Identifying the severity of trauma to provide timely and adequate treatment and predict the prognosis are some of the significant challenges in trauma management. Increased red blood cell distribution width (RDW) is associated with several pathologies and associated mortality. This study aims to evaluate the RDW in predicting 24h and 30-day mortality among multiple trauma patients. In this retrospective study, multiple trauma patients with ISS ≤16 were included. Blood samples of the patients were collected at 1h and 24h of the referral to determine RDW. Demographic data, 24h and 30-day mortality, injury severity score (ISS), and RDW outcomes were evaluated for all the patients. Of the 300 patients included in the study, 52 patients died in the first 24h, and 85 patients within 30 days. One hour and 24h RDW were not significantly different in 30-day mortality patients, P=0.104 and P=0.156, respectively. RDW in 30-day mortality patients was not significantly different at 1h and 24h, P-value=0.875. The means ISS in 24h, 30-day mortality and survivors was significantly different, P<0.001. Our study does not report a significant increase in RDW among 24h and 30-day mortality and survivor patients. ISS was significantly different among the two groups.