An innovative type of steel-concrete composite column, named the prestressed stayed circular concrete-filled double skin steel tubular (PS-CCFDSST) column, is introduced in this study, aiming to achieve both structural efficiency and economic advantages. Numerical simulation and theoretical analysis on the axial compressive behaviour of PS-CCFDSST columns were carried out, to understand and reveal their fundamental working mechanisms. Nonlinear finite element analysis (FEA) utilising ABAQUS was performed and validated against collected test data of CCFDSST columns and PS columns. Properly designed PS-CCFDSST columns could gain cost savings of over 30 % while maintaining identical load-bearing capacity as prestressed stayed hollow steel tube (PS-HST) columns with the same steel usage. The effects of initial pretension, nominal steel ratio, hollow ratio, column’s slenderness ratio, relative length of struts, column diameter, strut diameter and cable area on the buckling mode and buckling capacity of PS-CCFDSST columns were evaluated via parametric studies. The stiffness ratio β could be used as an index to comprehensively assess the structural efficiency of PS-CCFDSST columns, and a critical threshold of β = 2 corresponds to the transition between symmetric and anti-symmetric buckling modes. Linear calculation formulae for the theoretical buckling capacity and optimal initial pretension of PS-CCFDSST columns were derived. Finally, practical design equations for predicting the column’s buckling capacity were developed, and recommended values for the actual optimal initial pretension and other primary parameters were provided for PS-CCFDSST columns under axial compression. This study, for the first time, provides the fundamental mechanical behaviour, identification of the critical stiffness ratio for buckling mode transition, and design framework for buckling capacity of the PS-CCFDSST column, which is useful for advancing theoretical exploration and informing engineering practices for this new column type.