The swirl flow minichannel heat sink has shown to be a promising alternative for thermal management of high heat flux applications, such as electronics and concentrated photovoltaics. Effective heat transfer enhancement strategies for this device are identified by studying the receptivity of temperature disturbances to a momentum forcing input. Steady state laminar flow is calculated numerically and experimental measurements are carried out to validate the results for subcritical Reynolds numbers. Using the framework of nonmodal stability theory, a harmonically driven linear perturbation problem is formulated, and the methodology to apply the local and parallel flow approximations based on order of magnitude arguments is detailed. The input-output response of temperature perturbations to forcing of the radial, azimuthal, and wall-normal momentum components is calculated for a range of wavenumbers, waveangles and temporal frequencies. The largest amplification is presented by streamwise vortices and streaks, followed by axisymmetric inward travelling waves, and then by streamwise propagating waves. Micromachining the channel walls with streamwise spiral grooves is proposed as a heat transfer enhancement technique. Excitation of streamwise independent structures in the wall-normal direction is expected, therefore maximum amplification should be obtained. Due to its simple implementation, we also propose using a pulsating flow rate as a heat transfer enhancement technique. Receptivity results for streamwise propagating waves of radial forcing show a response curve with moderate amplification for a wide range of actuation frequencies. Experimental work is conducted to measure the performance of the swirl flow channel heat sink using flow pulsations at the range of forcing frequencies suggested by the receptivity study. Compared to the unforced case, a lower wall temperature (up to 5°C cooler) was observed with pulsations, at the same imposed heat flux and flow rate. To get the same wall temperature as in the unforced case, a pumping power reduction of up to 26.6% was observed, and using the same pumping power resulted in up to a 10.3% Nusselt enhancement. Hydrodynamic receptivity was successfully used to identify effective heat transfer enhancement strategies, resulting in a significant performance improvement for the swirl flow channel heat sink. This physics based approach can be extended to other techniques, for instance, to select the wavelength of a wavy surface, the periodicity of surface roughness elements, or the frequency of acoustic vibrations.