid (HA), the membrane showed not only high rejection and permeation but also superior flux recovery rate (FRR), indicating good anti-fouling ability. This study has achieved efficient treatment of dye wastewater through membrane separation technology and has provided a novel anti-fouling COFs-modified membrane with photocatalytic self-cleaning ability.

Waste treats waste: Facile fabrication of porous adsorbents from recycled PET and sodium alginate for efficient dye removal

Dye-contaminated water and waste plastic both pose enormous threats to human health and the ecological environment, and simultaneously solving these two issues in a sustainable and resource-saving way is highly important. In this work, a sodium alginate-polyethylene terephthalate-sodium alginate (SA@PET) composite adsorbent for efficient dye removal is fabricated using wasted PET bottle and marine plant-based SA via simple and energy-efficient nonsolvent-induced phase separation (NIPS) method. Benefiting from its porous structure and the abundant binding sites, SA@PET shows an excellent methylene blue (MB) adsorption capacity of 1081 mg g−1. The Redlich–Peterson model more accurately describes the adsorption behavior, suggesting multiple adsorption mechanisms. In addition to the electrostatic attractions of SA to MB, polar interactions between the PET matrix and MB are also identified as adsorption mechanisms. It is worth mentioning that SA@PET could be recycled 7 times without a serious decrease in performance, and the trifluoroacetic acid-dichloromethane solvent involved in the NIPS process has the possibility of reuse and stepwise recovery. Finally, the discarded adsorbent could be completely degraded under mild conditions. This work provides not only a composite adsorbent with excellent cationic dye removal performance for wastewater treatment, but also an upcycling strategy for waste PET.

Insights into the preparation of zein nanoparticles by continuous membrane nanoprecipitation

Nanoparticles (NPs) preparation is limited to an exclusive use in batch processes and small-scale formulations. The use of membranes as high-performance micromixers is expected to open new scenarios to overcome limitations of conventional nanoprecipitation system such as stirred tank (ST) nanoprecipitation. The ability of the porous membrane to add uniformly one phase to another and govern their mixing at the membrane interface seems to be an important parameter for obtaining uniform NPs. Inorganic membranes (pore size of 1 μm) were used to carry out membrane nanoprecipitation (MN) to form Zein nanoparticles (ZNPs) at pores level by non-solvent induced phase separation. A systematic study of the preparation of ZNPs in the ST and MN systems was carried out to establish the Ouzo diagram. The influence of zein concentration and solvent to non-solvent ratio on the size and size distribution of ZNPs was also investigated. A wider stable Ouzo zone was obtained with MN than with the ST process. ZNPs size increased from 100 nm up to 700 nm, while maintaining low polydispersity index (PDI < 0.2). The results demonstrate the suitability of MN for the continuous production of ZNPs and open the possibility of scaling up the nanoprecipitation process.

Reversibly Cross-Linked Isoporous Membranes Fabricated by the Recyclable Block Copolymer with Pendent Dithiolane Groups.

The reversible formation and cleavage of disulfide bonds under physical/chemical stimuli make it a valuable motif in constructing dynamically cross-linked materials. In the present work, the block copolymer bearing pendent dithiolanes was synthesized and fabricated into isoporous membranes by the combination of self-assembly and nonsolvent-induced phase separation strategy. The cross-linking within the membrane was realized by the thiol-initiated ring-opening cascades of cyclic disulfides. Successful formation of disulfide bond networks within the isoporous membranes was proved by the Raman spectra, UV-vis diffuse reflectance spectroscopy, differential scanning calorimetry, and rheological analysis. The cross-linking in membranes was further demonstrated by the notably improved toughness and obviously enhanced swelling resistance to acid/alkaline solution as well as organic solvents. Importantly, the cross-linked isoporous membranes were fully dissolvable in solution containing dithiothreitol, which enabled the complete cleavage of disulfide bonds and successful recovery of the block copolymer that was able to be repeatedly fabricated into isoporous membranes with pore sizes identical to membranes prepared from the freshly synthesized copolymer. Our results indicate that dynamically cross-linked isoporous membranes with improved durability and good recyclability can be custom-made by simply incorporating active dithiolane moieties into self-assembling block copolymers.

Development of novel high anti-pollution polyamide/polysulfate disk tubular reverse osmosis membrane modules and their application in simulated space bathing wastewater

Water is a precious resource in space stations, and wastewater recycling is necessary to meet the needs of astronauts. In that respect, applying the high anti-pollution disk tubular reverse osmosis (DTRO) technique is a reliable way to remove pollutes from wastewater. Thin film composite (TFC) membrane treatment is the most frequently employed solution for purifying wastewater in industry; however, the intrinsic weaknesses of polymer membrane substrates, e.g., poor mechanical property, foulant adsorption and low resistance to acidic/basic conditions, greatly hamper their applications. In this study, the novel polysulfate (PSE) membrane substrates were prepared via non-solvent induced phase separation (NIPS) method. The microstructure and performance of PSE membrane substrates were comprehensively investigated at varying polymer concentration and nanoparticle types. The results showed that adding nanosilver to the support layer significantly enhanced the TFC- PSE/Ag membrane performance (up to 57 %) and tensile strength (by 4.57 ± 0.13). According to computational fluid dynamics (CFD) simulations, the optimized geometric design of deflectors would have noticeably improved the flow field distribution and strength, which was consistent with experimental data. The DTRO modules enabled the effective management of wastewater using simulated space bathing wastewater. The effluent met the water reuse criteria in terms of COD concentration, NH3-N concentration, conductivity and turbidity whose respective values were 15 mg/L, 0.21 mg/L, 60 μS/cm, and 0.9 NTU. The proposed DTRO modules own antifouling and acid/alkaline-resistance, indicating their remarkable application potential in the large-scale recovery of bathing wastewater from the earth or space station.

Asymmetric copolyimide membranes fabricated by nonsolvent-induced phase separation for He/CH4 and He/N2 separation

Asymmetric copolyimide membranes fabricated by nonsolvent-induced phase separation for He/CH4 and He/N2 separation

Green photocatalytic mixed matrix membranes for simultaneous arsenic photo-oxidation and water recovery via membrane distillation

This work proposes an innovative integration of Membrane Distillation (MD) and photo-oxidation for a continuous recovery of water from arsenic (As) contaminated solutions coupled with the oxidation of arsenite (As(III)) into arsenate (As(V)). Polyvinylidene fluoride (PVDF) mixed matrix membranes (MMMs) containing titanium dioxide nanoparticles (TiO2 NPs) as photocatalyst were developed. A systematic study elucidated the effect of TiO2 NPs on membranes’ morphology prepared via non-solvent-induced phase separation (NIPS) using triethyl phosphate (TEP) as a green solvent for PVDF solubilization. Vacuum membrane distillation (VMD) tests carried out by irradiating the MMMs with ultraviolet (UV) radiation demonstrated the possibility of recovering up to 80 % of the water from As-contaminated synthetic and real multi-ions aqueous solutions from Sila Massif (Italy). The distillate was recovered at a rate of 6.9–7.2 kg·m−2·h−1 (feed inlet temperature of 60 °C), while the presence of 7 wt% of TiO2 in PVDF membranes enabled the photo-oxidation of 95 % of the As(III) to As(V) at a first order kinetic constant of 0.0106 min−1. After 5 cycles of As-remediation experiments, post-hoc mechanical testing on the membrane suggested the emergence of polymer embrittlement induced by UV radiation (total irradiation time of 7.5 h), highlighting the urgent need for developing photocatalytic membranes with long-term stability.Overall, this study elucidates at laboratory scale the performance of a coupled and continuous Membrane Distillation (MD) and photo-oxidation system for arsenic (As) remediation, employing microporous hydrophobic green membranes doped with a photocatalyst.

The Formation Process and Mechanism of the 3D Porous Network on the Sulfonated PEEK Surface.

A three-dimensional (3D) porous network can be prepared on the PEEK surface by sulfonation with enhanced osseointegration and antibacterial properties. However, few studies have been conducted on the formation mechanism of a 3D porous network. In this work, the surface and cross-sectional morphologies, chemical compositions, functional groups, surface wettability, and crystalline states of sulfonated PEEK were investigated at different sulfonation times and coagulant concentrations. The results show that the number of nodular structures and broken fibers on the sulfonated PEEK surface as well as the size of macrovoids in the cross sections increase with increasing sulfonation times when water is used as a coagulant. In contrast, dilute sulfuric acid as a coagulant can inhibit the formation of surface porous structures and macrovoids in the cross sections. Moreover, all of the sulfonated PEEK samples have the same chemical compositions but exhibit better hydrophilicity as the number of microsized pores decreases. It is proposed that non-solvent-induced phase separation (NIPS) occurs during the sulfonation process, and the formation mechanism of surface and cross-sectional morphologies is discussed. Furthermore, it is assumed that the air is trapped in the microsized pores, leaving the surface of the 3D porous network in the Cassie-wetting state. All of these preliminary results throw light on the nature of the sulfonation process and may guide further modification of the structures of sulfonated PEEK.

Effect of thermal processing conditions on the structure and properties of porous PENK/PVDF composite films and its application as lithium-ions separators

By developing high-performance lithium-ion battery technology, the demands on the design of separator modification have increased. However, battery performance and safety are limited by conventional polyolefin separators' poor thermal resistance and electrolyte wettability. Biphenyl-type poly (arylene ether nitrile ketone) (BP-PENK) is synthesized. PENK polymers are a class of poly (aryl ether) with excellent properties of both Poly (aryl ether nitrile) (PEN) and Poly (ether ketone) (PEEK). The BP-PENK/PVDF composite film is further processed by non-solvent induced phase separation (NIPS), and the impact of annealing temperatures on the thermal resistance and crystalline phase structure of composite separators has been studied. The composite separator owns enhanced ionic conductivity, excellent electrolyte wettability, and superior thermal durability. The cell equipped with the composite separator has a discharge-specific capacity of 146.5 mAh·g−1 and a capacity retention rate of 86.64 %. In this way, A novel approach to producing lithium-ion battery separators that possess outstanding electrochemical properties and high thermal durability is provided.

Investigating microstructure evolution in block copolymer membranes.

Block copolymer self-assembly in conjunction with nonsolvent-induced phase separation (SNIPS) has been increasingly leveraged to fabricate integral-asymmetric membranes. The large number of formulation and processing parameters associated with SNIPS, however, has prevented the reliable construction of high performance membranes. In this study, we apply dynamical self-consistent field theory to model the SNIPS process and investigate the effect of various parameters on the membrane morphology: solvent selectivity, nonsolvent selectivity, initial film composition, and glass transition composition. We examine how solvent selectivity and concentration of polymers in the film impact the structure of micelles that connect to form the membrane matrix. In particular, we find that preserving the order in the surface layer and forming a connection between the supporting and surface layer are nontrivial and sensitive to each parameter studied. The effect of each parameter is discussed, and suggestions are made for successfully fabricating viable block copolymer membranes.

Preparation and performance of magnetic carbon nanotubes modified PVC substrate composite nanofiltration membranes

Polyamide (PA)/ferroferric oxide/oxidized multi-walled carbon nanotubes (Fe3O4/o-MWCNTs)/polyvinyl chloride (PVC) composite nanofiltration (NF) membranes were prepared by the interfacial polymerization (IP) process with the Fe3O4/o-MWCNTs/PVC porous membrane as the substrate membrane, which was prepared by the magnetic field assisted non-solvent induced phase separation method (NIPS) with the synthesized superparamagnetic Fe3O4/o-MWCNTs nanoparticles (NPs) as the additives of the functional intermediate layer integrated with the substrate. The effects of the magnetic carbon nanotubes modified PVC porous substrate membrane on the surface chargeability, PA layer thickness, mechanical properties, pressure resistance and permeability of the composite NF membranes were investigated, and the comprehensive performance of composite NF membranes was enhanced. The results indicated that the porosity and hydrophilicity of the Fe3O4/o-MWCNTs/PVC porous substrate membrane were improved by the migration of magnetic Fe3O4/o-MWCNTs NPs to the upper edge of the substrate membrane and uniform enrichment under magnetic field induction, which further affected the structure and properties of the PA/Fe3O4/o-MWCNTs/PVC composite NF membrane. The prepared NF membrane presented smaller roughness, thinner PA layer, larger pore size, with excellent mechanical properties and better pressure resistance. Meanwhile, the PA/Fe3O4/o-MWCNTs/PVC composite NF membrane presented excellent divalent salt rejection, with the rejection of MgSO4 and Na2SO4 maintaining more than 95.2% and 93.4%, respectively, while the permeation flux could reach 35.4 L·m−2·h−1. In summary, the modification of the substrate integrated with the functional intermediate layer had certain enlightening significance for the preparation of the NF membrane with excellent comprehensive performance.

Investigating the Role of a P(VDF−TrFE) Ferroelectric Separator in Li‐Metal Pouch Cells using Electrochemical Impedance Spectroscopy

AbstractThis study explores the efficacy of employing P(VDF−TrFE), a ferroelectric copolymer, to mitigate the formation of dead lithium in Li‐metal anodes when paired with carbonate electrolytes. Employing non‐solvent induced phase separation (NIPS), self‐standing membranes and coatings on polypropylene (PP) separators were prepared, both demonstrating a homogenous cellular pore structure and excellent ionic conductivity. Rigorous evaluation in pouch cell formats, featuring a thin Li‐metal anode (50 μm), a high‐loading NMC532 cathode (3 mAhcm−2), and a carbonate electrolyte, reveals the superior performance of cells with P(VDF−TrFE)‐coated PP separators. Notably, these cells exhibit slower and more consistent capacity fading, as well as the weakest increase in impedance, as evidenced by Electrochemical Impedance Spectroscopy (EIS) investigations. This work underscores the promising role of P(VDF−TrFE) as a key material for addressing challenges associated with dead lithium, offering valuable insights for advancing Li‐metal battery technologies in practical applications.

Influence of citric acid concentrations on the porosity and performance of cellulose acetate-based porous membranes: A comprehensive study

This study investigates the influence of citric acid concentration on the fabrication of porous cellulose acetate (CA) membranes using the Non-Solvent Induced Phase Separation (NIPS) method. A notable aspect is the precise control over membrane properties, particularly pore size and porosity, achieved solely through the adjustment of citric acid concentration, serving as the additive. Higher concentrations of citric acid increase pore size by rendering polymer chains more pliable, whereas lower concentrations lead to smaller, denser pores due to improved dispersion in the CA matrix and altered water interactions during phase separation. A decrease in porosity and Gurley values with reducing citric acid concentrations (from 5 × 10−2 to 1 × 10−3 M ratios) indicates less plasticization of CA chains. However, at very low concentrations (1 × 10−4 and 1 × 10−5), porosity increases, despite the presence of smaller pores, and Gurley values approach those of pure CA in terms of gas permeability. Fourier Transform Infrared (FT-IR) spectroscopy confirms the presence of citric acid and its interaction with carbonyl groups, consistent with the pore size observations from Scanning Electron Microscopy (SEM). Spectral data deconvolution reveals weakened carbonyl bonds due to the reduced presence of citric acid, correlating with the smaller pores observed in SEM. Thermal Gravimetric Analysis (TGA) demonstrates that composite membranes are more thermally stable than pure CA, attributed to the citric acid-induced crosslinking within the polymer chains. Stability increases with decreasing citric acid concentration, with some anomalies at the lowest levels. In conclusion, this study highlights the capability of adjusting citric acid concentration to tailor membrane properties, offering valuable insights for the creation of porous materials across diverse industrial applications.

Fabrication of Polysulfone - Zeolite Nanocomposite Membrane for Water and Wastewater Treatment Applications

Freshwater is essential in sustaining human life on the planet and the demand for potable water has increased for the past years due to population growth and modernization. However, the natural resources of water have become polluted/contaminated due to industrialization and other human activities. The development of membrane technology, especially with the creation of nanocomposite materials, provides a solution to treat polluted or contaminated water through various separation processes resulting in the production of clean water fit for human consumption. In this study, polysulfone was added with zeolite nanoparticles to fabricate nanocomposite membranes via non-solvent induced phase separation (NIPS) method to enhance the hydrophilicity and mechanical strength of the membrane suitable for water and wastewater applications. The nanozeolite was added in varying concentrations; 1% 5% and 10% and the fabricated membranes were characterized via Contact Angle Goniometer, universal testing machine (UTM) and scanning electron microscopy (SEM) to determine the contact angle, tensile strength, and surface morphology, respectively. Based on the characterization data, the 1% concentration showed the highest tensile strength and the lowest contact angle measurement. The 1% nanozeolite concentration is the optimum membrane formulation due to the enhanced hydrophilicity and mechanical strength of the material.

Upcycled PVC support layer from waste PVC pipe for thin film composite nanofiltration membranes

Thin-film-composite (TFC) nanofiltration membranes represent the pinnacle of membrane technology in water treatment and desalination. These membranes typically consist of a polyamide (PA) selective layer and a membrane support layer, often constructed from commercially available materials like polyethersulfone (PES). However, there exists an alternative approach that involves the use of different polymers, preferably upcycled waste polymers, as a viable support layer for TFC membranes. Successfully implementing the upcycling of waste plastics into high-value support membranes can make a significant contribution to addressing the issue of plastic waste pollution. One of the primary challenges associated with utilizing upcycled polymers as support layers is the potential impact on the polyamide selective layer of TFC membranes, subsequently affecting their performance in terms of permeability, rejection, and antifouling properties. In this study, we demonstrate the successful fabrication of TFC membranes with a support layer crafted from upcycled waste PVC pipe. We conducted a comprehensive investigation into the effects of upcycled PVC on the structural and physicochemical properties of the polyamide layer. The ultrafiltration (UF) support membranes were fabricated from waste PVC pipe via the nonsolvent induced phase separation (NIPS) method. Subsequently, a polyamide layer was synthesized atop the Upcycled PVC membrane using interfacial polymerization (IP). The physicochemical properties and performance of the TFC membranes with upcycled PVC support layer were compared with membranes with research-grade (RG) PVC and commercial PES support layers. The results unveiled that the TFC membrane with upcycled PVC support layer exhibited higher water permeability (18.2 LMH/bar), in contrast to RG TFC (15.5 LMH/bar) and PES TFC membranes (13.7 LMH/bar). Furthermore, the salt rejection capabilities of the upcycled PVC TFC membrane were competitive and well within an acceptable range.

Enhanced antifouling and separation capabilities of polydopamine@Ce-MOF functionalized PES ultrafiltration membrane

The need for antifouling membranes is substantial due to fouling’s negative impact on the effectiveness and durability of ultrafiltration membranes. In recent times, Metal-Organic Frameworks (MOFs) have emerged as effective additives for crafting ultrafiltration (UF) membranes. However, to harness their benefits and mitigate their drawbacks, a well-considered approach is imperative. In this work, polyethersulfone (PES) UF membranes were tailored with polydopamine (PDA)-modified cerium (Ce)-MOF (PDA@Ce-MOF) to achieve satisfactory antifouling properties and to remove biological macromolecules such as bovine serum albumin (BSA) and humic acid (HA) from wastewater. The non-solvent induced phase separation (NIPS) method was used to simultaneously fabricate the membrane and modify it with different PDA@Ce-MOF concentrations ranging from 0.05 to 0.50 wt.%. Results showed significant improvements on the membrane’s morphology, hydrophilicity, porosity and pore size at 0.10 wt.% loading of PDA@Ce-MOF. The synergistic effect of the PDA and Ce-MOF on the membrane improved the pure water flux (337 L m−2 h−1) and filtration performance in the filtration of Bovine serum albumin (BSA) and humic acid (HA) reporting 145 L m−2 h−1 and 98% rejection, and 164 L m−2 h−1 and 88% rejection; respectively. Further, water-attracting functional moieties of PDA@Ce-MOF hindered the deposition of BSA protein on the membrane surface, resulting in an excellent flux recovery ratio (FRR) of ~87%, alongside mitigated irreversible fouling.

Development of multifunctional membranes via plasma-assisted nonsolvent induced phase separation

Demands on superhydrophobic, self-cleaning and piezoelectric membranes have gained significantly due to their potential to overcome global shortages in clean water and energy. In this study, we have discovered a novel plasma-assisted nonsolvent induced phase separation (PANIPS) method to prepare superhydrophobic, self-cleaning and piezoelectric poly(vinylidene difluoride) (PVDF) membranes without additional chemical modifications or post-treatments. The PANIPS membranes exhibit water contact angles ranging from 151.2° to 166.4° and sliding angles between 6.7° and 29.7°. They also show a high piezoelectric coefficient (d33) of 10.5 pC N−1 and can generate a high output voltage of 10 Vpp. The PANIPS membranes can effectively recover pure water from various waste solutions containing Rose Bengal dye, humic acid, or sodium dodecyl sulfate via direct contact membrane distillation (DCMD). This study may provide valuable insights to fabricate PANIPS membranes and open up new avenues to molecularly design advanced superhydrophobic, self-cleaning, and piezoelectric membranes in the fields of clean water production, motion sensor, and piezoelectric nanogenerator.

Preparation of NaCl Particles Added Polyvinylidene Fluoride Microporous Filter and a Simple Filtration Device

Clean and pollution-free water plays a crucial role in human metabolism and is essential for everyone’s daily life. However, with industrialization, a significant amount of sewage has been produced for many years. Water resources tend to become stressed when the rate of sewage production speed is purified. Many researchers are working on sewage purification to eliminate this hidden danger. It is urgent to find an efficient, high-speed, and environmental way to purify sewage. The objective of this study is to investigate the impact of pore morphology on filtration. In addition, a Polyvinylidene fluoride (PVDF)-microporous filter (MPF) based on non-solvent-induced phase separation (NIPS) and vapor-induced phase separation (VIPS) methods was designed, the morphology and properties of a series of sodium chloride particles (NaCl-ps) added PVDF-MPF was researched, and a simple semi-automatic filtration device based on the character of this PVDF-MPF was manufactured. According to the light transmittance of filtered sewage through PVDF-MPF and NaCl-ps added PVDF-MPF, both PVDF-MPFs can remove particles in sewage. However, after adding NaCl-ps, the purification capacity of PVDF-MPF is higher than that of PVDF-MPF without adding NaCl-ps. The addition of NaCl-ps changes the morphology and improves the sewage purification capacity of PVDF-MPF.

Preparation, Modification, and Application of Ethylene-Chlorotrifluoroethylene Copolymer Membranes.

Ethylene-chlorotrifluoroethylene (ECTFE) was first commercialized by DuPont in 1974. Its unique chemical structure gives it high heat resistance, mechanical strength, and corrosion resistance. But also due to these properties, it is difficult to prepare a membrane from it by the nonsolvent-induced phase separation (NIPS) method. However, it can be prepared as a microfiltration membrane using the thermally induced phase separation (TIPS) method at certain temperatures and with the selection of suitable solvents, and the use of green solvents is receiving increasing attention from researchers. The surface wettability of ECTFE membranes usually needs to be modified before use to strengthen its performance to meet the application requirements, usually by graft modification and surface oxidation techniques. This paper provides an overview of the structure of ECTFE and its preparation and modification methods, as well as recent advances in its application areas and prospects for the future methods of preparing high-performance ECTFE membranes.

Enhancing oil–water emulsion separation using improved styrene–acrylonitrile copolymer membrane: Experimental and thermodynamic study of the impact of solvent mixtures

AbstractThis study investigated the fabrication of styrene–acrylonitrile copolymer (SAN) membrane using the nonsolvent‐induced phase separation (NIPS) method with a combination of solvents, namely N‐methyl‐2‐pyrrolidone (NMP) and dimethylformamide (DMF) and water as the nonsolvent. Since the impact of varying solvent ratios on SAN membrane performance remained unexplored, this study aimed to address this knowledge gap in the context of oil–water emulsion separation. Experimental results demonstrated that employing a solvent mixture, rather than a pure solvent, led to improved membrane performance. The primary objective of this work was to experimentally determine the optimal solvent ratio for enhancing SAN copolymer membrane performance. Additionally, the Flory–Huggins thermodynamic model was applied to investigate the possibility of predicting membrane binodal data. The thermodynamic analysis revealed a strong agreement between calculated and experimental binodal data, with an error of less than 3.8%. Notably, membranes produced with an equal solvent ratio exhibited the most hydrophilic properties, resulting in increased permeability. The permeate flux for distilled water reached 320 L/(m2 h) (LMH), and water contact angle of the membrane was 22°. Furthermore, mechanical resistance increased up to 50%. These results highlight the promising potential of fabricating SAN membrane using solvent mixtures for oil–water emulsion separation.