Nanocomposite Beads Research Articles

Carboxymethylcellulose/polyacrylic acid/starch-modified Fe3O4 interpenetrating magnetic nanocomposite hydrogel beads as pH-sensitive carrier for oral anticancer drug delivery system

Colon cancer is the most usual illness and its oral therapy is an important challenge owing to the serious side effects on the digestive system. For this aim, novel interpenetrating magnetic nanocomposite hydrogel beads were designed based on starch-modified Fe3O4 NPs (St-Fe3O4). Carboxymethylcellulose/polyacrylic acid/starch-modified Fe3O4(CMC/PAA/St-Fe3O4) beads were prepared via a simple method. The prepared materials were fully characterized using different analyses. Anticancer doxorubicin hydrochloride (DOX) and 5-fluorouracil (5-FU) were individually loaded into the prepared nanocomposites by immersing in the solution of drugs to investigate their productivity as the loading of different anticancer drugs. In-vitro drug delivery study was performed in mimicking the gastrointestinal tract (GIT) circumstances to demonstrate the efficiency of the prepared carrier as an oral delivery system (ODS). The drug release study revealed that CMC/PAA/St-Fe3O4 nanocomposites could potentially prevent the release of 5-FU and DOX in the stomach acidic environment due to their pH-sensitive swelling manner, and also enhance the stability of drug dosing in the colorectal area. MTT assay showed significant cytotoxicity toward human colon cancer cell lines (SW480) for the drug-loaded nanocomposites; thus, they could potentially be administrated as an efficient carrier for anticancer ODS.

Environmentally benign hybrid nanocomposite beads for azo dye remediation via synchronized dual degradation mechanisms.

Practically, 12% of used dyes are excluded as waste in the mobile aqueous environment. Methyl orange (MO), an industrial azo dye, is known to be carcinogenic. Accordingly, this work was engaged to fabrication of a high-efficiency visible light photocatalysts based on Ag-Alginate/Chitosan-coated MgO nanocomposite beads. MgO and Ag were prepared via precipitation and γ-radiation reduction technique as a green physical one, respectively. The degradation mechanisms depended on catalytic reduction by means of sodium borohydride/Ag and photooxidative degradation. XRD proved the periclase crystalline form of MgO of size 20 nm and the formation of face-centered cubic silver crystals of size 15 nm. The degradation yield varied directly with time, MgO, and dye concentration until certain limit. Five and twenty minutes were enough to get clear solution of MO (30 and 15 ppm, respectively) while 60 min was required to achieve the same target for 60 ppm MO solution. The catalysts showed high efficiency for MO of high concentration. The incorporation of Ag into catalytic beads could support both mechanisms as it could elevate the degradation efficiency up to 50% and save the time to a great extent. Thus, this carrier fruitfully converted wastewater into an effluent that can be repaid to the water cycle with minimal strike on the ecosystem.

Laponite® clay/poly(ethylene oxide) gel beads for delivery of plant growth-promoting rhizobacteria

Hydrogels have been extensively used for crop improvement and this study presents a novel and facile synthesis method of clay nanocomposite hydrogel beads for encapsulation of plant probiotic bacteria. The nanocomposite used in the study consists of poly(ethylene oxide) and laponite clay. The hydrogel beads were prepared in a one-step synthesis technique to encapsulate five Pseudomonas strains both alone and as a consortium. The effects of this polymer nanocomposite (PNC) gel/plant growth-promoting rhizobacteria (PGPR) in various combinations were studied using Vigna unguiculata by evaluating its growth parameters. Here, significant improvement of leaf length, leaf number and shoot length could be observed for the consortium-encapsulated PNC hydrogel beads treated plants when compared with the untreated as well as single strain bacteria treated. In addition, the microbial viability studies indicated the PGPR to be stable up to 60 days within the PNC beads. The results of the study indicate great potential of the PNC beads mediated delivery of plant probiotic bacteria for the replacement of chemically synthesised and environmentally hazardous fertilisers.

Studies of near-spherical phosphor embedded epoxy-resin nanocomposite beads

Studies of near-spherical phosphor embedded epoxy-resin nanocomposite beads

Super adsorption performance of carboxymethyl cellulose/copper oxide-nickel oxide nanocomposite toward the removal of organic and inorganic pollutants.

A novel nanocomposite bead based on polymeric matrix of carboxymethyl cellulose and copper oxide-nickel oxide nanoparticles was synthesized, characterized, and applied for adsorptive removal of inorganic and organic contaminants at trace level of part per million (mgL-1) from aqueous sample. Carboxymethyl cellulose/copper oxide-nickel oxide (CMC/CuO-NiO) adsorbent beads were selective toward the removal of Pb(II) among other metal ions. The removal percentage of Pb(II) was more than 99% with 3 mgL-1. The waste beads after Pb (II) adsorption (Pb@CMC/CuO-NiO) and CMC/CuO-NiO nanocomposite beads were employed as adsorbents for removing of various dyes. It was found that Pb@CMC/CuO-NiO can be reused as adsorbent for the removal of Congo Red (CR), while CMC/CuO-NiO nanocomposite beads were more selective for removal of Eosin Yellow (EY) from aqueous media. The adsorption of CR and EY was optimized, and the removal percentages were 93% and 96.4%, respectively. The influence of different parameters was studied on the uptake capacity of Pb(II), CR, and EY, and lastly, the CMC/CuO-NiO beads exhibited responsive performance in relation to pH and other parameters. Thus, the prepared CMC/CuO-NiO beads were found to be a smart material which is effective and played super adsorption performance in the removal of Pb(II), CR, and EY from aqueous solution. These features make CMC/CuO-NiO beads suitable for numerous scientific and industrial applications and may be used as an alternative to high-cost commercial adsorbents.

Synthesis and characterization of Chitosan-sodium titanate nanocomposite beads for separation of radionuclides from aqueous radioactive waste

This paper reports development of a new nanocomposite “Chitosan-sodium titanate’ containing 50% of sodium titanate. SEM and TEM/EDS analysis confirmed formation of homogeneously dispersed un-agglomerated product. Ion exchange property of the composite is evaluated towards separation of strontium from simulated radioactive waste solution. The synthesized composite has been used in a fixed bed column for separation of strontium and 5000 bed volumes of simulated waste were decontaminated. It is inferred that the synthesized composite has potential for the separation of Sr from alkaline waste streams.

Naked-eye detection of specific DNA sequences amplified by the polymerase chain reaction with nanocomposite beads

We developed a novel nanocomposite bead system for detection by the naked eye of specific DNA sequences amplified by the polymerase chain reaction (PCR). The DNA probes, which were complementary to the target DNA, are conjugated with the nanocomposite beads. If the amplified products contained sequences complementary to the probes, the beads aggregated through sandwich hybridization. The aggregation was detectable as precipitation of the nanocomposite beads. The results were determined visually and did not require instrumental detection. The assay was sensitive enough to detect PCR products with a detection limit of 10 copies/tube for DNA templates. This technique is that all needed components are included within the initial cap, so that the risk of carryover contamination is very low. The nanocomposite bead system has broad application prospects for the detection of specific DNA sequences in biological and biomedical research.

Fabrication and luminescent studies of near-spherical phosphor embedded epoxy-resin nanocomposite beads

A facile method for feasible industrial production of long afterglow phosphor nanocomposites, in the form of small beads were developed that continuously emit visible light for >7 h to realize many innovative applications involving hard and soft surfaces. Green emitting SrAl2O4:Eu2+, Dy3+ (SRA) long afterglow phosphor was uniformly dispersed in the epoxy resin (ER) matrix in presence of organic surfactant as hardener to make phosphor-embedded viscous fluid that could then be solidified at room temperature (~25 °C) within few minutes. As ethyl alcohol (solvent) started evaporating, ethylene glycol (surfactant), which is the simplest amongst glycols, started adhering with SRA phosphor particles via van der Waals attraction. The homogeneity of dispersion strongly depends on the shape of SRA phosphor added to ER matrix and confirmed that the near-spherical is the best. The SRA phosphor–ER beads demonstrated an optimum ultraviolet (UV) excitation wavelength at 375 nm and a green-emission peak at 517 nm, where the latter one is due to the transitions from 4f65d1 to 4f7 energy levels of Eu2+ ions. The appearance of SRA phosphor–ER beads in translucent yellow-green color, bright green and green under ambient light, UV (375 nm) irradiation and in dark conditions, respectively was indicated using photoluminescence and colorimetric measurements. The SRA phosphor–ER beads exhibited highly durable, reversible and reproducible afterglow luminescence for longer durations. Photoluminescence, structural, morphological and afterglow properties of the prepared SRA phosphor–ER beads were investigated thoroughly. Moreover, these afterglow beads have several designing and crafting applications such as interior design, glowing toys, ornaments and tracking lights etc.

Batch and fixed bed column investigations of the sorptive removal of cesium ions from aqueous solutions using modified graphene-alginate nanocompositebeads

ABSTRACT Cesium radioisotopes are among the majors that are presented in liquid radioactive waste causing long-term environmental threats. The mandatory treatment of these streams is regenerative goal in which adsorption techniques are focal. Calcium alginate/graphene-sodium dodycyl sulfate (CA/GR-SDS) nanocomposite beads were synthesized/characterized and their sorption properties toward were evaluated. Beads were of amorphous nature and the essential components were detected by FT-IR. Batch and fixed-bed column studies were explored. The highest sorbed amounts were acquired within the 1st- 30 min of contact time. The pseudo 2nd-order model gave the best fitting of the experimental kinetic data. Simple thermodynamic models have been applied to the isotherm sorption data and the relevant thermodynamic parameters were determined from the graphical presentation of these models. Increasing temperature gave lower quantities of sorption capacities. The estimated thermodynamic parameters disclosed the exothermic spontaneous ease of all sorption processes where negative and quantities were gained. Curves of breakthrough from CA/GR-SDS were constructed at varied bed depths (2.0, 4.0, and 8.0 cm) and flow rates (1.0 and 2.0 mL/min). Increasing the bed depth to 8.0 cm, slower exhaustion time was observed (15.5 h). Capacities and performances of beds were increased from 24.85 to 214.46 mg/g and from 13.67 to 29.89%, respectively, by increasing bed depths from 2.0 to 8.0 cm. A fast exhaustion time were observed with increasing the flow rate to 2.0 mL/min (1.17 h).

One-step green synthesis of 2D Ag-dendrite-embedded biopolymer hydrogel beads as a catalytic reactor.

Silver (Ag) nanocrystals with a dendritic structure have attracted intensive attention because of their unique structural properties, which include abundant sharp corners and edges that provide a large number of active atoms. However, the synthesis of Ag dendrites via a simple and environmentally friendly method under ambient conditions remains a challenge. In this paper, we report a simple water-based green method for the production of biopolymer hydrogel beads embedded with Ag dendrites without using an additional reducing agent, stabilizer, or crosslinking agent. The obtained Ag dendrites exhibit a unique two-dimensional (2D) structure rather than a conventional three-dimensional structure because Ag+ ions are reduced on the surface of the solid-phase hydrogel beads and grow into crystals. Reasonable mechanisms explaining the formation of the nanocomposite hydrogel beads and the formation of 2D Ag dendrites in the hydrogel are proposed on the basis of our observations and results. The hydrogel beads embedded the 2D Ag dendrites were used as an environmentally friendly catalytic reactor, and their catalytic performance was evaluated by adopting the reduction of 4-nitrophenol to 4-aminophenol with NaBH4 as a model reaction.

Optimization and Feasibility of Alizarin Red S Retention on Iron- Loaded Cellulose Nanocomposite Bead

Iron(III) loaded cellulose nanocomposite bead, synthesized through sol-gel method, was characterized by Fourier transform infra-red spectroscopy, field emission scanning electron microscopy, energy dispersive spectroscopy, atomic force microscopy, tunneling electron microscopy, and tested for adsorptive removal of alizarin red S from aqueous solution. The influence of variables such as pH, contact time, initial dye concentration, adsorbent dose and temperature for dye retention were investigated in batch operation. The process was optimized by employing response surface methodology following full factorial and central composite design. The maximum adsorption of 97% was observed at an optimum condition of pH 3.0, dose of 2.0 gdm-3 and shaking time of 45 mins corresponding to the dye concentration of 100 mgdm-3 at 303 K. Correlation of cooperative influences of the significant variables and the extent of dye adsorption were represented by a second order polynomial equation. The mutual interactions of the significant variables were presented by 3D response surface and 2D contour plots in the design space. The adsorption was better described by Langmuir isotherm and pseudo second order kinetics. The process was spontaneous (-∆G°, 48.19 kJmol-1 ), feasible (∆S°, 0.284 Jmol -1 K-1 ) and endothermic (∆H°, 71.62 kJmol-1 ). The adsorbent can be regenerated with NaOH (10.0 × 10-2 M) and recycled for reuse, at least for five successive operations.

Carboxymethyl cellulose nanocomposite beads as super-efficient catalyst for the reduction of organic and inorganic pollutants

Carboxymethyl cellulose/copper oxide-nickel oxide (CMC/CuO-NiO) nanocomposite beads were prepared by facile, simple and environmentally friendly method. Initially, CuO-NiO was prepared and applied for the catalytic reduction of 4-nitrophenol (4-NP). The results showed that CuO-NiO demonstrate high catalytic activity toward the reduction of 4-NP to 4-aminophenol (4-AP) with a rate constant of 2.97 × 10−2 s−1. Further, CuO-NiO were well-dispersed in the polymeric matrix of carboxymethyl cellulose to prepare CMC/CuO-NiO beads. CMC/CuO-NiO nanocomposite beads were also applied to catalyze the reduction of potassium ferrocyanide (K3Fe (CN)6), 4-NP, Congo red (CR) and Eosin yellow (EY) in the presence of sodium borohydride. Experimental data indicated that CMC/CuO-NiO nanocomposite has higher catalytic activity and high rate constant compared to CuO-NiO. The rate constant found to be 6.88 × 10−2, 6.27 × 10−2, 1.89 × 10−2 and 2.43 × 10−2 for K3Fe(CN)6, 4-NP, CR and EY, respectively, using 5 mg CMC/CuO-NiO beads. FE-SEM, EDX, FTER, XRD and XPS were used to characterize the nanocomposites. CMC/CuO-NiO beads catalytically reduced up to 95–99% of K3Fe(CN)6, 4-NP, CR and EY within 40, 60, 120 and 120 s. CMC/CuO-NiO beads were found more selective for the reduction of 4-NP. The catalytic reduction performance of CMC/CuO-NiO beads was optimized by studying the influence of different parameters on the catalytic reduction of 4-NP. Hence, the effective and super catalytic performance toward the reduction of different organic and inorganic pollutants makes CMC/CuO-NiO beads a smart material and suitable for numerous scientific and industrial applications and may be used as an alternative to high-cost commercial catalysts.

One-pot synthesis of magnetic chitosan/iron oxide bio-nanocomposite hydrogel beads as drug delivery systems

ABSTRACT In this research, a novel dual-responsive supermagnetic chitosan/iron oxide nanocomposite hydrogel beads (CH/MION) was prepared using sodium tripolyphosphate (STPP) as cross linking agent. The prepared CH/MION hydrogel was systematically characterized by Fourier transforminfrared spectroscopy (FT-IR), scanning electron microscopy (SEM) X-ray diffraction (XRD), and vibrating sample magnetometer (VSM). In addition, the CH/MION hydrogel exhibits favorable swelling properties that are sensitive to pH, and external magnetic field (EMF). The drug release behavior of the prepared hydrogel under EMF, and different pHs was also studied. The obtained hydrogel showed considerable temperature, pH, and EMF sensitivity for the in vitro release of Doxorubicin (DOX).These results suggested that the CH/MION hydrogel beads could be a promising candidate for drug delivery applications.

Degradation of n-hexanoyl homoserine lactone with quorum quenching bacteria immobilised magnetic nanocomposite beads

ABSTRACT N-acyl homoserine lactones (AHLs) based quorum sensing controls various phenotype expressions, including biofilm formation, hence its interruption is considered to be an ideal option for membrane biofouling control. Bead entrapped quorum quenching bacteria was reported to be an efficient approach for degradation of signal molecules in recent years. In the present study, we investigated the potential of quorum quenching (QQ) bacteria immobilised magnetic nanocomposite beads (IMN) in degradation of signalling molecule, n-hexanoyl homoserine lactone (C6-HSL). Three QQ bacteria, named Acinetobacter baumannii JYQ2, Pseudomonas nitroreducens JYQ3 and Pseudomonas JYQ4 isolated from dairy industry waste activated sludge (WAS) were immobilised in the magnetic nanocomposite (IMN) beads. The scanning electron microscopy (SEM) of the IMN beads has indicated the successful entrapment of QQ bacteria within the alginate matrix. The GC-MS analysis showed that all the QQ bacteria immobilised magnetic nanocomposite (IMN) beads degraded the signalling molecule, n-hexanoyl homoserine lactone (C6-HSL) within 72 h of incubation. The nanocomposite beads containing the QQ bacteria Pseudomonas JYQ4 showed the maximum degradation percentage of 97 ± 0.13% leaving a residual HSL of 0.7 mg/L. All the other isolates showed C6-HSL degradation percentage in the range of 87% to 95%. The data suggest the potential of C6-HSL degradation by QQ bacteria IMN beads. Hence, the study offers possibilities of controlling biofilm developed on the membrane surface during wastewater treatment processes.

Response Surface Optimization of Graphene Oxide-Reinforced Dual-Crosslinked Alginate/Poly(Vinyl Alcohol) Hydrogel Beads for Methylene Blue Adsorption

Response surface methodology (RSM) was used to determine the optimal blend of alginate (ALG), poly (vinyl alcohol) (PVA) and graphene oxide (GO), as well as glutaraldehyde (GA) crosslinking solution concentration for the synthesis of dual-crosslinked ALG/PVA/GO nanocomposite hydrogel adsorbent beads for methylene blue (MB) removal. Statistical analyses show that PVA concentration contributes the largest effect to the adsorption capacity response, attributed to improved accessibility of MB molecules to adsorption sites. The optimal blend was determined to be 3% polymer with 50% PVA, 383.8384 ppm GO, crosslinked in 1% CaCl2 and 5% GA. These results were validated, and the experimental value of the adsorption capacity deviated by only 1.702% from the RSM model prediction, suggesting good model predictability. Adsorption isotherm models were tested to provide a description of the adsorption process. The Sips isotherm model, suggesting monolayer adsorption over heterogeneous surface with action of cooperative adsorbate-adsorbate interactions, was the best fit to the experimental equilibrium data, with an R2 of 0.9782. Furthermore, the ALG/PVA/GO beads demonstrated a maximum monolayer adsorption capacity of 1081.62 mg/g, showing superior performance compared to known biosorbents of MB.

Synthesis and application of chitosan/tripolyphosphate/graphene oxide hydrogel as a new drug delivery system for Sumatriptan Succinate

This study investigated the performance of chitosan-graphene oxide nanocomposite for the controlled release of the Sumatriptan Succinate (SS) drug. Various analytical methods (i.e., SEM, TEM, AFM, TGA, XRD, and FT-IR) were used to characterize the crystalline structure, molecular structure, and morphology of the fabricated nanocomposites. The effective parameters, including pH, adsorbent amount, temperature, and contact time, on the adsorption of SS on nanocomposite, were optimized. The adsorption mechanism was determined as Langmuir isotherm (R2 = 0.9976), representing the monolayer adsorption with the highest adsorption capacity of 45.4 mg/g. The addition of GO resulted in a noticeable increase (100%–200%) in the swelling degree and a decrease in drug release rates (20%- 45%) of the fabricated nanocomposites compared with the chitosan hydrogel. As the percentage of GO in hydrogel beads increases, drug release occurs less rapidly and in a controlled manner. Eventually, antibacterial activity and cytotoxicity of the prepared nanocomposite beads were evaluated, which confirmed their antibacterial properties and biocompatibility.

The effect of Ag and clay nanoparticles on the antimicrobial activity of gamma-irradiated alginate/pectin beads

In spite of the intensive work done on the preparation, characterization and applications of silver nanoparticles, the problems limit its use, still under study. One of these solutions is embedding Ag NPs in natural polymers to decrease aggregation, control its toxicity and size, and to increase its stability as well. In this respect, ionically cross-linked alginate/pectin (ALG/PEC) beads containing silver and clay nanoparticles, with different compositions were prepared. Silver nanoparticles have been obtained with hydrogel networks as nonreactors via in situ reduction of pre-adsorbed silver ions onto (ALG/PEC) beads matrix, using gamma irradiation. The effects of the composition of the two polymers, concentration of CaCl2 as a crosslinking agent on the formation of cross-linked beads were studied. Characterization of (ALG/PEC) beads, (ALG/PEC)/Ag and (ALG/PEC)/Clay-Ag nanocomposite beads were performed using scanning electron microscopy, transmission electron microscopy and X-ray diffraction (XRD). The XRD pattern obtained confirmed the presence of diffraction peaks related to Ag NPs and nanoclay. The antimicrobial activity, toward different micro-organisms of the prepared nanocomposite beads was examined. The Beads containing both Ag NPs and Nanoclay exhibited the highest antimicrobial activity for the different organisms chosen for the antimicrobial test.

MOF-based polymeric nanocomposite beads as an efficient adsorbent for wastewater treatment in batch and continuous systems: Modelling and experiment

Herein, a novel polymeric nanocomposite based on zeolitic imidazolate frameworks (ZIFs) was synthesized through a facile one step phase inversion (PI) technique. The prepared PES/ZIF-8/ZIF-67 was employed to remove Malachite green (MG) dye from colored wastewater in both batch and continuous flow systems. The influence of different parameters such as adsorbent dosage, initial MG concentration and solution pH were investigated and the results indicated that the pure PES beads had negligible adsorption, while compositing of this polymer with ZIFs particles removed 99.2% of MG molecules with a significant adsorption capacity (613.2 mg/g). Aromatic–aromatic interactions (π-π stacking) between the rings of imidazole ligand and MG dye was dominant adsorption mechanism. Kinetics and equilibrium isotherms studies revealed that batch adsorption experiment followed pseudo-second order and Langmuir models, respectively. In addition, the continuous separation process was evaluated and the breakthrough curves (BTCs) proposed that the longest breakthrough time could be attained within 12 mg/L of inlet MG concentration, 6 cm of fixed bed height and 1 mL/min of flow rate. Several well-known models including Thomas, Bed Depth Service Time (BDST), Adams-Bohart and Yoon-Nelson models were employed to correlate the experimental data obtained from the fixed bed adsorption setup. Moreover, continuous flow adsorption was simulated using Aspen Adsorption™ software which can solve the governing differential equations and provide useful information for designing and scaling up the adsorption process to the industrial levels. Consequently, the PES/ZIF-8/ZIF-67 beads with a high adsorption performance have a good application potential for eliminating organic contaminates from wastewater.

Self-Assembled Supramolecular Hybrid Hydrogel Beads Loaded with Silver Nanoparticles for Antimicrobial Applications.

This Full Paper reports the formation of silver (Ag) NPs within spatially resolved two‐component hydrogel beads, which combine a low‐molecular‐weight gelator (LMWG) DBS‐CONHNH2 and a polymer gelator (PG) calcium alginate. The AgNPs are formed through in situ reduction of AgI, with the resulting nanoparticle‐loaded gels being characterised in detail. The antibacterial activity of the nanocomposite gel beads was tested against two drug‐resistant bacterial strains, often associated with hospital‐acquired infections: vancomycin‐resistant Enterococcus faecium (VRE) and Pseudomonas aeruginosa (PA14), and the AgNP‐loaded gels showed good antimicrobial properties against both types of bacteria. It is suggested that the gel bead format of these AgNP‐loaded hybrid hydrogels makes them promising versatile materials for potential applications in orthopaedics or wound healing.

Synthesis and Characterization of Water-Based Epoxy-Acrylate/Graphene Oxide Decorated with Fe3O4 Nanoparticles Coatings and Its Enhanced Anticorrosion Properties

ABSTRACT In this article, water-based epoxy–acrylate (EP/AC) emulsion coatings and its nanocomposites with Fe3O4 nanoparticles, graphene oxide nanosheets and graphene oxide which was decorated with Fe3O4 nanoparticles were synthesized. This was executed by means of a pre-emulsion seeded semi-batch emulsion polymerization handle with a blend of conventional anionic surfactant (Polyalkylene glycol ether sulfate, ammonium salt-EXOSEL 20 S) and typical nonionic type emulsifier (Octylphenol polyoxyethylene ether OP-10) for emulsion polymerization (schematic 1). Prepared nanoparticles were investigated with different analyzing methods like FT-IR, XRD, SEM-EDAX and TGA. The impact of the distinctive nanostructures in an (EP/AC) resin, on coated steel panels with the features of corrosion conservation, was investigated by the test of electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization. Morphology of surface and thermal behavior of nanocomposite tests were executed using surface filtering electron microscopy (FE-SEM) and thermal gravimetric analysis (TGA). Different analyses resulted from nanostructures and nanocomposites approved very good dispersion of fillers in nanocomposite beads. Besides, they indicate the effective role of nanoparticles especially graphene oxide which was decorated with Fe3O4 nanoparticles in corrosion resistance of water-based EP/AC coatings and other properties of coated instances.