Background Instead of using a cement- or screw-retained coupling, a conometric connection can be used. The retention of a single tooth friction-retained connection is dependent on the cone angle, coefficient of friction, push in force and the external load situation. Lateral forces, mainly occurring in the anterior region, can have an impact on the stability of a conical connection. This study was set up to investigate the stability of the conometric connection under dynamic lateral loading. Aim/Hypothesis The aim of the study was to evaluate the retention of a conical connection between cap and abutment loaded with dynamic lateral forces after an initial axial load. Material and Methods Conometric caps (Ankylos size A, Dentsply Sirona Implants) were assembled on conometric abutments (straight and angled) that were screwed into embedded implants. A spherical loading cap was plugged on and the samples were loaded axially (0°). The samples then were subjected to dynamic loading of 100 N (R = 0.1) at 5 Hz in an 82.5° setup for 10,000 cycles. Subsequently, the caps were pulled off to measure the retention of the conometric cap to the conometric abutment. Results After dynamic lateral loading all caps showed sufficient retention to the abutment. No cap was separated from the abutment during the tests. Tukey test shows that there is a significant difference between the retention of the conometric caps to straight and angled abutments (P = 0.05). This difference is related to the different connection geometries at the conometric connection for straight and angled abutments. Conclusions and Clinical Implications The conometric mode of retention is able to withstand lateral forces that are deemed to occur mainly in the anterior region (incisors). This implies that the conometric connection is feasible for use in single-tooth restorations in the anterior jaw segment.