Micromilling mechanism studies are the fundamentals for high-quality micro components fabrications. Based on the finite element method (FEM), the simulation model for micromilling of the oxygen-free copper (OFC) was established in this paper. The influences of the key process parameters (feed engagement fz, axial depth of cut ap, radial depth of cut ae, and spindle speed n) on the milling forces were investigated. According to the simulation results, to achieve the minimum undeformed chip thickness, the critical feed engagement was identified to be 2.5 μm/z. when the axial depth of cut increased, the milling force was increasing linearly, but at the same time the milling force took an oscillator decreases due to the increasing of spindle speed. The overall trend of milling force under different radial depths of cut is upward. Therefore, the feed engagement should be greater than 2.5μm/z for micro milling of oxygen-free copper. Small radial depth of cut, small axial depth of cut, and appropriate spindle speed should be selected to obtain a high machining quality. Introduction As an excellent metal with extremely low oxygen content, high conductivity and high corrosion resistance, oxygen-free copper C10100 is widely used in the manufacturing of audio-visual equipment and communication components. With good ductility and no hydrogen embrittlement, it can also be processed into various precision micro parts. Compared with traditional cutting, high-speed micromilling is more suitable for machining micro-small parts. In order to obtain higher dimensional accuracy and better surface quality, it is necessary to study the milling parameters of OFC in the processing of precision parts. In the actual machining process, the changes of milling force caused by the changes of milling parameters can reflect the quality of the final machined parts more intuitively. Therefore, the adjustment of milling parameters can be guided by measuring the milling force in the milling process. In order to reveal the difference in mechanism between traditional cutting and micromilling, scholars have conducted a lot of studies. In the study of cutting poly-crystalling OFC with single crystalline diamond (SOD) micro-tools, X. Ding has proposed that the cutting strategy of reducing cross-feed can improve the cutting performance with using micro-tools. Constant cutting forces, burr size and an improved roughness of the machined surface have been obtained by employing this cutting strategy [1]. Niu has presented an innovative cutting force modeling concept by taking account of micro-cutting dynamics. Experimental cutting trial is conducted to validate the modeling approach and the cutting force model [2]. Qu has studied the impact of MQCL method on the machining results and mechanical properties of the component [3]. Yuan has proposed an innovative uncut chip thickness algorithm and developed the model for determining the instantaneous uncut chip thickness in micro end-milling processes [4]. D.DAS has studied the effect of stress parameters on ratcheting deformation stages of polycrystalline OFHC copper [5]. For the micromilling of pure copper, M. Rahman has studied the failure mechanism and factors which affect the micro end mill [6]. Liu has studied the relationship between size effect and burr in micromilling OFC and constructed a geometric model of exit burrs [7]. Liu has established SPH simulation model and carried out systematic research on formation mechanism of chip [8].For oxygen-free copper materials, Tian has established a constitutive model and carried out simulation analysis based on Abaqus [9]. Cheng has proposed 211