Introduction. The objective thickness measurement of retinal nerve fiber layer (RNFL) is now possible with scanning laser polarimetry (GDx VCC). The TSNIT (temporal-superior-nasal-inferior-temporal) parameters are: TSNIT Average, Superior Average, Inferior Average, TSNIT Standard Deviation, Inter-eye-Symmetry and nerve fiber indicator (NFI). TSNIT Standard Deviation captures the modulation (peak to trough difference) of the double-hump pattern. A normal eye will have high modulation in the double-hump RNFL pattern, while a glaucoma eye will typically have low modulation in the double-hump pattern. As a result, high modulation will have a high TSNIT Standard Deviation value while low modulation will have low TSNIT Standard Deviation value. Objective. Our research aim was to evaluate and to compare the TSNIT Average and TSNIT Standard Deviation in glaucomatous patients with myopiс refraction and patients with myopia. Materials and methods. We examined two matched patient groups: basic - myopic patients with open-angle glaucoma 79 subjects (112 eyes) and control group 21 patients with myopia (39 eyes). All patients underwent imaging with the scanning laser polarimeter with variable corneal compensation GDx VCC. GDx parameters were TSNIT Average and TSNIT Standard Deviation. The Kruskal-Wallis test, the Mann-Whitney U-test and Spearman's rank correlation coefficient was applies for comparing groups and assessing the correlation. P values of P 0,05). The study demonstrated also a significant negative correlation of myopia grade and TSNIT Standard Deviation (rs = -0,3; P = 0,002) and a significant inverse correlation between the open-angle glaucoma stage and TSNIT Standard Deviation (rs = - 0,3; P = 0,03).