This study explores novel techniques to improve the detection accuracy of skarn iron deposits using advanced image-processing methodologies. Leveraging the capabilities of ASTER image, band ratio (BR) images, and principal component analysis (PCA) alongside the power of 3D convolutional neural networks (3D-CNNs), the research aims to enhance the precision and efficiency of ore detection in complex geological environments. The proposed method employs a specific 3D-CNN architecture accepting input as a 7 × 7 × C image patch, where C represents the combined number of selected ASTER image bands, principal component (PC) bands, and computed BR images. To evaluate the accuracy of the proposed method, five distinct image band combinations, including the proposed band combination, were tested and evaluated based on the overall accuracy (OA), average accuracy (AA), and kappa coefficient. The results demonstrated that while the incorporation of BR images alongside ASTER bands initially seemed promising, it introduced significant confusion in certain classifications, leading to unexpected misclassification rates. Surprisingly, utilizing solely ASTER bands as input parameters yielded higher accuracy rates (OA = 93.13%, AA = 91.96%, kappa = 90.91%) compared with scenarios involving the integration with band ratios (OA = 87.02%, AA = 79.15, kappa = 82.60%) or the integration of BR images to PC bands (OA = 87.78%, AA = 82.39%, kappa = 83.81%). However, the amalgamation of ASTER bands with selected PC bands showed slight improvements in accuracy (OA = 94.65%, AA = 92.93%, kappa = 93.45%), although challenges in accurately classifying certain features persisted. Ultimately, the proposed combination of ASTER bands, PC bands, and BR images (proposed band combination) presented the most visually appealing and statistically accurate results (OA = 96.95%, AA = 94.87%, kappa = 95.93%), effectively addressing misclassifications observed in the other combinations. These findings underscore the synergistic contributions of each of the ASTER bands, PC bands, and BR images, with the ASTER bands proving pivotal for optimal skarn classification, the PC bands enhancing intrusions classification accuracy, and the BR images strengthening wall rock classification accuracy. In conclusion, the proposed combination of input image bands emerges as a robust and comprehensive methodology, demonstrating unparalleled accuracy in the remote sensing detection of skarn iron minerals.