Modification Of Criteria Research Articles

COVID-19: Challenges and viewpoints from low-and-middle-income Asian countries perspectives

The crisis of coronavirus disease (COVID-19) is growing and has a potential impact on low-and-middle-income countries (LMICs), particularly in Asian regions, which, have reported less so far. The main purpose of this article is to discuss the challenges of COVID-19 management in Asian LMICs and propose some future guidelines to control the transmission and spread. Due to a highly dense population, low-resourced health system, lack of testing kit, and tracing, the ultimate impact could be lasting. It is highly likely that Asian LMICs were not in the center of receiving high priority by the international community in order to take effective prevention strategies. This might upsurge caseloads. Like the symptoms, mode of transmission varies largely due to a number of unknown clinical features of the virus, defining a risk group only based on some limited criteria such as age and disease with comorbidity could be risky. Recently some of the Asian LMICs launched contact tracing app. However, the study has identified several healthcare challenges in Asian LMICs such as shortage of supply of PPE, inadequate long-term care services, the socio-cultural differences which require utmost consideration. In addition, to control infection and enhance prevention, some pertinent problems need to be addressed. Based on that, some multifactorial approaches can be taken in line with international guidelines. Finally, this paper recommends developing a strong and resilient healthcare monitoring system.

Automating occupation: International humanitarian and human rights law implications of the deployment of facial recognition technologies in the occupied Palestinian territory

AbstractIn 2019, media investigations revealed that Israel had added facial recognition technologies (FRTs) to the panoply of security and surveillance technologies deployed in its administration and control of the occupied Palestinian territory (oPt). Despite growing academic and judicial scrutiny of the legal implications of these technologies for privacy and freedom of assembly in domestic contexts, scant attention has been paid to their uses by militaries in contexts where international humanitarian law (IHL) applies. This article seeks to establish the international legal framework governing an Occupying Power's deployment of FRTs, particularly in surveillance, and apply it to Israel's uses in the oPt. It is demonstrated that IHL provides flexible, but incomplete, provisions for balancing an Occupying Power's right to employ surveillance technologies within its measures of control and security against the imprecisely defined humanitarian interests of the population under occupation. The relevant legal framework is completed through the concurrent application of an Occupying Power's international human rights law (IHRL) obligations. What is known of Israel's use of FRTs in surveillance appears prima facie not to satisfy the cumulative IHRL criteria for limitations on the right to privacy – legality, legitimate aims, necessity and proportionality – even where these are broadened by reference to IHL. Consideration is also paid to corollary human rights impacts of these technologies, and the potential that they may entrench an Occupying Power's control while simultaneously rendering this control more invisible, remote and less reliant on the physical presence of troops.

August 2020 Highlights.

August 2020 Highlights.

Support Surfaces for Pressure Ulcer Prevention in Intensive Care Patients: A Short Review Article

Objective: This short review seeks to present the effectiveness of support surfaces for pressure ulcer prevention in intensive care patients. Methods: A literature search was undertaken of international databases (PubMed, CINAHL, and Cochrane Library). A time limited criteria was applied with respect to articles publication; articles published in the last decade (2010-2020). As key words, the following terms were used: “pressure ulcers”, “support surfaces”, “intensive care unit”, “prevention”, “mattresses”. Randomized controlled trials (RCTs), which assessed the effectiveness of mattresses for the prevention of pressure ulcers, in intensive care unit (ICU) patients were included in this review. Results: Many researchers have compared support surfaces and revealed the effectiveness between different types of support surfaces. From the present short review of the literature, researchers made an effort to compare the standard hospital mattress with viscoelastic mattress. It was found that the viscoelastic type of mattress reduced the incidence of PUs in critical ill patients. Moreover, some researchers underline the need for systematic and ongoing assessment of the patient’s skin as well as implementation of prevention measures. Conclusions: Viscoelastic mattress seems to be more effective compared to standard foam mattresses in prevention of PUs, in ICU patients. Coping strategies can be developed through an organized intensive care team for PUs prevention.

Assessing Spatial Limits of Sentinel-2 Data on Arable Crops in the Context of Checks by Monitoring

The availability of large amounts of Sentinel-2 data has been a trigger for its increasing exploitation in various types of applications. It is, therefore, of importance to understand the limits above which these data still guarantee a meaningful outcome. This paper proposes a new method to quantify and specify restrictions of the Sentinel-2 imagery in the context of checks by monitoring, a newly introduced control approach within the European Common Agriculture Policy framework. The method consists of a comparison of normalized difference vegetation index (NDVI) time series constructed from data of different spatial resolution to estimate the performance and limits of the coarser one. Using similarity assessment of Sentinel-2 (10 m pixel size) and PlanetScope (3 m pixel size) NDVI time series, it was estimated that for 10% out of 867 fields less than 0.5 ha in size, Sentinel-2 data did not provide reliable evidence of the activity or state of the agriculture field over a given timeframe. Statistical analysis revealed that the number of clean or full pixels and the proportion of pixels lost after an application of a 5-m (1/2 pixel) negative buffer are the geospatial parameters of the field that have the highest influence on the ability of the Sentinel-2 data to qualify the field’s state in time. We specified the following limiting criteria: at least 8 full pixels inside a border and less than 60% of pixels lost. It was concluded that compliance with the criteria still assures a high level of extracted information reliability. Our research proved the promising potential, which was higher than anticipated, of Sentinel-2 data for the continuous state assessment of small fields. The method could be applied to other sensors and indicators.

TAKING INTO ACCOUNT FUNCTIONAL LIMITATIONS IN ASSESSING THE RISK OF INJURY OF EMPLOYEE WITH DISABILITY

The organization of employment of vulnerable groups, including people with disabilities, is an important so-cio-economic issue, because providing opportunities for professional development creates the conditions for im-proving the level of economic protectability of disabled person, as well as has a positive influence on his psycho-logical state. However, the employment of people with special needs at the workplaces is connected with an in-creased risk of injury. This is due to the presence of persistent functional changes in the health state of workers with disabilities, as well as dangerous and harmful factors present at the workplace. Therefore, employers seek to avoid employing people with disabilities, despite the requirements of human rights law, anti-discrimination laws, and programs and services aimed to provide support and employment opportunities for people with disabilities. The purpose of the article is to develop a scientifically grounded approach to taking into account the func-tional state of persons with disabilities in determining the risk of injury at performing production tasks at the workplaces of enterprises of basic sectors of the economy. The novelty of the approach to risk assessment is based on the using individual risk of injury specific to the enterprise of a particular industry, taking into account the functional state of a person with a disability working at a particular workplace, carried out by using the appro-priate coefficient. The value of the coefficient depends on the number of criteria for life activity limitations, which are determined by the medical and social expert commission, as well as the maximum value of the severity of the criteria. Thus, the proposed approach allows taking into account not only the general level of injuries inherent in a particular industry, but also the individual characteristics of a particular employee. This approach allows providing the employer with information in decision-making about improving the management system of occupa-tional safety at the enterprise. Keywords: person with disability, occupational safety, individual risk, trauma

Direct Mass Spectrometry with Online Headspace Sample Pretreatment for Continuous Water Quality Monitoring

This study investigates the use of selected ion flow tube mass spectrometry with an automated headspace pretreatment system for the continuous surveillance of water quality at wastewater treatment plants (WWTPs) and rivers. The reaction rates of the target compounds introduced using the headspace method were similar to those of the mass scan library, with a margin of error of <10%. Novel quantitative formulae were derived for the water samples of the target compounds, and the linearity of the calibration curves for both the purified and effluent matrix (0.1–2.0 mg/L) showed a coefficient of determination of 0.98–0.99 for most compounds. The detection limit for 74% of the target substances was 0.02–0.10 mg/L, and the average recoveries were 111.6% and 104.7% for the low- and high-concentration spiked samples, respectively, which are comparable to those of the headspace gas chromatography-mass spectrometry system. However, the variability in individual concentrations was still large, due to the unstable control of sample injection flow and pressure. Herein, 79% of the 28 compounds met one-tenth of the proposed method detection limit criteria for emergency operations in WWTP. Field experiments showed that the system was easy to maintain and could be used to monitor chemical accidents.

The time has come to extend the expiration limit of cryopreserved allograft heart valves.

Despite the wide choice of commercial heart valve prostheses, cryopreserved semilunar allograft heart valves (C-AHV) are required, and successfully transplanted in selected groups of patients. The expiration limit (EL) criteria have not been defined yet. Most Tissue Establishments (TE) use the EL of 5years. From physiological, functional, and surgical point of view, the morphology and mechanical properties of aortic and pulmonary roots represent basic features limiting the EL of C-AHV. The aim of this work was to review methods of AHV tissue structural analysis and mechanical testing from the perspective of suitability for EL validation studies. Microscopic structure analysis of great arterial wall and semilunar leaflets tissue should clearly demonstrate cells as well as the extracellular matrix components by highly reproducible and specific histological staining procedures. Quantitative morphometry using stereological grids has proved to be effective, as the exact statistics was feasible. From mechanical testing methods, tensile test was the most suitable. Young's moduli of elasticity, ultimate stress and strain were shown to represent most important AHV tissue mechanical characteristics, suitable for exact statistical analysis. C-AHV are prepared by many different protocols, so as each TE has to work out own EL for C-AHV.

Performance of local level planning policies for reducing greenhouse gases: insight from new buildings in Scotland

PurposeThe purpose of the study is to assess performance of local level planning policies that required new buildings to avoid a specified and rising proportion of projected greenhouse gases (GHGs) from their use; it is calculated based on the approved design and plans for the specific development and through the installation and operation of low and zero-carbon generating technologies (LZCGTs).Design/methodology/approachData were extracted from a random sample of 911 new builds from 403 planning applications and related documents, across five Scottish local planning authorities (LPAs) who adopted GHG reduction policies. The data included GHG reduction, LZCGT installation and performance, use of plan designs to meet GHG reductions and exemptions from the GHG policies. Descriptive statistics using SPSS software, complimented by qualitative responses from questionnaires, helped to explain observed performance.FindingsThe policies performed poorly, at the level of delivering low-hanging fruits, with significant room for improvement. Design-led opportunities in the GHG policies were not actively pursued; most LZCGT installation was exempted from GHG policies and the policies were poor in targeting the relationship between building unit size, GHG emission and reductions.Research limitations/implicationsThe source documents, where the data came from, had varying quality and completeness and some LPAs are over-represented in the data. The study applied limited criteria to evaluate policy performance.Practical implicationsAreas for policymakers to further focus on when exploring how to enhance role and performance of LZCGT are highlighted, including practical suggestions.Originality/valueOne of the few studies assessing policy performance and distilling lessons, from early adopters of GHG policies at local level planning, offer performance benchmarks and raise points of concern for policymakers.

FIT OF STATISTICAL FORECASTING MODEL BERDASARKAN VARIABEL ANGKA KEMISKINAN DI PROVINSI KEPULAUAN BANGKA BELITUNG

Poverty is one of the main problems in economic development and is considered to be a variable to measure the success of the economic development of a region. This study is limited to the analysis and determination of the best forecasting statistical model for the variable poverty rate in the Bangka Belitung Islands Province area based on R Square, Root Mean Squared Error (RMSE) and Mean Absolute Percentage Error (MAPE) assessments. This study uses the Exponential Smoothing forecasting method which emphasizes the procedure of continuous improvement of the latest observation objects which hopefully can provide the appropriate results. In general, the double exponential smoothing model from Holt's is the best projection model compared to other exponential smoothing models for projecting poverty data in the Bangka Belitung Islands Province with historical data for 2002-2018 with an increase in projections in 2019 of 0.37 % with Upper Criteria Limit (UCL) of 1.07% and Lower Criteria Limit (LCL) of -0.33% with a value of R Square of 0.627 which means that the independent variable can explain the variance of the dependent variable of 62.7% of this model, and the value of RMSE is 0.328 and MAPE is 22.162. The results of this model when compared to other models have relatively larger R Squared values ??and smaller RMSE and MAPE values.

How can the urban landscape affect urban vitality at the street block level? A case study of 15 metropolises in China

Urban vitality, as a metric, measures the attractiveness and competitiveness of a city and is a driver of development. As the physical and social space of human activities, the urban landscape has close connections with urban vitality according to classical theories. However, limited quantitative criteria for the urban landscape and gaps between macro urban planning and micro design create difficulties when constructing a vibrant city. In this study, we quantitatively examined the relationship between the urban landscape and urban vitality at the street block level using geospatial open data to discover where, how, and to what extent we could improve urban vitality, taking 15 Chinese metropolises as a case study. Results indicate that, among the three aspects of the urban landscape considered, the city plan pattern has the highest effect on stimulating vitality, followed by the land use and the patterns of building form. Specifically, the three-dimensional form of buildings has a greater effect than a two-dimensional form. In addition, convenient transportation, a compact block form, diverse buildings, mixed land use, and high buildings are the main characteristics of vibrant blocks. The results also show that the effects of the urban landscape have spatial variations and obvious diurnal discrepancies. Furthermore, over 20 and 33% of the blocks in these cities are identified as low-vitality blocks during the day and night, respectively, and are then categorized into six different types. The identification of the common characteristics of these low-vitality blocks can be taken as references for designing a vibrant urbanity.

Reasons for Low Utilization of Pancreas for Transplantation From Deceased Donors: Analysis of Data From a Single Center in India

ObjectivesAlthough pancreas transplants were started at our center in 2014, the number of pancreases procured have remained low. This report presents an audit of donors over the past 18 months with the aim to identify factors preventing pancreas utilization. MethodsThis was a retrospective study. All deceased donors from January 2018 to July 2019 were included in this study. The medical records of deceased donors were reviewed with regard to donor characteristics such as demographics, biochemical parameters, and preterminal management. ResultsOrgans were retrieved from 49 deceased donors over the duration of the study. Mean age of the donors was 35.34 ± 18.2 years (11 months to 72 years). Most donors were men (M:F 41:8). In total, 45/49 (92%) donors had central nervous system trauma as a cause of brain death. Out of 49, multiple abdominal organs were retrieved from 21 donors (42.8%), whereas kidneys alone were retrieved from the rest. Pancreases were retrieved from 8 donors (16.3%). Pancreases were rejected in 21 donors (42.8%) because of age limit criteria. Other reasons for refusal included donor sepsis (n = 12, 24.5%), severe hemodynamic instability (n = 5, 10.2%), donation after cardiac death (DCD) (n = 2, 4.1%), and ischemic hepatitis (n = 7, 14.3%) while 3 (6.1%) donations happened while awaiting license renewal. A suitable recipient was not available for 1 donor (2.0%). ConclusionPancreas retrieval rates remain low because of donor-related factors. Expansion of age limits and better donor management could improve pancreas transplant activity.

Estimating the number of traffic crash-related cervical spine injuries in the United States; An analysis and comparison of national crash and hospital data

BackgroundCervical spine injury is a common result of traffic crashes, and such injuries range in severity from minor (i.e. sprain/strain) to moderate (intervertebral disk derangement) to serious and greater (fractures, dislocations, and spinal cord injuries). There are currently no reliable estimates of the number of crash-related spine injuries occurring in the US annually, although several publications have used national crash injury samples as a basis for estimating the frequency of both cervical and lumbar spinal disk injuries occurring in lower speed rear impact crashes. PurposeTo develop a reliable estimate of the number of various types of cervical spine injuries occurring in the US by comparing data from national crash injury to national hospital ED and inpatient samples. Study DesignComparative cross-sectional MethodsCervical spine injury data were accessed, analyzed, and compared from 3 national databases; the National Automotive Sampling System-Crashworthiness Data System (NASS-CDS), Nationwide Emergency Department Sample (NEDS), and the Nationwide Inpatient Sample (NIS). ResultsIt is estimated that there are approximately 869,000 traffic crash-related cervical spine injuries seen in hospitals in the US annually, including around 841,000 sprain/strain (whiplash) injuries, 2800 spinal disk injuries, 23,500 fractures, 2800 spinal cord injuries, and 1500 dislocations. Because of a highly restrictive inclusion criteria for both crash and injury types, as well as a very small sample size, the NASS-CDS underestimated all types of crash-related cervical spine injuries seen in US hospital emergency departments by 84 %. The injury type with the largest degree of underestimation in the NASS-CDS was cervical disk injuries, which were estimated at an 88 % lower frequency than in the NEDS. National insurance claim data, which include cases of cervical disk injury diagnosed both in and outside of the ED, indicate that the NEDS likely undercounts cervical disk injuries by 92 %, and thus the NASS-CDS correspondingly undercounts such injuries by 99 % or more. ConclusionsBecause of a limited sample size and restrictive criteria for both crash and injury inclusion, the NASS-CDS cannot be used to estimate the number of crash-related spinal injuries of any type or severity in the US. The most inappropriate use of the database is for estimating the number of spinal injuries resulting from low speed rear impact collisions, as the NASS-CDS samples fewer than 1 in 100,000 of the cervical spine injuries of any type occurring in low speed rear impact collisions.

Consenso de grupo Ad-hoc sobre recomendaciones para la evaluación y controles de calidad para el diagnóstico molecular y serológico de la infección humana por SARS CoV-2

Se formulan recomendaciones de un grupo de consenso de expertos sobre los criterios para evaluar el desempeño diagnóstico (tamaño y selección de muestras para sensibilidad y especificidad analíticas, criterios para establecer límites de detección, criterios para establecer el estándar de oro para las serologías) que deberían ser tenidos en cuenta al evaluar y validar las pruebas diagnósticas para SARS CoV-2. Con el propósito de asegurar la calidad de las pruebas serológicas a utilizar en el país, se recomienda la participación en un programa de control de calidad externo, que garantice la idoneidad y desempeño en la realización de las pruebas diagnósticas serológicas y moleculares durante esta pandemia, ya que su uso tiene profundas implicaciones para las medidas de intervención clínicas individuales y de seguimiento y control en salud pública.

Numerical and Experimental Investigation of the Design of a Piezoelectric De-Icing System for Small Rotorcraft Part 3/3: Numerical Model and Experimental Validation of Vibration-Based De-Icing of a Flat Plate Structure

The objective of this research project is divided in four parts: (1) to design a piezoelectric actuator-based de-icing system integrated to a flat plate experimental setup and develop a numerical model of the system with experimental validation, (2) use the experimental setup to investigate actuator activation with frequency sweeps and transient vibration analysis, (3) add an ice layer to the numerical model and predict numerically stresses at ice breaking with experimental validation, and (4) bring the concept to a blade structure for wind tunnel testing. This paper presents the third part of the investigation in which an ice layer is added to the numerical model. Five accelerometers are installed on the flat plate to measure acceleration. Validation of the vibration amplitude predicted by the model is performed experimentally and the stresses calculated by the numerical model at cracking and delamination of the ice layer are determined. A stress limit criteria is then defined from those values for both normal stress at cracking and shear stress at delamination. As a proof of concept, the numerical model is then used to find resonant modes susceptible to generating cracking or delamination of the ice layer within the voltage limit of the piezoelectric actuators. The model also predicts a voltage range within which the ice breaking occurs. The experimental setup is used to validate positively the prediction of the numerical model.

Fatures of the optimal composition of a wind-solar power plant with diesel generators

The article presents the results of a single-purpose optimization of the composition of the hybrid complex consist of the wind-solar and diesel power plants, according to the criterion of the minimum cost of electricity for a small settlement in given geographical conditions. An estimation of the impact of an additional criterion for the total investment cost limitation on a result of solving an optimization problem is given. It is shown that the ratio of the proportions of the solar and wind power plants is not constant when total investment cost changes and it changes to the exclusion of one of the renewable energy sources from the complex.

Representativeness of the PIONEER-HF Clinical Trial Population in Patients Hospitalized With Heart Failure and Reduced Ejection Fraction.

In PIONEER-HF (Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-pro BNP in Patients Stabilized From an Acute Heart Failure Episode), the in-hospital initiation of sacubitril/valsartan in patients hospitalized for acute decompensated heart failure (ADHF) was well-tolerated and led to improved outcomes. We aim to determine the representativeness of the PIONEER-HF trial among patients hospitalized for ADHF using real-world data. The study population was derived from all patients discharged alive for ADHF in the Get With The Guidelines-HF registry from 2006 to 2018 with HF with reduced ejection fraction (HFrEF; all HFrEF with ADHF). We then determined the proportion of patients meeting PIONEER-HF eligibility criteria (PIONEER-HF eligible) and those meeting a set of limited eligibility criteria (actionable cohort). Rates of HF readmissions and all-cause mortality were then compared between the all HFrEF with ADHF, PIONEER-HF eligible, and actionable cohorts using linked Medicare claims data. A total of 99 767 patients with HFrEF in Get With The Guidelines-HF were hospitalized for ADHF. PIONEER-HF inclusion criteria were met by 71 633 (71.8%) patients, and both inclusion and exclusion criteria were met by 20 704 (20.8%) patients. Further, 68 739 (68.9%) patients met the criteria for the actionable cohort. Among the Centers for Medicare and Medicaid-linked patients, the HF rehospitalization rate at 1 year was 35.1% (95% CI, 34.5-35.8) for all HFrEF with ADHF patients, 32.6% (95% CI, 31.3-33.9) for the PIONEER-HF eligible cohort, and 33.1% (95% CI, 32.3-33.9) for the actionable cohort. The 1-year all-cause mortality was 36.7% (95% CI, 36.1-7.4) for all HFrEF with ADHF patients, 31.6% (95% CI, 30.3-32.9) for the PIONEER-HF eligible cohort, and 32.2% (95% CI, 31.4-33.0) for the actionable cohort. Patient characteristics and clinical outcomes for patients eligible for PIONEER-HF only modestly differ when compared with those encountered in routine practice, suggesting that the in-hospital initiation of sacubitril/valsartan should be routinely considered for patients with HFrEF hospitalized for ADHF.

Prevertebral Soft-Tissue Swelling at C7 Is Highly Sensitive for Cervical Spine Ligamentous Injury Study Type: Retrospective Cohort Study.

Objective:To determine the diagnostic potential of prevertebral soft-tissue (PVST) swelling in cervical spine ligamentous injury (LI).Background:PVST swelling in the cervical spine is a historical indicator of cervical spine injury; however, at present, there are no limited objective criteria to use PVST swelling to guide clinical decision-making regarding cervical spine LI. This study investigates PVST thickness as a screening measure for cervical spine LI with a potential to identify indications for advanced imaging.Methods:The registry at an urban level 1 trauma center was queried for cervical spine injuries between 2010 and 2016. Twenty-nine patients with LIs who had both CT and MRI available were included. Fifty-nine patients with bony injury (BI) were also included, and 99 patients undergoing CT of the cervical spine after blunt trauma without evidence of cervical spine injury were included as control patients.Results:PVST swelling >11.5 mm at C7 was 89.7% sensitive (72.7% to 97.8%) and 51.5% specific (41.3% to 61.7%) for LI. In men, a PVST thickness of 11.5 mm at C7 was 96% sensitive (79.7% to 99.9%) and 46.2% specific (32.2% to 60.5%) for LI. Patients with LI were more likely to be men (86.2% versus 52.5% control, P < 0.01). 86.2% of patients with LI (25 of 29) had associated BI. Patients who had LI and no associated BI (n = 4) were all men, and all had PVST thickness >11.5 mm at C7 (avg. PVST 17.7 mm ± 2.5).Conclusion:C7 PVST thickness >11.5 mm was highly sensitive but poorly specific for cervical spine LI. This threshold may represent an appropriate PVST thickness to rule out LI because patients with PVST ≤11.5 mm are unlikely to have cervical spine LI and may not benefit from MRI.

A lower flammability limit prediction model of alkane-CO2 mixtures based on flame phenomenon simulation

In the present study, a novel model is proposed to evaluate the lower flammability limit (LFL) of alkane diluted with CO2. The LFL model is based on flame phenomenon simulation (FS-LFL). The model consists of combustion, turbulence, and igniter models, which are used to characterise the combustion based on the chemical kinetics and CFD, which is not feasible with traditional methods. The flame simulation phenomenon was validated by contrast with experiment and same criterion of flammability limit in the experiment was adopted. The FS-LFL model was used to predict the LFLs of a propane-CO2 mixture and propane at various temperatures. The model performance was analysed by comparing the results with experimental data and predictions obtained from existing methods. The AARDs between the predicted and experimentally determined LFLs of the propane-CO2 mixture are 0.34%, 1.19%, and 1.35% at 30°C, 50°C, and 70°C, respectively. The model also has a good predictive power with respect to the LFLs of propane at initial temperatures ranging from 30°C-300°C, with an AARD of 2.10%. When the dilution of CO2 is 90%, the model yields a better result due to the utilisation of the chemical kinetics mechanism. This result is instructive for the use of this method in the prediction of upper flammability limits.

The characteristics of neonatal sepsis in Low Birth Weight (LBW) infants at Sanglah General Hospital, Bali, Indonesia

Backgrounds: Neonatal sepsis is a significant cause of mortality and long-term morbidity. The preterm infant has high-risk sepsis and its sequelae. Low birth weight infants were more susceptible to sepsis. Initial infections in neonates may not be identified due to non-specific symptoms and sign with the limited laboratory criteria. This study aims to describe the characteristics of neonatal sepsis in low birth weight infants in the neonatology intensive care unit of Sanglah Hospital.Methods: A retrospective cross-sectional study was conducted among 168 infants aged zero to 28 days with birth weights &lt;2,500 grams from May 2017 – April 2018 at Sanglah General Hospital, Bali, Indonesia using a purposive sampling technique. The inclusion criteria were sepsis infants who were hospitalized in neonatology care rooms during the study period at Sanglah General Hospital. Variables assessed in this study were sex, location and mode of delivery, birth weight, gestational age, number of parity, length of stay, the onset of sepsis, as well as the outcome. Data were analysed using SPSS version 17 for Windows.Results: The mortality rate of sepsis in low birth weight infants was 29.8%. Most of the subjects were male (53%), location of delivery at Sanglah Hospital (60.7%), born spontaneously (51.2%), birth weight were 1500-2499 grams (58,3%) and the most gestational ages were 32-36 weeks (44,6%). Early-onset neonatal sepsis (EONS) dominates patients with neonatal sepsis, with a mean length of stay was 23.27±20.32 days. The major infection risk factor was premature rupture membrane (PRM) &gt;24 hours (14.9%), and minor infection risk factor was gestational age &lt;37 weeks (78%), very low birth weight (44.6%) and asphyxia (41.1%). The total blood culture positivity was 38 (22.6%) cases, and Enterococcus faecalis was the most common organism in this study.Conclusion: The incidence and mortality of neonatal sepsis in LBW infants were still high. The importance of knowledge and awareness of pregnant women about danger signs and the risk of infection can reduce the incidence of early-onset neonatal sepsis. Prevention of healthcare-associated infections can reduce the incidence of late-onset neonatal sepsis.