When scholars investigate criminal behaviour, they observe the existence of several criminal organizations characterized by a continuous involvement in illegal activities over successive generations. There is a potential hereditary transmission of criminal conduct. The topic of heredity invariably encompasses the issue of chromosomes and genes, as these elements are essential to the process of heredity. Currently, there is a lack of empirical evidence supporting the notion of criminal genes, and the consensus among scholars in the field of criminal psychology is that criminal behaviour is a multifaceted outcome influenced by physiological, social, and psychological factors. In contemporary times, within the framework of the expeditious advancement of science and technology, there has been a corresponding escalation in the incidence of criminal activities. Researchers have extensively investigated potential connections or shared characteristics among individuals involved in criminal activities across numerous situations. Scientists have directed their attention on genes, seeing them as the fundamental basis of emerging biotechnologies. This research employs a literature review and analysis method to provide a succinct description of the association between the MAOA (Monoamine oxidase A) and CDH-13 (Cadherin-13) genes and criminal behaviour. Furthermore, it examines specific instances to investigate the potential role of genetic factors in contributing to criminal tendencies.