This article aims to investigate the security consensus and composite anti-disturbance problems for a class of nonlinear multi-agent systems subjected to stochastic false data injection attacks (FDIAs) and multiple disturbances under a directed communication topology. To attenuate and reject of the negative effects of two types of disturbances, a disturbance observer (DO) is designed to counteract the disturbance produced by exogenous system, and the <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mathcal {H}_\infty $ </tex-math></inline-formula> control method is adopted to attenuate the bounded errors and variables caused by the other type of disturbances and FDIAs simultaneously. To ensure the consensus performance of MASs, an observer-based control strategy is designed, and a novel adaptive compensation technique is proposed to not only evaluate the upper bounds of the unknown but bounded disturbances but also improve the accuracy of the state observer. Furthermore, a novel event-triggered mechanism (ETM) without requiring continuous communication among neighboring agents is developed to reduce the controller update frequency and the communication burden. Meanwhile, Zeno behavior is excluded. Finally, numerical simulations are provided to verify the availability of the designed method. Note to Practitioners—In multi-agent systems, network security is very important. For example, in smart power grid systems, it is necessary to use the method of state estimation to observe the system to guarantee its safe operation. However, the measured value of the instrument may be affected by FDIAs in the transmission process, thus changing the result of state estimation and causing misjudgment of the system. Similarly, in multi-vehicle systems, FDIAs may destroy the location information of vehicles and cause serious accidents. In addition, the system will be subjected to different types of disturbances in practice, thus reducing the performance of the system. In view of the threat of FDIAs and disturbances to the MAS, a composite anti-disturbance method and an observer-based control strategy are proposed. Meanwhile, to avoid the limitation of communication bandwidth in reality, a novel ETM is developed to save network resources.