Abstract. In the article it is provided a comparative analysis of monetary regulation models and explores their impact on economic growth. The aim of the paper is to study models of monetary regulation and their impact on economic growth. It has been established that monetary regulation of any country in the world should be aimed at ensuring economic growth. The authors of the article proved that monetary regulation should be considered as a source of economic shifts, an increase in real wages and living standards accordingly; it acts as a measure of inflationary processes’ containment, which, in turn, meets strategic objectives of monetary policy. The study showed that the rapid development of monetary policy and economic growth theories is marked by certain contradictions, uncertainty and cross flows. The evolution of theories is represented by the Keynesian Liquidity Preference Theory, Monetarism, Neoclassical Real business-cycle theory, the Neo-Keynesian model, and the New Consensus Model. Each of the models has its own characteristics, based on the objects of monetary regulation (money supply, inflation, interest rates, exchange rate). Based on the analysis of the views of researchers on the impact of monetary regulation on economic growth, the authors concluded that concepts are divided according to those that characterize weak relations between these phenomena, and those that prove close correlation. It is concluded that the influence of monetary regulation on economic growth takes place when choosing the regulatory model itself and instruments for its implementation. It is proved that the model of monetary regulation should be based on developed monetary rules. The authors of the article proved that in Ukraine, in conditions of using a monetary design based on the inflation targeting regime and taking into account the importance of increasing the efficiency of using main instruments of monetary regulation, it is necessary, first of all, to ensure the consistency of monetary and fiscal policies. The coordination of monetary and fiscal policies should consist in developing and implementing them in such a way that they do not contradict each other and together contribute to the achievement of the common goals of economic policy, such as sustainable economic growth and low unemployment in terms of long-term price and external stabilities. It is concluded that the insufficient efficiency of the monetary transmission mechanism is reflected in the imbalance of money and foreign exchange markets, the deformation of the credit market and the credit climate degradation, and the decrease in the influence of monetary impulses of the central bank on both the financial system and the real sector of the economy. That is, the main problem of the significant influence of monetary regulation on economic growth in the country lies in restoring the effectiveness of the channels of the transmission mechanism of monetary policy, which depends on the choice of monetary design. Keywords: monetary design, economic growth, monetary instruments, monetary regulation, monetary rules. JEL Classification E50, 58; O49 Formulas: 0; fig.: 7; tabl.: 0; bibl.: 23.