Since ancient times, infectious diseases have been a major source of harm to human health. Therefore, scientists have established many mathematical models in the history of fighting infectious diseases to study the law of infection and then analyzed the practicability and effectiveness of various prevention and control measures, providing a scientific basis for human prevention and research of infectious diseases. However, due to the great differences in the transmission mechanisms and modes of many diseases, there are many kinds of infectious disease dynamic models, which make the research more and more difficult. With the continuous progress of infectious disease research technology, people have adopted more ways to prevent and interfere with the derivation and spread of infectious disease, which will make the state of infectious disease system change in an instant. The mutation of this state can be described more scientifically and reasonably by the mathematical impulse dynamic system, which makes the research more practical. Based on this, a time-delay differential system model of infectious disease under impulse effect was established by means of impulse differential equation theory. A class of periodic boundary value problems for impulsive integrodifferential equations of mixed type with integral boundary conditions was studied. The existence of periodic solutions of these equations was obtained by using the comparison theorem, upper and lower solution methods, and the monotone iteration technique. Finally, combined with the practical application, the established time-delay differential system model was applied to the prediction of the stability and persistence of the infectious disease dynamic system, and the correctness of the conclusion was further verified. This study provides some reference for the prevention and treatment of infectious diseases.
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