Multicenter Cross-sectional Study Research Articles

Associations between body mass index and physical fitness indicators among Chinese university students: a multicenter cross-sectional study

BackgroundIncreasing body mass index (BMI) has many negative effects on the physical and mental health of university students and has become a common public health problem in all countries. However, there are few studies on the association between BMI and physical fitness indicators among Chinese university students in developing countries, and the findings are inconsistent. The present study aims to analyze the association between BMI and physical fitness indicators among Chinese university students, to assist in university students’ health development and intervention.MethodsIn this study, we conducted a cross-sectional assessment of BMI of 29,371 university students and a cross-sectional assessment of physical fitness indicators of vital capacity, sit and reach, pull-up(boys), sit-up(girls), standing long jump, 50 m dash, 1000 m run(boys ), 800 m run(girls). One-way analysis of variance (ANOVA), Pearson’s correlation analysis, and nonlinear regression modeling were used to analyze the associations that existed between BMI and various physical fitness indicators.ResultsThe percentages of Chinese university students in emaciated, normal, overweight, and obese were 17.8%, 65.3%, 14.9%, and 2.0%, respectively. Comparing between different BMI groups (emaciated, normal, overweight, and obesity), for boys, the effect values ranged from 1.0 to 2.0% for the items of vital capacity, sit and reach, pull-up/situp, standing long jump, 50 m dash, and 1000/800 m-run. For run events, the range of effect sizes ranged from 0.2 to 0.9; the range of effect sizes for girls also ranged from 0.2 to 0.9.ConclusionsThe physical fitness level of emaciated and obese Chinese university students is generally lower than that of normal-weight students, and the relationship between BMI and physical fitness indicators shows a “U-shape” or “inverted U-shape” curve. The effect of BMI on physical fitness is more significant in boys than in university girls. In the future, targeted physical exercise and health education should be provided to emaciated and obese university students to maintain a reasonable body weight and promote the healthy development of physical fitness.

The critical role of education in shaping nurses' attitudes and intentions towards neonatal palliative care: A network analysis

BackgroundNeonatal palliative care is an essential component of comprehensive neonatal care; however, its implementation remains challenging worldwide, particularly in low- and middle-income countries due to limited resources, cultural barriers, and lack of training. ObjectivesThe aim of this study was to investigate the structural characteristics of neonatal nurses' attitudes towards neonatal palliative care and their intention to provide such care using network analysis to identify key influencing factors and interrelationships. DesignA multi-center cross-sectional study. SettingThe setting was 92 hospitals across 28 provinces in mainland China. ParticipantsA convenience sampling method was employed to recruit 893 neonatal nurses from October 2023 to February 2024. MethodsThe web-based survey included a sociodemographic questionnaire, the simplified Chinese version of the Neonatal Palliative Care Attitude Scale (NiPCAS), and a single question gauging participants' intention to provide neonatal palliative care. Network analysis techniques were used to examine the structural characteristics of the attitude network. ResultsA total of 767 valid questionnaires were received. The estimated network comprised 26 nodes representing individual NiPCAS items, with 150 non-zero edges out of a possible 325 connections. In-service education experience emerged as the most central and influential node, demonstrating the highest centrality (strength = 2.511; bridge strength = 3.144) and predictability (R2 = 0.475). This was followed by the ideal palliative care environment and staff support for palliative care. On average, 29.3 % of each item's variance could be accounted for by surrounding items. The strongest associations with the intention to provide neonatal palliative care were observed with beliefs about the necessity of palliative care in neonatal nurse education (edge weight = 0.29). ConclusionsThe findings highlight the pivotal role of in-service education experience in shaping nurses' attitudes towards neonatal palliative care, suggesting that educational interventions may significantly influence overall attitudinal structures. The strong associations between the intention to provide neonatal palliative care, and beliefs about the necessity of palliative care in neonatal nurse education, further reinforce the critical role of education in fostering positive attitudes and intentions. The significance of organizational and resource-related factors suggests that efforts to improve neonatal palliative care should focus on enhancing staff support and creating supportive work environments.

Endometrioma patients are under-treated with endocrine endometriosis therapy.

Is there a difference in the use of endocrine endometriosis therapy in endometriosis patients with and without endometrioma? Patients with endometriomas received significantly less endocrine endometriosis treatment (present intake in 42.5%) compared to patients with other forms of endometriosis and without endometriomas (present intake in 52.1%). Endocrine endometriosis therapy in patients with endometriomas reduces the risk of recurrence and therefore the risk of further surgery and subsequent irreversible damage to ovaries which results into reduced antral follicle counts (AFC), anti-Mullerian hormone levels (AMH), and early menopause. However, there is evidence of increasing rejection of endocrine endometriosis treatment in this population. A total of 838 premenopausal woman with dysmenorrhea and/or endometriosis (mean age 30.7 ± 6.9 years, range 15-54 years) were included in this observational cross-sectional multicenter study. Data including the extent of dysmenorrhea, prevalence of other comorbidities like migraine with aura and migraine never with aura, diagnosis of endometriosis, history of endometriosis surgery, and hormone therapy, were collected in a retrospective online survey from May to November 2023. Patients visiting two university hospital endometriosis centers between January 2017 and March 2023, and with available email address, were invited for study participation by email in May 2023. Further recruitment of participants was achieved through the website and social medial channels of the German Endometriosis Association. Participation in the online survey was open between May and November 2023. In the subgroup of women (with dysmenorrhea) without surgically confirmed endometriosis (SCE) (n = 277), 95 (34.3%) were currently undergoing endocrine treatment for dysmenorrhea and contraceptional purposes. On the contrary, in the subgroup of patients with SCE (n = 561), 275 (49.0%) were currently undergoing hormonal treatment. Subjects with SCE therefore significantly more commonly took endocrine treatment (F = 16.587, P < 0.001) compared to those without SCE. Endometriomas were present in 254 patients (45.2% of all SCE patients), and these patients were significantly less likely to have used hormonal treatment (i) in the present and (ii) in the past (i. n = 113 42.5%, ii. n = 187, 73.9%) compared to patients with other forms of endometriosis (n = 261) (i. n = 139, 52.1%, ii. n = 220, 84.3%) (i. F = 3.976, P = 0.047, ii. F = 8.297, P = 0.004). Various reasons for rejection of endocrine endometriosis treatment were analyzed, when comparing endometrioma subjects to patients with other types of endometriosis, but no statistical differences were found. This study is limited by its retrospective design and an online questionnaire with patient-reported outcomes. A selection bias due to the voluntary nature of the study and the online recruitment is also possible. The results show that patients often refuse endocrine endometriosis treatments without a rational medical reason. According to the literature, this unnecessarily exposes these patients to a higher risk for endometrioma recurrence and subsequently a higher risk of repeat surgery and permanent damage to ovarian function. This study was funded by the University of Luebeck (budget for university teaching and research). A.C. was supported by DFG (CRC/TR 296 'Local control of TH action', LocoTact, P07) and by funds of University of Luebeck, medical section (LACS01-2024). N.B. was supported by the DFG (BR4328.2-1, GRK1957), the Michael J Fox Foundation, the Collaborative Center for X-linked Dystonia-Parkinsonism and the EU Joint Programme-Neurodegenerative Disease Research (JPND). C.C., H.G., C.G., I.A., A.K., A.R. received no funding for this study. There were no competing interests. N/A.

Microplastics in stools and their influencing factors among young adults from three cities in China: A multicenter cross-sectional study

The mass concentration of microplastics in stools and influencing factors remain unclear. The aim was to investigate the types and mass concentrations of microplastics in the stools of young college students and to explore potential influencing factors. Twenty-six participants were recruited from colleges in each city using stratified simple sampling, including Changsha, Shanghai, and Changchun. Participants’ dietary and fluid intake behavior was recorded using the 3-day 24-h dietary questionnaire and the 7-day 24-h fluid intake record, respectively. Lifestyle factor information related to microplastic exposure was collected through a microplastic exposure questionnaire. Stools were collected and detected using pyrolysis gas chromatography–mass spectrometry (Py-GCMS) method. Eventually, 78 participants completed the study. The detection rate of microplastics, including polyethylene (PE), polyvinyl chloride (PVC), polystyrene (PS), polypropylene (PP) and polyethylene terephthalate (PET), in stools was 98.7%, with a total mass concentration of 54.7 (10.1–102.7) μg/g. There were differences in the total mass concentrations of microplastics in the stools of participants in three cities, namely Changsha, Shanghai, and Changchun, which decreased sequentially (χ2 = 47.819, P < 0.05). Participants with a relatively high frequency of takeaway food consumption had higher total mass concentrations of microplastics mass concentrations in stools (χ2 = 7.390, P < 0.05). Participants with a relatively high frequency of consuming reheated food had a greater mass concentration of PET microplastics (χ2 = 6.117, P < 0.05). The total mass concentration of microplastics, as well as the mass concentrations of PE, PVC, PP, and PA66, in the bottled water intake group were greater than those in the nonintake group (all P < 0.05). Overall, the total mass concentration of microplastics in stools was related to residential city, consumption of reheated food, and bottled water intake (all P < 0.05). Young college students generally experience microplastic exposure, with the main types being PE, PVC, PS, PP, PET, and PA66. Living location, reheated food consumption, and bottled water intake were factors influencing microplastic exposure.

The Prevalences of Behavioral Problems in Children and adolescents in Chengdu, Sichuan, China and Associated Risk Factors: A Multi-Center Cross-Sectional Study

ABSTRACT This study aimed to investigate the prevalence of behavioral problems in children and adolescents in Chengdu, Sichuan, China and the associated risk factors. A questionnaire survey was conducted with the students and their parents or caregivers from five primary and middle schools to investigate the parent–child relationship, family financial situations, health risk behaviors, and behavioral problems. A total of 8157 questionnaires were distributed, and 7928 (97.19%) valid questionnaires were returned. Among the 7928 valid questionnaires, 3846 were completed by female students and their parents or caregivers, and 4082 were completed by male students and their parents or caregivers. The average age of the surveyed students was 10.62 years. The prevalence rate of behavioral problems in children and adolescents was 13.79%, and the prevalence rate of behavioral problems significantly varied by gender and age. The female students had a higher prevalence rate of behavioral problems than male students (14.6% versus 13.0%). The students aged 12–16 years had a higher prevalence rate of behavioral problems than those aged 6–11 years (16.4% versus 12.2%). A correlation between behavioral problems and weekly pocket money was detected in the children and adolescents. Poor parent–child relationships, excessive screen time for both parents and children, short duration of sleep, and excessive intake of sugar-sweetened beverages could lead to a significant increase to the risk of developing behavioral problems in children and adolescents. Health-risky behaviors in children and adolescents were closely correlated to their behavioral problems. More attention should be paid to encouraging children and adolescents to live healthy lifestyles and tackling their behavioral problems.

Development and Validation of a Sexual Quality of Life Score for Youths with Inflammatory Bowel Disease.

Inflammatory Bowel Disease (IBD) are known to impact patients 'sexual lives. The aim of this study is to create and validate a sexual QoL designed for youth with IBD. This study was conducted in two phases: development of the score and validation of the items. A multidisciplinary team created a score called BLOOMI, based on two validated scores: the International Index of Erectile Function (IIEF) and the Sexual Function Questionnaire 28 (SFQ28). It was validated through a French multicentric cross-sectional study among patients aged 15-25 years with IBD by comparison with IIEF and SFQ28 gold standard scores. BLOOMI is a sexual QoL designed with 10 items and formatted as a disk. The score was validated through the participation of 104 patients with a median age of 23.2 years. BLOOMI was well correlated with both goldstandards and had a strong internal consistency. 19.1% of IIEF-responders have erectile dysfunction and median scores for the SFQ domains Desire, Arousal sensation and cognition, and orgasm are below the threshold for the absence of sexual dysfunction. Fatigue, abdominal pain, body image concerns or fear of anal leakages are correlated to a poorer sexual QoL. BLOOMI score is a new validated score to assess the sexual QoL in 15-25 years with IBD. This tool may improve the screening for sexual challenges encountered by youths with IBD and may support future research into the impact of IBD on young patients' lives.

Perception, practice and associated factors of labour pain management among obstetric care providers in public health facilities in Harari Region, Ethiopia: a multicentre cross-sectional study.

Although providing relief from labour pain can improve the mother's satisfaction with the birthing process and lead to better reproductive outcomes. This study aims to evaluate the perceptions, practices and related aspects of labour pain management among obstetric care providers in public health institutions in the Harari Region of Ethiopia. A cross-sectional study was conducted in the labour and delivery wards of public health facilities in the Harari Region. Data were collected using a semi-structured and pretested self-administered questionnaire among systematically selected obstetrics care providers (OCPs). A multivariate logistic regression model was used to identify factors associated with the practice of labour pain management. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to determine the strength of associations and a p-value <0.05 was considered significantly associated. Data from 234 OCPs were employed for analysis. A total of 70.9% of OCPs have positive perceptions and 69.7% practiced labour pain management in the past 4weeks. Being a female (adjusted OR [aOR] 2.33 [95% CI 1.06 to 5.15]), having a positive perception (aOR 7.76 [95% CI 3.21 to 18.72]), being a physician (aOR 6.35 [95% CI 1.94 to 20.82]), being a midwife (aOR 5.28 [95% CI 1.78 to 15.63]) and being a highly qualified OCP (aOR 17.89 [95% CI 5.22 to 61.30]) were associated with being more likely to practice labour pain management. Positive attitude (aOR 2.77 [95% CI 1.51 to 8.72]), being a physician (aOR 6.01 [95% CI 1.23 to 29.35]) and practicing labour pain management (aOR 12.89 [95% CI 4.57 to 36.38]) were associated with labour pain management perceptions. Seven of ten OCPs practiced labour pain relief methods and had a positive perception of managing labour pain. Therefore, facilitating training and improving the perceptions and attitudes of OCPs towards labour pain management should be encouraged.

Malnutrition and associated risk factors in orphanages in Punjab, Pakistan: an analytical study

BackgroundChildren living in orphanages face an increased susceptibility to malnutrition due to inadequate nutrition and psychological factors, in comparison to children who stay with their parents. A considerable proportion of...

Lesson in understanding parents’ perspective: perception of quality of care and COVID-19-related fears among users of paediatric health services over the COVID-19 pandemic in 11 facilities in Italy

BackgroundThe COVID-19 pandemic had an important psychological impact on children and their families. This study aims to explore paediatric health services users’ perceptions of quality of care (QOC) and COVID-19-related...

Barriers to the Acceptance of Tuberculosis Preventive Treatment: A Multicenter Cross-sectional Study in China.

We aimed to understand the willingness and barriers to the acceptance of tuberculosis (TB) preventive treatment (TPT) among people with latent TB infection (LTBI) in China. A multicenter cross-sectional study was conducted from May 18, 2023 to December 31, 2023 across 10 counties in China. According to a national technical guide, we included healthcare workers, students, teachers, and others occupations aged 15-65 years as our research participants. Overall, 17.0% (183/1,077) of participants accepted TPT. There were statistically significant differences in the acceptance rate of TPT among different sexes, ages, educational levels, and occupations ( P < 0.05). The main barriers to TPT acceptance were misconceptions that it had uncertain effects on prevention (57.8%, 517/894), and concerns about side effects (32.7%, 292/894). An enhanced and comprehensive understanding of LTBI and TPT among people with LTBI is vital to further expand TPT in China. Moreover, targeted policies need to be developed to address barriers faced by different groups of people.

The impact of patients’ preference for pharmaceutical dosage forms on medication discontinuation among patients attending Red Cross pharmacies in Northwest Ethiopia

Medication discontinuation poses a significant challenge to the effectiveness of therapeutic interventions and overall patient treatment outcomes. Improving the pharmaceutical dosage forms’ acceptability for patients, knowledge of proper ways for medication usage, and proper storage of medications play an indispensable role in enhancing patient safety. Thus the present study aimed to assess patients’ preferences for pharmaceutical dosage forms, their knowledge of storage of medications, and factors associated with medication discontinuation among patients attending Red Cross pharmacies in Northwest Ethiopia. This multicenter cross-sectional study was conducted from January 16, 2024, to February 15, 2024. The collected data was entered into EpiData (version 4.6.0) and statistical analysis was carried out by exporting to STATA version 14. A p-value of less than 0.05 was statistically considered as significant. Among 388 study participants, more than half (54.4%) had a history of medication discontinuation and frequency of administration was the most contributing factor (39.4%). The common reason for study participants’ dosage form preferences was the ease of use (62.1%), followed by high efficacy and safety (11.9%). Rural residency [AOR = 1.61; 95%CI: 1.03, 2.52], number of medications [AOR = 4.29; 95%CI: 2.03, 9.06], preference for the type of dosage forms [AOR = 5.86; 95% CI: 3.36, 10.21], and frequency of administration [AOR = 2.49; 95%CI: 1.55, 3.99] were factors significantly associated with medication discontinuation. The present study revealed that more than half of the study participants had a history of medication discontinuation.To reduce medication discontinuation and enhance the treatment outcome of patients, medical and pharmacy professionals should improve information concerning dosage forms and their acceptability for patients through ongoing patient education and training.

Burden of incidental cerebral aneurysms on lifestyle and quality of life: a survey of patients in expectant management (the SPICE Study)

BackgroundThe increasing availability of neuroimaging tests has led to a rise in the identification of incidental unruptured intracranial aneurysms (UIAs). Their management is under debate, with no consensus on their...

Factors affecting the level of medication adherence to anti-diabetic treatment: A multi- center cross-sectional study in Eastern Bhutan

Background: Worldwide, Diabetes Mellitus affects millions of people. It is a chronic and progressive disease requiring a long-term treatment plan, adherence to which becomes extremely challenging. Globally, there is a poor level of medication adherence to anti-diabetic treatment and several studies have explored the factors affecting medication adherence. However, in Bhutan, there is limited data on the rate of medication adherence and factors affecting it. . Therefore, the study aimed to find the level of anti- diabetic medication adherence and factors affecting it. Methods: A multicenter cross-sectional observational study was conducted involving six eastern district hospitals from June 2019 to February 2020. Research participants were randomly selected from the daily cohort of patients visiting diabetic clinics. Results: Amongst the 390 participants, the overall level of adherence reported in this study was intermediate with a mean Morisky Medication Adherence Scale 8 Items (MMAS-8) score of 6.06 (95% CI 5.91-6.22). Nearly 40% demonstrated a low level of adherence (MMAS-8 score &lt;6). There was a statistically significant (p&lt;0.05) association between mean MMAS-8 scores and adverse drug reactions, the drug regimen (polypharmacy or monotherapy) and the type of diabetes mellitus. Conclusion: This study revealed an intermediate level of medication adherence to anti-diabetic treatment in the eastern region of Bhutan. Adverse drug reactions and polypharmacy resulted in a lower level of adherence. However, further studies are needed to draw a definitive conclusion.

Risky sexual practice and associated factors among antiretroviral therapy attendees in public health facilities, Wolaita Zone, South Ethiopia: a multi-center cross-sectional study.

The majority of people living with Human Immunodeficiency Virus (HIV) are in low- and middle-income countries, particularly in sub-Saharan Africa. Increased risky sexual practice puts people living with the human immune virus at higher risk of acquiring sexually transmitted infections other than the human immune virus and unplanned pregnancies. Sexually transmitted infections, particularly viral hepatitis (B and C), significantly impair antiretroviral therapy and the clinical outcome of the co-infected individual, leading to increased morbidity and mortality. The purpose of this study was to investigate the prevalence of risky sexual practices among antiretroviral therapy (ART) attendees in public health facilities within the Wolaita Zone of South Ethiopia. From September to October 2023, a facility-based cross-sectional study was conducted among adult people living with HIV on ART in the Wolaita zone. Data was collected through a pretested and structured questionnaire. Six diploma nurses were trained to collect data. Systematic sampling techniques were used to select a total of 398 ART patients. Data were collected by Open Data Kit (ODK) and analyzed with SPSS Version 25. Binary and multiple logistic regression analyses were used. All the variables with a P-value of 0.25 associated with risky sexual practices are considered candidate variables. Multicollinearity was checked. The fitness of the model was tested by the Hosmer-Lemshow goodness of fit test. Finally, statistical significance was declared at a p-value of 0.05. A total of 398 respondents took part in this study. The prevalence of risky sexual practices in the past six months was 174 (43.7%) at 95% of the CI (38.9-48.7). The result of multiple logistic regression analysis showed that not disclosing HIV status (AOR = 1.8, 95% CI: 1.1-3.31), alcohol drinking (AOR = 3.1, 95% CI: 1.66-0.023), and poor social support (AOR = 1.9, 95% CI: 1.75-3.9) were statistically significantly associated with risky sexual practices. This study revealed that the risky sexual practice among ART clients was high and disclosure status, social support, and alcohol use were factors associated with risky sexual practice. The governmental and non-governmental bodies have to strengthen social support for ART clients, disclosure status for ART clients, and counseling to avoid alcohol.

Evaluation of participation in a former rehabilitation population: a comparison between USER-Participation Restriction and Satisfaction subscales and PROMIS Ability to Participate and PROMIS Satisfaction with participation 8-item short forms in a cross-sectional multicentre study

Background Several Patient Reported Outcome Measurements (PROMs) can be used to quantify participation in rehabilitation patients, yet there is limited comparative research on their content and psychometric properties to make an informed decision between them. Objective To compare the content and several psychometric properties of the Restriction and Satisfaction subscales of the Utrecht Scale for Evaluation of Rehabilitation – Participation (USER-P) with the Patient-Reported Outcomes Measurement Information System Ability to Participate in Social Roles and Activities (PROMIS-APS) and Satisfaction with Social Roles and Activities (PROMIS-SPS) v2.0 8-item short forms. Methods A cross-sectional survey among patients who received rehabilitation treatment (N = 563). Coverage of participation domains, distributions, inter-item correlations, internal consistency, construct validity, and discriminative validity were compared between the PROMs. Results The USER-P subscales cover more participation domains than the PROMIS short forms. All PROMs demonstrated adequate internal consistency (α > 0.82) and each had >75% of the hypotheses regarding construct validity confirmed. Conclusions The internal consistency, construct and discriminative validity were similar between the USER-P subscales and the PROMIS short forms. It appeared that the USER-P offers more broad information about participation on item level and the total scores of PROMIS short forms offer more precise general information regarding participation.

The 3-level Wells score combined with D-dimer can accurately diagnose acute pulmonary embolism in hospitalized patients with acute exacerbation of COPD: A multicentre cohort study

BackgroundIdentification of acute pulmonary embolism (APE) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is challenging. Wells score and Revised Geneva score have been developed to diagnose APE. We aim to investigate the predictive accuracy of two clinical scoring systems combined with D-dimer for APE in patients with AECOPD. MethodsA multicentre cross-sectional study was conducted in 13 China hospitals. A total of 731 patients were enrolled. Computed tomography pulmonary angiography (CTPA) was performed within 48 hours of admission. The performance of the clinical scoring systems was compared by calculating the area under the receiver operating characteristic curves (AUROC), sensitivities, and specificities. Results731 patients were included with an average age of 68.9 years, with a male proportion of 585 (80.0 %). 112 (15.3 %) were diagnosed with APE. The optimal D-dimer cut-off value for identifying APE in AECOPD was 690.12 ng/mL. Analysis for assessing the clinical probability of APE using the 3-level Wells and Revised Geneva scores showed the AUC were 0.74 and 0.60, sensitivity were 61.61 % and 77.68 %, and specificity were 85.46 % and 38.29 %, respectively. Analysis using the 3-level Wells and Revised Geneva scores combined with a D-dimer cut-off value of 690.12 ng/mL showed the AUC were 0.909 and 0.869, sensitivity were 73.21 % and 91.96 %, specificity were 92.08 %and 72.70 %. The performance of the 3-level Wells score with D-dimer was significantly better than the performance of the 3-level Revised Geneva score with D-dimer (P = 0.01). ConclusionsThe 3-level Wells score combined with a D-dimer cut-off value of 690.12 ng/mL performed better than other clinical scoring algorithms for assessing clinical probability of APE in patients with AECOPD.

Relationship between the sense of nursing professional pride and adversity quotient, grit levels among nurses in blood purification centers: a multicenter cross-sectional study.

This study aims to examine nursing professional pride levels in blood purification center nurses, explore its relationship with adversity quotient and grit, and identify influencing factors. Using convenience sampling, this study selected 231 nurses from blood purification centers at 11 tertiary hospitals in China during July to August 2023 as research subjects. A general data survey questionnaire, nurse professional pride scale, nurse adversity quotient self-assessment scale, and the Oviedo resilience scale were employed for the investigation. The results were statistically analyzed using descriptive analysis, t-tests, one-way ANOVA, Pearson correlation analysis, and multiple stepwise linear regression analysis. In the blood purification center, the average scores were as follows: nursing professional pride (69.53 ± 15.21), adversity quotient (132.90 ± 41.10), and grit (30.95 ± 10.54). There was a significant positive correlation between nursing professional pride, adversity quotient, and grit (P < 0.001). Multiple linear regression analysis (n = 231) revealed that education background, professional title, average monthly income, adversity quotient, and grit significantly influenced nursing professional pride (P < 0.001). The R 2 value indicates that this study accounted for 76.2% of the total variance in nursing professional pride. The findings of this study indicate that blood purification center nurses have a moderate level of nursing professional pride. The level of nursing professional pride can be enhanced by focusing on factors such as adversity quotient and grit. This study was approved by the Ethics Committee of Pidu District People's Hospital, Chengdu, China (2021 No. 231). All participants were informed of the relevant information and research purposes before their participation. Participants were also required to independently and anonymously complete the questionnaires.

Association of plant and animal protein intake with sleep quality and quality of life in hemodialysis patients: a multicenter cross-sectional study.

The current study aimed to evaluate the association between the intake of plant-based protein, animal-based protein, total protein, and the ratio of plant to animal protein with sleep quality and quality of life in patients undergoing hemodialysis. In this cross-sectional study, 479 adult patients undergoing dialysis for a minimum of 3 months were included. The dietary intake was calculated using information from a validated 168-item semi-quantitative food frequency questionnaire. Quality of life (QOL) was assessed using the Kidney Disease Quality of Life Short Form (KDQOL-SF 1.3). and the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. In this study, the mean age of the participants was 58.18 years (± 14.25 years), with the majority being male (58.2%). After adjusting for potential confounders, significant positive associations were observed between total protein intake (β = 0.12, p = 0.03) and quality of life (QOL). Conversely, there were significant negative associations between the ratio of plant to animal protein intake (β = -0.94, p < 0.01) and QOL. Furthermore, significant negative associations were found between total protein intake (β = -0.02, p < 0.05) and animal protein intake (β = -0.19, p < 0.05) with poor sleep quality. Additionally, there were significant positive associations between the ratio of plant to animal protein intake (β = 0.188, p < 0.05) and poor sleep quality. Increased consumption of animal protein is associated with improved sleep quality and Quality of Life (QOL) in patients undergoing hemodialysis (HD). Further research, especially prospective studies, is required to confirm these associations.

Current status and influencing factors of kinesiophobia in patients with peritoneal dialysis: a multicenter cross-sectional study

BackgroundKinesiophobia, an irrational fear-avoidance behaviour, can significantly impact the quality of life and prognosis of peritoneal dialysis patients. This study aimed to assess the prevalence of kinesiophobia in patients undergoing peritoneal dialysis and to analyse its influencing factors.MethodsA total of 291 patients who visited the outpatient and ward of peritoneal dialysis in 7 tertiary hospitals in Jiangsu Province from December 2023 to March 2024 were selected as research subjects via the convenience sampling method. A cross-sectional survey was conducted using a general data questionnaire, the Tampa Kinesiophobia-11 Scale, the Chinese Version of the Multidimensional Fatigue Symptom Scale, and the Simplified Coping Style Questionnaire.ResultsThe score obtained using the Tampa Scale for kinesiophobia in patients with peritoneal dialysis was 22.44 ± 7.46, with a prevalence rate of 69.1%. Binary logistic regression analysis revealed that no complications, daily exercise before illness, and positive coping styles were protective factors (p < 0.05), whereas fatigue and negative coping styles were risk factors for kinesiophobia in patients receiving peritoneal dialysis (p < 0.05).ConclusionsThe prevalence of kinesiophobia in patients receiving peritoneal dialysis was high but at a mild level. Medical staff should combine influencing factors to identify high-risk groups as early as possible, formulate targeted interventions to reduce the occurrence of kinesiophobia and mitigate adverse effects on peritoneal dialysis patients.

Multicentric study of adherence to antiseizure medications among adults with epilepsy attended in neurology departments in Burkina Faso.

To study the adherence of antiseizures medication in neurology in the city of Ouagadougou. We conducted a multicentric cross-sectional study on adherence to antiseizure medications among adult patients with epilepsy followed by outpatient neurology consultations. The patients were recruited from November 22, 2021 to February 22, 2022 in four departments of neurology. Adherence to antiseizure medications (ASM) was measured using the Morisky Medication Adhesion Scale (MMAS). Logistic regression analysis was used to investigate factors associated with adherence. One hundred and seven patients with a mean age of 38.92 ± 16.06 years were included in the study. Most of the patients were men (52.34%). Twenty-eight patients complied well with ASM (26.17%). The main causes of nonadherence to treatment were forgetfulness and lack of financial means. Factors associated with nonadherence were rural residence (p = 0.023), celibacy or divorce (p = 0.002), low level of education (p = 0.028), perception of stigma (p = 0.026), duration of epilepsy <5 years (p = 0.009). Adherence to ASM is low in Burkina Faso. The main causes of nonadherence were forgetting and insufficiency of financial resources. Rural residence, celibacy, or divorce, low level of education, perception of stigmatization, and short duration of epilepsy were associated with non-adherence. Studies on adherence to antiseizure medications are rare in Africa while patients do not have access to adequate treatment. The aim of our study was to evaluate the adherence to antiseizure medications among patients with epilepsy followed by the neurology departments in the city of Ouagadougou. Forgetfulness and financial insufficiency were the main causes of treatment interruption. Our study showed that most of the patients were non adherent. Several factors such as place of residence, level of education, and duration of epilepsy influence the level of compliance.