Background and objectives. The consumption of new psychoactive substances (NPS), particularly among young people, remains a significant public health issue. The principal objective of this study was to identify the incidence and prevalence of NPS use among young people in Romania and the impact of the consumption on their mental health. Materials and methods. A cross-sectional study was conducted on a sample of 231 Romanian participants on March-April 2023. Data were collected through an online questionnaire and analyzed using GraphPad and Excel statistical software. Results. The prevalence of NPS use was 38.10% within the sample The analyzed data indicated an increased incidence of NPS use among male participants. Notably, most respondents who reported NPS use were students, accounting for 23.38% of users. Among the total of 88 NPS users, 22.68% consumed synthetic cannabinoids, 14.09% bath salts, and 13.75% used mephedrone. Less frequently consumed substances included synthetic opioids, methamphetamines, synthetic piperazines, Salvia divinorum, and MDPV. A significant proportion of users reported severe psychiatric symptoms including psychosis, depression and anxiety. Among non-users, awareness of the side effects of NPS influenced over half of them to avoid such substances. Conclusions. NPS use impacts predominantly young people. Organizing prevention and information campaigns about the implications of NPS use and its immediate harmful effects could help reduce its prevalence among young individuals.
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