Nonspecific Pericarditis Research Articles

Newer laboratory aids in the differential diagnosis of acute pericarditis: With particular emphasis upon the value of the fibrinogen polymerization test

1. (1) The present report concerns itself with comparative studies of the fibrinogen polymerization test, and several acute phase reactants such as the CRP, ESR, and plasma fibrinogen concentration, and also the ASO titer. These were followed serially in patients with idiopathic, rheumatic and presumably tuberculous pericarditis and also in cases of atypical myocardial infarction. 2. (2) A consistently positive F.P. test indicated the presence, and mirrored the course, of rheumatic and idiopathic pericarditis, while it was negative in tuberculous pericarditis. Of the acute phase reactants only the ESR was abnormal to a comparable degree in all conditions studied. It seems, therefore, that the F.P. test can serve as a valuable aid in the diagnosis of idiopathic pericarditis. 3. (3) In contrast to all nonspecific acute phase reactants the F.P. test appears not to be suppressed by salicylates or steroid therapy but reflects the activity of the disease and thus provides a useful criterion for the efficacy of therapy. 4. (4) The F.P. test appears, furthermore, of value for the differential diagnosis between atypical myocardial infarction and acute non-specific pericarditis, particularly, when used concomitantly with the SGO-transaminase or serum aldolase tests.

Acute pericarditis as the first manifestation of infectious mononucleosis.

Case Reports1 August 1957ACUTE PERICARDITIS AS THE FIRST MANIFESTATION OF INFECTIOUS MONONUCLEOSISDAVID M. ROSEMAN, M.D., RICHARD M. BARRY, M.D.DAVID M. ROSEMAN, M.D.Search for more papers by this author, RICHARD M. BARRY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-2-351 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDespite the publication in recent years of numerous case reports of acute nonspecific pericarditis, little progress has been made in defining its etiology. Clinical manifestations have been adequately reviewed.1, 2, 3 The syndrome, sometimes following an upper respiratory infection, is characterized by anterior chest pain of pericardial origin, often with a pleuritic component which may be influenced by position. Moderate enlargement of the cardiac silhouette is common and is usually attributed to a small pericardial effusion. Pleural effusion may also occur. The electrocardiographic changes follow the typical evolutionary pattern of acute pericarditis.Infectious mononucleosis, on the other hand, is a...Bibliography1. CarmichaelSpragueWymanBland DBHBSMEF: Acute non-specific pericarditis: clinical, laboratory and followup considerations, Circulation 3: 321-331, 1951. CrossrefMedlineGoogle Scholar2. Goyette EM: Acute idiopathic pericarditis, Ann. Int. Med. 39: 1032-1044, 1953. LinkGoogle Scholar3. Krook H: Acute non-specific pericarditis, Acta med. Scandinav. 148: 201-218, 1954. CrossrefMedlineGoogle Scholar4. WechslerRosenblumSills HFAHCT: Infectious mononucleosis: report of an epidemic in an Army post, Ann. Int. Med. 25: 236-265, 1946. LinkGoogle Scholar5. JaffeFieldMaster HLLEAM: Electrocardiogram in infectious mononucleosis, New York State J. Med. 48: 1382-1385, 1948. MedlineGoogle Scholar6. EvansGraybiel WFA: Electrocardiographic evidence of cardiac complications in infectious mononucleosis, Am. J. M. Sc. 211: 220-226, 1946. CrossrefMedlineGoogle Scholar7. CusterSmith RPEB: The pathology of infectious mononucleosis, Blood 3: 830-857, 1948. CrossrefMedlineGoogle Scholar8. Leibowitz S: Infectious mononucleosis, Modern Medical Monographs, 1953, Grune and Stratton, New York, pp. 46-54. Google Scholar9. De FazioMarsico VF: Complicanze cardiache nel corso della mononucleosi infettiva; un caso di pericardite, Progr. med., Napoli 7: 545-550, 1951. MedlineGoogle Scholar10. MillerUricchioPhillips HJFRW: Acute pericarditis associated with infectious mononucleosis, New England J. Med. 249: 136-140, 1953. CrossrefMedlineGoogle Scholar11. SoloffZatuchni LAJ: Infectious mononucleosis associated with symptoms of acute pericarditis, J. A. M. A. 152: 1530-1531, 1953. CrossrefMedlineGoogle Scholar12. Kramer ML, cited by Leibowitz, S.: Infectious mononucleosis, Modern Medical Monographs, 1953, Grune and Stratton, New York, p. 50. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication March 17, 1956.From the Department of Medicine, The New York Hospital-Cornell Medical Center, New York, N. Y.Requests for reprints should be addressed to David M. Roseman, M.D.11 East Sixty-eighth Street, New York 21, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCase 34-1980Mononucleosis infectiosa (Pfeiffer’sches Drüsenfieber)Mononucleosis infectiosa (Pfeiffer’sches Drüsenfieber)Pericarditis due to infectious mononucleosisRelapsing Coxsackie Pericarditis Simulating Myocardial Infarction and Da Costa's SyndromeTreatment of Infectious MononucleosisHAROLD R. SCHUMACHER, WILLIAM A. JACOBSON, CARL R. BEMILLER, M.D.Pericarditis: A ten year surveyMyokarditis und weitere Myokardiopathien 1 August 1957Volume 47, Issue 2Page: 351-356KeywordsElectrocardiographyEtiologyIschemiaPharyngitisPhosphatasesPleural effusionUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 August 1957 PDF downloadLoading ...

Calcification of the pericardium caused by a hitherto unrecognized etiological factor

Calcification of the pericardium has been associated with diseases of varied etiology. However, in the majority of cases the etiological agent remains undefined. The most frequently recognized causes are tuberculosis, rheumatic fever, septic infections, and nonspecific pericarditis. Of lesser incidence are trauma, neoplasm, foreign body, and myocardial infarction. 1–3 Recently, histoplasmosis has been suggested as another agent responsible for calcification of the pericardium. 4 In a recent clinicoroentgenologic study of workers employed in talc mills and mines by one of the authors (M.K.), calcification of the pericardium was observed in three of thirty-seven cases. 5 It is the purpose of this paper (a) to present these three cases with calcification of the pericardium, (b) to establish another etiological agent (inhalation of talc) for pericardial calcification, and (c) to discuss the possible mechanisms responsible for the latter.

ACUTE BENIGN NONSPECIFIC PERICARDITIS WITHOUT A PERICARDIAL FRICTION RUB

Article1 September 1956ACUTE BENIGN NONSPECIFIC PERICARDITIS WITHOUT A PERICARDIAL FRICTION RUBMAXWELL L. GELFAND, M.D., F.A.C.P., LOUIS GOODKIN, M.D.MAXWELL L. GELFAND, M.D., F.A.C.P.Search for more papers by this author, LOUIS GOODKIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-45-3-490 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough acute benign pericarditis has long been known to the medical profession under many different designations, it was not until 1942, when Barnes and Burchell described their 14 cases of acute pericarditis of the nonsuppurative type, that interest in this disease was stimulated.1 Recent years have witnessed an increased number of reports concerning the condition, and most observers have stressed its close resemblance to acute coronary occlusion with myocardial infarction.It is extremely important to differentiate between acute benign pericarditis and myocardial infarction, because the prognosis and treatment of these two conditions are diametrically opposite. The former offers a good...Bibliography1. BarnesBurchell ARHB: Acute pericarditis simulating acute coronary occlusion, Am. Heart J. 23: 247, 1942. CrossrefGoogle Scholar2. Goyett EM: Acute idiopathic pericarditis, Ann. Int. Med. 39: 1032, 1953. LinkGoogle Scholar3. Christian HA: Nearly ten decades of interest in idiopathic pericarditis, Am. Heart J. 42: 645, 1951. CrossrefMedlineGoogle Scholar4. Wolff L: Acute pericarditis with special reference to changes in heart size, New England J. Med. 229 : 423, 1943. CrossrefGoogle Scholar5. Wolff L: Diagnostic implications of pericardial, pleural and pulmonary involvement in cardiovascular disease, New England J. Med. 244: 965, 1951. CrossrefMedlineGoogle Scholar6. FullerQuinlan CCJW: Acute pneumonitis and pericarditis, New England J. Med. 229: 399, 1943. CrossrefGoogle Scholar7. LevyPatterson RLMC: Acute serofibrinous pericarditis of undetermined cause, Am. J. Med. 8: 34, 1950. CrossrefMedlineGoogle Scholar8. WróblewskiLaDue FJS: Serum glutamic oxalacetic transaminase in the detection and evaluation of acute myocardial infarction, Thirty-Sixth Annual Session, Am. Coll. of Phys., Philadelphia, Pa., April 27, 1955. Google Scholar9. TaubenhausBrams MWA: Treatment of acute nonspecific pericarditis with Aureomycin, J. A. M. A. 142: 973, 1950. CrossrefGoogle Scholar10. TomlinLogueHurs CERBJW: Recurrent nature of acute benign pericarditis, J. A. M. A. 149: 1215, 1952. CrossrefMedlineGoogle Scholar11. RosenowCross OFCJ: Acute benign pericarditis, Arch. Int. Med. 87: 795, 1951. CrossrefGoogle Scholar12. KursbanIglauer NJA: Acute nonspecific pericarditis: report of case treated with ACTH (adrenocorticotrophic hormone), Ohio State M. J. 47: 915, 1951. MedlineGoogle Scholar13. NathanDathe ARA: Pericarditis with effusion following infection of the upper respiratory tract, Am. Heart J. 31: 115, 1946. CrossrefMedlineGoogle Scholar14. FinkelsteinKlainer DMJ: Pericarditis associated with primary atypical pneumonia, Am. Heart J. 28: 385, 1944. CrossrefGoogle Scholar15. Willius FA: Clinic on acute serofibrinous pericarditis secondary to acute pharyngitis, Proc. Staff Meet., Mayo Clin. 9: 637, 1934. Google Scholar16. PaulCastlemanWhite OBP: Chronic constricting pericarditis, Am. J. M. Sc. 216: 361, 1948. CrossrefMedlineGoogle Scholar17. RabinerSpecterRipsteinSchlecker SFLSCNAA: Chronic constricting pericarditis as sequel to acute benign pericarditis, New England J. Med. 251: 425, 1954. CrossrefMedlineGoogle Scholar18. ZivitzOshlag NJA: Eosinophilic pleural effusion and pericarditis with effusion in an allergic subject, J. Allergy 20: 136, 1949. CrossrefMedlineGoogle Scholar19. SoloffZatuchniJantonO'NeillGlover LAJOHTJRP: Reactivation of rheumatic fever following mitral commissurotomy, Circulation 8: 481, 1953. CrossrefMedlineGoogle Scholar20. Dressler W: Idiopathic recurrent pericarditis, Am. J. Med. 18: 591, 1955. CrossrefMedlineGoogle Scholar21. GittlerSchackVessel RJAH: The electrocardiogram one year after acute myocardial infarction, Am. Heart J. 51: 246, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication September 10, 1955.From the Department of Medicine, New York University, Post-Graduate Medical Center.Requests for reprints should be addressed to Maxwell L. Gelfand, M.D., 60 Gramercy Park, New York 10, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIdiopathic Pericarditis and PregnancyRelapsing Coxsackie Pericarditis Simulating Myocardial Infarction and Da Costa's SyndromeElectrocardiographic abnormalities in acute, convalescent, and recurrent stages of idiopathic pericarditisErkrankungen des PerikardStudies in pericarditisSHOCK AND ACUTE ABDOMINAL SYMPTOMS COMPLICATING ACUTE IDIOPATHIC PERICARDITIS*HAROLD R. WITHERBEE JR., M.D., MORTON LEE PEARCE, M.D. 1 September 1956Volume 45, Issue 3Page: 490-504KeywordsAnticoagulantsElectrocardiographyMyocardial infarctionUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 September 1956 PDF downloadLoading ...

Treatment of Acute Coronary Occlusion

The diagnosis of acute coronary occlusion has been facilitated and its treatment improved. At the onset of the attack the electrocardiogram may be normal or show only slight changes. The major therapeutic advances include oxygen administration, a low calorie diet, the judicious use of digitalis and quinidine, the avoidance of such drugs as Adrenalin and nitroglycerin, and the employment of anticoagulant and pressor drugs. Therapy must be individualized, particularly in reference to the time chair treatment is begun, the time of ambulation, and the time for returning to work. The majority of patients can be treated at home. The pain which ushers in the attack should be relieved immediately. For this purpose, morphine is most efficacious. Nitroglycerin is not effective, and may be dangerous. The patient's anxiety must be allayed; he should be reassured that he, like the vast majority of patients, will make a good recovery and resume a full, productive life. Indiscriminate prolonged bed-rest for all patients is inadvisable. The period of bed-rest is determined by the physical and psychic state of each patient. Some mild cases are permitted to be in a chair on the second or third day; others, after a week. Early chair treatment has definite advantages. In the average mild case, the patient begins to walk during the fourth week. The routine use of anticoagulants is unnecessary. They should be employed in patients with heart failure or shock, and in those who develop peripheral phlebitis, peripheral arterial embolism, or pulmonary embolism. When anticoagulants are administered, the patient should be under close supervision. We believe that anticoagulants, administered during the premonitory phase of coronary thrombosis, are inefficacious; they neither prevent nor hasten the progress of the thrombosis. Anticoagulants are contraindicated in patients with a history of bleeding tendency, ulcerative colitis, peptic ulcer, renal or hepatic disease, or a cerebrovascular accident. It is important to differentiate coronary occlusion from non-specific pericarditis, since anticoagulants appear to be harmful in this condition. The electrocardiogram should not be used as a criterion for determining the progress of the patient and the time when he may sit up, begin to walk, or return to work. Neither should undue reliance be placed upon the sedimentation rate as a guiding factor in treatment. The treatment of heart failure in coronary occlusion is the same as if coronary occlusion were not present, but special care is necessary to prevent digitalis intoxication. A low calorie diet is important, for it diminishes the work of the heart, prevents gastrocardiac reflexes, and reduces weight in the obese. Constipation and distention must be prevented. Cold milk and fruit juices should be avoided and laxatives used. Nausea and vomiting are benefited by the oral or intramuscular administration of anti-motion sickness drugs. Early treatment of shock is essential. The vasopressor drugs are helpful, if administered early. If congestive failure is a factor, strophanthin or digitalis should be given. Pulmonary edema requires immediate treatment with morphine. If necessary, aminophylline, strophanthin, mercurials, oxygen under pressure, and rotating tourniquets or phlebotomy are employed. The inhalation of alcohol vapor is occasionally efficacious. Arrhythmias occur frequently and often remit. The indications for the treatment of each type are discussed and the details outlined. Quinidine is not used routinely. Hiccough may be a serious problem. Reassurance of the patient is most important. Adequate sedation should be used. Numerous successful therapeutic measures are available. Cortisone and ACTH are not efficacious in coronary occlusion. Antibiotics are administered if pulmonary congestion or signs of congestive heart failure are present, or if the temperature is above 102° F. Whiskey should not be given in acute coronary occlusion, since it may increase the pulse rate. Smoking should be prohibited. The prognosis in coronary occlusion has greatly improved during the past 30 years. In private practice, the mortality rate during the first attack is now five per cent or less. Most patients can be rehabilitated within two or three months. The vast majority makes a fair or good recovery, more than half make an excellent functional recovery. Four out of five return to work.

Acute pericarditis.

Statistical studies of the frequency of the different etiologic types of acute pericarditis may be misleading because of an increasing recognition of nonspecific pericarditis. In our experience this form is the most common in private practice, while on the wards of a general hospital, tuberculous pericarditis is the most frequent variety. Despite improvements in diagnostic technics there still remains a significant number of patients with acute pericarditis, the etiology of which cannot be categorized accurately. This latter group will be narrowed only after further clinical description and laboratory study. The diagnosis of nonspecific pericarditis should be made carefully because of similarity of its onset to that of myocardial infarction and its benign course with tendency to relapse. Tuberculous pericarditis merits early recognition because of the improved prognosis following prompt treatment. Rheumatic pericarditis is often a problem in children and adolescents and indicates serious cardiac involvement; in adults the clinical course is generally more benign. Pericarditis occurring in uremia and myocardial infarction is usually an incidental finding in the course of a more important disease. Pyogenic pericarditis is now a rare occurrence except in certain infectious states. The treatment of acute pericarditis has been considerably improved by the introduction of the antibiotic drugs. The judicious use of pericardial paracentesis may be life-saving in certain instances or it may yield diagnostic information from which effective therapy can be instituted.

Recurrent tuberculous pericarditis.

Case Reports1 December 1952RECURRENT TUBERCULOUS PERICARDITISRAY C. JANOVSKY, M.D., JOHN F. BOETTNER, M.D., H. SCOTT VANORDSTRAND, M.D., F.A.C.P., DONALD B. EFFLER, M.D.RAY C. JANOVSKY, M.D.Search for more papers by this author, JOHN F. BOETTNER, M.D.Search for more papers by this author, H. SCOTT VANORDSTRAND, M.D., F.A.C.P.Search for more papers by this author, DONALD B. EFFLER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-6-1268 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptShock and pain are seldom considered to be prominent manifestations of tuberculous pericarditis. The onset of the disease is usually insidious, and pain, when present, has been most often reported as a dull ache, vaguely localized to the chest.1, 2, 3, 4, 5, 6, 7 In the case to be reported the patient was a robust, stoical individual who, many times, presented himself with the sole complaint of agonizing chest pain.CASE REPORTThe patient, a 45 year old telephone lineman, was first seen on December 29, 1945, because of an upper respiratory infection associated with ill-defined precordial pain. His...Bibliography1. BurchWinsor GET: Tuberculous pericarditis with effusion, Clinics 1: 166, 1942. Google Scholar2. Thompson WP: Primary tuberculosis of the pericardium, J. A. M. A. 100: 642, 1933. CrossrefGoogle Scholar3. FineKatz MJS: Clinically primary tuberculosis of the pericardium, Dis. of Chest 10: 60, 1944. CrossrefGoogle Scholar4. Clarke JA: Clinically primary tuberculous pericarditis, Am. J. M. Sc. 177: 115, 1929. CrossrefGoogle Scholar5. HeimannBinder HLS: Tuberculous pericarditis, Brit. Heart J. 2: 165, 1947. CrossrefGoogle Scholar6. HarveyWhitehill AMMR: Tuberculous pericarditis, Medicine 16: 45, 1937. CrossrefGoogle Scholar7. White PD: Chronic constrictive pericarditis, Circulation 4: 288, 1951. CrossrefMedlineGoogle Scholar8. Riesman D: Primary tuberculosis of the pericardium, Am. J. M. Sc. 122: 6, 1901. CrossrefGoogle Scholar9. StepmanOwyang TRE: Clinically primary tuberculous pericarditis, Ann. Int. Med. 27: 914, 1947. LinkGoogle Scholar10. Suzman S: Tuberculous pericardial effusion, Brit. Heart J. 5: 19, 1943. CrossrefMedlineGoogle Scholar11. BelletMcMillanGouley STMBA: Tuberculous pericarditis, a clinical and pathologic study based on a series of seventeen cases, M. Clin. North America 18: 201, 1934. Google Scholar12. BarrettCole AML: A case of tuberculous pericarditis, Brit. Heart J. 6: 185, 1944. CrossrefMedlineGoogle Scholar13. Giles WT: A case of tuberculous pericarditis with effusion treated by means of pneumopericardium, Am. Heart J. 7: 771, 1931-32. Google Scholar14. Brown M: Acute benign pericarditis, New England J. Med. 18: 666, 1951. CrossrefGoogle Scholar15. TalmageSuccasunna WGNJ: Acute benign pericarditis, a report of two cases in young adults, Am. Heart J. 29: 623, 1945. CrossrefGoogle Scholar16. LogueWendkos RBMH: Acute pericarditis of benign type, Am. Heart J. 36: 587, 1948. CrossrefMedlineGoogle Scholar17. Willius FA: Clinic on acute serofibrinous pericarditis secondary to acute pharyngitis, Proc. Staff Meet., Mayo Clin. 9: 637, 1934. Google Scholar18. NathanDathe DARA: Pericarditis with effusion following infections of the upper respiratory tract, Am. Heart J. 31: 115, 1946. CrossrefMedlineGoogle Scholar19. TaubenhausBrams MWA: Treatment of acute non-specific pericarditis with aureomycin, J. A. M. A. 142: 973, 1950. CrossrefGoogle Scholar20. Pohl AW: Acute pericarditis, a report of eight cases in which the etiology was "nonspecific" or cryptic, Ann. Int. Med. 32: 935, 1950. LinkGoogle Scholar21. Wolff L: Acute pericarditis simulating myocardial infarction, New England J. Med. 230: 422, 1944. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication March 22, 1952.From the Department of Medicine, St. Luke's Hospital, Cleveland, Ohio (Dr. Janovsky and Dr. Boettner), and from the Departments of Medicine (Dr. VanOrdstrand) and Surgery (Dr. Effler), Cleveland Clinic. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Historical PerspectiveTuberculous pericarditisOn pericardiocentesisTuberculous pericarditis∗Erkrankungen des PerikardPERICARDIAL BIOPSYPostviral myopericarditis associated with the influenza virusTuberculous pericarditis among veterans 1 December 1952Volume 37, Issue 6Page: 1268-1274KeywordsHospital medicineIschemiaPainShockSurgeryTuberculosisUpper respiratory tract infections Issue Published: 1 December 1952 PDF downloadLoading ...

Acute nonspecific pericarditis complicated by the development of a fibrous pericardium.

Case Reports1 August 1952ACUTE NONSPECIFIC PERICARDITIS COMPLICATED BY THE DEVELOPMENT OF A FIBROUS PERICARDIUMJOSEPH K. FREILICH, M.D.JOSEPH K. FREILICH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-37-2-388 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe clinical entity of acute nonspecific pericarditis has been clearly defined.1, 2, 3It is characterized by a history of an antecedent respiratory infection, followed after an interval of from several days to several weeks by the development of the signs and symptoms of pericarditis with effusion. These consist of paroxysmal substernal or precordial pains, usually severe, and usually aggravated by coughing, deep breathing or motion. In addition, one finds fever, leukocytosis, increased sedimentation rate and a pericardial friction rub. An associated pneumonitis or pleural effusion is not uncommon. There are characteristic electrocardiographic changes consisting of RS-T elevations and T...Bibliography1. BarnesBurchell ARHB: Acute pericarditis simulating acute coronary occlusion, Am. Heart J. 23: 247, 1942. CrossrefGoogle Scholar2. Burchell HB: Acute non-specific pericarditis, Modern Concepts of Cardiovascular Disease, 16: 3, 1947. Google Scholar3. LevyPatterson RLMC: Acute serofibrinous pericarditis of undetermined cause, Am. J. Med. 8: 34, 1950. CrossrefMedlineGoogle Scholar4. TaubenhausBrams MWA: Aureomycin in acute nonspecific pericarditis, J. A. M. A. 142: 973, 1950. CrossrefGoogle Scholar5. HarrisonWhite MBPD: Chronic constrictive pericarditis; a follow-up study of 37 cases, Ann. Int. Med. 17: 790, 1942. LinkGoogle Scholar6. Harrington SW: Chronic constrictive pericarditis. Partial pericardiectomy and epicardiolysis in twenty-four cases, Ann. Surg. 120: 468, 1944. CrossrefMedlineGoogle Scholar7. LuisadaFleischner AAFG: Studies of fluorocardiography: tracings of the left ventricle in myocardial infarction, Acta cardiol. 4: 308, 1948. Google Scholar8. GillickReynolds FGWF: Clinical application of electrokymography, California Med. 70: 1, 1949. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication March 30, 1951.From the Department of Medicine, The Chicago Medical School and the Mount Sinai Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byScalloping: Various signs in the chestRecurrent PericarditisRecurrent acute pericarditis: Follow-up study of 31 patientsConstrictive pericarditis following Coxsackie virus infectionAcute nonspecific pericarditis complicated by the development of constrictive pericarditisKlinik und Therapie des PanzerherzensElectrocardiographic abnormalities in acute, convalescent, and recurrent stages of idiopathic pericarditisErkrankungen des PerikardHerz- und Kreislaufstörungen bei InfektionskrankheitenHerz- und Kreislaufstörungen bei InfektionskrankheitenPERICARDIECTOMY FOR MASSIVE RECURRENT PERICARDIAL EFFUSION*†ROBERT JAY JAFFE, M.D., HAROLD KALLMAN, M.D.Newer laboratory aids in the differential diagnosis of acute pericarditisAcute Non-Specific Pericarditis. 1 August 1952Volume 37, Issue 2Page: 388-393KeywordsFeversGratitudeHospital medicineLeukocytosisPericardiumPleural effusionPneumonitisRadiologistsSigns and symptomsUpper respiratory tract infections ePublished: 1 December 2008 Issue Published: 1 August 1952 PDF downloadLoading ...

Myocardial involvement in acute nonspecific pericarditis: a report of three cases.

Article1 December 1951MYOCARDIAL INVOLVEMENT IN ACUTE NONSPECIFIC PERICARDITIS: A REPORT OF THREE CASESJOHN GODFREY, M.D.JOHN GODFREY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-6-1336 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor the past 10 years, increasing interest has been shown in acute pericarditis of obscure etiology, known commonly as acute nonspecific pericarditis or acute benign pericarditis. This syndrome is characterized by its onset with substernal or anterior thoracic pain, sometimes severe enough to require differentiation from myocardial infarction,1, 2and is associated with a pericardial friction rub, fever, leukocytosis and elevated sedimentation rate in the majority of instances. A pericardial effusion has appeared in approximately 20 per cent of these cases, and pleural effusion in about 25 per cent. Complete recovery in two to 12 weeks has been the rule,...Bibliography1. Wolff L: Acute pericarditis simulating myocardial infarction, New England J. Med. 230: 422, 1944. CrossrefGoogle Scholar2. BarnesBurchell ARHB: Acute pericarditis simulating coronary occlusion, Am. Heart J. 23: 247, 1942. CrossrefGoogle Scholar3. Burchell HB: Acute nonspecific pericarditis. Modern concepts of cardiovascular disease, Vol. 16, No. 3, 1947. Google Scholar4. Talmadge WG: Acute benign pericarditis, Am. Heart J. 29: 623, 1945. CrossrefGoogle Scholar5. UrschelBondySalley DLPKSM: Acute pericarditis, New England J. Med. 233: 399, 1945. CrossrefGoogle Scholar6. SmalleyRuddock REJC: Acute pericarditis: a study of 18 cases among service personnel, Ann. Int. Med. 25: 799, 1946. LinkGoogle Scholar7. NayBoyer RMNH: Acute pericarditis in young adults, Am. Heart J. 32: 222, 1946. CrossrefMedlineGoogle Scholar8. LogueWendkos RBMH: Acute pericarditis of benign type, Am. Heart J. 36: 587, 1948. CrossrefMedlineGoogle Scholar9. LevyPatterson RLM: Acute sero-fibrinous pericarditis of undetermined cause, Am. J. Med. 8: 34, 1950. CrossrefMedlineGoogle Scholar10. Pohl AW: Acute pericarditis: a report of eight cases in which the etiology was "nonspecific" or "cryptic," Ann. Int. Med. 32: 935, 1950. LinkGoogle Scholar11. NathanDathe DARA: Pericarditis with effusion following infections of upper respiratory system, Am. Heart J. 31: 115, 1946. CrossrefMedlineGoogle Scholar12. FinkelsteinKlainer DMJ: Pericarditis associated with atypical pneumonia, Am. Heart J. 28: 385, 1944. CrossrefGoogle Scholar13. Willius FA: Acute sero-fibrinous pericarditis secondary to acute pharyngitis, Proc. Staff Meet., Mayo Clin. 9: 637, 1934. Google Scholar14. Wolff L: Acute pericarditis with special reference to change in heart size, New England J. Med. 229: 423, 1943. CrossrefGoogle Scholar15. TabenhausBrams MWA: Treatment of acute nonspecific pericarditis with aureomycin, J. A. M. A. 142: 973, 1950. CrossrefGoogle Scholar16. SokolovLyon MTP: The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads, Am. Heart J. 37: 161, 1949. CrossrefMedlineGoogle Scholar17. BelletMcMillan STM: Electrocardiographic findings in acute pericarditis, Arch. Int. Med. 61: 381, 1938. CrossrefGoogle Scholar18. Vander VeerNorris JBRF: The electrocardiographic changes in acute pericarditis, Am. Heart J. 14: 31, 1937. CrossrefGoogle Scholar19. PortePardee DHE: The occurrence of the coronary T wave in rheumatic pericarditis, Am. Heart J. 4: 584, 1929. CrossrefGoogle Scholar20. HeinReavis GJC: Direct electrocardiograms from the human heart in situ, Circulation 1: 964, 1950. CrossrefGoogle Scholar21. KatzFeilScott LNHSRW: Experimental pericardial effusion, Am. Heart J. 5: 77, 1929. CrossrefGoogle Scholar22. BayGordonAdams EBWW: Electrocardiographic and blood pressure changes in experimental pericardial effusion and occlusion of the venae cavae, Am. Heart J. 8: 525, 1933. CrossrefGoogle Scholar23. HerrmannSchwab GE: Some experimental and clinical electrocardiographic observations on R-S-T and T changes in pericarditis, Tr. A. Am. Physicians 49: 229, 1934. Google Scholar24. Vaquez H: Quoted by Bellet, S., and McMillan, T. M.: Arch. Int. Med. 61: 381, 1938.17 CrossrefGoogle Scholar25. Covey GW: Fiedler's myocarditis, Am. J. Clin. Path. 12: 160, 1942. CrossrefGoogle Scholar26. Van Slyke DD: The effects of shock on the kidney, Ann. Int. Med. 28: 701, 1948. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Olean, New York*Received for publication September 27, 1950.From the Medical Service, Veterans Hospital, White River Junction, Vermont.Published with permission of the Chief Medical Director, Department of Medicine and Surgery, Veterans Administration, who assumes no responsibility for the opinions expressed or conclusions drawn by the author. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAdult heart disease due to the Coxsackie virus group B.Letter to the editorRelapsing Coxsackie Pericarditis Simulating Myocardial Infarction and Da Costa's SyndromeElectrocardiographic abnormalities in acute, convalescent, and recurrent stages of idiopathic pericarditisAdult Pericarditis and Myocarditis Due to Coxsackie Virus Group B, Type 5Acute idiopathic pericarditisPERICARDIECTOMY FOR MASSIVE RECURRENT PERICARDIAL EFFUSION*†ROBERT JAY JAFFE, M.D., HAROLD KALLMAN, M.D.Studies in pericarditisFatal case of acute idiopathic pericarditisIdiopathic recurrent pericarditisTHE SURGICAL TREATMENT OF CHRONIC PERICARDIAL EFFUSION AND CARDIAC TAMPONADEChronic Constrictive Pericarditis as a Sequel to Acute Benign PericarditisAcute Non-Specific Pericarditis. 1 December 1951Volume 35, Issue 6Page: 1336-1345KeywordsEtiologyFeversLeukocytosisMedical servicesMyocardial infarctionPleural effusionRiversSurgery ePublished: 1 December 2008 Issue Published: 1 December 1951 PDF downloadLoading ...

Non-specific pericarditis, early differentiation from acute myocardial infarction and danger of anti-coagulant therapy

Non-specific pericarditis, early differentiation from acute myocardial infarction and danger of anti-coagulant therapy

Acute nonspecific pericarditis; clinical, laboratory, and follow-up considerations.

Acute nonspecific pericarditis has been recognized with increasing frequency in recent years although there is reason to believe that it was considered distinct from rheumatic pericarditis almost 100 years ago. The authors have been able to secure follow-up information on 50 cases seen between 1930 and 1949. A few have shown persistent electrocardiographic changes, and calcification of the pericardium occurred in 1 case. In general the prognosis appears excellent and we have not observed constrictive pericarditis as a sequela.

Acute nonspecific benign pericarditis.

Although several small series of cases of acute non-specific pericarditis have been reported in recent years, there are several points of interest in this series of 11 cases seen in private practice in a subtropical climate. Eight were seen in one year. The disease doubtlessly occurs more frequently and is more widely spread than is generally suspected and in many instances is misdiagnosed as coronary occlusion. The differential diagnosis usually is not difficult if one keeps the possibility of acute pericarditis in mind. The importance of specific diagnosis is obvious, because immediate and ultimate prognosis as well as management in acute pericarditis is different from that in coronary occlusion. Barnes and Burchell1stated that acute benign nonsuppurative pericarditis is an important problem and that there must be instances in daily practice in which the lack of appreciation of distinctions results in pericarditis being mistaken for acute coronary occlusion. In

Acute pericarditis: a report of eight cases in which the etiology was "non-specific" or "cryptic".

Article1 May 1950ACUTE PERICARDITIS: A REPORT OF EIGHT CASES IN WHICH THE ETIOLOGY WAS "NON-SPECIFIC" OR "CRYPTIC"ARNOLD W. POHL, M.D., F.A.C.P.ARNOLD W. POHL, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-5-935 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAcute pericarditis usually occurs in the presence of more or less easily recognized infections elsewhere in the body, as with rheumatic fever, pneumococcic pneumonia, septicemia or tuberculosis, to mention the more common examples. That it may occur spontaneously and without the demonstration of any known infectious agent is not well known. Such cases have been called acute, non-specific pericarditis. The sudden onset and the severity of the chest pain may be such as to lead to the erroneous diagnosis of coronary thrombosis,1, 2, 3 or to pulmonary infarction.4The recognition of several cases of acute, primary or non-specific pericarditis in...Bibliography1. BarnesBurchell ARHB: Acute pericarditis simulating acute coronary occlusion, Am. Heart J. 23: 247, 1942. CrossrefGoogle Scholar2. Wolff L: Acute pericarditis simulating myocardial infarction, New England J. Med. 230: 422, 1944. CrossrefGoogle Scholar3. Burchell HB: Acute non-specific pericarditis, Modern Concepts of Cardiovascular Dis. 16: 1947, No. 3. Google Scholar4. Butsch WL: Acute pericarditis as a post-operative complication, Proc. Staff Meet., Mayo Clin. 12:737, 1937. Google Scholar5. Porter WB: Acute pericarditis, diagnosis and treatment of cardiovascular disease, 1945, F. A. Davis Co., Philadelphia. Google Scholar6. SmalleyRuddock REJC: Acute pericarditis: a study of eighteen cases among service personnel, Ann. Int. Med. 25: 799, 1946. LinkGoogle Scholar7. BurchWinsor GT: A primer of electrocardiography, 1946, Lea and Febiger, Philadelphia. Google Scholar8. NayBoyer RMNH: Acute pericarditis in young adults, Am. Heart J. 32: 222, 1946. CrossrefMedlineGoogle Scholar9. SmithWillius HLFA: Pericarditis. IV. Fibrinous pericarditis and soldier's patches, Arch. Int. Med. 50: 410, 1932. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Albany, New York*Received for publication October 9, 1948.From the Department of Medicine, Albany Medical College, Union University and Albany Hospital, Albany, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byElectrocardiographic abnormalities in acute, convalescent, and recurrent stages of idiopathic pericarditisHEMORRHAGIC PERICARDIAL FLUID IN ACUTE BENIGN NONSPECIFIC PERICARDITIS: REPORT OF A CASE AND REVIEW OF THE LITERATURE*CEILOUS L. WILLIAMS JR., M.D., JULIAN R. BECKWITH, M.D., F.A.C.P., J. EDWIN WOOD JR., M.D., F.A.C.P.Herz- und Kreislaufstörungen bei InfektionskrankheitenHerz- und Kreislaufstörungen bei InfektionskrankheitenStudies in pericarditisIdiopathic recurrent pericarditisAcute PericarditisAcute Non-Specific Pericarditis.RECURRENT TUBERCULOUS PERICARDITIS*RAY C. JANOVSKY, M.D., JOHN F. BOETTNER, M.D., H. SCOTT VANORDSTRAND, M.D., F.A.C.P., DONALD B. EFFLER, M.D.Fibrinous Pericarditis Secondary to Esophageal UlcerationMYOCARDIAL INVOLVEMENT IN ACUTE NONSPECIFIC PERICARDITIS: A REPORT OF THREE CASES*JOHN GODFREY, M.D.Nearly ten decades of interest in idiopathic pericarditisAcute Nonspecific Pericarditis 1 May 1950Volume 32, Issue 5Page: 935-948KeywordsEtiologyHospital medicineIschemiaMedical servicesPneumoniaRheumatic feverSepsisTuberculosis ePublished: 1 December 2008 Issue Published: 1 May 1950 PDF downloadLoading ...

TREATMENT OF ACUTE NONSPECIFIC PERICARDITIS WITH AUREOMYCIN

The clinical features of acute nonspecific pericarditis, an inflammatory condition of the pericardium, have been described by Burchell,1Logue and Wendkos,2Talmadge,3Wolff4and Barnes and Burchell.5Briefly, the condition is usually preceded by an upper respiratory infection or sore throat, but there are no evidences of active rheumatic infection in the joints or heart. Similarly, other causes for pericarditis, such as tuberculosis, myocardial infarction and uremia, are absent. The onset is generally abrupt with fever, malaise and substernal or precordial pain which is worse on deep breathing, movement of the trunk or swallowing. Partial relief of pain is attained by assumption of the sitting posture or by leaning forward. A pericardial friction rub is heard early, and the classic electrocardiographic patterns of acute diffuse pericarditis appear in most instances. Pericardial effusion may develop and may require paracentesis, but no permanent cardiac damage or harmful