Mixed-ligand Coordination Polymers Research Articles

RETRACTED ARTICLE: METAL ION-DIRECTED SYNTHESIS OF TWO MIXED-LIGAND COORDINATION POLYMERS: PROTECTIVE ACTIVITY ON THE ACUTE KIDNEY INJURY BY REDUCING THE NAGL CONTENT IN URINE

In the current study, two new mixed-ligand coordination polymers with the chemical formulae of {[Cu(oba)(4-bpdb)]·CH3OH}n (1) and {[Co3(oba)3(4-bpdb)(DMF)2]·4H2O}n (2) (H2oba = 4,4′-oxybis-benzoate, 4-bpdb = 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene) are synthesized under solvothermal conditions. Both structures are analyzed by single crystal X-ray diffraction along with the elemental analysis. Their prevention activity on the acute kidney injury in patients with acute cerebral hemorrhage is evaluated and the protentional mechanism is revealed. Firstly, the Nagl content in urine is measured. Secondly, the inflammatory response in glomerular epithelial cells is detected by real-time RT-PCR.

Metal ion-directed assembly of two mixed-ligand coordination polymers: treatment effect on acute kidney injury by reducing urine Nagl content

In the current study, two new transition metal-organic coordination polymers (CPs) with the chemical formula of [Cu(L)(OBA)(H2O)]n (1) and [Co(L)(OBA)]n (2) (H2OBA = 4,4(L)(OBA)]dy, two new traL = 1,4-bis(benzimidazol-1-yl)-2-butylene) were synthesized under solvothermal reaction conditions by using different metal centers as the nodes, which results in the structural differences in the as-prepared products although the same organic ligands are used. For the acute kidney injury treatment, their treatment activity on the acute kidney injury was evaluated and the related mechanism was explored at the same time. First of all, the ELISA detection kit was performed to determine the content of the neutrophil gelatinase-associated lipocalin (Nagl) in the urine after compounds 1 and 2 treatment. Besides, the real-time RT-PCR was conducted and the relative expression of the jak and stat in the glomerular epithelial cells was measured as well.

2D/3D coordination polymers: treatment effect on the ulcerative colitis by reducing the inflammatory response

Two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L1)(bdc)](H2O)}n (1, L1 = 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene, H2bdc = terephthalic acid) and {[Co(L2)(bdc)](H2O)}n (2, L2 = 1,3-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene) have been successfully prepared by the solvothermal treatment of H2bdc and different N-donor co-ligands with Co(II) salt. In biological functional study, the treatment effect of compounds 1 and 2 on the ulcerative colitis (UC) was evaluated. Firstly, the ELISA assay was performed to reveal the changes of the inflammatory cytokines caused by compounds. Besides, the model of mice was established and the mice' body weight was measured and recorded at the 7th and 14th day after compounds treatment.

RETRACTED ARTICLE: Two mixed-ligand coordination polymers: structural diversity and anticancer activity on cervical carcinoma

We, the Editors and Publisher of the journal Inorganic and Nano-Metal Chemistry, have retracted the following article: Su-Fen Li, Si-Si Tang, Shuang-Yan Weng & Min Xia (2021) Two mixed-ligand coordination polymers: structural diversity and anticancer activity on cervical carcinoma, Inorganic and Nano-Metal Chemistry. 2021; VOL. 51, NO. 10, 1361–1368. DOI: 10.1080/24701556.2020.1835975 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors have been unable to address the concerns raised and have not been able to provide sufficient supporting information. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. The authors have agreed to retract the article. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.

A new mixed-ligand Co(II) coordination polymer: treatment activity on ulcerative colitis by inhibiting the JAK2/STAT3 signaling pathway in the colonic epithelial cells

In the current study, a novel mixed-ligand coordination polymer, {[Co(L)(dpe)]·(ClO4)} (1) (H2LCl = 3-carboxy-1-(3-carboxybenzyl)pyridin-1-ium, dpe = (E)-1,2-di(pyridin-4-yl)ethene), was synthesized under hydrothermal conditions by a zwitterionic organic ligand and fully characterized by the single crystal X-ray diffraction, powder X-ray diffraction, elemental analysis along with the FT-IR. Furthermore, the treatment activity of the compound on the ulcerative colitis was evaluated and the related mechanism was explored. First, the level of the tumor necrosis factor (TNF)-α and superoxide dismutase (SOD) released by the colon tissue into the plasma was measured with enzyme-linked immunosorbent assay (ELISA) detection kit. In addition to this, the activation level of the JAK2/STAT3 signaling pathway in the colonic epithelial cells was also determined with western blot. With the help of molecular docking simulation, the potential interacting gestures between the complex and the protein have been revealed.

RETRACTED ARTICLE: TWO NEW Co(II)-BASED COORDINATION POLYMERS:STRUCTURAL CHARACTERIZATION AND PROTECTIVE EFFECT ON PARKINSON DISEASE BY IMPROVING THE CONTENT OF DOPAMINE IN THE SUBSTANTIA NIGRA

Two new mixed-ligand coordination polymers with the chemical formulae {[Co(5-amipa)(bpe)]DMF}n (1, H2amipa = 5-aminoisophthalic acid, bpe = 1,2-bis(4-pyridyl)ethylene, DMF = dimethylformamide) and {[Co(5-amipa)(bpe)](DMA)}n (2, DMA = dimethylacetamide) are successfully synthesized by the solvothermal reaction of 5-aminoisophthalic acid and the N-donor 1,2-bis((4-pyridyl)ethylene) co-ligand with Co(II) salt in different solvent systems. All compounds are adequately characterized, and their structures are verified by single crystal X-ray diffraction along with the elemental analysis. Furthermore, the protective effect of compounds 1 and 2 on Parkinson disease is evaluated in the biological function section. Firstly, the ELISA detection is performed to estimate the dopamine content in the substantia nigra after treatment with the compounds. Then the open field test is finished to reflect the treatment ability of the compounds on the cognitive ability of mice.

RETRACTED ARTICLE: TWO MIXED-LIGAND Cu(II)-BASED COORDINATION POLYMERS: CRYSTAL STRUCTURES AND TREATMENT ACTIVITY ON CHILD ACUTE PANCREATITIS WITH PERITONITIS BY INHIBITING THE BACTERIAL SURVIVAL

Two mixed-ligand coordination polymers with the chemical formulae {[Cu3(Hdpc)2(tib)2(H2O)2]·2H2O)}n (1, H3dpc = 2,6-di(4-carboxylphenyl)pyridine-4-carboxylic acid, tib = 1,3,5-tris(1-imidazolyl)benzene)) and [Cu(trans-chda)2(bimb)2·2H2O]n (2, H2chda = 1,4-cyclohexane(dicarboxylic)acid, bimb = 1,4-bis((1H-1,2,4-triazol-1-yl)methyl)benzene) are successfully prepared by the reaction of Cu(NO3)2·3H2O with different O-donor carboxylic acid and N-donor co-ligands under the solvothermal conditions. Furthermore, the treatment effect of the two compounds on the acute pancreatitis is evaluated in the biological experiment. Firstly, RT-PCR is performed to measure the relative expression level of the key genes of E. coli. Moreover, the inflammatory levels of the patients are evaluated by the ELISA detection of inflammatory cytokines, IL-1β, and TNF-α.

RETRACTED ARTICLE: STRUCTURAL INSIGHTS AND ANTI-COLON CANCER ACTIVITY OF TWO Zn(II)-BASED COORDINATION POLYMERS BASED ON CARBOXYLATE AND IMIDAZOLE CO-LIGANDS

Two new mixed-ligand coordination polymers [Zn(bdc)(bib)]n (1, H2bdc = 1,3-dicarboxybenzene, bib = 1,3-bis(imidazol-1-yl)benzene) and [Zn(NH2-bdc)(bib)]n (2, NH2–H2bdc = 2-amino-1,4-dicarboxybenzene) are successfully prepared by the reaction of zinc nitrate, N-containing and dicarboxylate ligands under the same hydrothermal conditions. The anti-viability of compounds 1 and 2 is assessed with CCK-8 against SW480 colon cancer cells. To further explore the underlying mechanism of compounds, the cell apoptosis and ROS detection are performed in this experiment.

RETRACTED: Two transition metal coordination polymers: Photocatalytic properties and treatment effect on lipopolysaccharide (LPS) induced kidney injury by regulating pink 1 gene expression and reducing inflammatory response

Abstract Two novel mixed ligand coordination polymers (CPs) {[Co(bdc)(bidp)]·H2O}n (1, bidp = 1,3-bis(5,6-dimethylbenzimidazol-1-yl)propane, H2bdc = 1,4- terephthalic acid) and {[Cd(bdc)(bibh)1.5]·H2O}n (2, bibh = 1,6-bis(benzimidazol-1-yl)hexane) and were prepared and then characterized via powder X-ray diffraction (PXRD) and IR spectra, the analysis of element and the analysis of single crystal X-ray diffraction. In addition, these two complexes have good photocatalytic activities for the degradation of methyl orange (MO) and methylene blue (MB) under the irradiation of ultraviolet light. In the study of biological functions, the protective effect of compounds 1 and 2 were assessed, and their detail mechanisms were discussed. First of all, the relative expression level of the pink 1 gene was determined by reverse transcription-polymerase chain reaction (RT-PCR). After that, the IL-1β and TNF-α content was detected by the enzyme linked immunosorbent assay (ELISA) detection kit.

Two mixed-ligand coordination polymers based on 2,5-thiophenedicarboxylic acid and flexible N-donor ligands: the protective effect on periodontitis via reducing the release of IL-1β and TNF-α

Abstract Two novel mixed-ligand coordination polymers, {[Co(tdc)(btrp)]·0.67DMF} n (1) and {[Zn2(bimb)2(tdc)2]·2H2O} n (2) involving 2,5-thiophenedicarboxylate (H2tdc), and bitopic flexible N-donor ligands, 1,3-bis(1,2,4-triazol-1-yl)propane (btrp) and 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene (bimb), have been synthesized by the hydrothermal method and characterized via IR, elemental analysis, thermal analysis, and powder X-ray diffraction. The biological functional studies were performed; the treatment activity of the compounds on periodontitis and the specific mechanism was explored. First, the real-time RT-PCR was carried out to determine the inflammatory genes nf-κb and p53 relative expression in periodontal mucosal cells after treating with compounds 1 and 2. Then, the level of the inflammatory cytokine in the gingival crevicular fluid after treating with compounds was also determined by the ELISA detection kit.

RETRACTED ARTICLE: A new mixed-ligand coordination polymer: crystal structure and protective effect on viral myocarditis via regulating inflammatory response in vivo

We, the Editors and Publisher of the journal of Inorganic and Nano-Metal Chemistry have retracted the following article: Lei Wang, Yang Liu, Jiabing Zhang & Yunfeng Xia. A new mixed-ligand coordination polymer: crystal structure and protective effect on viral myocarditis via regulating inflammatory response in vivo, Inorganic and Nano-Metal Chemistry, 2020, VOL. 50, NO. 12, 1234–1238. DOI: 10.1080/24701556.2020.1745834 Since publication, significant concerns have been raised about the integrity of the data and reported results in the article. When approached for an explanation, the authors did not provide their original data or any necessary supporting information. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.

Three mixed ligand coordination polymers: Syntheses, characterization and detailed study of the structural transformations

Post synthetic modification of coordination polymers have been extensively studied through years, to obtain several marvelous functional materials. Apart from the usual metal or ligand exchange, irreversible structural transformation strategy may also be a useful approach to perform post synthetic modification in coordination polymers for creating functional materials. Considering this approach, three coordination polymer of Zn(II) and Co(II) namely, {[Zn(beb)(dmglut)]}n (1), {Co2(beb)2(hipt)2(H2O)1.5(MeOH)}]n (2) and {[Zn2(beb)2(fum)2]}n (3) (Whereas beb = 1-(2-(1H-benzoimidazol-1-yl)ethyl)-1H-benzoimidazole, dmglut = 3,3′-dimethylglutarate, hipt = 5-hydroxyisophthalate and fum = fumarate) have been synthesized from flexible beb ligand and three different dicarboxylates. Compound 1 and 2 are with a two dimensional structure which are adjoined by weak forces to form a supramolecular three dimensional architecture. Compound 3 has a three dimensional structure with unidirectional channels. Compound 2 and 3 have undergone irreversible structural transformation. These transformations are thoroughly monitored by PXRD analysis, UV–vis spectroscopy, and IR spectroscopy. Solid state emission spectral analyses for two Zn(II) CPs and gas sorption analyses for all the compounds has been also performed.

RETRACTED ARTICLE: Two mixed-ligand coordination polymers: Structural insights and treatment effect on atherosclerosis by regulating the miRNA-9 mediated NF-κB signaling pathway

We, the Editors and Publisher of the journal Inorganic and Nano-Metal Chemistry, have retracted the following article: Qiu-Feng Jiang, Yu-Tao Ao, Zhi-Fang Zhang, Wen Yue & Dan-Ni Fu. Two mixed-ligand coordination polymers: Structural insights and treatment effect on atherosclerosis by regulating the miRNA-9 mediated NF-κB signalling pathway, Inorganic and Nano-Metal Chemistry. 2020; VOL. 50, NO. 11, 1123–1129. DOI: 10.1080/24701556.2020.1735429 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors have been unable to address the concerns raised and have not been able to provide sufficient supporting information. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. The authors have agreed to retract the article. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.

Two new mixed-ligand coordination polymers: structural characterization and treatment effect on acute adnexitis via inhibiting fitZ gene expression in Staphylococcus aureus

Two new mixed-ligand coordination polymers with the chemical formulae of {[Zn3(nbta)2(bpfp)2(H2O)2](H2O)2}n (1, H3nbta = 5-nitro-1,2,3-benzenetricarboxylic acid, bpfp = bis(4-pyridylformyl)piperazine) and {[Cd3(nbta)1.5(bib)2(H2O)](H2O)}n (2, bib= 4,4’-bis((1H-imidazol-1-yl)methyl)−1,1’-biphenyl) have been successfully synthesized by the solvothermal reaction of 5-nitro-1,2,3-benzenetricarboxylic acid, and different N-donor co-ligand. All compounds were adequately characterized, and their structures were verified by single-crystal X-ray diffraction along with the elemental analysis. Furthermore, the treatment effect of compounds 1 and 2 on the acute adnexitis was evaluated in the biological study. Firstly, the RT-PCR was performed to detect the inhibitory effect of the compounds on the survival gene in the Staphylococcus aureus-fitZ. Then, the ELISA was conducted to measure the release level of the inflammatory cytokines.

RETRACTED ARTICLE: Two new mixed-ligand coordination polymers based on the 5-nitro-1,2,3-benzenetricarboxylic acid and different N-donor ligands: crystal structures and anti-leukemia activity

This article has been retracted. Please see Retraction (http://dx.doi.org/10.1080/24701556.2023.2212222).

Copper 3,4-pyridinedicarboxylate mixed ligand coordination polymers with diverse topologies and aqueous Congo Red degradation catalytic properties

Hydrothermal reaction of copper nitrate, 3,4-pyridinedicarboxylic acid (34pdcH2), and a variety of ditopic dipyridyl ligands afforded six new coordination polymer solids with diverse 2D and 3D topologies as characterized via single-crystal X-ray diffraction. {[Cu(34pdc)(dpa)]·H2O}n (1, dpa = 4,4′-dipyridylamine) reveals a 3,5-connected layered net with a (426)(42678) topology. [Cu(34pdc)(3pina)]n (2, 3pina = 3-pyridylisonicotinamide) manifests a 2-fold interpenetrated 3,5-connected 3D net with (426)(426583) topology. [Cu2(34pdc)2(bbn)(H2O)2]·7H2O}n (3, bbn = bis(butane-1,4-diyl)nicotinamide) shows a 3D trinodal network with {(63)2(6.102)(64102)} topology, with looped pairs of bbn ligands acting as single connectors. [Cu4(34pdc)4(bbin)(H2O)4]·8H2O}n (4, bbin = bis(butane-1,4-diyl)isonicotinamide) displays a quite complicated 3D multinodal network with {(63)2(628)(6282102)(668310)} topology. [Cu2(34pdc)2(pebn)(H2O)]·8H2O}n (5, pebn = bis(pentane-1,5-diyl)nicotinamide) shows a 3,4,4-connected 2D network with {(63)2(6472)(6.74.11)} topology, along with entrapped chair-centered 14-water molecule clusters. [Cu4(34pdc)4(hbn)(H2O)4]·3H2O}n (6, hbn = bis(hexane-1,6-diyl)nicotinamide) showed the same {(63)2(6.102)(64102)} topology as 3, but with single dipyridylamide ligands instead of looped pairs. Thermal decomposition of these six new materials are also probed, along with their catalytic behavior for the aqueous degradation of Congo Red dye in the presence of ultraviolet radiation and hydrogen peroxide.

Two Mixed-ligand Coordination Polymers: Crystal Structures and Protective Effect on Ischemic Stroke by Increasing glp1r Expression.

In this study, two new mixed-ligand coordination polymers {[Co(bbi)(tdc)]·5H2O}n (1, bbi = 1,4-bis(imidazolyl)butane) and {[Cu2(bimb)(H2O)(μ3-tdc)2(DMF)2]·H2O}n (2, bimb = 4-bis(1H-imidazol-1-yl-methyl)benzene) were synthesized under the solvothermal conditions via reaction of 2,5-thiophenedicarboxylic acid (H2tdc) with the corresponding metal salts in the existence of different flexible bis-imidazole ligands (bbi for 1 and bimb for 2). The as-prepared two structures were detected via the single crystal X-ray diffraction (SXRD) and then characterized via the analysis of element, powder X-ray diffraction (PXRD), thermogravimetric analysis (TGA) as well as infrared (IR) spectroscopy. Furthermore, the protective activity of the compound on the mice with ischemic stroke was evaluated. Firstly, the real time reverse transcription-polymerase chain raction (RT-PCR) was carried out to determine the effect of compounds 1 and 2 against the relative expression level of the glucagon-like peptide 1 receptors (glp1r) on the cerebrovascular endothelial cells. Next, the Morris Water Maze Experiment was also used to detect the improvement function of compounds 1 and 2 on the nice mice cognitive function.

RETRACTED ARTICLE: Structural diversity and anti-lung cancer activity evaluation of two Co(II) and Cu(II) containing mixed-ligand coordination polymers

We, the Editors and Publisher of the journal Inorganic and Nano-Metal Chemistry, have retracted the following article: Di Li, Li-Fei Li, Zhi-Fang Zhang, Fan Lin, Lei Pan & Yang Liu. Structural diversity and anti-lung cancer activity evaluation of two Co(II) and Cu(II) containing mixed-ligand coordination polymers, Inorganic and Nano-Metal Chemistry. 2020, 50:4, 229–237, DOI: 10.1080/24701556.2019.1706568 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors have been unable to address the concerns raised and have not been able to provide sufficient supporting information. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. The authors have agreed to retract the article. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.

Metal ion-directed synthesis of two mixed-ligand coordination polymers: protective activity on the acute kidney injury by reducing the Nagl content in urine

In the current study, two new mixed-ligand coordination polymers with the chemical formulae of {[Cu(oba)(4-bpdb)]·CH3OH}n (1) and {[Co3(oba)3(4-bpdb)(DMF)2]·4H2O}n (2) (H2oba = 4,4'-oxybis-benzoate, 4-bpdb = 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene) are synthesized under solvothermal conditions. Both structures are analyzed by single crystal X-ray diffraction along with the elemental analysis. Their prevention activity on the acute kidney injury in patients with acute cerebral hemorrhage is evaluated and the protentional mechanism is revealed. Firstly, the Nagl content in urine is measured. Secondly, the inflammatory response in glomerular epithelial cells is detected by real-time RT-PCR.

Two Mixed-ligand Coordination Polymers: Treatment Activity on Acute Oral Mucositis during Orthodontic Process by Reducing Inflammatory Response.

By modulating the metal centers to adjust the coordination surroundings of the products, two mixed-linker coordination polymers [Cu2(L)(biz)(OH)]·H2O (1) and [Zn(HL)(biz)] (2) (H3L = 5-(4-carboxybenzyloxy)isophthalic acid, biz = benzimidazole), have been produced under mild hydrothermal conditions. To develop new candidates for the acute oral mucositis during orthodontic process, the acute oral mucositis rat model was constructed and the enzyme linked immunosorbent assay (ELISA) was used to find out the release levels of inflammatory cytokines Tumor Necrosis Factor-α (TNF-α) and Interleukin-1β (IL-1β). Next, the activation of the AKT signaling pathway was estimated through judging the relative expression of the inflammatory genes in the oral mucosa cells via reverse transcription-polymerase chain reaction (RT-PCR). After compounds treatment, the expression level of the AKT signaling pathway was evaluated by a western blot. Finally, the quantity of the reactive oxygen species (ROS) in the oral mucosa cells was gauged with ROS detection kit. All the results in this research indicated the much more excellent treatment activity of compound 1 than 2 on the acute oral mucositis.