The All-Russian scientific and practical conference with international participation “Gribanov Readings — 2022” was held on December 14—16, 2022 at the National Library of the Republic of Sakha (Yakutia). The article discusses the problems of the book culture of the regions of Russia; this theme was in the focus of attention of conference participants and was the subject of scientific discussion at the plenary session and in the course of the sections: “National and local history bibliography: history, status and new horizons”, “Reading infrastructure: research, exchange of experience”, “Historical and cultural studies to preserve the cultural heritage of the indigenous peoples of the Russian North, Siberia and the Far East” and “Digital transformation of libraries”. Within the framework of the conference, there were organized the round table “Modern Library Education: exchange of opinions of practitioners and theorists, managers and performers, teachers and students, readers and librarians” and the First Regional Festival of Scientific Research Cinema “Science Cinema”. The conference aroused great interest in the professional and scientific community. More than 130 specialists took part in it — theorists and practitioners of library and information activities, experts in the book industry, philosophers, historians, ethnographers, cultural scientists, art historians, employees of archives and museums from 30 regions of Russia, as well as from Belarus, Kazakhstan and Mongolia. The conference was aimed at identifying the main vectors of the history and current trends in the development of book culture in the regions of Russia, assessing the role of books and reading, bibliography, modern book publishing, discussing the key issues of the domestic book market, finding ways to digitally transform libraries and preserve the best traditions of the development of the book industry.