Researchers in India have designed a physiologically controlled ankle prosthesis that is capable of mimicking the natural movements and flexibility of a human foot. To find out more about this promising device we spoke to Oishee Mazumder and her colleagues at Indian Institute of Engineering Science and Technology to find out more. The important considerations to take into account when designing ankle-foot prostheses are low cost, inclusion of a power saving mode and ensuring the foot is mechanically resilient in power-off mode. Commercially available ankle foot prostheses are completely passive, and consequently, their mechanical properties remain fixed with walking speed and terrain. However, human ankle stiffness actually varies within each gait cycle (stride) and also with walking speed, which must be taken into account in prosthetic design. Below-knee amputees who use passive ankle foot prostheses also exhibit non-symmetric gait patterns and high metabolic ambulatory rates. The primary challenges in this field are associated with size, weight, controlling parameters, sensor fusion, realisation in embedded platform and the final cost of the product. Our group aims to make user friendly prototypes with physiological control by using multimodal sensory input signals. Limitations of current prosthetic technology includes: inability to provide net power at the joints (passive prostheses), high cost and the absence of feedback systems. Also, loss of net power generation at the lower limb impairs the ability of the prosthetics to biomechanically restore normal locomotive functions during many locomotive activities, such as walking, running and jumping. The elevated metabolic demand and slower preferred speeds of transtibial amputees are likely to be the cause of conventional passive prosthetics being unable to produce power at the ankle. In our published Letter we report the design and development of a wearable, low-cost, low-power prosthetic active ankle foot. The foot is controlled by myoelectric, inertial and pressure sensors that are actuated by custom designed servo motors, thus ensuring natural ankle spring-like behaviour is created. Our reported system is adaptable to variation of cadence and different terrain. Most modern ankle-foot prostheses employ a single spring in their design, such as a carbon fibre leaf spring. The gait of an amputee who uses these passive compliant prostheses mimics the unaffected ankle during normal walking, but deviates from normal as walking speed increases. Common ankle design is mostly related with DC motor and proper spring actions. In the present development, spring stiffness is adjusted to control the motor action in each gait phase. Our design is a cost-effective solution for transtibial amputees, which will help them regain their lost mobility in a relatively small time span. The design concept that we have followed can also be utilised in gait analysis, orthotic design in spinal cord injury (lower body exoskeleton) and in rehabilitation devices. As an extension of the concept of myoelectric controlled active ankle foot prosthesis, we have already started on the development of a lower limb active exoskeleton and its control strategy for regenerating and enhancing mobility. Immediately, the device can be improved in several ways, such as by the introduction of a low-weight, high-strength carbon nanotube-based fibre structure, long-life packing sensors and the incorporation of compact light-weight actuators. In the long run, the knowledge that we have developed will be used to design lower body exoskeleton devices with intelligent ankle feet. Prosthetic ankle prototype with custom designed servo motor to enable amputees to have physiological control of the artificial limb. Labelled design of the fabricated ankle foot prosthetic prototype. The device is currently under clinical testing with testing already carried out on three subjects under the supervision of a qualified prosthesist. The remaining challenges that we have yet to address are the need to reduce the limbs, weight, incorporate an efficient actuator and improve the battery power. A completely new prototype is under development, which will take care of the described deficiencies of the existing system. Amputation in general often leads to loss of work and mental disturbance. Every amputee needs training and counselling to be habituated and comfortable with the prosthetic device. This requires frequent follow up in rehabilitation centres. In many cases, such extensive follow-ups are not possible and desired results are not achieved. To address this we would like to develop an electromyogram (EMG) based rehabilitation, which will serve dual-purpose of regenerating and strengthening EMG signals and provide interactive training for prosthetic use.