Gas turbine power cycles are among the most important power plants, operating in higher temperatures. Their principal defect is huge waste heat, leading to lower exergetic performances in addition to higher carbon dioxide (CO2) emissions. In this regard, the current paper focuses on a new solution to solve these defects appropriately. For this purpose, a new thermal integration model is designed for a multigeneration purpose, which is able to decrease the CO2 emission intensity below zero (a negative emission solution). The designed model comprises a steam power cycle, a Kalina power cycle, a dual organic Rankine cycle, a water desalination unit plus, and a methanol production unit plus. Thus, the products include electricity, heating, fresh water, and methanol. This system is simulated in the Aspen HYSYS software and is studied from the energy, exergy, economic, and environmental standpoints. According to the results obtained from the thermodynamic analysis, it is demonstrated that the total energy and exergy efficiencies are 49.38% and 66.5%, respectively. Furthermore, the net CO2 emission intensity of the process is negative and equals − 1.036 kgCO2/kgMeOH. Eventually, according to the economic evaluation, the methanol production cost equals 0.136 $/kg, which is 90.87% lower than the renewable methanol production method.