This volume presents the written contributions of the participants of the V Workshop on Modeling and Simulation for Science and Engineering (V WMSSE) which was held from July 25 to 26, 2022, at the Bogotá city, Colombia, organized by the Foundation Of Researchers In Science And Technology Of Materials (FORISTOM).The Proceedings volume includes 12 manuscripts that were presented as plenary talks at the conference; the abstracts of all participants’ contributions were published in the Book with ISSN 2745-1496. The website of the conference is available at https://foristom.org/5wmsse.The two-day scientific program of the V WMSSE consisted of 5 plenary lectures, 12 oral on-site presentations, and 26 virtual presentations, with the participation of undergraduate and graduate students, professors, researchers, and entrepreneurs from Spain, Mexico, Uruguay, Brazil, Ecuador, and Colombia.Likewise, the main aim of V WMSSE was to bring together national and international researchers in order to show scientific progress and to highlight the strong correlation of research in modeling and simulation on science, engineering, nanotechnology, and industrial applications; besides, to promote the exchange of creative ideas and the effective transfer of scientific knowledge, from fundamental research to innovation applied to industrial solutions with of purpose to advance in the development of the society by means of efficient transference of the knowledge between sectors academia and industry.All papers in these Proceedings volume refer to one of the following topics covered in the V WMSSE:✓ Computer Science.✓ Mechatronic Systems.✓ Dynamic Systems Modeling.✓ Physical-Chemistry Modeling.✓ Physics-Mathematical Modeling.✓ Modeling, Simulation, and Diagnostics.✓ Education on Science, Engineering, and Technology.On behalf of the organizing committee of the V WMSSE, we are extremely thankful to all authors and participants for providing their valuable contributions for this Proceedings volume as well as the reviewers for their constructive recommendations and criticism aiding to improve the presented articles.List of Organizing Committee, National Scientific Committee, International Scientific Committee, Invited Speakers, Sponsor, Partners are available in this Pdf.