Infant Feeding Mode Research Articles

Maternal Eating Behavior in Low-Income Mothers Influences Attitudes Toward Infant Feeding

ObjectivesEating behavior is established early in life, influences infant development and health, and is likely to originate with the mother. We examined if maternal eating behaviors influenced attitudes towards infant feeding styles and whether these associations differed by infant feeding mode (breastfeeding and formula-feeding). MethodsThis was an observational study in 35 low-income mother-infant dyads. Postpartum women (≥18 years old, 25 ≤ BMI < 40 kg/m2) in the Louisiana Women, Infants, and Children (WIC) program completed the Eating Inventory and Infant Feeding Styles Questionnaire to assess maternal eating behavior (dietary restraint, disinhibition, and perceived hunger) and infant feeding styles (restrictive feeding, responsive feeding, and pressuring/overfeeding), respectively, 8 weeks after delivery. Linear models with fixed effects were computed with maternal age, BMI, and maternal eating behavior as covariates using SPSS (p < 0.05 to indicate significance). ResultsThirty-four % of the mothers were breastfeeding (n = 12) and 66.0% were formula-feeding (n = 23). Infant feeding styles were not predicted by maternal eating behaviors (all p > 0.05). In mothers who breastfed, maternal dietary restraint was positively associated with infant pressuring/overfeeding (β = 0.91, p < 0.05) and was different from those in the formula fed group (Δ = 1.37, p = 0.02). In addition, maternal disinhibition was negatively associated with restrictive infant feeding (β = –0.53, p < 0.05) and was different from those in the formula fed group (Δ = –0.95, p = 0.003). Comparatively, in mothers who formula-fed, restrictive infant feeding was predicted by maternal disinhibition (β = 0.42, p < 0.01; Δ = –0.95, p = 0.003) and maternal perceived hunger (β = 0.43, p < 0.01; Δ = 0.71, p = 0.007). ConclusionsMaternal eating behavior is associated with infant feeding styles only when feeding mode is considered. Interventions educating mothers on how their own eating behaviors have the potential to influence eating behaviors of their children are needed. Funding SourcesUSDA Small Grants Program and the NIH (T32DK064584, and U54 GM104940).

Evaluation of staff knowledge; attitudes and experience of breastfeeding on a mother and baby unit

AimsTo evaluate the knowledge and experience of breastfeeding of staff working on a Mother and Baby Unit (MBU).To assess the level of breastfeeding education of Staff on the MBU.To identify any area of concern around breastfeeding on the MBU.MethodA fourteen question questionnaire was designed with assistance of the medical team, midwife, and health visitor on the unit. The questionnaire was comprised of questions requiring “yes/no” and free text responses alongside Likert scales. The questionnaire focused on staff experience on breastfeeding, education levels and whether they felt Mothers were sufficiently supported. This questionnaire was distributed to all staff groups within the team to ascertain the level of expertise. 29 questionnaires were returned from a staff team of 31.ResultStaff on this unit is made up of Multi-disciplinary professionals. Most respondents were Nursery Nurses (15%). 79% of staff had a lived experience of breastfeeding. Only 5 out of 29 respondents have had any breastfeeding training which was mainly in-house training, and these were the Health Visitor; Midwife and Nursery nurses. Of the respondents, 21% felt mothers who choose breastfeeding as their preferred mode of infant feeding were not adequately supported on the MBU. Seven percent were unsure and 72% felt women were adequately supported. 54% of staff were not aware of breastfeeding initiatives. 63% were able to list contraindications including names of psychotropic medications as well as personal choice and past medical history. The median rating in relation to confidence in skills on Likert scale of 1-10 was 5.Conclusion23 out of 29 professionals felt that Training would increase their confidence and skills in breast feeding support for women admitted to the unit. There is clear indication from the Staff Members that mothers on the MBU who choose breastfeeding as their preferred mode of infant feeding require further support. There is lack of confidence in staff's breastfeeding support in the MBU. An evaluation of patient's own experience of breastfeeding support they receive from staff is being undertaken alongside this, but data will be analysed later.

Modifiable early life exposures associated with adiposity and obesity in 3-year old children born to mothers with obesity.

Children born to mothers with obesity are at increased risk of obesity. Influences underlying this predisposition include in-utero exposures, genetic predisposition and a shared family environment. Effective intervention strategies are needed to prevent obesity in these high-risk children; this requires evaluation of modifiable pregnancy and early-life risk factors. To assess the individual and cumulative contributions of maternal and early-life modifiable exposures on childhood adiposity and obesity outcomes in 3-year-old children born to women with obesity. We used adjusted regression to assess the individual and cumulative contributions of six exposures (early pregnancy BMI, excessive gestational weight gain, mode of infant feeding and three measures of childhood eating habits [food responsiveness, slowness in eating and a processed/snacking dietary pattern score]) on body composition in 495 three-year-old children. Outcomes included BMI z-score, arm circumference and overweight/obesity (BMI≥25.0 kg/m2 ). While the UPBEAT intervention did not influence adiposity outcomes in 3-year-old children, the six modifiable exposures combined incrementally to increase childhood adiposity and obesity. For each additional exposure, children had a higher BMI z-score (β=0.35SD [95% confidence interval: 0.23, 0.47]), arm circumference (β=0.59 cm [0.40, 0.79]) and risk of overweight/obesity (relative risk 1.49 [1.26, 1.77]). Compared to no exposures, children with four or more exposures had a higher BMI z-score (1.11SD [0.65, 1.58]), arm circumference (2.15 cm [1.41, 2.89]) and risk of overweight/obesity (3.01 [1.67, 5.41]) (all P < 0.001). Our findings suggest that complex interventions targeting preconception, pregnancy, perinatal and early childhood exposures offer a potential strategy for prevention of pre-school obesity.

Why is the Incidence of Type 1 Diabetes Increasing?

Type 1 diabetes is a condition that can lead to serious long-term complications and can have significant psychological and quality of life implications. Its incidence is increasing in all parts of the world, but the reasons for this are incompletely understood. Genetic factors alone cannot explain such a rapid increase in incidence; therefore, environmental factors must be implicated. Lifestyle factors have been classically associated with type 2 diabetes. However, there are data implicating obesity and insulin resistance to type 1 diabetes as well (accelerator hypothesis). Cholesterol has also been shown to be correlated with the incidence of type 1 diabetes; this may be mediated by immunomodulatory effects of cholesterol. There is considerable interest in early life factors, including maternal diet, mode of delivery, infant feeding, childhood diet, microbial exposure (hygiene hypothesis), and use of anti-microbials in early childhood. Distance from the sea has recently been shown to be negatively correlated with the incidence of type 1 diabetes. This may contribute to the increasing incidence of type 1 diabetes since people are increasingly living closer to the sea. Postulated mediating mechanisms include hours of sunshine (and possibly vitamin D levels), mean temperature, dietary habits, and pollution. Ozone, polychlorinated biphenyls, phthalates, trichloroethylene, dioxin, heavy metals, bisphenol, nitrates/nitrites, and mercury are amongst the chemicals which may increase the risk of type 1 diabetes. Another area of research concerns the role of the skin and gut microbiome. The microbiome is affected by many of the factors mentioned above, including the mode of delivery, infant feeding, exposure to microbes, antibiotic use, and dietary habits. Research on the reasons why the incidence of type 1 diabetes is increasing not only sheds light on its pathogenesis but also offers insights into ways we can prevent type 1 diabetes.

The differential role of practical and emotional support in infant feeding experience in the UK.

Social support is a known determinant of breastfeeding behaviour and is generally considered beneficial. However, social support encompasses a myriad of different supportive acts, providing scope for diverse infant feeding outcomes. Given the vulnerability of postpartum mental health, this paper aims to explore both how support prolongs breastfeeding and which forms of support promote the positive experience of all infant feeding. Using survey data collected online from 515 UK mothers with infants aged 0-108 weeks, Cox regression models assessed the relationship between receiving different types of support, support need and breastfeeding duration. Quasi-binomial logistic regression models assessed the relationship between receiving support, infant feeding mode and maternal experience of infant feeding. Rates of negative infant feeding experience indicate the widespread need for support: e.g. 38% of currently, 47% of no longer and 31% of never breastfeeding women found infant feeding stressful. Overall, practical support via infant feeding broadly predicted shorter breastfeeding durations and poorer feeding experience; results in relation to other forms of support were more complex. Our findings indicate different forms of support have different associations with infant feeding experience. They also highlight the wide range of individuals beyond the nuclear family on which postpartum mothers in the UK rely. This article is part of the theme issue 'Multidisciplinary perspectives on social support and maternal-child health'.

Lactobacillus reuteri Colonisation of Extremely Preterm Infants in a Randomised Placebo-Controlled Trial.

Lactobacillus reuteri DSM 17938 supplementation reduces morbidities in very low birth weight infants (<1500 g), while the effect on extremely low birth weight infants (ELBW, <1000 g) is still questioned. In a randomised placebo-controlled trial (ClinicalTrials.gov ID NCT01603368), head growth, but not feeding tolerance or morbidities, improved in L. reuteri-supplemented preterm ELBW infants. Here, we investigate colonisation with the probiotic strain in preterm ELBW infants who received L. reuteri DSM 17938 or a placebo from birth to postmenstrual week (PMW) 36. Quantitative PCR was used on 582 faecal DNA samples collected from 132 ELBW infants at one, two, three, and four weeks, at PMW 36, and at two years of age. Human milk oligosaccharides were measured in 31 milk samples at two weeks postpartum. At least 86% of the ELBW infants in the L. reuteri group were colonised with the probiotic strain during the neonatal period, despite low gestational age, high antibiotic pressure, and independent of infant feeding mode. Higher concentrations of lacto-N-tetraose, sialyl-lacto-N-neotetraose c, and 6′-sialyllactose in mother’s milk weakly correlated with lower L. reuteri abundance. Within the L. reuteri group, higher L. reuteri abundance weakly correlated with a shorter time to reach full enteral feeding. Female sex and L. reuteri colonisation improved head growth from birth to four weeks of age. In conclusion, L. reuteri DSM 17938 supplementation leads to successful colonisation in ELBW infants.

Efficacy of Mobile phone use on adherence to Nevirapine prophylaxis and retention in care among the HIV-exposed infants in prevention of mother to child transmission of HIV: a randomized controlled trial

BackgroundHIV is a major contributor to infant mortality. A significant gap remains between the uptake of infant and maternal antiretroviral regimens and only a minority of HIV-exposed infants receives prophylaxis and safe infant feeding. Losses to follow-up of HIV-exposed infants are associated with shortcomings of facility-based PMTCT models with weak community support of linkages. Use of mobile phones offers an opportunity for improving care and promoting retention assessed by timely attendance of scheduled appointments for the mother-baby pairs and achievement of an HIV-free generation. The objective of this study was to compare self-reported adherence to infant Nevirapine (NVP) prophylaxis and retention in care assessed by timely attendance of scheduled appointments over 10 weeks in HIV exposed infants randomized to 2-weekly mobile phone calls (intervention) versus no phone calls (control).MethodsIn this open label randomized controlled study, one hundred and fifty HIV infected women drawn from 3 health facilities in Western Kenya and their infants were randomly assigned to receive either phone-based reminders on PMTCT messages or standard health care messages (no calls) within 24 h of delivery. Women in the intervention arm continued to receive fortnightly phone calls. At 6- and 10-weeks following randomization we collected data on infant adherence to Nevirapine, mode of infant feeding, early HIV testing and retention in care in both study arms. All analyses were intention to treat.ResultsAt 6 weeks follow-up, 90.7% (n = 68) of participants receiving phone calls reported adherence to infant NVP prophylaxis, compared with 72% (n = 54) of participants in the control group (p = 0.005). Participants in the intervention arm were also significantly more likely to remain in care than participants in the control group [78.7% (n = 59) vs. 58.7% (n = 44), p = 0.009 at 6 weeks and 69.3% (n = 52) vs. 37.3% (n = 28), p < 0.001 at 10 weeks].ConclusionsThese results suggest that phone calls are potentially an important tool to improve adherence to infant NVP prophylaxis and retention in care for HIV-exposed infants.Trial registrationPACTR202007654729602. Registered 6 June 2018 - Retrospectively registered, https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3449

Bottle-feeding, a neglected area of learning and support for nurses working in child health: An exploratory qualitative study.

Breastfeeding is the ideal infant feeding modality; however, the reality is some parents need or choose to use bottles to feed their infants. Parents who bottle-feed have been identified as not receiving adequate levels of bottle-feeding information and advice from health professionals. This study's aim was to explore nurses' knowledge of the components in the bottle-feeding act. Twenty-one nurses working in early parenting residential units participated in three focus groups. Three themes were identified relating to nurses' bottle-feeding knowledge: experience not evidence-based, it is hard to know what to advise, we will support whatever choice they make. The nurses identified a deficit in their knowledge, education and training related to the components of bottle-feeding. The nurses struggled with their interpretation of infant feeding policies and the provision of bottle-feeding information to parents. Nurses working in child and family health were motivated to inform, educate and enable parents to confidently make decisions concerning infant feeding. The healthcare system and the infant feeding policy drivers appear to have a mixed and at times negative impact on nurses' practice. Further research is required across a larger population of nurses.

The relationship between maternal pre-pregnancy body mass index and exclusive breastfeeding initiation: Findings from an Australian obstetric cohort

BackgroundTo assess the type of infant nutrition at initiation of first feed in association with increasing maternal pre-pregnancy Body Mass Index in an Australian obstetric population. MethodsA retrospective cohort study from 2008 to 2013 was undertaken. Body Mass Index was available for 12,347 women categorised into groups according to: underweight (≤18 kg/m2); normal weight (19−24 kg/m2); overweight (25−29 kg/m2); obese class I (30−34 kg/m2); obese class II (35−39/kg2) and obese class III (40+ kg/m2). Type and initiation of infant feeding is routinely recorded in the study hospital’s birthing outcomes system. Six body mass index categories and mode of infant feeding were examined using logistic regression. Confounding factors that were controlled for included smoking status, parity, country of birth and maternal age. ResultsWithin this cohort, 609 (4.93%) women were underweight, 6235 (50.50%) had a normal BMI, 3116 (25.24%) were overweight, 1314 (10.64%) were obese class I, 596 (4.83%) were obese class II and 477 (3.86%) were obese class III. In adjusted models’, as BMI rose, women were significantly less likely to initiate exclusive breastfeeding and more likely to exclusively formula feed. Women with a BMI of 40+ kg/m2 had an AOR of 2.91(CI 1.94−4.25) for initiating exclusive formula at the time of their infant’s first feed. ConclusionsWomen who are overweight or obese are significantly less likely to initiate exclusive breastfeeding and more likely to give exclusive formula at the time of their newborn infants first feed. Effective breastfeeding interventions are required for these high-risk groups in the days leading up to and within the first hours after birth.

Understanding breastfeeding behaviours: a cross-sectional analysis of associated factors in Ireland, the United Kingdom and Australia

BackgroundBreastfeeding is a complex behaviour relying on a combination of individual mother and infant characteristics, health systems, and family, community and professional support. Optimal breastfeeding in high-income countries is particularly low. Despite having similar sociocultural backgrounds, breastfeeding rates between Ireland, the United Kingdom (UK) and Australia vary, thus there is a need to understand whether this is due to individual, sociocultural or policy differences. This research identifies the between-country differences in infant feeding mode and examines if country differences in feeding mode persist once known individual, behavioural and structural factors are considered using socioecological and person-context models.MethodsParticipants were adult women with at least one infant less than 6 months of age, who completed an online survey (n = 2047) that was distributed by social media in June 2016. Within-country differences in infant feeding mode (‘any breastfeeding’ vs. ‘no breastfeeding’) were examined first before hierarchical multivariable logistic regression was used to determine if country differences in feeding mode persisted after adjusting for known factors associated with breastfeeding.ResultsIn this sample, ‘any breastfeeding’ rates were 89, 71 and 72% in Australia, Ireland and the United Kingdom respectively. Within-country differences were evident in Australia, Ireland and the UK. Four factors showed no association with infant feeding mode in Australia while they did in the other countries (maternal age, income, skin-to-skin contact, support from friends and family). Two factors were unique to Australia: the odds of being in the ‘no breastfeeding’ group increased when the baby was delivered via caesarean and when not enough breastfeeding information was available after birth. One determinant was unique to Ireland: the odds of being in the ‘no breastfeeding’ group increased when respondents indicated they were not religious; in the UK this occurred when respondents were living in a town/village. After adjusting for sets of known factors of infant feeding mode based on socioecological and person-context models, country differences remained in hierarchical regressions: the odds of not breastfeeding were higher in both Ireland (AOR 3.3, 95%CI 1.8,6.1) and the United Kingdom (AOR 2.7, 95%CI 1.5, 4.7) compared to Australia.ConclusionsThis study indicates that different levels in the socioecological system are related to infant feeding behaviours. An adequate inter-systems level response would consider the interactions within and between behavioural and structural mechanisms which support breastfeeding behaviour. Optimising infant feeding practices will require an integrated web of interventions that go beyond the individual and focus on addressing factors that will influence families within their communities as they move between systems.

Post-breastfeeding stress response and breastfeeding self-efficacy as modifiable predictors of exclusive breastfeeding at 3\u2009months postpartum: a prospective cohort study

BackgroundThe rate of exclusive breastfeeding at 3 months postpartum is only 50% in Japan. In order to increase this rate, we aimed to examine modifiable factors related to exclusive breastfeeding at 3 months postpartum by focusing on breastfeeding-related and psychosocial variables at 1 month postpartum.MethodsThis prospective cohort study was conducted at a secondary medical care center in Osaka, Japan from February 2017 to October 2018. Demographic variables, infant feeding modality, breastfeeding-related variables, and psychosocial variables were obtained using questionnaires at 1 month postpartum. Daytime salivary cortisol levels before and after breastfeeding at 1 month postpartum were measured as a biological marker for stress responses associated with breastfeeding. Each infant’s feeding modality was re-assessed at 3 months postpartum. Multiple logistic regression analyses were performed to examine factors affecting exclusive breastfeeding at 3 months postpartum.ResultsOf the 104 participants, 61 reported exclusive breastfeeding at 3 months postpartum. The following factors were significantly associated with exclusive breastfeeding at 3 months postpartum: multiparity (adjusted odds ratio, 95% confidence interval: 11.13, 2.08–59.59), having a university degree (5.25, 1.04–26.53), no plan to return to work by 6 months postpartum (0.02, 0.00–0.46), and exclusive breastfeeding (42.84, 6.05–303.52), lower cortisol level after breastfeeding (0.00, 0.00–0.02), and higher breastfeeding self-efficacy scale score (1.07, 1.00–1.14) at 1 month postpartum. In parity-specific analyses, exclusive breastfeeding (25.33, 4.75–134.98) and lower cortisol level after breastfeeding (0.00, 0.00–0.21) at 1 month postpartum in primiparous women, and lower cortisol level after breastfeeding (0.00, 0.00–0.94), higher breastfeeding self-efficacy score (1.18, 1.05–1.32), and absence of breast complications (0.09, 0.01–0.82) at 1 month postpartum in multiparous women were associated with exclusive breastfeeding at 3 months postpartum.ConclusionsStress levels after breastfeeding, breastfeeding self-efficacy, and the presence of breast complications could be modifiable factors associated with subsequent exclusive breastfeeding. Further research is needed to examine whether approaches to reducing breastfeeding-related stress, improving breastfeeding self-efficacy, and preventing breast complications during lactation are effective to increase exclusive breastfeeding practices.

Expressed breast milk feeding practices in Hong Kong Chinese women: A descriptive study

IntroductionThere is an increasing prevalence of breast milk expression and expressed breast milk feeding in healthy full-term infants. The purpose of this study was to provide up-to-date evidence on the practice of expressed breast milk feeding and to identify factors associated with expressed breast milk feeding in Hong Kong Chinese mothers of healthy full-term infants. MethodWe used a prospective cohort study design to recruit 821 mothers who gave birth to healthy full-term infants in two public hospitals in Hong Kong. Participants completed self-administered baseline questionnaires during their postpartum stay and were followed-up by a series of telephone calls over a 6 months period or until they stopped breastfeeding, whichever came first. The proportion, mode, and type of infant feeding (direct breastfeeding, expressed breast milk feeding and infant formula feeding) were assessed at each telephone follow-up. ResultsIn our sample, 14.6%, 20.2% and 15% of the participants fed expressed breast milk only to their infants at 1.5, 3 and 6 months respectively. Less than one-half were giving only direct breastfeeding only at 1.5 and 3 months. Within the first six months postpartum, 84.6% of the participants had given expressed breast milk. More than 80% of participants obtained a breast pump before giving birth, with the majority obtaining electric pumps. The most common reason for expressing breast milk within the first 1.5 months postpartum was experiencing breastfeeding difficulties (35%). Returning to employment was the strongest predictor of expressed breast milk feeding at three months postpartum (adjusted odds ratio [aOR]=8.71, 95% Confidence interval [CI]= 5.12–14.8). ConclusionA high proportion of Hong Kong Chinese mothers of healthy, full-term infants pump and feed expressed breast milk at some point during the first 6 months postpartum. Participants purchase or obtain breast pumps before giving birth, often in anticipation of breastfeeding difficulties and returning to work.

Paternal Roles in Breastfeeding in Jakarta, Indonesia: A Mixed-method Approach

Abstract We explored paternal roles in timely breastfeeding initiation and exclusive breastfeeding practices in Jakarta using a mixed-methods approach in sequence of focus group discussions (FGDs – phase 1) and a quantitative survey (phase 2). The study population was parents with infants aged below 6 months. Data on paternal roles, maternal attributes, and breastfeeding practices were collected from 43 purposively selected parents in phase 1 and 536 couples in phase 2. FGDs provided insights to finalize the questionnaire for the survey. Nine paternal roles were identified: 1-accompanying the mother during antenatal and postnatal visits, 2-suggesting places for health checkups and delivery, 3-seeking information about child nutrition, 4-accompanying the mother during delivery, 5-facilitating psychological support of the mother, 6-childcare involvement, 7-engagement in childcare discussions, 8-involvement in decisions about infant feeding mode, and 9-enthusiasm for fatherhood. Roles 3 (aOR=1.65; 95%CI=1.07 to 2.54) and 9 (1.59; 1.04-2.44) were positively associated with timely initiation of breastfeeding. Role 8 was positively associated with exclusive breastfeeding (1.69; 1.10-2.60), but roles 2 (0.49; 0.32-0.76) and 5 (0.97; 0.41-0.64) were negatively associated with exclusive breastfeeding. Fathers played roles in breastfeeding practices under study. Fathers need a tailored breastfeeding promotion to stimulate necessary support for breastfeeding mothers. Keywords: initiation of breastfeeding, exclusive breastfeeding, fathers, mixed-methods approach, Indonesia

The risk of infectious pathogens in breast-feeding, donated human milk and breast milk substitutes.

This review collates the published reports that focus on microbial and viral illnesses that can be transmitted by breast milk, donor milk and powdered infant formula (PIF). In this context, we attempt to define a risk framework encompassing those hazards, exposure scenarios, vulnerability and protective factors. A literature search was performed for reported cases of morbidity and mortality associated with different infant feeding modes. Exclusive breast-feeding is the recommended for infant feeding under 6 months, or failing that, provision of donated human milk. However, the use of PIF remains high despite its intrinsic and extrinsic risk of microbial contamination, as well as the potential for adverse physiological effects, including infant gut dysbiosis. Viable pathogen transmission via breast-feeding or donor milk (pasteurised and unpasteurised) is rare. However, transmission of HIV and human T-cell lymphotropic virus-1 is a concern for breast-feeding mothers, particularly for mothers undertaking a mixed feeding mode (PIF and breast-feeding). In PIF, intrinsic and extrinsic microbial contamination, such as Cronobacter and Salmonella, remain significant identifiable causes of infant morbidity and mortality. Disease transmission through breast-feeding or donor human milk is rare, most likely owing to its complex intrinsically protective composition of human milk and protection of the infant gut lining. Contamination of PIF and the morbidity associated with this is likely underappreciated in terms of community risk. A better system of safe donor milk sharing that also establishes security of supply for non-hospitalised healthy infants in need of breast milk would reduce the reliance on PIF.

Estimated Causal Effects of Complementary Feeding Behaviors on Diet Quality in Early Childhood Using Birth Cohort Data

Abstract Objectives We aimed to examine effects of 3 complementary feeding behaviors on later diet quality using a causal inference framework. Methods Using data from 1041 mother-child pairs from the Boston, MA-area Project Viva cohort, we estimated effects on the mean Youth Healthy Eating Index (YHEI) score, a measure of diet quality in early childhood, of hypothetical interventions that expose (vs. do not expose) to the following: 1) introduce sweets and fruit juice at ≥12 m and provide no daily fruit juice at age ∼1 y; 2) introduce varied, non-sweet flavors (at least 2/3 of fish, eggs and peanut butter) at &amp;lt;12 m; and 3) continue offering foods initially refused by the child. Mothers reported complementary feeding behaviors (exposures) at 1y and completed food frequency questionnaires for children in early childhood (median age 3.2 y). We estimated average treatment effects (ATEs) using inverse probability weighted linear regression analysis with stabilized weights to adjust for both confounding and selection bias due to censored outcomes. For each effect, we adjusted for child race/ethnicity, maternal socio-demographics, BMI, and diet quality, and the other 2 exposures, and examined effect modification by child sex and infant feeding mode (breastfed at 6 m [BF group] vs. not [FF group]). Results Of 1041 pairs, 12% delayed introducing sweets/fruit juice and provided no daily fruit juice at 1y, 68% introduced fish, eggs and peanut butter before 12 m, and 93% continued to offer refused foods. We estimated that mean YHEI score was higher under “delay sweets and fruit juice” (1.8 points, 95% CI: −1.0, 5.5), particularly among the BF group (ATE 5.1 points, 95% CI: 0.0, 8.7) and females (ATE 4.4 points, 95% CI: −2.0, 9.0). ATEs for the “early flavor variety” exposure were 1.7 points (95% CI: 0.2, 3.0) and similar among males and females but stronger (2.6 points, 95% CI: 0.4, 4.8) among the FF group. Mean YHEI score was also higher (2.6 points, 95% CI: −1.1, 6.5) under the “continue offering refused foods” exposure, particularly among females (ATE 5.7 points, 95% CI: 1.2, 9.6). Conclusions Delayed introduction of sweets and fruit juice, early introduction of varied, non-sweet flavors, and continued offering of initially refused foods may result in better diet quality in early childhood. Effects may differ by child sex and breastfeeding status. Funding Sources US NIH.

Developmental assessments during the first 5 years of life in infants fed breast milk, cow's milk formula, or soy formula.

ObjectiveTo investigate the effects of infant feeding mode on childhood cognition and language as the differential effects of infant feeding on development remain understudied.MethodsBreastfed [BF, 174], cow's milk‐based formula‐fed [MF, 169], or soy protein‐based formula‐fed [SF, 161] children were longitudinally tested from age 3 to 60 months for neurodevelopment. Data were analyzed using mixed models while adjusting for multiple covariates. Sex differences were also assessed.ResultsStandard scores were within established norms for all groups. There were no differences in mental development to age 24 months, yet BF children had significantly higher motor development scores at age 3 months than SF children (99.1 versus. 97.2). BF children had significantly higher composite intelligence scores at 48 months than MF and SF children (113.4 versus. 109.6 and 108.4, respectively) and higher verbal intelligence scores than SF children at 48 (105.6 versus. 100.7) and 60 months (109.8 versus. 105.9). Greater total language scores at ages 36 and 48 months were found in BF children compared with children fed MF or SF (p < .001), with differences between sexes for auditory comprehension. Higher total language scores at age 60 months were found between BF and SF (105.0 versus. 100.1).ConclusionBreastfeeding was associated with small, statistically significant, differences between children ages 3 and 5 years in verbal intelligence, expressive communication, and auditory comprehension with the latter having potential sexual dimorphic effects. Yet, these differences remain small and may not be of clinical relevance. Overall, MF and SF did not significantly differ.

Exclusive breastfeeding in first-time mothers in rural Kenya: a longitudinal observational study of feeding patterns in the first six months of life

BackgroundExclusive breastfeeding up to 6 months of age is recommended by the World Health Organization as the optimal mode of infant feeding, providing adequate nutrition for the baby and protection against infectious diseases. Breastfeeding can be adversely affected by individual, cultural and socio-economic factors. The study aimed to explore barriers of exclusive breastfeeding in the first 6 months of life among first-time mothers in rural Kenya.MethodsAn observational longitudinal design aimed to provide rich data on breastfeeding behaviour. Twenty pregnant first-time mothers were recruited through antenatal clinics and snowballing. Mothers were visited nine times at home from late pregnancy, at 1 week and 2 weeks post-delivery, then monthly until the baby was aged 6 months. Visits were conducted between November 2016 and April 2018. At the first visit, participants were asked about breastfeeding intentions and infant feeding education received. At each postnatal visit, direct observation of breastfeeding, a recorded semi-structured interview on feeding, mother’s and baby’s health was performed. Interviews were transcribed, checked, content was grouped into categories and analyzed using a qualitative descriptive approach.ResultsMost participants were adolescent (75%) and unmarried (65%). All 20 mothers intended to and did breastfeed, however additional fluids and semi-solids were commonly given. Only two mothers exclusively breastfed from birth up to 6 months of age. Prelacteal feeds, home remedies and traditional medicine were given by over a third of mothers in the first week of life. Concern over babies’ bowel habits and persistent crying perceived as abdominal colic led to several mothers receiving advice to give gripe water and traditional remedies. Early introduction of maize porridge from 3 months of age because of perceived hunger of the child was recommended by other family members. Breastfeeding observation showed persistent problems with positioning and attachment of infants.ConclusionsExclusive breastfeeding from birth to 6 months was uncommon. Prioritization of capacity to detect mothers with breastfeeding problems and provide breastfeeding education and support is necessary, particularly during the antenatal and early postnatal period. It is important to engage with other women resident in the household who may offer conflicting feeding advice.

Associations between maternal BMI, breastfeeding practices and infant anthropometric status in Colombia; secondary analysis of ENSIN 2010

BackgroundMaternal malnutrition and infant feeding mode impact short and long term infant and child morbidity and mortality. The period of lactation may provide an opportunity to modulate the risk of disease later in life. Our aim was to estimate the effect of maternal body mass index (BMI) and infant feeding mode, particularly breastfeeding practices, on the anthropometric status of children under 2 years in Colombia.MethodsA secondary analysis was performed using the data from ENSIN 2010. Term infants under 2y, singleton, with a mother older than 18y, were included in the analysis. Outcomes were wasting (WLZ < -2SD), overweight (WLZ > +2SD) and stunting (LAZ < -2SD). Predictors were infant feeding (exclusive and predominant BF constructed from 24-h recall, age at introduction of liquids, semisolids and solids) and maternal BMI. Socioeconomic variables, maternal education and age, conditions during pregnancy and birth weight were analyzed as covariates.ResultsMothers of overweight infants had higher BMI (Mean dif = 1.47 kg/m2; 95% CI = 2.1, 0.8) than those with normal weight infants. Stunting and wasting were not predicted by maternal anthropometry or infant feeding mode. Fewer maternal years of education were associated with wasting (OR = 0.90; 95% CI = 0.86, 0.97; p = 0.003) and stunting (OR = 0.92; 95% CI = 0.89, 0.94; p < 0.0001), while more maternal years of education were associated with overweight (OR = 1.06; 95% CI = 1.02, 1.01; p = 0.001); higher birth weight was associated with overweight (OR = 1.001; 95% CI = 1.00, 1.001; p < 0.0001) and lower birth was associated with stunting (OR = 0.99; 95% CI = 0.89; p < 0.0001) in the final regression model.ConclusionsMaternal BMI is a modifiable target for public health policy to promote healthy infant growth. Infant nutritional status is affected by direct and indirect factors that need to be addressed in further studies.

Bottle-feeding an infant feeding modality: An integrative literature review.

Bottle‐feeding is an infant feeding modality that has been in existence since ancient times, and currently, a significant number of infants are being fed via a bottle with either breastmilk or formula. Although research on bottle‐feeding has continued, it exists in fragmented, often small studies that focus on singular aspects of feeding an infant using a bottle, with limited information on the bottle‐feeding act. Systems theory was the approach used to define the act of bottle‐feeding and identify the parts within this act. Health databases were searched using MeSH terms. A summary of the studies are included. The findings of this review revealed that healthy term bottle‐feeding infants use similar tongue and jaw movements, can create suction and sequentially use teat compression to obtain milk, with minimal differences in oxygen saturation and SSB patterns, when compared with breastfeeding infants. Bottle and teat characteristics were revealed to affect infant feeding and milk intake. An infant's milk intake during feeding was shown to have a strong association with the interaction between the infant and parent/caregiver. With the issue of who controls the feed, mother or infant, likely to affect an infant's ability to self‐regulate their milk intake. Redefining bottle‐feeding as a holistic system identifies the interrelationship of the various parts which will improve the understanding of the reciprocal nature of infant feeding. To optimize bottle‐feeding outcomes, further research is required on parents' and health professionals' knowledge and understanding of the parts within the act of bottle‐feeding.

Analysis of antenatal and postnatal determinants which promote postpartum weight loss in obese women - An analysis from the UPBEAT trial

AbstractIn the UK 21% of pregnant women are categorised as obese(1). Women who enter pregnancy with a high body mass index (BMI) are at greater risk of gestational weight gain (GWG) above that recommended by the Institute of Medicine (IOM) and are less likely to return to their pre-pregnancy weight compared to women with a healthy BMI(2). Pregnancy can therefore alter a woman's weight gain trajectory across the life course, through retention of gestational weight gained. Given the increase in prevalence of obesity among women of reproductive age, the aim of this study was to identify antenatal and postnatal modifiable determinants associated with successful postpartum weight loss in women who participated in UPBEAT; a multi-centre randomised controlled trial comparing a lifestyle intervention of diet and physical activity to standard care during pregnancy.710 women completed the 6-month postpartum follow-up visit, 464 (65%) of which provided complete data for the analysis. Using regression analysis, we examined the relationship between postpartum weight retention (PPWR; calculated by subtracting pre-pregnancy weight from six-month postpartum weight) and modifiable determinants including: reported glycaemic index and smoking status at baseline (15–18 weeks’ gestation), GWG within the IOM recommendations, self-reported postpartum physical activity (categorised as low, moderate or high) and mode of infant feeding (breastfed, formula or mixed). Women were excluded if they gave birth &lt; 37 weeks gestation or they were pregnant at the 6-month visit. Results were adjusted for age, BMI, ethnicity, socio-economic status, parity and randomisation arm.In this cohort of obese women 52% were at or below their pre-pregnancy weight by 6 months postpartum. Overall, there was a reduction in PPWR of -0.23 ± 6.7 kg [-23.5 to 23.0 kg]. In an adjusted multiple regression model, women who breastfed for ≥ 4months, had moderate or high levels of physical activity and appropriate GWG, were more likely to be at or below their pre-pregnancy weight by 6-months postpartum (all p &lt; 0.02). In a mutually-adjusted multivariate model, for each additional factor women lost a further -1.5 kg (95%CI -2.3 to -0.68; p &lt; 0.001) compared to their pre-pregnancy weight.This study has shown that there is an incremental association with postpartum weight loss and the identified modifiable determinants. These findings support initiatives which target any or all these factors during the antenatal and postnatal periods to help support women with returning to their pre-pregnancy weight.