A network of monazite-rich, coarse-grained veins and fine-grained veins permeating the mid-Proterozoic Concordia Granite in the Kliphoog area near Springbok, Namaqualand, North Cape Province, South Africa, are described with respect to their whole-rock chemistry, petrography, mineralogy, and mineral chemistry along with zircon and monazite geochronology. Chondrite-normalized trace element data indicate that the coarse-grained veins are enriched in LREE relative to the Concordia Granite with HREE enrichment being somewhat variable. HREE in altered Concordia Granite, at the contact with the coarse-grained vein, are heavily depleted compared to unaltered Concordia Granite while the LREE show the same approximate abundances. Chloritization is common in the coarse-grained veins along mineral grain boundaries with chlorite replacing most of the orthopyroxene megacrysts, though occasional remnants of orthopyroxene remain in the core. A traverse across one of the coarse-grained veins showed no obvious mineral chemical trends between the vein and surrounding granite. Relic Fe-rich megacryst orthopyroxene has an Al2O3 content of around 2.0 wt% suggesting formation at around 700 °C. The Fe-rich biotite has mean Ti values ranging from TiO2 = 4.1 to 1.2 wt% indicating formation at 700–800 °C. The coarse-grained veins and fine-grained veins are characterized by abundant accessory Th-rich monazite, heterogeneously distributed in the veins. Lesser amounts of monazite are found in the granite. Other accessory minerals in the veins and granite include zircon and rare fluorapatite. Back-scattered electron imaging shows that the anhedral to euhedral monazite grains (up to more than 1500 μm in size) tend to be complexly zoned with light and dark areas. Lighter areas are more enriched in Th and/or Ce than darker areas. This complex zoning can occur as magmatic/sector zoning and more commonly as a complex series of metasomatic alteration events. Metasomatic textures, which are due to variable fluid-induced mobility of Th, U, and REE, are the result of a coupled dissolution-reprecipitation process and have been reproduced experimentally using high pH alkali-bearing fluids. The analysis of seven zircon cores from the Concordia Granite yields a concordia age of 1173 ± 15 Ma suggesting that an age of ca. 1170 Ma most likely represents the true emplacement age of the Concordia Granite. The mean 207Pb/206Pb age of 1042 ± 9 Ma obtained on zircon from the main coarse-grained vein is interpreted as the crystallization age of the vein. 207Pb/235U monazite ages are highly variable in the veins and Concordia Granite host, ranging from ca. 1050 to 1000 Ma. This supports the petrographic and mineral chemistry evidence that the monazite U--Pb system was variably affected by a continuous or multi-pulse metasomatic/metamorphic event(s) occurring between 1050 and 1000 Ma. U--Pb analyses of deformed monazite crystals from a radioactive sinistral shear zone of the Kliphoog area yield a mean 207Pb/235U age of ca. 1006 ± 9 Ma, indicating that the late circulation of Th-LREE-rich fluids synchronous with strike-slip deformation occurred at ca. 1000 Ma. On a regional scale, the intrusion of the Kliphoog coarse-grained vein is contemporaneous with granulite-facies metamorphism as well as the A-type granitoid magmatism of the Spektakel Suite, mafic magmatism of the Koperberg Suite, and emplacement of the monazite vein-type deposit at Steenkampskraal. Therefore, a genetic relationship between the formation of monazite-rich Kliphoog veins and these metamorphic, magmatic, and metallogenic events is proposed.