This paper introduces a novel high-gain circularly polarized (CP) antenna that utilizes a NRZI (Near Zero Refractive Index) and MNG (Mu Negative) metamaterialslab. The antenna employs a substrate integrated waveguide (SIW) technique and loaded with compact square split ring resonator (SSRR) combined with a hexagonal-shaped structure by a 0.2 mm width slab as a unit cell to achieve high gain and circular polarization. The metamaterial characteristics were examined through material wave propagation in two main directions at the y and x-axis. For wave propagation at the y-axis, the MTM structure demonstrates mu-near-zero (MNZ) with more than 88 GHz bandwidth, NZRI, and Epsilon-Near-Zero (ENZ) properties. However, for x-axis wave propagation, it indicates a wide negative range of single mu metamaterial from 176 to 220 GHz, NZRI, and ENZ properties. By using six unit cells, the antenna acts as an aperture-efficient focusing metasurface lens and polarization converter for a primary source antenna. The NRZI-MNG enhances the gain of the suggested antenna by 6–7 dB, and converts the linearly polarized wave emitted by the patch antenna into circularly polarized waves. The designed antenna has an impedance bandwidth from 176.5 to 285 GHz, with a 3 dB axial ratio achieved from 177 to 204 GHz. The peak gain of the antenna is 11.3 dBi at 223 GHz, and a gain of around 10 dBi is achieved over the entire CP bandwidth with a good cross-polarization level. In addition, the transmittance of the suggested metamaterial antenna is between 80% and 90% in the operating band. These excellent performances make this antenna very promising for sub-THz 6G applications.