The lateral stability is the crucial feature in a distributed drive electronic vehicle (DDEV). A high speed DDEV in a sharp turn may lose the lateral stability when it encounters fast varied road adhesion coefficients. To solve this problem, a BP-PID controller-based multi-model control system (MMCS) is designed for DDEV via direct yaw-moment control (DYC) in this paper. Firstly, according to the varied road adhesion coefficients, the working circumstance of DDEV is summarized as seven kinds of typical types. A sub-model set is established to accurately describe the operating mode of the working circumstance. Secondly, based on the sub-model set, a nonlinear sub-controller set is constructed with seven off-line tuning BP-PID controllers and an on-line tuning one. The off-line tuning controller can fast calculate the required direct yaw-moment, and the on-line tuning controller is aimed to achieve a high control accuracy. Thirdly, a controller switching policy is composed of an error judgement policy and a model matching policy. Such switching policy is utilized to precisely identify the working circumstance of DDEV and implement switching control. Finally, simulation experiments prove that the designed MMCS shows a significant control performance and guarantees the lateral stability of DDEV under varied road adhesion coefficients.