Nonreciprocal effects in nanoelectronic devices offer unique possibilities for manipulating electron transport and engineering quantum electronic circuits for information processing purposes. However, a lack of rigorous theoretical tools is hindering this development. Here, we provide a general input-output description of nonreciprocal transport in solid-state quantum dot architectures, based on quantum optomechanical analogs. In particular, we break reciprocity between coherently-coupled quantum dots by dissipation-engineering in which these (so-called) primary dots are mutually coupled to auxiliary, damped quantum dots. We illustrate the general framework in two representative multiterminal noninteracting models, which can be used as building blocks for larger circuits. Importantly, the identified optimal conditions for nonreciprocal behavior hold even in the presence of additional dissipative effects that result from local electron-phonon couplings. Besides the analysis of the scattering matrix, we show that a nonreciprocal coupling induces unidirectional electron flow in the resonant transport regime. Altogether, our analysis provides the formalism and working principles towards the realization of nonreciprocal nanoelectronic devices.