Negative Health Effects Research Articles

Assessment of metals and anions in tap, river, wastewater, and sludge: comparison of hotplate- and microwave-assisted digestion

In this study, the analysis of metals in tap, river, wastewater, and sludge samples was conducted using ICP−OES after hotplate- or microwave-assisted digestion. Both digestion methods produced a good degree of accuracy, indicating their suitability for the analysis of the studied metals in water samples. From method development studies, 100 mL of HNO3 was found to be the optimum sample volume and acid type for digestion. The average concentrations obtained ranged from 4.9–410.8 µg/L, 5.9–465.0 µg/L, 3.6–425.4 µg/L, 16.1–647 µg/L and 9.7–784 µg/L in tap water, river, influent, effluent, and sludge samples, respectively. All metals were below their maximum permissible limits, with the exception of Mn in all sludge samples and Pb in all tap water, Umhlathuzana River, and Northern Works influent samples. Comparable recoveries and metal concentrations were obtained by microwave and hotplate methods, suggesting that the cheaper hotplate method can be used as an effective digestion method for daily analysis. Common anion concentrations obtained ranged from 0.03–23.5 mg/L, 0.02–3 064.67 mg/L, and 0.32–175.67 mg/L for tap, river, and wastewater samples, respectively. The anion concentrations were found to be below the maximum acceptable limits indicating no negative health effect on human and aquatic life, with the exception of Cl− and SO42− in Amanzimtoti and Northern River water, respectively.

Problematic series watching and alcohol consumption among global audiences of Korean Drama in Israel and Indonesia

Korean dramas (K-dramas), with their unique characteristics, often encourage binge-watching. Moreover, the cultural norms and rituals surrounding alcohol, prevalent in South Korea, are mirrored in K-dramas that have gained global audiences in recent years. The present study aimed to examine problematic K-drama series watching, and the potential associations with alcohol consumption among global adult audiences from Israel and Indonesia. An online questionnaire was distributed to a non-probability convenience sample of 638 adult viewers of K-drama, of whom 383 (60%) were Indonesian and 255 (40%) were Israeli. Fifteen percent of the audiences were identified as displaying problematic K-drama series watching, 36% reported ever drinking Soju (the traditional unique Korean drink), 41% reported drinking alcohol in the past 3 months, and 24% reported binge drinking in the past 12 months. Participants who were higher in problematic K-drama series watching were more likely to be involved with drinking Soju, drinking alcohol in the past 3 months, and binge drinking in the last year. Indonesians and Israelis have significantly different viewing patterns and alcohol consumption. 21.2% of Israelis identified as problematic K-drama series watching compared to 10.7% of Indonesians. Greater percentage of the Israelis have reported consumption of alcohol than Indonesians. Multiple linear regression for problematic K-drama series watching revealed that Israeli audiences, younger age, being defined as a fan, being a member of a K-drama social network, higher number of weekly hours spent watching, and greater number of dramas being watched per month were associated with more problematic K-drama series watching. Series binge-watching may entail potentially negative health and social consequences and professionals should pay more attention to this type of problematic behavior. The identification of problematic K-drama series watching and its association with increased alcohol consumption, suggests the need for health policymakers to consider cultural influences on media alcohol messages consumption.

The association between continuous polypharmacy and hospitalization, emergency department visits, and death in older adults: a nationwide large cohort study.

This study aimed to investigate the association between continuous polypharmacy and hospitalization, emergency department (ED) visits, and death. This retrospective study utilized 6,443,896 patients aged between 65 and 84years of National Health Insurance claims data from 2016 to 2018. Polypharmacy and excessive polypharmacy were defined as the concurrent use of 5 or more and 10 or more medications, respectively, for durations of both 90days or more and 180days or more within a 1-year observation period. The primary outcome measures included all-cause hospitalization, ED visits, and mortality. Multiple logistic regression models were used adjusting for patients' general characteristics, comorbidities, and history of hospitalization or ED visits. Among 2,693,897 patients aged 65-84years who had used medicines for 180days or more (2,955,755 patients taking medicines for 90days or more), the adverse outcomes were as follows: 20.5% (20.3%) experienced hospitalization, 10.9% (10.8%) visited the ED, and 1% (1%) died, respectively. In patients who exhibited polypharmacy for more than 180days, the adjusted odds ratio of adverse outcomes was 1.32 (95% confidence interval [CI], 1.31-1.33) for hospitalization, 1.32 (95% CI, 1.31-1.33) for ED visits, 1.63 (95% CI, 1.59-1.67) for death, and that in excessive polypharmacy patients for more than 180days was 1.85 for hospitalization, 1.92 for ED visits, and 2.57 for death, compared to non-polypharmacy patients. Our results suggest that polypharmacy in older adults might lead to negative health consequences. Thus, interventions to optimize polypharmacy may need to be implemented.

Dutch consumers’ attitude towards industrial food processing

Industrial food processing and its possible adverse effects on health are widely debated in scientific literature and media. There is not much known about consumers’ attitudes towards the processing of foods. Therefore, a questionnaire (n = 463) was distributed and interviews (n = 11) were conducted with Dutch consumers to evaluate the attitudes and associations towards industrial food processing and to assess opinions about communications on food processing and health. The results showed that 51% of the respondents had a neutral, 23% had a positive, and 26% had a negative attitude towards food processing. Respondents with a background in food by profession or education (n = 159) had more frequently a positive attitude towards food processing (P = 0.008). Respondents and interviewees pointed out both positive and negative associations with industrial processing: additives, artificial, not fresh, low nutritional value, unnatural, but also palatability, food safety, shelf life, and convenience. The questionnaire showed that 70% of the respondents thought food processing had a (slightly) negative health effect. Most interviewees indicated that when doing groceries, food processing per se is not relevant in food choices, although some critically inspected the ingredients. Furthermore, interviewees indicated that communication about food and health is scattered and complex. They would like to gain easy and straightforward information from a central source. From the questionnaire respondents, 60% indicated that they would like to have more information about food processing. In conclusion, most Dutch consumers in this study have a neutral and nuanced attitude towards industrial food processing. A connection with food via profession or education showed a more positive attitude, which may indicate the importance of knowledge and the need for clear communication about nutrition, ingredients, and food processing.

Health risks associated with mercury intake from rice and rice products

The main route of human exposure to toxic contaminants is through the consumption of contaminated food. To protect against potential negative health effects of rice consumption, the concentration of total mercury (THg) in rice and rice products sold in Poland was determined, and a consumer risk assessment was carried out. In this study, the concentration of THg in selected types of rice and rice products was determined and assessed. The determinations were carried out using atomic absorption spectroscopy (AAS) in a DMA-1 mercury analyzer. Based on the estimated daily intake (EDI), target hazard quotient values (THQ), and tolerable weekly intake (TWI), the toxicological risk associated with the intake of total mercury and methylmercury (MeHg) from the products tested was also estimated. The analysis indicated that the highest Hg content was in rice cakes and the lowest in white rice and rice noodles. Total mercury content was found to be below the maximum permitted level. The estimated daily intake (EDI) and target hazard quotient (THQ) values for THg and MeHg in rice and rice products were lower than 1. These findings suggest that the food items examined pose no health risk.

Household e-waste management: A comprehensive review

The improper handling of domestic e-waste poses serious environmental and health risks. By highlighting the crucial problems and potential solutions, this thorough analysis attempts to synthesize the body of knowledge on managing household e-waste. However, designing sustainable management techniques requires consideration of the collection system, consumer awareness, and policy. Inadequate household e-waste management has led to resource waste, the leakage of dangerous contaminants into ecosystems, and negative health effects on humans and the environment. Using the search engine database SCOPUS, a comprehensive literature review encompassing journal articles spanning the last four years from 2019–2022 was performed. The key themes used in the review, such as collection system, awareness, and policy, were analyzed and synthesized. This review reveals the challenges in managing household e-waste. Collection mechanisms vary widely, with success relying on factors such as awareness campaigns and Deposit-Refund Schemes (DRSs). Collecting processes exhibit significant disparities in efficiency, with potential for improvement through technological advancements, such as smart sorting systems and robotics. Policy frameworks, while present in many regions, often lack comprehensive implementation. To address these challenges effectively, a holistic approach is needed. Implementing comprehensive policy frameworks, raising awareness, and adopting emerging collecting system technologies are crucial steps forward.

Investigating the relationship between shift work schedule and blood and metabolic parameters: a 10-years retrospective cohort study

Shift work has become increasingly common in modern society. Shift work has been associated with a range of negative health outcomes. Therefore, this 10-years retrospective cohort study, aimed to investigate the relationship between shift work and blood and metabolic parameters. This retrospective cohort study was conducted in a metal parts manufacturing industry in 2023. In this study, 204 shift workers and 204 day workers were examined. All the studied blood and metabolic parameters were collected by reviewing the medical records of all participants during a 10-years period (2013–2022). Moreover, the amounts of physical, chemical, and ergonomics harmful agents in the work environment were investigated. All the collected data were analyzed using SPSS version 25.0. The values of Body Mass Index (BMI), Red Blood Cell Count (RBC), Platelets Count (PLT), Thyroid-Stimulating Hormone Level (TSH), Fasting Blood Sugar Level (FBS), Creatinine, Triglyceride (TG), Liver Enzymes level (SGOT and SGPT), and Systolic Blood Pressure (SBP) were higher among the shift work employees, and a significant difference was observed between the values of these parameters between the two groups. The results of logistic regression showed that the highest effect of shift work was observed on the parameters of FBS, TG, SGPT, TSH, Physical activity, BMI, Sleep duration, PLT, and Sleep quality with beta coefficient values of 0.49, 0.33, 0.29, 0.29, 0.20, 0.18, 0.14, 0.13 and, 0.11, respectively (p-value < 0.01). The present study contributes to a growing body of evidence that blood and metabolic factors are likely to be influenced by shift work. These findings have important implications for policy makers, highlighting the need for interventions to mitigate the negative health effects of shift work on workers.

Factors underlying mothers’ decision to offer ultra-processed meals during early childhood

The growing evidence on the negative health effects of ultra-processed products indicates the need to develop strategies to discourage their consumption among infants and children. The development of such strategies requires a deeper understanding of the factors underlying children’s consumption of ultra-processed products. In this context, the present work aimed to analyze factors underlying mothers’ decision to offer meals composed of ultra-processed products during early childhood (6 months to 5 years old). An online survey with 888 mothers was conducted. Participants were shown a series of pictures of ultra-processed meals and were asked to indicate whether they would offer them to their children or not. A follow-up open-ended question was used to explore reasons underlying negative responses. A relevant proportion of mothers indicated that they would offer the ultra-processed meals to their children (48.5 % to 64.5 %). On the other hand, motives for not offering ultra-processed meals to children were mainly related to food processing and nutritional composition. Several variables of the child (age, food fussiness), the mother (education level and socio-economic status), and the household (presence of children older than 5 years) had a significant effect on the likelihood of mothers offering ultra-processed meals and mentioning different reasons for not doing so. Results stress the need to implement strategies to increase perceived risk of ultra-processed products, particularly among parents with low educational level and from low socio-economic status.

Health and equity impacts of global consultancy firms

BackgroundConcern is growing over the power, influence, and threats to health and equity from the operations of large global consultancy firms. Collectively, these firms support a neoliberal policy environment promoting business interests ahead of public health. Global consultancy firms act as commercial determinants of health, an evolving area of research over recent years. However, this research mainly focuses on specific corporations or industry sectors, especially those which produce harmful products, including ultra-processed food, alcohol, and fossil fuels. It is therefore important to expand the focus to include large global consultancy firms and place a public health and equity lens over their operations.Main bodyGlobal consultancy firms have wide-ranging conflicts of interest. These arise from the ‘revolving door’ employment strategies between their own staff and those from government and regulatory bodies. These firms also advise governments on taxation and other matters while concurrently advising corporate clients on ways to minimise taxation. They advise fossil fuel corporations while also advising governments on climate and health policies. These firms undermine the capabilities of the public sector through the outsourcing of traditional public sector roles to these private interests. Consultancy firms foster private interests through their engagement with the higher education sector, and thereby weaken the tradition of transparent management of university affairs by accountable university councils. While private consultancies cannot be blamed for all the negative consequences for health and equity caused by the problems associated with globalisation and advanced capitalism, they have played a role in amplifying them.ConclusionAddressing the negative impacts of global consultancy firms will require strengthening the public sector, enforcing greater transparency, accountability, and minimising conflicts of interest. It will also demand critical thought, counter discourses, and activism to reframe the narratives supporting neo-liberal ideas of governance that are promoted in both government and business arenas.

Occurrence of aflatoxin M1 in cheese products commonly available in Sri Lankan market

Aflatoxins (AFs) are a group of mycotoxins produced by certain fungi of Aspergillus spp. AFs of major concern are B1 (AFB1), B2 (AFB2), G1 (AFG1), G2 (AFG2), and M1 (AFM1). AFM1 is a hydroxylated metabolite of AFB1 formed inside the animal's body which is excreted into milk of cows that consumed AFB1 contaminated feed. Consumption of AFM1-contaminated milk and subsequent dairy products causes negative health effects in consumers. This study was conducted to determine the occurrence and levels of AFM1 in cheese products available in the Sri Lankan market where AFM1 is not regularly monitored in milk while having an outdated regulatory limit of 1 ppb established for dairy products. Processed cheese (n = 28), hard cheese (n = 14), semi-hard cheese (n = 5), and soft cheese (n = 3) representing seven popular brands were collected. The samples were analyzed by Ultra High-Performance Liquid Chromatography Fluorescence Detection. AFM1 was detected in 40 samples (80 %), while 17 (34 %) and 37 (74 %) of the samples had AFM1 levels exceeding the maximum permitted limit set by Codex Alimentarius Commission (0.5 ppb) and the Netherlands (0.2 ppb). Further, 10 samples violated the Sri Lankan maximum limit of 1 ppb. Thirteen out of the 14 hard cheese (92.9 %, 0.11–14.43 ppb) and all semi-hard cheese samples (100 %, 0.29–0.65 ppb) contained AFM1. Most of the soft (66.7 %, 0.35–0.45 ppb) and processed (71.4 %, 0.11–1.35 ppb) cheese samples had AFM1. Most of the locally manufactured cheese products in Sri Lankan market may pose health risks to consumers. The results highlight the significance of regular monitoring of AFM1 in dairy products and the importance of updating regulations on par with international standards concurrently to ensure consumer safety.

Polyester Microfibers Exposure Modulates Mytilus galloprovincialis Hemolymph Microbiome.

Microplastic (MP) contamination in the aquatic environment is a cause of concern worldwide since MP can be taken up by different organisms, altering different biological functions. In particular, evidence is accumulating that MP can affect the relationship between the host and its associated microbial communities (the microbiome), with potentially negative health consequences. Synthetic microfibers (MFs) represent one of the main MPs in the marine environment, which can be accumulated by filter-feeding invertebrates, such as bivalves, with consequent negative effects and transfer through the food chain. In the mussel Mytilus galloprovincialis, polyethylene terephthalate (PET) MFs, with a size distribution resembling that of an MF released from textile washing, have been previously shown to induce multiple stress responses. In this work, in the same experimental conditions, the effects of exposure to PET-MF (96 h, 10, and 100 μg/L) on mussel hemolymph microbiome were evaluated by 16S rRNA gene amplification and sequencing. The results show that PET-MF affects the composition of bacterial communities at the phylum, family and genus level, with stronger effects at the lowest concentration tested. The relationship between MF-induced changes in hemolymph microbial communities and responses observed at the whole organism level are discussed.

“I lived but I wasn’t alive”: Examining responses of formal systems to child sexual abuse as described in survivors’ testimonies to the Israeli Independent Public Inquiry

Child sexual abuse (CSA) is a prominent global issue with a multitude of negative health, social, and economic consequences. However, this abuse is often under-reported and misunderstood, alongside faults within the systems built to support CSA survivors. There has been a global effort to establish CSA inquiries investigating past incidents of CSA, using the findings to inform and reform policy and practice and pursue justice for CSA survivors. In 2020, The Israeli Independent Public Inquiry into Child Sexual Abuse was founded, collecting 505 rich, diverse, and informative testimonies from adult survivors of CSA in Israel. The current study analyzes the 505 testimonies to explore the ways formal systems of support in Israel responded to CSA survivors and how these responses impacted survivors. Inductive thematic analysis was performed, yielding three main themes: 1) displays of how formal systems failed to respond to CSA, 2) mechanisms behind the failures of formal systems in their responses to CSA, and 3) consequences of the failures of formal systems to respond to CSA. This study demonstrates the tremendous impact formal systems’ responses can have on survivors, underscoring the urgent need for a systematic change in how CSA survivors are treated. Current systems have led to the violation of children’s rights, re-traumatization of survivors, and even discouraged survivors from seeking help after abuse. This study concludes that many adaptations must be made to formal systems’ current responses to CSA in Israel to improve support for CSA survivors, advance child protection, and recognize the unique needs of minority communities.

Human cytomegalovirus in breast milk is associated with milk composition and the infant gut microbiome and growth

Human cytomegalovirus (CMV) is a highly prevalent herpesvirus that is often transmitted to the neonate via breast milk. Postnatal CMV transmission can have negative health consequences for preterm and immunocompromised infants, but any effects on healthy term infants are thought to be benign. Furthermore, the impact of CMV on the composition of the hundreds of bioactive factors in human milk has not been tested. Here, we utilize a cohort of exclusively breastfeeding full-term mother-infant pairs to test for differences in the milk transcriptome and metabolome associated with CMV, and the impact of CMV in breast milk on the infant gut microbiome and infant growth. We find upregulation of the indoleamine 2,3-dioxygenase (IDO) tryptophan-to-kynurenine metabolic pathway in CMV+ milk samples, and that CMV+ milk is associated with decreased Bifidobacterium in the infant gut. Our data indicate two opposing CMV-associated effects on infant growth; with kynurenine positively correlated, and CMV viral load negatively correlated, with infant weight-for-length at 1 month of age. These results suggest CMV transmission, CMV-related changes in milk composition, or both may be modulators of full-term infant development.

Effects of low-dose acetylsalicylic acid on the inflammatory response to experimental sleep restriction in healthy humans

BackgroundSleep deficiencies, such as manifested in short sleep duration or insomnia symptoms, are known to increase the risk for multiple disease conditions involving immunopathology. Inflammation is hypothesized to be a mechanism through which deficient sleep acts as a risk factor for these conditions. Thus, one potential way to mitigate negative health consequences associated with deficient sleep is to target inflammation. Few interventional sleep studies investigated whether improving sleep affects inflammatory processes, but results suggest that complementary approaches may be necessary to target inflammation associated with sleep deficiencies. We investigated whether targeting inflammation through low-dose acetylsalicylic acid (ASA, i.e., aspirin) is able to blunt the inflammatory response to experimental sleep restriction. Methods46 healthy participants (19F/27M, age range 19–63 years) were studied in a double-blind randomized placebo-controlled crossover trial with three protocols each consisting of a 14-day at-home monitoring phase followed by an 11-day (10-night) in-laboratory stay (sleep restriction/ASA, sleep restriction/placebo, control sleep/placebo). In the sleep restriction/ASA condition, participants took low-dose ASA (81 mg/day) daily in the evening (22:00) during the at-home phase and the subsequent in-laboratory stay. In the sleep restriction/placebo and control sleep/placebo conditions, participants took placebo daily. Each in-laboratory stay started with 2 nights with a sleep opportunity of 8 h/night (23:00–07:00) for adaptation and baseline measurements. Under the two sleep restriction conditions, participants were exposed to 5 nights of sleep restricted to a sleep opportunity of 4 h/night (03:00–07:00) followed by 3 nights of recovery sleep with a sleep opportunity of 8 h/night. Under the control sleep condition, participants had a sleep opportunity of 8 h/night throughout the in-laboratory stay. During each in-laboratory stay, participants had 3 days of intensive monitoring (at baseline, 5th day of sleep restriction/control sleep, and 2nd day of recovery sleep). Variables, including pro-inflammatory immune cell function, C-reactive protein (CRP), and actigraphy-estimated measures of sleep, were analyzed using generalized linear mixed models. ResultsLow-dose ASA administration reduced the interleukin (IL)-6 expression in LPS-stimulated monocytes (p<0.05 for condition*day) and reduced serum CRP levels (p<0.01 for condition) after 5 nights of sleep restriction compared to placebo administration in the sleep restriction condition. Low-dose ASA also reduced the amount of cyclooxygenase (COX)-1/COX-2 double positive cells among LPS-stimulated monocytes after 2 nights of recovery sleep following 5 nights of sleep restriction compared to placebo (p<0.05 for condition). Low-dose ASA further decreased wake after sleep onset (WASO) and increased sleep efficiency (SE) during the first 2 nights of recovery sleep (p<0.001 for condition and condition*day). Baseline comparisons revealed no differences between conditions for all of the investigated variables (p>0.05 for condition). ConclusionThis study shows that inflammatory responses to sleep restriction can be reduced by preemptive administration of low-dose ASA. This finding may open new therapeutic approaches to prevent or control inflammation and its consequences in those experiencing sleep deficiencies. Trial RegistrationClinicalTrials.gov NCT03377543.

The perceptions of harmfulness. Addictiveness and social acceptance of hookah smoking among adolescents in Turkey

ABSTRACT Background Hookah smoking among adolescents is a growing public health concern, potentially fueled by a lack of awareness regarding its health risks. This study aimed to determine the risk factors associated with hookah smoking and explore adolescents’ perceptions of its harmfulness, addictiveness and social acceptability. Methods Between October 2019 and April 2020, 400 adolescents aged 12 to 18 years participated in an interviewer-administered survey including socio-demographic characteristics, past medical history, lifestyle behaviors, tobacco use of adolescents and their immediate circle, knowledge on hookah’s health risks, perceptions of hookah’s addictiveness and social acceptability. Results Among adolescents 6.8% were regular hookah smokers, while 14.5% had tried hookah at least once. Adolescents who believed hookah was not addictive were more likely to perceive it as socially acceptable (p < 0.001). The perception of social acceptance increased by 1.68 times with each year of age, 2.05 times in the presence of a smoking teacher, and 10.14 times with having tried hookah once. Conclusions This study highlights that adolescents’ limited knowledge of hookah’s negative health effects and addictive nature contributes to its social acceptance. Moreover, in addition to family members and friends, teachers significantly impact adolescents’ hookah use and their perceptions of its harmfulness, social acceptability and addictiveness.

Management of socio-hygienic monitoring of the soil quality

Soil is the main factor in the preservation and accumulation of toxic compounds in nature that are resistant to the environment. Coming from the soil into adjacent environments, they lead to negative consequences for both human health and the environment. Approaches to the management of socio-hygienic monitoring of the soil quality currently require changes in the Russian Federation. During the study, normative and methodological documents regarding the conduct of socio-hygienic monitoring (SGM), forms of state sectoral reporting of the Russian Federation and the Republic of Belarus, State reports “On the sanitary and epidemiological situation in the Russian Federation” were studied, the following databases were used when conducting a literature search: Pubmed, Scopus, Web of Science, MedLine, Global Health, RSCI. During the analysis of industry reporting materials in the territories of the Russian Federation, the set of indicators for assessing the quality of soils in populated areas was revealed to be not sufficient, it does not take into account pollutants such as benz(a)pyrene. When conducting social and hygienic monitoring, a special place is also occupied by the choice of points for sampling soil for control, currently, such a significant object as landfills and landfills is not taken into account when choosing. The results of the study can only be used in the development of methodological documents for assessing the soil quality within the framework of the SGM, and are not applied to other facilities. The authors have proposed recommendations for expanding the range of indicators determined in the soil, changing the approach to managing monitoring on the ground. All this will make it possible to fully assess the possible risks to public health from the influence of soil pollutants.

Computational analysis of electromagnetic field exposure in passengers near high- current contact wire environments.

The electromagnetic environment of a railway station is composed of electrical, magnetic, and electromagnetic fields, which are generated by various sources such as traction current, voltage, pantograph-catenary arc, locomotive braking, wheel-rail rolling arc, and communication systems. However, there is public growing concern among the public about the potential negative human health effects of this electromagnetic environment. To analyze the distribution of electromagnetic fields in human tissues, electromagnetic simulation software is used to create a model that includes six track contact wires and four waiting passengers on three platforms. This model is used to analyze the magnetic field environment created by high currents in the contact wires of a multi-track high-speed railway station. By varying the loads on different contact wires, the distribution of electric field and magnetic flux density within human tissues of waiting passengers on different platforms is studied using this model. When the track is unoccupied, the calculation results show that the maximum values of the electric field and magnetic flux density of the passenger's human body tissue at the blind way on the platform and 1m of the blind way are 17.6mVm-1 and 52.7 μT, respectively. These values increase by 9.28mVm-1 and 16.4 μT compared to when the track is occupied. When more contact wires are loaded with currents, the electric field mode and magnetic flux density mode of human tissues increase at the same position on the platform. Specifically, when the contact wires of six tracks are loaded with current at the same time, the maximum values of the electric field mode and magnetic flux density mode of the waiting passengers' human tissues at the blind way on different platforms are 29.6mVm-1 and 88.1 μT, respectively. These maximum values are lower than the public electromagnetic exposure limits that are designated by the International Commission on Non-Ionizing Radiation Protection guidelines. The research results demonstrate that the magnetic field environment generated by the current in the contact wires of a railway station with six tracks does not pose a health risk to human tissues of passengers waiting at the blind way and 1m of the blind way on the platform. These findings can provide valuable data reference for the formulation of relevant standards for the design of electrified rail transit, as well as the suppression of electromagnetic interference and protection of human bioelectromagnetism.

Evaluation of the association of physical activity levels with self-perceived health, depression, and anxiety in Spanish individuals with high cholesterol levels: a retrospective cross-sectional study.

Hypercholesterolemia is the most common form of dyslipidaemia in the world leading to negative health effects, both physical and mental. Physical activity (PA) can reduce total cholesterol and has positive effects on mental health. This retrospective cross-sectional study analyses the relationships between physical activity level (PAL), self-perceived health (SPH) and mental health. This study was based on data from the Spanish National Health Survey 2017 (SNHS 2017), with 3,176 Spanish adults with high cholesterol as participants. Non-parametric tests were used as the data did not follow normality. Dependent relationships were found between PAL and SPH, depression and anxiety. Women had higher depression and anxiety prevalences than men, while men were more likely to report being very active, although the proportion of walkers was higher in women. The physically inactive population presented higher negative SPH, depression and anxiety proportions and psychological distress than physically active people. The physically inactive people had a higher risk of negative SPH, depression and anxiety. Regular PA may improve SPH and mental health in people with high cholesterol, but more studies are needed to establish causal relationships, mechanisms, and optimal doses.

Optimizing Total Knee Arthroplasty Rehabilitation With Telehealth Physical Activity Behavior Change Intervention: A Randomized Clinical Trial.

Conventional total knee arthroplasty (TKA) rehabilitation has little impact on sedentary lifestyles that have negative long-term health consequences. The purpose of this trial was to determine the effect of telehealth-based physical activity behavior change intervention on physical activity and functional outcomes following TKA. This study was a 2-arm, parallel randomized controlled superiority trial at a regional Veterans Affairs medical center. The participants were 92 US military veterans (mean age = 65.7 [SD =7.8] y) undergoing unilateral TKA. The Physical Activity Behavior Change (PABC) intervention included telehealth-based self-management training (10 30-minute sessions) delivered over 12weeks. The control intervention included telehealth-based health education sessions that matched PABC frequency and duration. Both groups participated in standardized conventional outpatient rehabilitation. Physical activity, measured as average daily step count, was the primary outcome. Secondary outcomes were Life-Space Assessment questionnaire, 30-Second Chair-Stand test, Timed "Up & Go" Test, 6-Minute Walk Test, Western Ontario and McMaster Universities Osteoarthritis Index, and Veterans RAND 12-Item Health Survey. The Self Efficacy for Exercise scale and daily time spent in different postures (sitting/lying, standing, stepping) were exploratory variables. Outcomes were measured at baseline (before surgery), mid-intervention (8weeks after surgery), after the intervention (14weeks after surgery; primary endpoint), and follow-up (38weeks after surgery). The PABC group had an estimated 931 (95% CI = 42-1819) more daily steps than the control group from baseline to 14weeks, though a between-group effect was not sustained at 38weeks. There were no group differences in secondary outcomes. Participants included only military veterans using Veterans Health Administration services. The intervention targeted self-management and did not include peer support. The PABC intervention improved physical activity for veterans recovering from unilateral TKA at 14weeks after surgery, though the effect was not sustained at 38weeks. Physical function improved with rehabilitation but was not different between groups, indicating that physical function was not a primary driver of physical activity behavior. Conventional TKA rehabilitation has a negligible effect on free-living physical activity, which is relevant to long-term health outcomes. This trial identified telehealth physical activity self-management as effective in addressing activity behaviors, separate from conventional rehabilitation strategies.

Electronic cigarettes - harmful substances contained in e-cigarette liquids and smoke

Electronic cigarettes and electronic cigarette liquids are increasingly popular in society, especially among young people. However, despite the widespread belief that they are a safe alternative to traditional cigarettes, many scientific studies confirm that electronic cigarettes can be equally, if not more, harmful to health. There are many chemicals in electronic cigarette liquids, such as nicotine, propylene glycol, glycerol, flavors and fragrances. Some of these substances are toxic and can cause a number of negative health effects, such as irritation of the respiratory tract, the onset of lung disease, neurological disorders and increased risk of cardiovascular disease. In addition, electronic cigarettes can be harmful to the environment due to the emission of toxic substances into the air and improper disposal of used batteries. Therefore, an informed approach to the use of electronic cigarettes and an understanding of the potential health risks associated with them is necessary. Further scientific research and education of the public about the harms of electronic cigarettes are key to preventing the negative consequences associated with their use.