Non-syndromic Unilateral Cleft Lip And Palate Research Articles

Midfacial morphology in children with unilateral cleft lip and palate treated by different surgical protocols

The purpose of this study was to compare cranio-facial, particularly midfacial morphology, in two groups of children with complete unilateral cleft lip and palate (UCLP) treated at two different cleft centres (Hannover, Germany and Brussels, Belgium) following different surgical treatment protocols. A total of 62 children (40 males; 22 females) with non-syndromic UCLP were included in this study at approximately the age of 10. The Hannover group comprised 36 children, who had repair of the lip at a mean age of 5.83±1.16 months, followed by repair of the hard and soft palate at a mean age of 29.08±4.68 and 32.25±4.29 months, respectively. The Brussels group consisted of 26 children who underwent surgical treatment according to the Malek protocol: the soft palate was closed at a mean age of 3.04±0.20 months, followed by simultaneous repair of the lip and hard palate at a mean age of 6.15±0.68 months. Midfacial morphology was evaluated by means of cephalometric analysis according to Ross. The children in the Hannover UCLP group did not differ significantly from those in the Brussels group in the anteroposterior dimension of the midface. However, the maxillary plane was significantly more open in the Brussels group due to less posterior vertical maxillary development.