From the current general situation of big data in medical systems, most of the medical system architectures of comprehensive related literature are based on cloud computing. With the deepening of big data application in the medical system, the drawbacks of medical network systems are apparent, for example, long network time delay, cloud computing overload, information leakage. A new intelligent medical system based on fog computing and IoT technology is proposed to effectively solve the problem of big data application through the comprehensive analysis of many works of literature. Compared with the traditional cloud computing model, the system which adopts a distributed fog computing model based on edge computing has the advantages of reducing network delay and plays its benefits of distributed, edge and decentralization. That the system takes advantage of IoT’s features of multi-node, low-energy consumption and big data technology is a new type of medical system that integrates intelligence and big data application. The system is effective through the application and practice of many medical institutions. In short, this system has several characteristics. For example, it can effectively improve medical intelligence and big data processing ability, significantly reduce network delay, effectively improve data security and effectiveness, largely improve the management level and service quality of medical institutions, play the important role of artificial intelligence and big data in the medical field, and greatly improve disease screening rate and reduce misdiagnosis rate. Ultimately it leads to reducing the contradiction between doctors and patients, providing patients with more convenience, faster and more efficient service quality, and alleviating the current situation of difficult and time-consuming medical treatment.