Mutual Link Research Articles

Right frontal cingulate cortex mediates the effect of prenatal complications on youth internalizing behaviors

Prenatal and perinatal complications represent well-known risk factors for the future development of psychiatric disorders. Such influence might become manifested during childhood and adolescence, as key periods for brain and behavioral changes. Internalizing and externalizing behaviors in adolescence have been associated with the risk of psychiatric onset later in life. Both brain morphology and behavior seem to be affected by obstetric complications, but a clear link among these three aspects is missing. Here, we aimed at analyzing the association between prenatal and perinatal complications, behavioral issues, and brain volumes in a group of children and adolescents. Eighty-two children and adolescents with emotional-behavioral problems underwent clinical and 3 T brain magnetic resonance imaging (MRI) assessments. The former included information on behavior, through the Child Behavior Checklist/6-18 (CBCL/6-18), and on the occurrence of obstetric complications. The relationships between clinical and gray matter volume (GMV) measures were investigated through multiple generalized linear models and mediation models. We found a mutual link between prenatal complications, GMV alterations in the frontal gyrus, and withdrawn problems. Specifically, complications during pregnancy were associated with higher CBCL/6-18 withdrawn scores and GMV reductions in the right superior frontal gyrus and anterior cingulate cortex. Finally, a mediation effect of these GMV measures on the association between prenatal complications and the withdrawn dimension was identified. Our findings suggest a key role of obstetric complications in affecting brain structure and behavior. For the first time, a mediator role of frontal GMV in the relationship between prenatal complications and internalizing symptoms was suggested. Once replicated on independent cohorts, this evidence will have relevant implications for planning preventive interventions.

Economic Development and Renewable Energy Nexus in Morocco

Purpose The present study explores the causal relationships between economic development, renewable energy consumption, nonrenewable energy consumption, and CO2 emissions in the context of Morocco. Methods The panel unit root test, Auto Regressive Distributed Lag (ARDL), and bounds test were used to assess the co-integration of the variables in the study and the long-run relationship between them. It employs the Granger causality test using a vector error correction model to determine the existence and direction of causality among the variables. It uses Morocco's annual statistical data from 1990 through 2019. Results The co-integration of the variables in the study was confirmed, implying that a long-run relationship exists between them. The causality test results suggest that a bidirectional causality exists between renewable energy consumption and economic development, which validates the feedback hypothesis of the mutual link between renewable energy consumption and economic development. Implications These findings suggest that Morocco's economic development is critical in providing the required resources for sustainable development. It also implies that boosting renewable energy utilization would enhance Morocco's economic development and limit environmental degradation.

Elevated erythroferrone distinguishes erythrocytosis with inherited defects in oxygen-sensing pathway from primary familial and congenital polycythaemia.

Congenital erythrocytoses represent a heterogenous group of rare defects of erythropoiesis characterized by elevated erythrocyte mass. We performed molecular-genetic analysis of 21 Czech patients with congenital erythrocytosis and assessed the mutual link between chronic erythrocyte overproduction and iron homoeostasis. Causative mutations in erythropoietin receptor (EPOR), hypoxia-inducible factor 2 alpha (HIF2A) or Von Hippel-Lindau (VHL) genes were detected in nine patients, including a novel p.A421Cfs*4 EPOR and a homozygous intronic c.340+770T>C VHL mutation. The association and possible cooperation of five identified missense germline EPOR or Janus kinase 2 (JAK2) variants with other genetic/non-genetic factors in erythrocytosis manifestation may involve variants of Piezo-type mechanosensitive ion channel component 1 (PIEZO1) or Ten-eleven translocation 2 (TET2), but this requires further research. In two families, hepcidin levels appeared to prevent or promote phenotypic expression of the disease. No major contribution of heterozygous haemochromatosis gene (HFE) mutations to the erythrocytic phenotype or hepcidin levels was observed in our cohort. VHL- and HIF2A-mutant erythrocytosis showed increased erythroferrone and suppressed hepcidin, whereas no overproduction of erythroferrone was detected in other patients regardless of molecular defect, age or therapy. Understanding the interplay between iron metabolism and erythropoiesis in different subgroups of congenital erythrocytosis may improve current treatment options.

Economic Value Added (EVA) And its Calculation Features in Banks

As a financial organization each commercial bank in order to solve its tasks, must perform a number of operations that play a primary role not only in the bank's activities, but also in the development of the economy as a whole and its individual industries. The effectiveness of corporate governance and the use of resources directly affect the economic development of the country, providing a positive financial result. Therefore, the analysis of the bank's financial indicators is especially important for management to maintain the stability of the company and increase its market share (AL Osaimi, 2019). The passive operations of Ardshinbank CJSC, considering possible scenarios for their change, are analyzed in the given article. The goal is to identify what additional economic value the bank creates and how attractive it is from the investors’ point of view. Forecasts of EVA components for 2023 have been implemented in Excel, using the tools of Polynomial and Exponential Trend line. The impact of the given components on EVA have been considered, and the bonus plan system based on the EVA indicator for managers has been calculated, which will greatly stimulate the use of the EVA indicator in banks. A regression model has been performed to identify the mutual link between the EVA indicator and the Bonus plan. The latter can become quite an interesting tool for bank managers in management decision-making.

Coevolution between Terraced Landscapes and Rural Communities: An Integrated Approach Using Expert-Based Assessment and Evaluation of Winegrowers’ Perceptions (Northwest Piedmont, Italy)

Terraced landscapes are characterized by many features but are also threatened by abandonment, with the loss of the historical landscape and increased hydrogeological risk. In this research, we developed an innovative integrated approach using expert-based assessment and evaluation of winegrowers’ perceptions to investigate the coevolution between terraced landscapes and rural communities. The aims were as follows: (i) to identify the historical landscape elements, (ii) to identify the landscape dynamics, and (iii) to analyze winegrowers’ perceptions about the historical landscape elements and future development prospects. The methodology was applied to a terraced vineyard landscape (545 ha) located in Piedmont (Italy). The expert-based assessment included historical analyses and field surveys. To evaluate winegrowers’ perceptions, an online questionnaire was used to understand their perceptions about the landscape’s historical elements and dynamics. The results suggest that unique historical landscape elements and traditional practices (vine pergolas supported by stone columns) are conserved in the area, but also highlight some dynamics, including new vine-breeding techniques (espaliers) and new land uses (olive groves, meadows, and woodland). Winegrowers (n = 49) recognized as identity elements the same identified as historical by experts. Regarding future prospects, almost all winegrowers preferred the conservation of vineyards and pergolas. The research methodology was able to show the mutual link between terraced landscapes and rural communities in coevolutionary terms and could be replicated in similar contexts. According to the winegrowers’ awareness, future planning strategies will have to support dynamic conservation of the landscape.

Oil Production and Carbon Emissions: Spline Analysis of Relationships

Obviously, the dynamics of carbon dioxide emissions depends on the volume and structure of consumption of primary energy resources in the economy. The world’s energy consumption shows a growth trend temporarily interrupted during times of economic crisis. The most noticeable decrease in energy consumption in modern history occurred in 2020, which was due to a decline in business activity in the world due to the COVID-19 pandemic. This caused a decrease in carbon emissions (by more than 6% compared to 2019). In the structure of primary energy sources, the largest reduction was in oil consumption. The paper examines the impact of economic crises on the evolution of the mutual link between the dynamics of oil production and carbon dioxide emissions in the world. To detect correlations in local time regions, it is proposed to interpolate process dynamics with cubic splines. Using this toolkit avoids the limitations of classical econometrics on the length of time series. The differentiability of the built spline models allowed us to move on to identifying and analyzing latent correlations in fluctuations in the instantaneous growth rate of oil production volumes and carbon emissions.

Links between macrophages in perivascular adipose tissue and arterial wall: a role in atherosclerosis initiation?

Inflammation of adipose tissue in relation to atherosclerosis is currently widely studied in patients with advanced disease. However, data regarding polarization of adipose tissue and arterial wall macrophages and their mutual link in the early stages of atherosclerosis are scarce. The main aim of this cross-sectional study was to characterize macrophage subpopulations in arterial wall and adjacent adipose tissue; and to determine links between different subpopulations in a relatively healthy population living kidney donors. The presence of cardiovascular risk factors was established in 68 living kidney donors. Macrophage polarization was analyzed by flow cytometry and confirmed by RT-PCR in samples of visceral adipose tissue, renal artery and adjacent perivascular adipose tissue collected during hand-assisted retroperitoneoscopic nephrectomy. CD14+CD16+CD36high macrophages were found only in adipose tissues and were strongly positively associated with several cardiovascular risk factors. The CD14+CD16+CD36low subpopulation was positively associated with the presence of several cardiovascular risk factors to a lesser extent in all studied tissues. In contrast, the proportion of CD14+CD16-CD36low macrophages was negatively linked to several cardiovascular risk factors and increased in subjects on statin therapy. The proportion of CD14+CD16+CD36low macrophages in perivascular, not visceral adipose tissue was associated with that of both macrophage subtypes in the arterial wall, suggesting a direct link between perivascular adipose tissue and the arterial wall. We confirmed the association of three macrophage subtypes in adipose tissue and arterial wall to the studied cardiovascular risk factors. Macrophage polarization in perivascular, but not visceral adipose tissue was linked to macrophage polarization in the arterial wall.

Compensative movement ameliorates reduced efficacy of rapidly-embodied decisions in humans

Dynamic environments, such as sports, often demand rapid decision-making and motor execution. The concept of embodied decision refers to the mutual link between both processes, but little is known about how these processes are balanced under severe time constraints. We address this problem by using a baseball-like hitting paradigm with and without Go/No-go judgment; participants were required to hit (Go) a moving target in the strike area or not to hit (No-go) other targets. We found that Go/No-go judgments were effective with regard to task performance, but efficacy was lost below the time constraint of 0.5 seconds mainly due to a reduction in judgment accuracy rather than movement accuracy. However, either slowing movement initiation in Go trials or canceling the movement in progress in No-go trials improved judgment accuracy. Our findings suggest that embodied decision efficacy is limited in split-second periods, but compensation is possible by changing ongoing movement strategies.

Nexus between energy poverty and economic vulnerability: Evidence from low and middle income economies

ABSTRACT Energy poverty is one of the important facets of sustainable development, but less attention to the linkage of energy poverty to economic vulnerability. This study proposes that two variables would have a mutual linkage, which is tested through a sample of 73 low- and middle-income economies. By applying panel Granger causality and two-step system generalised method of moments estimate to a system equation of two variables, the robust results are as follows. First, mutual causalities between economic vulnerability and energy poverty are evidenced. Second, economic vulnerability appears to have an increased influence on energy poverty; and energy poverty, in return, shows similar effects on economic vulnerability. Third, the nexus is mostly consistent in 46 low- and lower-middle-income economies and 27 upper-middle-income economies. The results indicate the important mutual link between economic vulnerability and energy poverty at a global level, which demands urgent action on appropriate policies to deal with energy poverty

NEGATIVE IMPACTS FROM DISRUPTION OF ROAD INFRASTRUCTURE ELEMENT PERFORMANCE ON DEPENDENT SUBSYSTEMS: METHODOLOGICAL FRAMEWORK

The critical infrastructure system is determined by subsystems essential for the functioning of the state (such as energy, transport, and emergency services). Disruption to the function of these subsystems would have serious effects on state security, the state economy, and the provisioning of the inhabitants’ basic human needs. Links connect these subsystems (i.e., sectors, subsectors, and elements), and these links ensure that certain subsystems are integrated into each other. Their interactions are derived from the type and intensity of the mutual link. The interlinked subsystems can thus be divided into influencing and dependent ones. The aforementioned mutual links in the critical infrastructure system allow, amongst other things, the spread of impacts of disruptive events amongst the subsystems via cascading effects. Disruptions to the performance of an influencing subsystem may have negative effects on a dependent subsystem, resulting in the spread of cascading effects in the critical infrastructure system. Such effects are often difficult to predict, which reduces the responsiveness of the dependent subsystems. Road transport is one of the most significant influences on critical infrastructure subsystems. For this reason, the article focuses on an indication of the negative effects of disruption of road infrastructure elements on dependent subsystems. The article describes the role of road infrastructure in the context of the critical infrastructure system. Defines the dependent subsystems of road infrastructure, categorises the negative effects, and presents a possible approach to assessing the adverse effects of disruption road infrastructure performance on dependent subsystems.

Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional Viewpoint.

Simple SummaryDysbiosis, which is an imbalance of gut microbial composition and function, can be caused by several external as well as internal factors, contributing to the onset of human and animal disorders, not limited to the gastrointestinal tract. Accordingly, the mechanisms leading to disease development involve a crucial interaction between the gut microbiota, their metabolic products, and the host. The expanded endocannabinoid system, also known as the “endocannabinoidome”, includes endocannabinoids (e.g., anandamide) and endocannabinoid-like mediators (e.g., palmitoylethanolamide), their receptors and metabolic enzymes. Dysregulation of this newly recognized endogenous system is also involved in several diseases. It is becoming increasingly apparent that a link between the endocannabinoidome and the gut microbiome exists. Here, we review some of the latest discoveries related to the functional link between these two complex systems and the disorders emerging from the malfunctioning of such a mutual interaction: for example, idiopathic inflammation, chronic enteropathies, metabolic disease and certain neuroinflammatory disorders. It is expected that in the near future new nutritional tools will emerge based on the expanding knowledge in this cutting-edge field.There is growing evidence that perturbation of the gut microbiome, known as “dysbiosis”, is associated with the pathogenesis of human and veterinary diseases that are not restricted to the gastrointestinal tract. In this regard, recent studies have demonstrated that dysbiosis is linked to the pathogenesis of central neuroinflammatory disorders, supporting the existence of the so-called microbiome-gut-brain axis. The endocannabinoid system is a recently recognized lipid signaling system and termed endocannabinoidome monitoring a variety of body responses. Accumulating evidence demonstrates that a profound link exists between the gut microbiome and the endocannabinoidome, with mutual interactions controlling intestinal homeostasis, energy metabolism and neuroinflammatory responses during physiological conditions. In the present review, we summarize the latest data on the microbiome-endocannabinoidome mutual link in health and disease, focalizing the attention on gut dysbiosis and/or altered endocannabinoidome tone that may distort the bidirectional crosstalk between these two complex systems, thus leading to gastrointestinal and metabolic diseases (e.g., idiopathic inflammation, chronic enteropathies and obesity) as well as neuroinflammatory disorders (e.g., neuropathic pain and depression). We also briefly discuss the novel possible dietary interventions based not only on probiotics and/or prebiotics, but also, and most importantly, on endocannabinoid-like modulators (e.g., palmitoylethanolamide) for intestinal health and beyond.

Culture, politics, and identity in India

ABSTRACT The present article attempts to understand the shifting configurations between culture and identity and its implications on polity and society in India. Conventional notions of unity and diversity are questioned along with emergence of identity politics. The resurgence of ‘identity politics’ tears apart the deep rooted cultural fabric along with voices to the ethnic, gender, minority and caste groups in India. This article addresses the problems in culture, politics, and identity and the linkages between them to unfold various facets of identity formation process. It intends to take up two interconnected arguments: one, which explores rather theoretically the mutual link between culture and identity; the other substantiates the link through analyzing their relationship and implications on social structure in the Indian society.

ACADEMIC VIRTUE AND ACADEMIC LEADERSHIP

the work contains substantiation of a mutual link between academic virtue and academic leadership. The reasons for academic virtue violation by applicants for higher education have been analyzed, and the main areas of working with them have been determined. These areas include motivating them regarding observing the academic virtue requirements and acquisition of corresponding values; teaching the culture of academic virtue; the control of observing the academic virtue principles in practice.

Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease

Existing studies have revealed that microRNAs (miRNAs) have a role in cognitive deficits in Alzheimer’s disease (AD). However, the function and pathophysiological mechanism of deregulated miRNAs underlying AD pathology remain to be investigated. The present study aimed to clarify the role and mechanism of miR-148a-3p in AD. RNA sequencing, qRT-PCR, and western blot analysis were used to identify the aberrant expression and signaling of miR-148a-3p within cells, mice, and patients with AD. Molecular biology techniques involving luciferase reporter assays, gene overexpression and silencing, chromatin immunoprecipitation, and adeno-associated virus-based miRNA overexpression were used to explore the biological function and mechanisms of miR-148a-3p. Downregulation of miR-148a-3p was identified in AD. Upregulation of miR-148a-3p was found to protect neuronal cells against Aβ-associated tau hyperphosphorylation by directly targeting p35/CDK5 and PTEN/p38 mitogen-activated protein kinase (MAPK) pathways. A mutual regulatory link between miR-148a-3p and PTEN using a feedforward arrangement was confirmed via promotion of transcription and expression of miR-148a-3p by way of the PTEN/Akt/CREB pathway. Significantly, in vivo targeting of miR-148a-3p signaling ameliorated cognitive deficits by decreasing p35/PTEN-elicited tau hyperphosphorylation, accompanied by feedforward transduction of the PTEN/Akt/CREB pathway. In conclusion, the present study implicated the miR-148a-3p/p35/PTEN pathway as an essential contributor to tau hyperphosphorylation and feedforward regulation in AD.

The impact of sales controls on manufacturers’ agents’ tactical decisions: the importance of inter-organizational climate

PurposeOrganizational climate is an essential dynamic to leverage in salesforce performance. This study aims to develop a model that explores the determinants of independent manufacturers’ representatives’ (i.e. IMRs’) intentions to comply with their principals’ requests for additional tasking. Using agency theory, the authors explore the application of behavior and outcome-based controls upon dyadic manufacturer-IMR relationships for these additional performance/task requests.Design/methodology/approachData from over 1,000 US-based IMRs were used to test two constructs; inter-organizational climate and perceptions of mutual satisfaction within the agency-principal dyad. Compliance behaviors tested were IMRs’ intentions to engage in non-selling-related tasks and intentions to allocate additional selling time to principals’ products. The following four exogenous controls were tested: perceived goal congruence between IMRs and principals; IMRs’ perceptions of principals’ expertise; mutual communications between IMRs and principals in the supply chain dyad; resources and sales support programs provided by principals to IMRs; and IMRs’ perceptions of the adequacy and fairness of the principals’ compensation plans.FindingsTwo constructs – inter-organizational climate and perceptions of mutual satisfaction with the agency-principal dyad – mediated the effects of exogenous sales controls on two compliance behaviors. The model’s data were analyzed using Partial least squares structural equation modeling (PLS-SEM). A marker variable was deployed to check for common method variance also supported using the Partial least squares (PLS) factor solution. Most variables demonstrated significant direct and mediated effects on each compliance behavior. Variables that emphasized behavioral-based controls dominated intentions for IMRs to engage in non-selling tasks. The principal commission structure, the only sales outcome-based control in the study, most influenced IMRs’ intentions to commit additional sales time to their principals’ products.Research limitations/implicationsThis study only examined the intentions of IMRs to engage in additional selling activities and their intention to engage in non-selling tasks. Principals may desire longer-term commitments from IMRs. The model developed here can be modified to capture additional behavioral and attitudinal outcomes including, for example, the exit intentions of IMRs.Practical implicationsPrincipals are well-advised to foster a positive inter-organizational climate that fuels perceptions of mutually satisfying working relationships with their IMRs. These mutually satisfying working relationships can, by themselves, positively influence IMRs to acquiesce to reasonable requests made by principals. This advice appears to be particularly crucial when asking IMRs to engage in additional non-selling tasks. The total pattern of path estimates points to the conclusion that capable sales control plays an important role in fostering positive inter-organizational climates. The inter-organizational climate – mutual satisfaction link proved crucial as a mediator of the impact of sales controls on IMRs’ behavioral compliance intentions.Originality/valueKnowing the impact of sales controls on IMR’s affords businesses the ability to use these controls for behavioral compliance intentions on non-selling tasks.

The pre-reflective roots of the madeleine-memory: a phenomenological perspective

This paper investigates the madeleine-memory (so-called from Proust's novel In Search of Lost Time) as a case of pre-reflective experience, from the genesis of its sedimentation into the body. Indeed, I aim to address the question of the literary protagonist Marcel on the roots of his happiness and the genesis of his memories. Until now, the madeleine-memory has been described as bodily and involuntary. In phenomenology, a wide literature has confirmed the relationship between the sense of body ownership and pre-reflective self-awareness. I aim to build upon such a mutual link and show that the pre-reflective roots of the madeleine-memory have to be traced back to the genesis of the involuntary recollections. To this purpose, I will illustrate that the epistemological relationship between the object and the subject plays a relevant role in the way the subject remembers. First, I will present that madeleine-memory is a unique case of bodily memory, by analyzing the main features that characterize it. Secondly, I will analyze the original experience of the madeleine within the phenomenological logic of transcendence in immanence. For this aim, I will rely on the Husserlian notions of “epistemological inadequacy of perception” and “background experiences”. Through these notions, I will show that Proustian involuntary recollections are pre-reflective experiences because previously subjects have pre-reflectively experienced the content of recollections.

Erythropoietin Concentration in Boys With p.His63Asp Polymorphism of the HFE Gene.

The molecular mechanism that regulates iron homeostasis is based on a network of signals, which reflect on the iron requirements of the body. HFE-related hemochromatosis is characterized by excessive intestinal absorption of dietary iron, in particular cases resulting in pathologically high iron storage in tissues and organs. During childhood, HFE gene homozygosity or heterozygosity manifests exclusively in the form of biochemical abnormalities. Because of their mutual link, bioavailable iron and endogenous erythropoietin (EPO) are indispensable for effective erythropoiesis. We analyzed the impact of p.(His63Asp) polymorphism of the HFE gene on erythropoiesis taking into consideration endogenous EPO production in the developmental age. In the study we performed, we observed a significant, strong and negative correlation between the concentration of EPO, hemoglobin, and red blood cell count. A negative trend was also noted on the impact of iron concentration and transferrin saturation on EPO production. In conclusion, this preliminary study demonstrates an impaired impact of endogenous EPO on erythropoiesis in the presence of increased iron content in carriers of p.(His63Asp) (heterozygotes) variant of the HFE gene in developmental age.

G-Quadruplex Structures Colocalize with Transcription Factories and Nuclear Speckles Surrounded by Acetylated and Dimethylated Histones H3.

G-quadruplexes (G4s) are four-stranded helical structures that regulate several nuclear processes, including gene expression and telomere maintenance. We observed that G4s are located in GC-rich (euchromatin) regions and outside the fibrillarin-positive compartment of nucleoli. Genomic regions around G4s were preferentially H3K9 acetylated and H3K9 dimethylated, but H3K9me3 rarely decorated G4 structures. We additionally observed the variability in the number of G4s in selected human and mouse cell lines. We found the highest number of G4s in human embryonic stem cells. We observed the highest degree of colocalization between G4s and transcription factories, positive on the phosphorylated form of RNA polymerase II (RNAP II). Similarly, a high colocalization rate was between G4s and nuclear speckles, enriched in pre-mRNA splicing factor SC-35. PML bodies, the replication protein SMD1, and Cajal bodies colocalized with G4s to a lesser extent. Thus, G4 structures seem to appear mainly in nuclear compartments transcribed via RNAP II, and pre-mRNA is spliced via the SC-35 protein. However, α-amanitin, an inhibitor of RNAP II, did not affect colocalization between G4s and transcription factories as well as G4s and SC-35-positive domains. In addition, irradiation by γ-rays did not change a mutual link between G4s and DNA repair proteins (G4s/γH2AX, G4s/53BP1, and G4s/MDC1), accumulated into DNA damage foci. Described characteristics of G4s seem to be the manifestation of pronounced G4s stability that is likely maintained not only via a high-order organization of these structures but also by a specific histone signature, including H3K9me2, responsible for chromatin compaction.

The relationship between play and language milestones in infancy

ABSTRACT For the current study, a multi-measure, micro-analytic approach was used to prospectively explore the role of preliminary symbolic play with single and multi-objects in language milestone development and vice versa. Fourteen infants followed up in monthly one hour sessions between the ages of 8 and 16 months. Their spontaneous play acts and vocal behaviors were recorded, enabling the coding of vocalization, babbling, and speech. A multivariate model was used to examine the mutual link between the play and language milestones. The results indicated a general reciprocal support tendency between the lingual and play behaviors; however, the simplest forms, vocalization and single-object play, were found to have key roles in cognitive development. Vocalization and babbling were found to correlate with both play forms, and play with a single object was related to the production of all vocal behaviors. The discussion explains the mechanisms of vocalization and single-toy play that enable cognitive growth.

Achene Characteristics of Some Taxa of Asteraceae from the Northwestern Mediterranean Coast of Egypt

THIS STUDY aimed to characterize the external morphology of achenes of the 74 taxa belonging to 51 genera and four subfamilies of Asteraceae from the Northwestern Mediterranean coast of Egypt. By using light microscopy, 26 quantitative and qualitative morphological characters were recorded. Among the studied taxa, achene symmetry, hairiness, surface topography, hilum position, presence or absence of pappus and pappus type were found significant diagnostic characters for delimiting the taxa. Two main groups were identified based on the presence or absence of hardened fruiting involucre. Four types and four subtypes were recognized: (1) Achene di- or trimorphic per capitulum, (2) Achene monomorphic and lacking pappus, (3) Achene monomorphic, with coroniform or auriculate pappus, (4) Achene monomorphic, with pappus. A description, photographs and identification keys were provided to assist in identification. Despite the taxonomic significance of achene exomorphology characters on the generic and specific level for the recognition of the different studied taxa of Asteraceae, no mutual link was shown between the taxonomic division of the family into subfamilies and tribes except for few cases.