Adhesion Model Research Articles

Dynamic Numerical Simulation of Curved Surface Coating Trajectory Based on STL Slicing Algorithm

The thickness of the coating on the surface of a workpiece is an important factor in determining the quality of spraying. However, it is challenging to estimate the distribution of film thickness accurately before the actual spraying process. This lack of estimation hinders the optimization of spraying process parameters and trajectory. To overcome this, a numerical simulation of surface spray coating thickness was conducted to provide guidance for the actual coating process. The research consists of three main parts. Firstly, the spray trajectory of the spray gun is determined using the proposed Stereo Lithography (STL) model slicing algorithm. Secondly, a two-phase flow spray model and collision adhesion model are established to construct the spray film model. The surface mesh is determined, and the spraying process parameters are set. Finally, numerical simulation is conducted to analyze the dynamic spraying trajectory and the distribution of coating thickness. The results show that the coating thickness distribution on an arc surface is thicker in the middle and thinner on the edges. The distribution is symmetric with respect to both the transverse and longitudinal directions of the arc surface. The coating thickness distribution at both ends is not as uniform as in the middle section. The concave part of the free surface has the largest coating thickness, while the coating thickness distribution on the convex part is not as uniform as on the relatively flat part. This method of simulating the coating thickness distribution on complex surfaces provides a solid foundation for further optimization of spraying process parameters and trajectory, ultimately improving the qualification rate of workpiece spraying processing.

Histological study of telocytes in mice intrauterine adhesion model and their positive effect on mesenchymal stem cells in vitro.

Intrauterine adhesions (IUA), the main cause of secondary infertility in women, result from irreversible fibrotic repair of the endometrium due to inflammation or human factors, accompanied by disruptions in the repair function of endometrial stem cells. This significantly impacts the physical and mental health of women in their childbearing years. Telocytes (TCs), a distinctive type of interstitial cells found in various tissues and organs, play diverse repair functions due to their unique spatial structure. In this study, we conduct the inaugural exploration of the changes in TCs in IUA disease and their potential impact on the function of stem cells. Our results show that in vivo, through double immunofluorescence staining (CD34+/Vimentin+; CD34+/CD31-),as endometrial fibrosis deepens, the number of TCs gradually decreases, telopodesshorten, and the three-dimensional structure becomes disrupted in the mouse IUA mode. In vitro, TCs can promote the proliferation and cycle of bone mesenchymal stem cells (BMSCs) by promoting the Wnt/β-catenin signaling pathway, which were inhibited using XAV939. TCs can promote the migrated ability of BMSCs and contribute to the repair of stem cells during endometrial injury. In addition, TCs can inhibit the apoptosis of BMSCs through the Bcl-2/Bax pathway. In conclusion, our study demonstrates, for the first time, the resistance role of TCs in IUA disease, shedding light on their potential involvement in endometrial repair through the modulation of stem cell function.

Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm.

Convergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general features of cell-cell contacts in this tissue by combining depletion of adhesion factors C-cadherin, Syndecan-4, fibronectin, and hyaluronic acid, the analysis of respective contact width spectra and contact angles, and La3+ staining of the pericellular matrix. We provide evidence that like in other gastrula tissues, cell-cell adhesion in the chordamesoderm is largely mediated by different types of pericellular matrix. Specific glycocalyx structures previously identified in Xenopus gastrula tissues are absent in chordamesoderm but other contact types like 10-20 nm wide La3+ stained structures are present instead. Knockdown of any of the adhesion factors reduces the abundance of cell contacts but not the average relative adhesiveness of the remaining ones: a decrease of adhesiveness at low contact widths is compensated by an increase of contact widths and an increase of adhesiveness proportional to width. From the adhesiveness-width relationship, we derive a model of chordamesoderm cell adhesion that involves the interdigitation of distinct pericellular matrix units. Quantitative description of pericellular matrix deployment suggests that reduced contact abundance upon adhesion factor depletion is correlated with excessive accumulation of matrix material in non-adhesive gaps and the loss of some contact types.

Electrical detachment of bumpy particles and rough spherical particles charged by corona ions

ABSTRACT Electrostatic detachment of bumpy and spherical particles with rough surfaces charged by corona ions was studied. Corona charging leads to uniformly distributed charges across the entire particle surface. The JKR adhesion model and electrostatic interactions of these particles in contact with a surface were evaluated. The electrostatic forces for particles carrying fixed charges per unit mass were evaluated. The study investigated the electric fields required to detach charged particles from rough surfaces for different charge levels, various numbers of bumps for bumpy particles, and different numbers of contact asperities for rough spherical particles. The accuracy of the model predictions for detaching charged particles from substrates with varying degrees of roughness was assessed by comparison with the experimental data, which indicated that the predicted electric detachment fields agreed with the experimental data for the selected range of parameters. The proposed model provides a helpful framework for removing bumpy particles, and rough spherical particles charged by corona ions in various applications. For 8.3 μm polystyrene charged latex particles, approximately 46% and 62% reductions in detachment electric field were found for a 10% decrease in the roughness parameter for bumpy particles and rough spheres, respectively.

Investigation on tillage resistance and soil disturbance in wet adhesive soil using discrete element method with three-layer soil-plough coupling model

To reveal the interaction between plough and wet adhesive soil, it's essential to establish an accurate coupling model of the soil-plough system. Traditional Edinburgh elasto-plastic adhesive contact model neglects the adhesion effect when two interactive particles are separated, leading to lower simulation accuracy. Here, an improved contact model of wet adhesive soil by introducing the adhesive force is proposed. Then a novel discrete element model of a three-layer soil-plough coupling system is established, where the liquid bridge force and the adhesion effect are considered. Furthermore, the corresponding soil bin tests are also conducted to demonstrate the effectiveness of the proposed model. Finally, the effect of soil adhesion, ploughing speeds and ploughing depths on the tillage resistance and soil disturbance is analyzed. Results show that the prediction accuracy of the proposed model increases by about 7%, moreover, the soil disturbed area decreases, while the tillage resistance increases with increasing soil adhesion.

Establishment and comparison of different procedures for modeling intrauterine adhesion in rats: A preliminary study

The establishment of a stable animal model for intrauterine adhesion (IUA) can significantly enhance research on the pathogenesis and pathological changes of this disease, as well as on the development of innovative therapeutic approaches. In this study, three different modeling methods, including phenol mucilage combined mechanical scraping, ethanol combined mechanical scraping and ethanol modeling alone were designed. The morphological characteristics of the models were evaluated. The underlying mechanisms and fertility capacity of the ethanol modeling group were analyzed and compared to those of the sham surgery group. All three methods resulted in severe intrauterine adhesions, with ethanol being identified as a reliable modeling agent and was subsequently subjected to further evaluation. Immunohistochemistry and RT-PCR results indicated that the ethanol modeling group exhibited an increase in the degree of fibrosis and inflammation, as well as a significant reduction in endometrial thickness, gland number, vascularization, and endometrial receptivity, ultimately resulting in the loss of fertility capacity. The aforementioned findings indicate that the intrauterine perfusion of 95 % ethanol is efficacious in inducing the development of intrauterine adhesions in rats. Given its cost-effectiveness, efficacy, and stability in IUA formation, the use of 95 % ethanol intrauterine perfusion may serve as a novel platform for evaluating innovative anti-adhesion materials and bioengineered therapies.

A transient three-dimensional wheel-rail adhesion model under wet condition considering starvation and surface roughness

The objective of this paper is to propose a new three-dimensional wheel-rail adhesion model under wet condition which considers insufficient water supply, the measured surface roughness and dynamic effect of the vehicle and track coupling system. Firstly, a longitudinal vehicle/track coupling dynamic model (LVTDM) was developed to obtain the dynamic parameters and contact points trace in curved track. Then, an improved numerical method was used to solve the transient general starved Reynolds equations, utilizing the input dynamic parameters acquired from the LVTDM. The numerical model was validated under the starved steady condition for the smooth surface and subsequently applied to investigate wheel and rail contact behaviors under wet condition. The results show that the effect of starvation on the wheel-rail rolling contact behaviours becomes significant when the inlet film thickness is less than 1000 nm for smooth surface. The numerical results were also compared with experimental results conducted by a high-speed tribology facility. In addition, the time-dependent characteristics of the wheel-rail rolling contact were obtained at different time instants. The transient wheel-rail adhesion characteristics under wet condition for different train speeds were obtained. The transient wheel-rail adhesion modeling results shows that the train speed has a significant effect on the adhesion ability.

Cytotoxic effect of the VVGMCSF-Lact oncolytic virus against 3D cultures of human glioblastoma cells U-87 MG

Background. One of the promising methods of treating tumors is virotherapy, which is based on direct lysis of cancer cells by a virus and a virus-mediated antitumor immune response of the body. For the recombinant vaccinia virus strain VVGMCSF-Lact, producing human GMCSF and the oncotoxic protein lactaptin, cytotoxic and antitumor effects were shown in experiments in vitro and in vivo, respectively, when using adhesive cultures of U-87 MG human glioblastoma cells. 3D cultures are a more relevant tumor model than adhesive models, as they more fully reflect the realistic scenario of cancer development, as well as the response of the tumor to anticancer therapy.The aim. To evaluate the cytotoxic effect of the oncolytic virus VV-GMCSF-Lact against 3D cultures of human glioblastoma U-87 MG.Materials and methods. The following methods were used in the work: cultivation of 3D cell cultures, cytofluorometry, microscopic analysis, virus titration, statistical analysis.Results. U-87 MG cells were transduced with a lentiviral vector carrying the GFP reporter gene. The cytotoxicity of the VV-GMCSF-Lact virus (IC50) against the studied cells was 0.024 PFU/cell. U-87 MG cells were cultured under conditions for the formation of 3D structures. Microscopic analysis showed the oncolytic effect of the virus on the cells of 3D cultures as early as 24 hours after the start of incubation. Flow cytometry showed an increase in the granularity of glioblastoma cells under the action of the virus, which indicates active replication of the virus in the cells. The virus titer was 0.44 PFU/cell.Conclusions. The recombinant VV-GMCSF-Lact virus has a cytotoxic effect on 3D human glioblastoma U-87 MG cell cultures and actively replicates in them. In the future, to test the oncolytic effect of VV-GMCSF-Lact, it is planned to use not only 3D human glioblastoma cultures, but also cerebral organelles obtained in the process of cocultivation of glioblastoma cells and induced human pluripotent cells.

Analysis of adhesive contact of heterogeneous elastic materials

This paper reports a three-dimensional numerical model to solve adhesive elastic contact problem of heterogeneous materials with an engineered rough surface. This model integrates the Maugis-Dugdale (MD) adhesive contact model, the Boussinesq-Cerruti integral equations, the equivalent inclusion method (EIM), and the discrete convolution and fast Fourier transform (DC-FFT) algorithm, aiming at accurate determination of contact results for heterogeneous materials. An adhesive displacement-driven conjugate gradient method (CGM) was also developed to support rapid solutions of contact pressure and contact area. Four cases were analyzed to verify this model with satisfaction. This model was used to analyze the effects of inhomogeneity (location, size, and material properties) and adhesion on micro-adhesive-elastic contact, and the results lead to a curve-fitting equation for quick evaluation of the effects of inhomogeneity properties and adhesion characteristics on normal traction. It was also utilized to study the influence of the roughness level of a type of rough surface on the surface adhesion behavior.

CircABCC1 reduces endometrial receptivity via METTL3/FAM155B axis.

Impaired endometrial receptivity is the main cause of embryo implantation failure. Little information is available on the role of circRNAs in endometrial receptivity. Here, the effect of circABCC1 on endometrial receptivity and its mechanism were investigated. GEO database was screened for key biomarkers for recurrent implantation failure (RIF). Endometrial epithelial cells (EECs) were cultured and transfected with circABCC1- and/or FAM155B-related vectors, followed by CCK-8 detection of cell proliferation, western blotting detection of receptivity-related factors LIF and DKK1, and ELISA detection of LIF secretion. An in vitro adhesion model was established to detect trophoblast adhesion to EECs. RIP was used to detect the binding of METTL3 to circABCC1 and FAM155B mRNA, and MeRIP-qPCR was used to detect m6A modification of FAM155B mRNA. CircABCC1 and FAM155B were highly expressed in patients with RIF. CircABCC1 or FAM155B overexpression reduced EEC proliferation, LIF and DKK1 expression, LIF secretion, and trophoblast adhesion; circABCC1 or FAM155B knockdown led to the opposite results. CircABCC1 and METTL3 positively regulated FAM155B expression. METTL3 bound circABCC1 and FAM155B mRNA. METTL3 overexpression increased m6A modification of FAM155B mRNA. FAM155B overexpression partially eliminated circABCC1 knockdown-induced promotion of EEC proliferation, LIF and DKK1 expression, LIF secretion, and trophoblast adhesion. CircABCC1 binds to METTL3 to regulate FAM155B mRNA modification and promote FAM155B expression, thereby inhibiting EEC proliferation and reducing endometrial receptivity.

Adhesion theory and model for air humidity impact on dust emission

It has been suggested that air humidity influences dust emission under very dry conditions and adhesion might be the responsible process which changes the binding between soil particles. The process of adhesion is so far poorly understood and difficult to quantify. Here, a critical examination of the relevant studies is provided, and an adhesion model is proposed. Both isothermal-kinematic and diffusion processes can limit the soil liquid–water and water–vapor exchange in soil, but for the particle size range concerned in aeolian studies, diffusion appears to be the limiting process. The model shows that soil moisture in the topsoil layers is positively correlated with air humidity, but with delays of several hours. The model performance is influenced by several parameters but is particularly sensitive to the equilibrium soil water–vapor content. This implies that soil microscopic properties can strongly influence adhesion. A new formulation of soil water retention function covering the entire soil moisture range is also proposed, which links soil water retention function and pore size distribution. Using a relationship between soil particle-size and pore-size distributions, an adhesion-affected grain size can be estimated, which defines the upper size limit of soil particles influenced by soil moisture. This study explains how air humidity influences soil moisture through adhesion and dust emission and why low air humidity promotes the emission of finer dust particles.

Effect of intra-abdominal boric acid in the experimental adhesion model.

The continuous advancement in medical and surgical techniques has led to a rise in the frequency of abdominal operations, subsequently increasing the incidence of intra-abdominal adhesions. Over 90% of laparotomies result in postoperative intra-abdominal adhesions. This study investigates the effect of a 5% boric acid solution on the development of intra-abdominal adhesions in rats, using an adhesion model. This study was conducted with two groups: a control group, in which the adhesion model was applied without any treatment, and a boric acid group, which was treated with a 5% boric acid solution. Each group comprised 16 rats. On the 14th postoperative day, the rats were sacrificed, re-explored, and the developed adhesions were evaluated both macroscopically and microscopically. The data from macroscopic and microscopic scoring were analyzed using the Mann-Whitney U test in the IBM Statistical Package for the Social Sciences (SPSS) Statistics 24 program. A p-value of less than 0.05 was considered statistically significant. This research was supported by the Manisa Celal Bayar University Scientific Research Projects Commission. A statistically significant difference was observed between the boric acid-treated group and the control group, with the boric acid group showing a significant decrease in adhesion development both macroscopically and microscopically (p<0.05). In the future, boron could play a significant role in reducing and preventing intra-abdominal adhesions after surgery. This investigation could pave the way for further research into the mechanism by which boric acid prevents the development of intra-abdominal adhesions. Moreover, it is imperative to explore the potential side effects of intra-abdominal boron application at the optimum concentration of the solution.

Investigation of the effects of different drugs on the prevention of intrapleural adhesion in a rat model.

The aim of this study was to investigate the antifibrinolytic and anti-inflammatory effects of hesperidin, tenoxicam and enoxaparin on intrapleural adhesions in an experimental rat model. A total of 52 healthy adult male Wistar Albino rats from the same colony were randomly divided into six groups as sham (Group 1), surgical control (Group 2), low-dose hesperidin (Group 3), high-dose hesperidin (Group 4), tenoxicam (Group 5), and enoxaparin (Group 6). All subjects underwent left thoracotomy and except for the sham group, an adhesion model was applied and, postoperatively, the drugs were administered intraperitoneally. On Day 11 postoperatively, the rats were sacrificed and their blood levels of interleukin-1β and interleukin-10 were examined and they were evaluated for pleural adhesion area, adhesion severity score, mesothelial cell proliferation score, mononuclear cell infiltration score, and macrophage infiltration score in the collagen layer. The lowest adhesion area and adhesion severity score were found in Group 6. There was a statistically significant difference between Group 2 and Group 6 and between Group 3 and Group 6 in terms of both parameters (p=0.04 and p=0.02). As for adhesion area, a statistically significant difference was found between Group 5 and Group 6 (p=0.04). Statistically significant differences were also found between Group 2 and Group 5 in terms of mesothelial cell proliferation scores and between Group 1 and Group 4 in terms of mononuclear cell infiltration scores (p=0.03 and p=0.02). Enoxaparin, tenoxicam, and high-dose hesperidin act at different points to prevent adhesion in rats.

Modeling of single-lap joints with auxetic adhesive utilizing homogeneous and heterogeneous bondline microstructures

Producing lightweight structures can be effectively achieved using adhesive bonding that incorporates a high-performance adhesive, eliminating the mechanical joints (rivet, bolts). Here, the proof-of-concept of tailoring the high-performance adhesive using microstructures exhibiting a negative Poisson's ratio (auxetic) is investigated using two single lap joint (SLJ) models developed in ABAQUS/Standard. The SLJ models consist of two rigid adherends that are bonded using either homogeneous or heterogeneous adhesive that produces auxetic response. In homogeneous adhesive, a negative value of Poisson's ratio is defined in the adhesive part of the models. In heterogeneous adhesive, the negative Poisson's ratio is obtained by explicitly building orthogonally-arranged elliptical voids in the adhesive part of the models. In addition, the adherend-adhesive interface is represented by cohesive elements with bi-linear traction-separation rule. The effects of using two different adhesive models and thickness on peel and shear stresses, as well as failure mechanism and joint strength, are evaluated. We found that the effect of auxetic adhesive on SLJ response is more profound in the model using heterogeneous adhesive rather than the homogeneous one, where the joint strength enhancement could achieve 45 % in reference to the baseline model. The heterogeneous adhesive embedded between adherends is able to activate ligaments, the mechanism that could not be obtained using merely homogeneous adhesive. Our proposed modeling strategy can be a starting point to further the modeling approach of bonded joints utilizing auxetic adhesive.

Lattice-based mesoscale simulations and mean-field theory of cell membrane adhesion.

Adhesion of cell membranes involves multi-scale phenomena, ranging from specific molecular binding at Angstrom scale all the way up to membrane deformations and phase separation at micrometer scale. Consequently, theory and simulations of cell membrane adhesion require multi-scale modeling and suitable approximations that capture the essential physics of these phenomena. Here, we present a mesoscale model for membrane adhesion which we have employed in a series of our recent studies. This model quantifies, in particular, how nanoscale lipid clusters physically affect and respond to the intercellular receptor-ligand binding that mediates membrane adhesion. The goal of this Chapter is to present all details and subtleties of the mean-field theory and Monte Carlo simulations of this mesoscale model, which can be used to further explore physical phenomena related to cell membrane adhesion.

Research on Adhesive Quality Control Based on Piezoelectric Dispensing Valve

Non-contact dispensing in the electronics packaging industry is becoming the most widespread dispensing method. The crucial research direction is to achieve accurate flow control for non-contact dispensing technology. However, the whole dispensing process contains fluid-solid coupling and its nonlinear and unstable flow, which makes it difficult to obtain an accurate prediction model for the quality of adhesive points. In this paper, based on the existing theory and the idea of minimum error backpropagation, we compare the experimental data with the theoretical value of adhesive point by subsequent experiments. Finally, a simple and effective adhesive point quality prediction model for non-Newtonian fluids in the dispensing process is obtained. The Taguchi method was used to prove that the maximum error between the predicted adhesive point quality and the experimental value is <10%, which is highly accurate. The Minitab software was used to analyze Taguchi's experimental data, and the sensitivity of dispensing quality to process parameters was ranked as follows: driving voltage > adhesive supply pressure > nozzle heating temperature; this study can be of guidance to the design of dispensing valve structure and dispensing process parameters, and to achieve high speed and high precision flow control.

Effects of pioglitazone and metformin on abdominal adhesion formation in an experimental model.

This study evaluated the use of metformin or pioglitazone in preventing or reducing the development of post-operative intra-abdominal adhesion (PIAA) by employing histopathological, immunohistochemical, and biochemical analyses in an experimental adhesion model. Fifty Wistar-Albino rats were divided into five groups: Group I (Control), Group II (Sham Treatment), Group III (Hy-aluronic Acid), Group IV (Metformin), and Group V (Pioglitazone). Adhesions were induced in the experimental groups, except for the sham group, using the scraping method. After 10 days, rats were euthanized for evaluation. Macroscopic adhesion degrees were assessed using Nair's scoring system. Immunohistochemical and enzyme-linked immunosorbent assay (ELISA) methods were utilized to assess serum, peritoneal lavage, and intestinal tissue samples. Fructosamine, interleukin-6 (IL-6), transforming growth factor-beta (TGF-β), and fibronectin levels were measured in serum and peritoneal lavage samples. The groups exhibited similar Nair scores and Type I or Type III Collagen staining scores (all, p>0.05). Pioglitazone significantly reduced serum IL-6 and TGF-β levels compared to controls (p=0.002 and p=0.008, respectively). Both metformin and pioglitazone groups showed elevated IL-6 in peritoneal lavage relative to controls, while fibronectin levels in the lavage were lower in pioglitazone-treated rats compared to the sham group (all, p<0.005). Pioglitazone, but not metformin, demonstrated a positive biochemical impact on preventing PIAA formation in an experimental rat model, although histological impacts were not observed. Further experimental studies employing different dose/duration regimens of pioglitazone are needed to enhance our understanding of its effect on PIAA formation.

Nature-inspired adhesive systems.

Many organisms in nature thrive in intricate habitats through their unique bio-adhesive surfaces, facilitating tasks such as capturing prey and reproduction. It's important to note that the remarkable adhesion properties found in these natural biological surfaces primarily arise from their distinct micro- and nanostructures and/or chemical compositions. To create artificial surfaces with superior adhesion capabilities, researchers delve deeper into the underlying mechanisms of these captivating adhesion phenomena to draw inspiration. This article provides a systematic overview of various biological surfaces with different adhesion mechanisms, focusing on surface micro- and nanostructures and/or chemistry, offering design principles for their artificial counterparts. Here, the basic interactions and adhesion models of natural biological surfaces are introduced first. This will be followed by an exploration of research advancements in natural and artificial adhesive surfaces including both dry adhesive surfaces and wet/underwater adhesive surfaces, along with relevant adhesion characterization techniques. Special attention is paid to stimulus-responsive smart artificial adhesive surfaces with tunable adhesive properties. The goal is to spotlight recent advancements, identify common themes, and explore fundamental distinctions to pinpoint the present challenges and prospects in this field.

Comparison of adhesion prevention capabilities of the modified starch powder-based medical devices 4DryField® PH, HaemoCer™ PLUS and StarSil® in the Optimized Peritoneal Adhesion Model.

Background and Objectives: The rat Optimized Peritoneal Adhesion Model (OPAM) was developed to provoke adhesion formation with high reproducibility in incidence and extent. In a recent study, the starch-based hemostats 4DryField PH and Arista AH were tested for their capabilities to prevent adhesion formation, the former one certified for adhesion prevention and hemostasis, the latter one only certified for hemostasis. As two further starch-based hemostats, i.e., HaemoCer PLUS and StarSil, have officially been certified for adhesion prevention in the meantime, the present study was conducted to examine their efficacy. Materials and Methods: For this purpose, all three products were applied as a powder that was mixed in situ with saline solution to form a barrier gel. Adhesions were scored using the established macroscopically scoring systems by Lauder and Hoffmann, as well as histopathologically using the score by Zühlke. Animals receiving saline solution solely served as controls. Results: As previously published, 4DryField PH reduced peritoneal adhesions significantly. In contrast, HaemoCer PLUS and StarSil did not lead to a statistically significant reduction of adhesion formation. When comparing 4DryField PH, HaemoCer PLUS and StarSil, 4DryField PH was significantly more effective in preventing peritoneal adhesions. The results of the macroscopic investigation were confirmed by histopathological evaluations. Conclusions: Only 4DryField PH but neither HaemoCer PLUS nor StarSil were capable to effectively prevent adhesion formation, corroborating the assumption that starch-based hemostats do not generally have the capability to act as effective adhesion prevention devices.

高速耕作条件下土壤离散元参数标定

For the problem of lacking reliable values of soil parameters required for dynamic simulation analysis of soil under high-speed tillage, no-tillage soil was taken as the research object and its parameters were calibrated using the discrete element method in this study. The Edinburgh Elasto-Plastic Adhesion (EEPA) model was determined as the soil contact model by obtaining the loading force-deformation relationship through uniaxial sealing compression tests. The regression equation was established using Plackett-Burman test and quadratic orthogonal rotation test, and the interaction effects were analyzed. The measured values of the pile angle and strain were obtained through the pile angle test and the uniaxial seal compression test, and the optimal solution was carried out. Further, the simulated values and the measured values under the optimal parameters were compared and verified, the result showed that the error values were all less than 1%. Finally, the soil model was used for high-speed tillage simulation analysis, and the obtained soil particle displacement and groove width were compared with the measured values. It was found that the ditch width error value was 3.04% and the soil displacement was basically the same. This study proved that the contact model parameters were relatively reliable, which could provide theoretical reference for the dynamic characteristics of soil during high-speed cultivation of no-tillage soil.