This work is a comprehensive review of modern aspects of the diagnosis and treatment of endocrine disorders and their impact on reproductive health. The basic principles of the functioning of the human endocrine system are highlighted, including the role of hormonal balance in maintaining the health and functioning of the reproductive system. Various types of endocrine disorders and their effects on reproductive health are also being investigated. In particular, conditions such as hypothyroidism, hyperthyroidism, polycystic ovary syndrome (PCOS), hyperprolactinemia and diabetes, their symptoms, diagnosis and treatment are highlighted. Special attention is paid to the relationship between endocrine disorders and infertility, as well as methods of correcting hormonal imbalances to restore reproductive function. In addition, modern methods of diagnosis and treatment of endocrine disorders are discussed, including laboratory and instrumental methods, molecular genetic studies, as well as advanced approaches in pharmacological therapy, surgical interventions and alternative methods such as active surveillance and lifestyle changes.