Shared e-scooters refer to a micro-mobility service that enables the short rentals of e-scooters. The rapid growth of e-scooter sharing has sparked a heated discussion about its role in the urban mobility sector. This article presents a systematic review of the current knowledge on its uses and users, health and environmental impacts, and policy issues. The analysis is based on academic literature, identified with Google Scholar by using keywords and publication years from 2017, and relevant gray literature. Firstly, we highlight that the profiles of e-scooter renters seem to highly match the characteristics of other micro-mobility services users. Secondly, e-scooters are often associated with a high perception of risk from the public and an increasing occurrence of related road accidents. Thirdly, even if promoted as a green mobility option, the true environmental impact of shared e-scooters has only started to be investigated. Early studies point out negative impacts around their production, usage, and maintenance. Fourthly, the integration of shared e-scooters into the existing transport systems requires policy changes, both at the local and national level, including traffic regulations, safety rules, and physical infrastructure. Finally, this paper reveals the ambiguity of the term “e-scooter” and stresses the need for more research, as the future of cities is tied to the development of low-car lifestyles.