Neuropsychological Diagnostics Research Articles

Age-related development trajectories of components of mental functions in children 4-17 years old

The present paper is dedicated to the problem of age-related changes in features of neuropsychological development. The sample consisted of 922 conditionally healthy subjects ranging from 4 to 17 years of age, comprising 603 boys and 319 girls. The study participants underwent neuropsychological diagnostics using the psychometric battery “Multifactorial Investigation of Neuropsychological Development” (MIND). The assessment was conducted in two psychological centres in Moscow, Russia. Trajectories of growth for 22 components of mental functions and the general level of development were obtained. This article examines the peculiarities of curve fitting using polynomials, Gompertz, Verhulst, and Schmalhausen-Brody functions. The study reveals that components of mental functions develop at different rates. Some of them complete their growth during the adolescence, while others continue to increase after the age of 18.

The Foundations and Practice of Neuropsychological Diagnostics in the Context of Forensic Psychiatric Examination

Background: cognitive impairments are comorbid for most mental disorders and can be important in assessing the ability of a subject to understand and control their actions in legally significant situations. The aim of review: аnalysis of neurobiological correlates and cognitive impairments in individuals suffering from mental disorders — organic personality disorder, schizophrenia, borderline personality disorder, in the context of forensic psychiatric examination. Material and methods: using keywords: “cognitive impairments in schizophrenia”, “cognitive impairments in organic personality disorders”, “cognitive impairments in personality disorders”, “MRI in schizophrenia”, “MRI in organic personality disorder”, “MRI in personality disorder”, “forensic neuropsychology”, “schizophrenia and criminal actions”, “organic personality disorders and criminal actions”, “personality disorders and criminal actions” the search and analysis of scientific publications was carried out in PubMed, Scopus, and RSCI databases over the past 5 years. Conclusion: schizophrenia shows deviations in the functioning of frontal and temporal lobes characterized by cognitive impairments: executive functions, attention, auditory-verbal memory, psychomotor slowness, inconsistent behavior, and deficits in volitional efforts. Borderline personality disorder is associated with reduced volume of the anterior cingulate gyrus, hippocampus, amygdala, and prefrontal cortex, dysfunctional interaction between limbic and prefrontal areas resulting in difficulties in emotion identification and impulsivity. Individuals with a history of traumatic brain injury (TBI) and secondary personality disorders exhibit diffuse gray matter damage affecting frontal, temporal, and parietal regions, emphasizing dysfunction of limbic-reticular complex structures with cognitive impairments including decreased thinking speed, attention stability, executive functions, auditory-verbal memory, visual-spatial memory, visual-motor coordination, and decreased impulse control. Individuals with mental disorders who commit criminal acts often exhibit deficiencies in frontal lobes and associated disturbances in executive components of mental activity, particularly cognitive flexibility and planning. Neuropsychological methods for studying cognitive functions can be used to obtain additional information in forensic psychiatric examinations.

Когнитивное и речевое развитие детей дошкольного возраста, зачатых путем вспомогательных репродуктивных технологий

<p style="text-align: justify;"><strong>Objectives. </strong>The mental health of children conceived using assisted reproductive technologies (ART) is a growing concern for parents and professionals. With a maximum compliance with the conditions for using reproductive technologies, the birth of a healthy child is expected. But some children conceived through artificial insemination have developmental problems, speech and/or cognitive problems. A pilot study was conducted on the cognitive and speech development of children from 3 to 8 years old with the aim of a comparative analysis of children from induced pregnancy with children conceived naturally, to determine the possible impact of ART methods on children's health.</p> <p style="text-align: justify;"><strong>Methods.</strong> The cognitive and speech functions of 115 children aged 3 to 8 years were studied: 54 children from induced pregnancy were included in the experimental groups (EG 1 and EG 2) and 61 children from natural conception were included in the control groups (CG 1 and CG 2). The method of neuropsychological diagnostics of children of L.S. Tsvetkova and methods of speech therapy examination (assessment of the state of facial and articulatory muscles, breathing, prosodic speech, general speech development) were used. The results were processed through the qualitative and quantitative assessment of the correspondence of the child’s cognitive and speech development to normative ontogenesis.</p> <p style="text-align: justify;"><strong>Results. </strong>It has been determined that children conceived through ART have a high percentage of perinatal risk: 35% of children (n=54) conceived through ART have: mental disorders (autism, intellectual disability) and various speech disorders in 77% of cases, — which has a negative impact on the development of cognitive activity. In children conceived naturally (n=61), the percentage of disorders was lower: in 47% of cases, cognitive disorders were noted, and in 60% of children, speech disorders of mild to moderate severity were identified.</p> <p style="text-align: justify;"><strong>Conclusions</strong>. The hypothesis about the possible influence of the fertilization methods used, the characteristics of the procedure, the health status of the parents before conception, the course of the mother’s pregnancy and other prenatal factors on the occurrence of developmental disorders in children conceived through ART is supported. An interdisciplinary approach to organizing research will allow a comprehensive study of the developmental features of children from induced pregnancy and the timely identification of possible dysontogenetic risk factors.</p>

The Significance of Chronic Fatigue in the Post-Covid Consultation and its Consequences for Outpatient Rehabilitation in the Context of Statutory Accident Insurance

The post-COVID consultation (PCC) is offered as part of a comprehensive range of treatment services provided by the statutory accident insurance for post-COVID patients to determine individual recommendations for further care. The aim of the study was to record the main symptoms and the associated restrictions on social and occupational participation in order to derive consequences for outpatient rehabilitation. In addition to a medical examination and a psychological consil, numerous assessments were carried out to evaluate the biopsychosocial state of health. 373 female (82.2%) and 81 male patients aged between 40 and 60 years from the professions of health and care services, education and pedagogy participated in the PCC since April 2021. Nearly all patients (98.2%) reported fatigue as a cardinal symptom of their post-COVID complaints, in combination with subjectively experienced limitations in brain functioning in over 73% of cases. The duration of the symptomatology persisted for an average of 14-15 months in both female and male insured persons. Thus, over 85% of the total sample can be classified as cases of chronic fatigue (Fatigue Scale). The severity of fatigue also proportionally affects quality of life (SF-36), feelings of anxiety and depression (HADS), psychological resilience (RS-13), and motor parameters such as maximum grip strength and endurance capacity. 54.3% of the patients also received a suspected mental diagnosis and 38.1% a recommendation for further neuropsychological diagnostics. For further treatment of the leading symptom of chronic fatigue, a multimodal and interdisciplinary outpatient rehabilitation is recommended, which should be oriented towards the treatment of the diagnosis of chronic fatigue syndrome (ME/CFS) and thus in particular towards a psychoeducational and rather than a curative therapeutic approach, and should consider aftercare strategies. Confirmed mental disorders and neuropsychological deficits are to be treated in addition.

Quantitative EEG Spectral and Connectivity Analysis for Cognitive Decline in Amnestic Mild Cognitive Impairment.

Mild cognitive impairment (MCI) is considered to be the borderline of cognitive changes associated with aging and very early dementia. Cognitive functions in MCI can improve, remain stable or progress to clinically probable AD. Quantitative electroencephalography (qEEG) can become a useful tool for using the analytical techniques to quantify EEG patterns indicating cognitive impairment. The aim of our study was to assess spectral and connectivity analysis of the EEG resting state activity in amnestic MCI (aMCI) patients in comparison with healthy control group (CogN). 30 aMCI patients and 23 CogN group, matched by age and education, underwent equal neuropsychological assessment and EEG recording, according to the same protocol. qEEG spectral analysis revealed decrease of global relative beta band power and increase of global relative theta and delta power in aMCI patients. Whereas, decreased coherence in centroparietal right area considered to be an early qEEG biomarker of functional disconnection of the brain network in aMCI patients. In conclusion, the demonstrated changes in qEEG, especially, the coherence patterns are specific biomarkers of cognitive impairment in aMCI. Therefore, qEEG measurements appears to be a useful tool that complements neuropsychological diagnostics, assessing the risk of progression and provides a basis for possible interventions designed to improve cognitive functions or even inhibit the progression of the disease.

Постковидный синдром: от биологии к нейропсихологии

Background. Postcovid syndrome or Long COVID is a new term introduced into medical practice by WHO after the COVID -19 pandemic. Long COVID affects patients who have recovered from COVID -19. Objectives. The purpose of this work is to understand cognitive deficits caused by COVID-19 from the point of view of neuropsychology and pathophysiology. Data Sources. Literature search was conducted in the following electronic databases: Pubmed, Google.scholar and Scopus databases. 63 articles were selected. Keywords for the literature review included “neuropsychiatry/neuropsychology”, “pathophysiology”, “COVID-19”, “SARS-CoV-2”. Methods. Review and analysis of COVID-19 studies in terms of its relation to the appearance of cognitive deficits in patients. Results. The SARS-CoV-2 virus enters the human body and affects the structures of the brain. Some of the symptoms such as fatigue, shortness of breath, problems with concentration and memory, loss or change of taste and smell, pain in muscles and joints as well as sleep disorders are preserved in post-COVID period and may be explained by the peculiarity of the virus interaction with central nervous system. Neuropsychological analysis of observed disorders based on the theory of three functional blocks of the brain by A. R. Luria helps to identify the affected zones of the functional systems of higher mental functions (HMF). Neuropsychological assessment makes it possible to plan rehabilitation programme or cognitive training, and help doctor in choosing an adequate drug therapy to compensate for cognitive impairment. Conclusions. SARS-CoV-2 causes damage to brain structures such as the brainstem, limbic system, prefrontal cortex and olfactory tract, which explains the observed symptoms. Neuropsychological diagnostics makes it possible to identify the impaired component of the HMF in patients with post-COVID syndrome, to plan an adequate rehabilitation programme, as well as to choose drug therapy.

Neuropsychological approach in assessing the voluntary attention of younger schoolchildren with different levels of success in learning

This article discusses the features of the neuropsychological approach aimed at overcoming retardations in mental development, preventing and solving emerging difficulties in teaching children of primary school age and involving the construction of psychological and diagnostic work with a child, taking into account his individual typological neuropsychological characteristics: the state of higher mental functions, highlighting strengths and weaknesses, components of the development of higher mental functions. The article contains data on the features of the state of voluntary attention in younger students with different success in educational activities, provides information on the forms of attention, and describes the external manifestations of impaired voluntary attention. The article contains a description of a study conducted among second grade students aimed at assessing such properties of attention as work efficiency, degree of development and mental stability using the “Schulte Table” technique. A detailed comparative analysis of the characteristics of voluntary attention in 81 schoolchildren of 170 a general education school with different success in learning activities is described: successful in learning, with partial and complex learning difficulties. Significant differences were revealed in children of primary school age, depending on the success of education. The importance of timely neuropsychological diagnostics of second graders which helps to identify the neuropsychological causes of partial and complex learning difficulties of children, and also allows to outline ways of corrective and developmental assistance to younger students in order to optimize the state of HMF (higher mental functions) and accordingly, to overcome the educational problems of children of primary school age is actualized.

Features of Neuropsychological Support of Patients with Impaired Consciousness at the Early Stage of Rehabilitation: a Narrative Review

INTRODUCTION. In the neuropsychological support of patients with impaired consciousness at an early stage of rehabilitation, methodological and practical problems arise related to the choice and procedure for using methods of neuropsychological diagnostics and neuropsychological rehabilitation. To develop methods of working with such patients, it is necessary to address the concepts of the structure of consciousness and the content of consciousness.
 RESULTS. The article presents a review of the literature devoted to the problem of the work of a neuropsychologist with patients with impaired consciousness. In the reviewed literature, attention is drawn to the insufficient development of the neuropsychological content of the concept of “consciousness”; methodological and procedural limitations that arise when a neuropsychologist works with patients with disorders of consciousness of varying degrees of severity; the possibilities of conducting and limiting psychostimulotherapy and sensory stimulation in domestic and foreign approaches are discussed.
 CONCLUSION. The analysis of publications on the topic of accompanying patients with impaired consciousness reflects the presence of a number of unresolved issues. At the present stage of development of neuropsychological work with patients with impaired consciousness, there is no single approved and detailed protocol regulating the conduct of neuropsychological diagnostics and neurorehabilitation with them. The problem is at the stage of solution and requires further research.

Cognitive effects after ECT: how to treat them?

AbstractHow far have we progressed in the field of treating cognitive side effects? Six months after the last ECT treatment, about 15% of patients still have such symptoms, limiting daily life. So far, studies in the field of cognitive training for ECT-related cognitive side effects show few positive effects. Nevertheless, these patients seem to help well. Because they have no structural damage to their brain, training with long-term effectiveness may be available for them. Amsterdam University Medical Centers started the CONNECT clinic (Cognitive and Neuropsychological Aftercare ECT) in early 2022 for diagnosis and treatment of patients with long-term cognitive complaints (longer than six months) that hamper their daily functioning. After the intake and neuropsychological diagnostics, treatment starts if there is an indication. Patients are then offered ’cognitive strategy training’ in an individual course. Developed in the field of neuropsychological rehabilitation, these help to get a grip on cognitive complaints by improving memory or executive functioning with learning strategies. Our initial experiences with patients show that patients master these strategies very well and quickly. We present a pilot project from the Amsterdam UMC where an individualized treatment-programme for long-term cognitive complaints after ECT is being implemented and evaluated.Disclosure of InterestNone Declared

Cognitive Behavioral Psychotherapy after COVID-19: Opportunities and Prospects

This article reviews domestic and foreign studies on cognitive behavioral therapy techniques in treating cognitive disorders in former COVID-19 patients. Coronavirus-induced cognitive disorders include damage to the nervous system as a result of respiratory distress syndrome, cytokine storm, cerebral vascular thrombosis, direct exposure to SARS-Cov2, and inadequate immune response. Concomitant mental illnesses include autistic disorders, dementia, cognitive decline, eating disorders, suicidal behavior, anxiety, depression, post-traumatic stress, insomnia, etc. Diagnostic methods usually take into account a complex violation of mental activities, e.g., short memory span, attention deficiency, slow thinking, and various affective disorders. As a result, diagnostic methods can be divided into several areas: neuropsychological diagnostics of cognitive functions (MMSE, MOCA, FAB), identification of inadequate attitudes and behavior (WCQ, SPB, DAS), identification of violations of daily activity (The Barthel Scale), identification of psychological and psychiatric issues (Hospital Anxiety and Depression Scale, State-Trait Anxiety Inventory, Hamilton Rating Scale for Depression). Psychological care for former COVID-19 patients relies on some basic principles. Cognitive behavioral psychotherapy techniques aim at correcting cognitive distortions, teaching relaxation and self-regulation, improving problem-solving skills, and restoring cognitive functions.

Automated Computerized Neuropsychological Diagnostics in Multiple Sclerosis

Abstract: Cognitive deficits are common in multiple sclerosis (MS), necessitating diagnosis and constant monitoring. However, frequent neuropsychological assessments are costly and not always feasible. A computerized assessment of basic cognitive functions could contribute to better patient care in this regard. The primary cognitive inventory of the Memory and Attention Test (MAT-COBI) constitutes such a tool. In this feasibility study, we tested N = 44 patients with MS with a standardized neuropsychological assessment consisting of established screening procedures (Brief International Cognitive Assessment in MS [BICAMS] and Brief Repeatable Battery [BRB] and three subtests of the Test Battery of Attentional Performance (TAP). The results of these procedures were considered a gold standard for assessing which patients were cognitively impaired or cognitively unaffected. We also administered the MAT-COBI and compared the results to the gold standard. While the results of an exploratory correlation analysis pointed toward the interpretation that the the MAT-COBI adequately operationalized the basic cognitive domains of attention, memory, and executive, sensitivity was insufficient (32.3 %), while specificity reached 92.3 %. A closer look at the single cognitive domains showed marginal differences across domains (sensitivity ranged from 0–24 %, specificity: 89.5 %-100 %). Based on these results, the MAT-COBI does not appear to be a suitable tool for differentiating between cognitively preserved and cognitively impaired patients with MS. We discuss possible explanations and implications for automated cognitive diagnostics.

Regression-Based Normative Data for the Montreal Cognitive Assessment (MoCA) and Its Memory Index Score (MoCA-MIS) for Individuals Aged 18-91.

(1) Background: There is a need for a brief assessment of cognitive function, both in patient care and scientific research, for which the Montreal Cognitive Assessment (MoCA) is a psychometrically reliable and valid tool. However, fine-grained normative data allowing for adjustment for age, education, and/or sex are lacking, especially for its Memory Index Score (MIS). (2) Methods: A total of 820 healthy individuals aged 18–91 (366 men) completed the Dutch MoCA (version 7.1), of whom 182 also completed the cued recall and recognition memory subtests enabling calculation of the MIS. Regression-based normative data were computed for the MoCA Total Score and MIS, following the data-handling procedure of the Advanced Neuropsychological Diagnostics Infrastructure (ANDI). (3) Results: Age, education level, and sex were significant predictors of the MoCA Total Score (Conditional R2 = 0.4, Marginal R2 = 0.12, restricted maximum likelihood (REML) criterion at convergence: 3470.1) and MIS (Marginal R2 = 0.14, REML criterion at convergence: 682.8). Percentile distributions are presented that allow for age, education and sex adjustment for the MoCA Total Score and the MIS. (4) Conclusions: We present normative data covering the full adult life span that can be used for the screening for overall cognitive deficits and memory impairment, not only in older people with or people at risk of neurodegenerative disease, but also in younger individuals with acquired brain injury, neurological disease, or non-neurological medical conditions.

Comprehensive assessment of the speech development of children conceived by IVF

Introduction. The high frequency of the use of assisted reproductive technologies and the inconsistency of information about the parameters of the cognitive development of IVF children determined the formulation of the research problem.The purpose of the work is to assess the originality of the speech development of children and adolescents conceived using the IVF procedure. The age of the children at the time of the survey was from 5 to 15 years.Methods and materials. A sample of 51 children (29 boys), mean age (7.9±2.8) years, 14 children had psychiatric diagnoses (ASD, mental retardation, etc.). Research methods: speech therapy assessment of speech development, neuropsychological diagnostics according to L.S. Tsvetkova, WICS, descriptive statistics, correlation analysis.Results. 41% of children had mild variants of speech development delay under 3 years old, 59 % of children had normal speech development. With age, the frequency of detected deviations in speech development decreases, so that in older age group (from 11 to 15 years old), 85 % have normotypical development of speech. Correlation analysis showed the originality of the correlations of the parameters of speech development, neuropsychological assessment, and scores on Wechsler subtests.Conclusions. An unambiguous conclusion about the violation of speech development in children conceived by IVF cannot be drawn, however, in the presence of mental pathology and taking into account the age of the mother and the number of ART procedures, attention should be paid to the provision of speech therapy and neuropsychological correction from an early age.

Evolution of Neuropsychological Deficits in First-Ever Isolated Ischemic Thalamic Stroke and Their Association With Stroke Topography: A Case-Control Study.

Background:The thalamus plays an essential role in cognition. Cognitive deficits have to date mostly been studied retrospectively in chronic thalamic stroke in small cohorts. Studies prospectively evaluating the evolution of cognitive deficits and their association with thalamic stroke topography are lacking. This knowledge is relevant for targeted patient diagnostics and rehabilitation.Methods:Thirty-seven patients (57.5±17.5 [mean±SD] years, 57% men) with first-ever acute isolated ischemic stroke covering the anterior (n=5), paramedian (n=12), or inferolateral (n=20) thalamus and 37 in-patient controls without stroke with similar vascular risk factors matched for age and sex were prospectively studied. Cognition was evaluated using predefined tests at 1, 6, 12, and 24 months. Voxel-based lesion-symptom mapping was used to determine associations between neuropsychological deficits and stroke topography.Results:Patients with anterior thalamic stroke revealed severe deficits in verbal memory (median T score [Q1–Q3]: 39.1 [36.1–44.1]), language (31.8 [31.0–43.8]), and executive functions (43.8 [35.5–48.1]) at 1 month compared with controls (verbal memory: 48.5 [43.6–61.0], language: 55.7 [42.3–61.1], executive functions: 51.3 [50.1–56.8]). Patients with paramedian thalamic stroke showed moderate language (44.7 [42.8–55.9]) and executive (49.5 [44.3–55.1]) deficits and no verbal memory deficits (48.1 [42.5–54.7]) at 1 month compared with controls (59.0 [47.0–64.5]; 59.6 [51.1–61.3]; 52.5 [44.2–55.3]). The language and executive deficits in paramedian thalamic stroke patients almost completely recovered during follow-up. Intriguingly, significant deficits in verbal memory (44.7 [41.5–51.9]), language (47.5 [41.8–54.1]), and executive functions (48.2 [46.2–59.7]) were found in inferolateral thalamic stroke patients at 1 month compared with controls (50.5 [46.7–59.9]; 57.0 [51.2–62.9]; 57.4 [51.2–60.7]). Language, but not executive deficits persisted during follow-up. Voxel-based lesion-symptom mapping revealed an association of verbal memory deficits with anterior thalamus lesions and an association of non-verbal memory, language, and executive deficits with lesions at the anterior/paramedian/inferolateral border.Conclusions:All 3 stroke topographies exhibited significant deficits in diverse cognitive domains, which recovered to a different degree depending on the stroke localization. Our study emphasizes the need for comprehensive neuropsychological diagnostics to secure adequate patient rehabilitation.

Cognitive Screening by the Doctor - What makes sense?

For initial cognitive diagnostics in the practice, various screening tools in the form of short paper-pencil-tests are available. Such initial screenings take between 5 and 15 minutes, but do not replace detailed neuropsychological diagnostics. Of the screening-tools reviewed, DemTect is suitable for suspected early onset dementia, while MMSE and MoCA cover other cognitive domains in greater detail. BrainCheck provides clear conclusion results and is recommended for practice. A more comprehensive diagnosis of dementia is not possible with the screening tools reviewed. However, they can help to decide whether a detailed dementia analysis is necessary or whether one can wait with it. The screening methods reviewed are freely available on the internet.

Особенности когнитивной и эмоциональной сфер подростка с патологией эпифиза и сопутствующим нарушением речи: анализ единичного случая

<p style="text-align: justify;">The study of the features of cognitive impairments in various cerebral organic pathologies allows us to understand the role of individual structures of the brain in the implementation of mental activity and determine the appropriate ways of providing psychological assistance to patients. In a situation of rare pathology, the analysis of individual clinical cases is useful. The aim of this research was to study the state of cognitive functions in a 13-year-old male teenager with a cystic restructuring of the pineal gland and concomitant undifferentiated impairment of expressive speech. Changes in the epiphysis were detected in the patient in less than a month before this psychological study. During the examination, methods of pathopsychological and neuropsychological diagnostics, and projective graphic tests were used. In the course of neuropsychological research on a teenager, a violation of the ability to compose a syllabic kinetic scheme of utterance and, in general, a lack of dynamic and kinesthetic praxis, as well as interhemispheric interaction and auditory-speech memory were revealed. The main ways of providing psychological assistance to the patient were identified: neuropsychological correction aimed at restoring impaired speech function based on preserved higher mental functions, and restoration of the communicative function of speech. The obtained results of psychological research require further understanding and verification, primarily in order to understand the pathogenesis of cognitive disorders in the situation of cystic pineal gland rearrangement.</p>

ОЦЕНКА УПРАВЛЯЮЩИХ ФУНКЦИЙ И ФУНКЦИЙ РЕГУЛЯЦИИ АКТИВНОСТИ У ДЕТЕЙ 6–9 ЛЕТ: КОНФИРМАТОРНЫЙ ФАКТОРНЫЙ АНАЛИЗ ДАННЫХ НЕЙРОПСИХОЛОГИЧЕСКОГО ОБСЛЕДОВАНИЯ

Relevance. In the study, we discuss the neuropsychological measures and relationship of two important groups of cognitive functions, namely, executive functions and functions of activation regulation. Th e study of the structure of these functions and the possibility of assessing their state in children of preschool and primary school age by methods of neuropsychological diagnostics and computerized testing are important from two points of view. First, it is an important issue in neuropsychological practice. Second, it is one of the ways to better understand cognitive development at this age. Objectives. Development and estimation of factor models that establish the relationship between the results of neuropsychological diagnostics of various groups of cognitive functions associated with executive functions and regulation of activation. Methods.434 children from 6 to 9 years old (from senior preschoolers to third graders) participated in the study. All children underwent neuropsychological examination adapted for children of 6–9 years, and they also performed tests from a computerized neuropsychological examination battery for children of 6–9 years. Th e results were used to conduct a confi rmatory factor analysis. Results and conclusions. We proposed models that include three factors. Th e fi rst factor corresponds to executive functions and two others relate to the regulation of activation. According to our model, the functions of activation can be divided into two factors: a factor of hyperactivity/impulsivity and a factor of fatigue/sluggishness. Model fi t indices showed good agreement with empirical data. Th e combined use of indicators of both traditional and computer neuropsychological examination makes the estimations of the model better. Th us, in the study we revealed parameters of the performance on the neuropsychological tests that can be used as indicators of the state of executive functions and functions of activation regulation. Th e weakness in one of the components of activity regulation can lead to specifi c patterns of behavior which are manifested in the neuropsychological examination. A more serious and extensive defi cit of one of the functions can lead to the appearance either of attention defi cit hyperactivity disorder or of sluggish cognitive tempo.

Neuropsychological Support for Teaching Young School-Age Children Annotation

The article is devoted to the problems of neuropsychological support of the educational process in elementary school, prevention possible disorders of primary school children’s mental processes and neuropsychological correction of difficulties in their learning. The neuropsychological causes of school failure are generalized (summarized). The methods of correctional and developmental education of elementary school children with specific neuropsychological features are analyzed. Neuropsychological factors of educational failure, particulary left-handed children and psychophysiological principles of special children’s psychological and pedagogical support in an inclusive environment are described. Organizational-didactic, diagnostic and correctional conditions of individual neuropsychological support of elementary school education are analyzed. A correctional and developmental program for neuropsychological diagnostics and correction of young schoolchildren’s educational failure is developed. The neuropsychological approach to the psychological and pedagogical supervision of first-grade pupils, taking into account their learning success, the level of communicative skills development and cognitive mental processes are come near.

Dynamics of Neuropsychological Symptoms during the Training of Executive Functions in Neurological Patients

Executive function disorder rehabilitation in neurological patients is associated with many difficulties. We investigated the effectiveness of group training, proposed by B. Wilson et al., which has the model of frontal lobes functioning by D. T. Stuss as the theoretical background. The study participants were 16 patients with executive function disorder caused by TBI, strokes, and infections. The training was shortened from 9 weeks to 3 and adopted to the conditions of the rehabilitation centre where the study was held. The evaluation of training effectiveness was carried out by the methods of neuropsychological diagnostics proposed by A. R. Luria as well as standardized quantitative tests (CWIT test, Raven test, FAB) and questionnaires (EBIQ) aimed at assessing the state of executive functions and general well-being. In result positive trends, but not reaching the level of significance, were revealed in the performance of all evaluating methods, with the exception of “arithmetic problems” and “inhibitory control” as part of the FAB test. Statistically significant result was obtained concerning such tests as “counting”, “analysis of story pictures”, and index of total uncorrected errors in the CWIT test. Thus, the results of eventual assessment showed positive dynamic of executive functions state.

Psychometrics and diagnostics of Italian cognitive screening tests: a systematic review.

Cognitive screening tests (CSTs) are crucial to neuropsychological diagnostics, and thus need to be featured by robust psychometric and diagnostic properties. However, CSTs happen not to meet desirable statistical standards, negatively affecting their level of recommendations and applicability. This study aimed at (a) providing an up-to-date compendium of available CSTs in Italy, (b) report their psychometric and diagnostic properties, and (c) address related limitations. This review was implemented by consulting Preferred Reporting Items for Systematic Reviews and Meta-Analyses and pre-registered on the International Prospective Register of Systematic Reviews. Standardization and usability studies focusing on norms, validity, reliability, or sensitivity/specificity (and derived metrics) in adults were considered for eligibility. Quality assessment was performed by means of an ad hoc checklist collecting information on sampling, psychometrics/diagnostics, norming, and feasibility. Sixty studies were included out of an initial N = 683. Identified CSTs (N = 40) were classified into general, domain-, and disease-specific (N = 17, 7, and 16, respectively), the latter being less statistically robust than remaining categories. Validity and reliability evidence was provided for 29 and 26 CSTs, respectively, sensitivity/specificity for 20 and norms for 33. Prevalence- and post-test-based diagnostic metrics were seldomly represented; factorial structures, ceiling/floor effects, and acceptability rarely investigated; content, face, and ecological validity never assessed. Although available Italian CSTs overall met basic psychometric/diagnostic requirements, their statistical profile often proved to be poor on several properties that are desirable for clinical applications, with a few exceptions among general and domain-specific ones.