Negative Effects Of Smoking Research Articles

The Influence of Cigarette Smoking on Various Aspects of Periodontal Health

Tobacco is one of the most important risk factors for oral diseases, including oral cancer, oral mucosal lesions and periodontal diseases. There is substantial evidence suggesting that the risk of oral diseases increases with frequent use of tobacco and that quitting smoking results in reduced risk. In this article, the influence of cigarette smoking on the periodontium will be discussed, giving importance to the effects on immune responses, alveolar bone loss, periodontal pathogens and briefly outlining the negative effects of smoking on wound healing and periodontal treatment procedures.

Physical fitness, absenteeism and workers' compensation in smoking and non-smoking police officers

Employers seek to minimize business costs by creating conditions of employment. Relying on the presumably negative effects of smoking on variables such as workers' compensation claims, absenteeism and physical fitness scores, they seek a rational basis for requirements that employees refrain from smoking. No research has been found on police officer smoking rates relating to physical fitness, and the resulting economic variables of workers' compensation claims and absenteeism rates. To compare police officer non-smoker and smoker physical fitness, absenteeism rates and workers' compensation claims. The sample included 514 officers of a metropolitan police department. A physical fitness test was administered. Smoking status, yearly absenteeism rates and workers' compensation claims were collected. Male smokers were significantly older than non-smokers. An analysis of covariance controlling for sex and age indicated that smokers had significantly (P < or = 0.05) lower fitness scores in sit and reach flexibility, sit-ups endurance, bench press strength and bicycle ergometer cardiovascular endurance. When neither age nor sex was controlled in males, a similar trend continued. However, in females only the sit and reach and sit-up tests demonstrated statistically significant differences. Fat percentage, step-test scores, absenteeism rates and workers' compensation claims were not statistically different. These data do not provide a rational basis for the requirement that officers refrain from smoking when considering body fat and the economic savings of lower absenteeism rates and workers' compensation. To some extent, smoking policies can be justified by officers' physical fitness but there are age, gender and test protocol considerations.

Sex-specific differences in birth weight due to maternal smoking during pregnancy

We investigated the sex-specific risk of maternal smoking during pregnancy on the birth weight and the proportion of small-for-gestational-age (SGA) newborns in 888,632 (49.9%) of 1,815,318 singleton births (ca. 80% of all singleton births in Germany from 1995 to 1997) in whom data on maternal cigarette consumption were available. Newborns below the 10th percentile for weight and duration of pregnancy were classified SGA. Maternal smoking during pregnancy lowers the mean birth weight and increases the risk of SGA newborns. The negative effect depends on the daily number of cigarettes consumed, and is greater in girls than in boys. In non-smokers, 9.8% of the newborns were SGA, with a sex-ratio of females:males=1, but this percentage increased with increasing number of cigarettes consumed (p<0.001), as did the sex-ratio, i.e. the negative effect of smoking on growth was greater in girls than in boys. In mild smokers (1-5 cigarettes/day), the risk of giving birth to an SGA girl was 1.7275-fold (95% CI: 1.7266-1.7284) above normal, but was 1.7143-fold (95% CI: 1.7137-1.7150) in boys. More than 21 cigarettes/day increased the risk of SGA 3.15-fold for a boy, but 3.51-fold for a girl (p<0.001). In conclusion, particularly in heavy smokers, the negative effect of maternal smoking during pregnancy on the mean birth weight and risk of SGA is significantly greater in newborn girls than in newborn boys.

Prevalence and correlates of tobacco use among Russian cancer patients: Implications for the development of smoking cessation interventions at a cancer center in Russia

This study examined the rate of smoking among 399 cancer patients in Russia and assessed correlates of tobacco use and readiness to quit smoking. The results indicated that (a) 41.6% of patients were smokers; and (b) smokers were likely to be male, have lung or colorectal cancer, exhibit low levels of knowledge concerning the negative effects of smoking, report a low level of advantages to quitting smoking and a high level of disadvantages to quitting smoking, show low perceived risk for the adverse effects of smoking, and exhibit high fatalistic beliefs. Though certain findings converge well with data collected from U.S. samples of cancer patients, these results can guide the development of smoking interventions that address the specific needs of Russian cancer patients. In sum, this study fills a critical gap in knowledge concerning the epidemic of tobacco use in Russia and broadens research regarding tobacco use by cancer patients from the United States to the Russian Federation.

Influence of smoking and snus on the prevalence and incidence of type 2 diabetes amongst men: the northern Sweden MONICA study

Influence of smoking and snus on the prevalence and incidence of type 2 diabetes amongst men : the northern Sweden MONICA study.

Clinical Correlation between the Consumption of Nicotine and Cotinine Concentrations in Urine and Serum by Competitive Enzyme-Linked Immunosorbent Assay

Different negative effects of smoking are known (e.g. postoperative complications), which lead, especially in plastic surgery, to unsatisfactory results. The aim of this study was to examine the appropriateness of a cotinine enzyme-linked immunosorbent assay (ELISA) for routine usage in operative disciplines. By correlation of smoking habits and concentration of cotinine in serum and urine, we tried to ascertain reference values for smokers, passive smokers and non-smokers. The reliability and sensitivity of the cotinine ELISA concerning nicotine exposure need to be proven. 165 (108 men, 57 women) test persons were examined by detecting cotinine in serum and urine by ELISA. The study shows a very good sensitivity, precision and reproducibility of the cotinine ELISA according to the laboratory criteria. The test shows significance of a good differentiation between smokers, passive smokers and non-smokers in urine. In serum, cotinines are excellent to differentiate between smokers and non-smokers/passive smokers. Urine and serum tests demonstrate valid and comparable results.

Smoking affects the outcome of guided tissue regeneration with bioresorbable membranes: a retrospective analysis of intrabony defects

To disclose factors that may influence the results of guided tissue regeneration (GTR) treatment in intrabony defects with bioresorbable membranes. Forty-seven intrabony defects in 32 patients were treated by means of polylactic acid/citric acid ester copolymer bioresorbable membranes. At baseline and after 1 year, the following parameters were recorded: (1) probing pocket depth (PPD), (2) gingival recession (REC), (3) probing attachment level (PAL)=PPD+REC, (4) presence/absence of plaque (PI), (5) presence/absence of bleeding on probing (BOP) and (6) intrabony component (IC) configuration (i.e. primarily presence of one, two, or three bone walls). Occurrence of membrane exposure and smoking habits were also recorded. Significance of differences between categorical variables was evaluated with McNemar's test, and between numerical variables with the t-test for paired observations. Generalized linear models were constructed to evaluate the influence of various factors on PAL gain and PPD after 1 year, including in the analysis only one defect per patient (i.e. 32 defects) chosen at random. Odds ratios were calculated using the Mantel-Haenszel method. Differences between smokers and non-smokers were evaluated by means of Pearson's chi2 and Student's t-test for non-paired observations. At baseline, a mean PPD of 8.6+/-1.1 mm and a mean PAL of 9.8+/-1.6 mm was recorded. Statistically significant clinical improvements were observed 1 year after GTR treatment. An average residual PPD of 3.7+/-1.1 mm and a mean PAL gain of 3.8+/-1.5 mm were recorded. IC configuration and exposure of the membrane did not seem to influence the results, while a negative effect of smoking on the clinical parameters was observed. Smokers gained approximately 1 mm less in PAL than non-smokers (3.2+/-1.4 versus 4.3+/-1.3, respectively; p=0.03) and had approximately seven times less chances to gain 4 mm in PAL as compared with patients who did not smoke (odds ratio: 0.15). PPD reduction was less pronounced in smokers than in non-smokers (4.5+/-0.7 versus 5.5+/-0.7, respectively; p<0.01), resulting in somewhat deeper residual PPD in smokers than in non-smokers (3.6+/-1.0 versus 3.4+/-1.1; p>0.05). Smoking impairs the healing outcome of GTR treatment of intrabony defects with bioresorbable membranes.

Effect of Smoking on Long Bone Shaft Fracture Healing

Purpose: To evaluate the effect of smoking on the union time of the long bone shaft fractures. Materials and Methods: We retrospectively analysed eighty-four patients with a long bone shaft fracture who were treated during the last four years. Patients with polytrauma, severe comminuted fracture, open fracture over grade III, ESRD or other internal diseases were excluded. In this study we separated the groups into smoking and non-smoking groups. Also we observed whether there was any significant difference in the union time and other factors such as the age, sex, fracture location and configuration, and method of fixation by using medical records and radiographs. Results: A significant difference in union time was found between the smoking group and the non-smoking group (p=0.041), especially in the tibia. The average union time was 12.541.62 weeks in the smoking group and 11.532.59 weeks in non-smoking group. There were three non-union cases in the smoking group and one in the non-smoking group. Other factors appeared to have no significant influences. The negative effect of smoking was more obvious in patients in their 5th and 6th decades with a distal tibia shaft fractures. Conclusion: It seems highly beneficial that patients be recommend to quit smoking while being treated for a fracture, because smoking prolongs the healing time.

The influence of smoking on clinical manifestation and composition of bronchoalveolar lavage in sarcoidosis

Sarcoidosis is defined as an inflammatory systemic disease; the characteristic morphological feature is the noncaseating granuloma. Typical finding in bronchoalveolar lavage (BAL) is a lymphocytic alveolitis with an increased CD4/CD8-quotient. A higher frequency of sarcoidosis in non-smokers (NS) than in smokers (S) has been reported. The influence of inhalative smoking on demographical data, lung function and results of BAL in prospectively selected patients with sarcoidosis was investigated. 111 NS (Sarcoidosis stage I/II+III 48/63) and 44 S (23/21) were included in the study. 16 patients without provable pulmonary disease (9 NS, 7 S) served as controls. Patients with sarcoidosis ware less often S than NS (28 vs. 72%, p = 0,0001) Controls 44 vs. 56%, p = 0.6 [chi(2)]). Sarcoidosis S were younger than NS (40.4 +/- 11.9 vs. 45.6 +/- 14.7 years, p = 0.009). There were no differences in the IVC (in % predicted). There was a negative effect of smoking on the course of the IVC (% predicted) with incremental age, not seen in the non smoking group (S vs. NS: r = -0.54, p = 0.001 vs. r = -0.13, p = 0.22). In BAL of Sarcoidosis S there was a lower concentration of albumin than of NS (in mg/dl), S vs. NS: 9.5 +/- 5.9 vs. 14.5 +/- 13.4, p = 0.012 and a trend to a less intensive lymphocytic alveolitis (in % of BAL-cells, S vs. NS: 29.2 +/- 21.1 vs. 34.1 +/- 18.6, p = 0.099). Influences of the smoking on the populations of T-lymphocytes could not be seen. (CD4/CD8-ratio S vs. NS 10.0 +/- 11.4 vs. 7. 2 +/- 7.1, p = 0, 25). In conclusion patients with sarcoidosis were more often NS than S. S were younger than NS. A protective effect of smoking on the course of lung function in sarcoidosis could be excluded. In the BAL S demonstrated a lower content of albumin and a trend to a less pronounced lymphocytosis and therefore a less pronounced alveolitis than NS. Influences of smoking on the distribution of the lymphocytic populations were not seen.

Cross sectional study on lung function of coke oven workers: a lung function surveillance system from 1978 to 1990

Aims: To determine the association between lung function of coke oven workers and exposure to coke oven emissions. Methods: Lung function data and detailed work histories for workers in recovery...

Maternal smoking and reduced duration of breastfeeding: a review of possible mechanisms.

To systematically review the possible mechanisms by which maternal smoking affects lactation. Databases (Medline, CINAHL, Current Contents, Psychinfo, Sociological Abstracts and the Cochrane Library) were searched for smoking and breastfeeding or infant feeding. The Journal of Human Lactation and Birth were hand-searched, searches were also conducted at NMAA's Lactation Resource Centre and references cited were located where appropriate. Articles were divided into the various ways that smoking could affect breastfeeding and were tabulated. Most studies were conducted on small samples of animals or humans; the majority were prior to 1985. Most animal studies exposed the animals to much greater levels of nicotine than those to which humans are exposed. Most studies did not examine if breastfeeding behaviour was similar in smokers and non-smokers, and did not consider that any physiological difference found could be the result of poor lactation practices, rather than the cause of poor lactation in smokers. The definition of breastfeeding infants was also problematic in many studies. The effect of smoking on oxytocin in women was only examined in one study, and no effect was found, yet a negative effect of smoking on oxytocin release is reported in the breastfeeding literature. Although there is consistent evidence that women who smoke breastfeed their infants for a shorter duration than non-smokers, the evidence for a physiological mechanism is not strong.

Lung function in older humans: the contribution of body composition, physical activity and smoking

An allometric model was used to determine the important factors related to the decline in forced expiratory volume (FEV1.0) across ages 55-86 years in independently living men and women. Measurements were available from a randomized sample of 181 men and 203 women residing in London, Ontario, Canada. The effects of height, age, sex, adiposity, fat free mass (FFM), grip strength and physical activity (PA) on FEV1.0 were assessed using an allometric model to test the hypothesis that sex differences in lung function would be due in part to sex-related differences in the aforementioned variables and would therefore be eliminated by our analysis. The following model was linearized and parameters were identified using standard multiple regression: FEV1.0 = heightβ1·FFMβ2 ·grip strengthβ3 ·PAβ4 ·exp (β0 + β5age + β6sex + β7smoking + β8%body fat)·∈. Results indicate that the amount of FFM and heavy intensity physical activity participated in by the elderly may be more important in influencing forced expiratory function than previously recognized. In addition, results from this study have confirmed the importance of age and height in the prediction of FEV1.0 and demonstrated a negative effect of smoking on lung function. Individuals with a greater FFM and physical activity level tended to be associated with an above average lung function performance. The cross-sectional rate of decline in FEV1.0 determined from our model was ≈12% per decade.

Impact of Maternal Anthropometry and Smoking on Neonatal Birth Weight

The purpose of this study was to determine the effect of maternal pre-pregnancy body mass index (BMI) and maternal smoking habits on neonatal birth weight. We reviewed 10,240 normal singleton term pregnancies between 1985 and 1995 at the University Department of Obstetrics and Gynecology, Vienna. Birth weights of infants of overweight smokers were greater than those of smokers in general and similar to birth weights of nonsmokers, but smoking did have a fetal growth-retarding effect in overweight smoking mothers. Infants of underweight mothers who increased their daily cigarette consumption during pregnancy had significantly lowest birth weight. Our results suggest that the negative effects of smoking during pregnancy cannot be mitigated by a higher pre-pregnancy BMI and/or an improved weight gain during pregnancy. Especially the infants of underweight mothers benefit from their mothers’ decision to cease smoking.

Effect of the spine practitioner on patient smoking status.

A prospective evaluation of the smoking habits of new spine patients was performed during a 4-year interval. To assess what effect the spine health care provider has on a patient's ongoing nicotine addiction. The negative effects of smoking and nicotine for the spine patient are well defined. Spine patients (N = 10,901) were queried as to their smoking habits during their new patient consultation; 3041 current smokers were identified. Data were obtained during 20,835 follow-up visits. Some of the smokers (n = 1632) were seen in follow-up visits and evaluated for their cigarette usage. Two different approaches were applied to assist the patient to stop smoking: 1) chart identification, reinforcement at each visit, continued education, written handout, practitioner assigning high priority, and 2) occasional mentioning, lower priority. The number of smokers who quit smoking was 35.6% in the high priority group versus 19.5% in the lower priority group. There was also a difference in the number of patients who decreased their smoking (67% vs. 38%). The fear that confronting a patient who smoked would cause the patient to leave the practice was not realized. Other factors that predicted successful cessation were fewer packs per day, fewer years smoking, and older age. The effect of the practitioner was independent of these other variables as determined by a logistic regression analysis. Patients will respond better if the practitioner assigns a priority and works with the patient to educate them about ways to address this particular substance abuse. Just asking about the patient's smoking status had a dramatic effect on smoking status. All spine practitioners should do all in their power to help their patients overcome their nicotine addiction.

Smoking and female infertility: a systematic review and meta-analysis.

The high prevalence of smoking among women in their reproductive years continues to be a matter of concern. The negative effects of smoking on general health are well known, but smoking may also affect fertility. The objective of the present study was to perform a systematic review of the literature to determine whether there is an association between smoking and risk of infertility in women of reproductive age, and to assess the size of this effect. In the 12 studies used for this meta-analysis, the overall value of the odds ratio (OR) for risk of infertility in women smokers versus non-smokers was 1.60 [95% confidence interval (CI) 1.34-1.91]. Studies of subfertile women undergoing in-vitro fertilization (IVF) treatment also show a reduction in fecundity among women smokers. A meta-analysis of nine studies found an OR of 0.66 (95% CI 0.49-0.88) for pregnancies per number of IVF-treated cycles in smokers versus non-smokers. Despite the potential limitations of meta-analyses of observational studies, the evidence presented in this review is compelling because of the consistency of effect across different study designs, sample size and types of outcome. However, continued reassurance is needed that the calculated overall effect is not in fact due to confounding variables.

Tobacco health warnings and smoking‐related cognitions and behaviours

To explore whether the introduction onto cigarette packs of new larger, more prominent health warnings in black on white would lead to an increase in: noticing warnings, thoughts about the effects of smoking, and consequent behaviours of not smoking a planned cigarette and/or prematurely stubbing out one already lit. In addition evidence was sought linking these effect to smoking cessation. Two national cross-sectional surveys of broadly representative samples of smokers: one about 2 weeks before the mandated introduction date of the warnings, and a follow-up 6 months later, part-way through implementation. A longitudinal subsample of smokers from the initial baseline survey was resurveyed at follow-up. In Australia, new health warnings and strengthened contents labelling of cigarette packets were mandated for cigarettes manufactured from 1 January 1995. Broadly representative samples of Australian smokers: 510 at baseline, and 512 at follow-up. Two hundred and forty-three of the baseline sample were also resurveyed. Self-report on effects of warnings and smoking cessation activity. In the cross-sectional sample at follow-up, 66% of smokers reported at least sometimes noticing the health warnings when taking out a cigarette (compared with 37% at baseline), and 14% reported they had refrained from smoking on at least one occasion as a result (compared with 7% at baseline). Not smoking as a result of noticing the (old) warnings at baseline was predictive of quitting at follow-up. Frequency of stubbing out cigarettes before they were finished as a result of thinking about smoking-related harm was not affected by the new warnings, but was predictive of making quit attempts. The new health warnings were more potent at stimulating both thoughts about negative effects of smoking and the appropriate consequent action of not smoking the planned cigarette. This is important as spontaneous rejection of cigarettes predicted subsequent cessation.

Relation between smoking and periodontal disease by oral hygiene status in Japanese factory workers.

The relation between smoking and periodontal disease as classified by the Community Periodontal Index of Treatment Needs (CPITN) code was investigated in 1,611 Japanese male factory workers in Osaka, 20-59 years of age. The Simplified Debris Index (DI-S) according to the Simplified Oral Hygiene Index was employed as an index for the quantity of dental plaque. For the items related to smoking, a self-reporting form on smoking, the number of years of smoking, and the number of cigarettes smoked was distributed prior to the oral examination. Our results indicated the following: in the group with a poor state of oral hygiene, the negative effects of smoking were evident, resulting in unhealthy periodontal tissue. We believe that this result further confirms the contention that the removal of dental plaque is most important as a prophylaxis for periodontal diseases, and public education about this negative consequence of smoking will further strengthen prophylactic measures.

Bone mineral density and hormone levels in menopausal Australian women.

To assess the relationships between bone mineral density (BMD) at the lumbar spine and femoral neck and menopausal status, age, physical variables, and lifestyle and gynecological factors. BMD and follicle-stimulating hormone (FSH), estradiol and inhibin levels were measured in 167 women born in Australia, aged 46-57 years, who had no record of receiving hormone replacement therapy. Using the premenopausal group as a baseline, the FSH level was higher in peri- and postmenopausal subjects (p < 0.0005), and estradiol and inhibin levels in the postmenopausal women were lower (p < 0.0005). Mean (+/- SE) lumbar spine and femoral neck BMD were 15 +/- 3% and 10 +/- 3% lower, respectively, in postmenopausal than in premenopausal women. Lumbar spine BMD decreased with increasing age in perimenopausal women only (p < 0.005), and femoral neck BMD decreased with increasing age in the pre-, peri-(p < 0.05) and postmenopausal women. The difference between femoral neck BMD in the pre- and postmenopausal women was explained by the difference in age between these groups, whereas for lumbar spine BMD the menopausal status was an additional determining factor. There was a negative effect of smoking on femoral neck BMD (p < 0.05) in postmenopausal women. In the perimenopausal decade the femoral neck BMD is primarily dependent on age, whereas lumbar spine BMD is dependent on both age and menopausal status.

Public health and private decisions

The violent reactions of some members of the intellectual class with regard to certain political aspects of the fight against smoking oblige us to pose the general problem of the legitimacy of centralised public health decisions. There are three sources of legitimacy for intervention by public authorities: the existence of an externality (the risk that each imposes on the other by his or her behaviour); the invisibility of the risk in the eyes of non-professionals; the technical impossibility of individual protection against the risk. The unequal distribution of risk could be a fourth criteria of legitimate public action but one can also consider inequity as an automatic consequence of the existence of one or more of the first three conditions when they concern the less educated, less affluent, and less influential. The "hygiene" period of preventive policy, at the end of the 19th Century in Europe, corresponds to the strong externalities because of the contagiousness of infectious diseases and the patient inability to treat them in the curative domain. On the other hand, the ability to appreciate the risks, reflecting significant social differences, seems inversely proportional to the expectations of individuals toward the State. The demand for the liberty to protect oneself from health risks is all the stronger when individuals have the cognitive and material means to effectively do so. The fight against smoking thus must constantly update the external negative effects of smoking and the setbacks in curing the ill that it creates.(ABSTRACT TRUNCATED AT 250 WORDS)

Effect of smoking on serum nutrient concentrations in African-American women

The relationship between current cigarette smoking and serum concentrations of vitamins C, E, and A, and of five carotenoids in human serum were examined in 91 low-income, African-American women. General linear models were used to adjust geometric mean serum concentrations of micronutrients for age, dietary and supplement intakes, total energy intake, alcohol intake, medication use, body mass index, and serum concentrations of cholesterol and triglycerides. Among smokers, serum concentrations of alpha-carotene, beta-carotene, cryptoxanthin, and lycopene averaged only 71-79% of the concentrations among nonsmokers. Mean serum concentrations of vitamins C and E and lutein/zeaxanthin were only slightly lower among smokers relative to nonsmokers, and current smokers had higher serum concentrations of vitamin A. Among current smokers, mean serum concentrations of all five carotenoids decreased with an increase in the amount smoked. The negative effect of smoking on serum concentrations of antioxidant carotenoids may pose a serious health risk in low-income populations already at higher risk for many chronic diseases.