Introduction: The Multiprofessional Pain Outpatient Clinic (AMD) was created at the University Hospital of the Federal University of Juiz de Fora (HU-UFJF) to offer an integrated and interprofessional approach to the treatment of chronic pain, in line with the Multiprofessional Residency in Adult Health. To face the complex demands of AMD and promote more engaged and meaningful learning, the need arose to use Active Methodologies (AM) in the teaching-learning process of residents. Objective: To report the creation of a preceptorship plan for the implementation of active methodologies in the teaching-learning process of AMD, with the objective of developing critical, communication and teamwork skills in health professionals and promoting more effective and integrated care for patients with chronic pain. Experience Report: The study adopted the format of an experience report and took place at AMD, involving an interprofessional team composed of residents and preceptors. Several active methodologies were used, such as case studies, problem-based learning, interprofessional teaching, experiential learning, among others. The implementation of active methodologies in AMD demonstrated significant potentialities, including improvements in resident performance, development of communication and teamwork skills, favoring interdisciplinary practices, and academia-service integration. A more active and engaged participation of students in the discussions of clinical cases was observed, resulting in a deeper understanding of the clinical concepts presented. Conclusion: Active methodologies represent an effective strategy to promote learning and professional development in AMD, contributing to a more integrated and efficient care for patients with chronic pain. The study highlights the importance of continuous training of health professionals and the search for innovative practices in the context of chronic pain.