Minimum Redundancy Research Articles

DOA estimation technology based on array signal processing nested array

DOA estimation technology based on array signal processing nested array

Identification of Gene Expression in Different Stages of Breast Cancer with Machine Learning.

Determining the tumor origin in humans is vital in clinical applications of molecular diagnostics. Metastatic cancer is usually a very aggressive disease with limited diagnostic procedures, despite the fact that many protocols have been evaluated for their effectiveness in prognostication. Research has shown that dysregulation in miRNAs (a class of non-coding, regulatory RNAs) is remarkably involved in oncogenic conditions. This research paper aims to develop a machine learning model that processes an array of miRNAs in 1097 metastatic tissue samples from patients who suffered from various stages of breast cancer. The suggested machine learning model is fed with miRNA quantitative read count data taken from The Cancer Genome Atlas Data Repository. Two main feature-selection techniques have been used, mainly Neighborhood Component Analysis and Minimum Redundancy Maximum Relevance, to identify the most discriminant and relevant miRNAs for their up-regulated and down-regulated states. These miRNAs are then validated as biological identifiers for each of the four cancer stages in breast tumors. Both machine learning algorithms yield performance scores that are significantly higher than the traditional fold-change approach, particularly in earlier stages of cancer, with Neighborhood Component Analysis and Minimum Redundancy Maximum Relevance achieving accuracy scores of up to 0.983 and 0.931, respectively, compared to 0.920 for the FC method. This study underscores the potential of advanced feature-selection methods in enhancing the accuracy of cancer stage identification, paving the way for improved diagnostic and therapeutic strategies in oncology.

CT texture analysis of vertebrobasilar artery calcification to identify culprit plaques.

The aim of this study was to extract radiomic features from vertebrobasilar artery calcification (VBAC) on head computed tomography (CT) images and investigate its diagnostic performance to identify culprit lesions responsible for acute cerebral infarctions. Patients with intracranial atherosclerotic disease who underwent vessel wall MRI (VW-MRI) and head CT examinations from a single center were retrospectively assessed for VBAC visual and textural analyses. Each calcified plaque was classified by the likelihood of having caused an acute cerebral infarction identified on VW-MRI as culprit or non-culprit. A predefined set of texture features extracted from VBAC segmentation was assessed using the minimum redundancy and maximum relevance method. Five key features were selected to integrate as a radiomic model using logistic regression by the Aikaike Information Criteria. The diagnostic value of the radiomic model was calculated for discriminating culprit lesions over VBAC visual assessments. A total of 1,218 radiomic features were extracted from 39 culprit and 50 non-culprit plaques, respectively. In the VBAC visual assessment, culprit plaques demonstrated more observed presence of multiple calcifications, spotty calcification, and intimal predominant calcification than non-culprit lesions (all p < 0.05). In the VBAC texture analysis, 55 (4.5%) of all extracted features were significantly different between culprit and non-culprit plaques (all p < 0.05). The radiomic model incorporating 5 selected features outperformed multiple calcifications [AUC = 0.81 with 95% confidence interval (CI) of 0.72, 0.90 vs. AUC = 0.61 with 95% CI of 0.49, 0.73; p = 0.001], intimal predominant calcification (AUC = 0.67 with 95% CI of 0.58, 0.76; p = 0.04) and spotty calcification (AUC = 0.62 with 95% CI of 0.52, 0.72; p = 0.005) in the identification of culprit lesions. Culprit plaques in the vertebrobasilar artery exhibit distinct calcification radiomic features compared to non-culprit plaques. CT texture analysis of VBAC has potential value in identifying lesions responsible for acute cerebral infarctions, which may be helpful for stroke risk stratification in clinical practice.

Interpretable multiphasic CT-based radiomic analysis for preoperatively differentiating benign and malignant solid renal tumors: a multicenter study

BackgroundTo develop and compare machine learning models based on triphasic contrast-enhanced CT (CECT) for distinguishing between benign and malignant renal tumors.Materials and MethodsIn total, 427 patients were enrolled from two medical centers: Center 1 (serving as the training set) and Center 2 (serving as the external validation set). First, 1781 radiomic features were individually extracted from corticomedullary phase (CP), nephrographic phase (NP), and excretory phase (EP) CECT images, after which 10 features were selected by the minimum redundancy maximum relevance method. Second, random forest (RF) models were constructed from single-phase features (CP, NP, and EP) as well as from the combination of features from all three phases (TP). Third, the RF models were assessed in the training and external validation sets. Finally, the internal prediction mechanisms of the models were explained by the SHapley Additive exPlanations (SHAP) approach.ResultsA total of 266 patients with renal tumors from Center 1 and 161 patients from Center 2 were included. In the training set, the AUCs of the RF models constructed from the CP, NP, EP, and TP features were 0.886, 0.912, 0.930, and 0.944, respectively. In the external validation set, the models achieved AUCs of 0.860, 0.821, 0.921, and 0.908, respectively. The “original_shape_Flatness” feature played the most important role in the prediction outcome for the RF model based on EP features according to the SHAP method.ConclusionsThe four RF models efficiently differentiated benign from malignant solid renal tumors, with the EP feature-based RF model displaying the best performance.Graphical

Evaluation mechanism of sustainable development level for the cities in the Yangtze River Economic Belt under the dual-carbon policy.

Low carbon sustainable development (LCSD) has become an inevitable choice, for which China has put forward a "dual-carbon" policy. The purpose of this study is to capture the interaction between the environment and the economy in the context of this goal, thus evaluating LCSD level from a systematic perspective. This paper proposes a super slack based measurement (SBM) model with a non-equal weight structure to assess the LCSD level. Firstly, a maximum influence minimum redundancy (MIMR) index selection algorithm is designed to establish input and output index systems, which avoids redundancy indexes. Secondly, the objective function of the original super SBM employs an equal weight structure, which leads results inadequately reflect the research preferences. Therefore, the weights of indexes are introduced to form an improved super SBM. Finally, 40 cities along the Yangtze River Economic Belt (YREB) are selected for empirical analysis. Results show that (1) the LCSD level of YRBE decreases from downstream to upstream to midstream; (2) Jiangsu, Zhejiang, and Sichuan provinces have higher LCSD levels, while Hunan and Jiangxi provinces have lower levels; and (3) up to 2021, there are 32 effective cities and 8 ineffective cities. The research implies that balancing the economy-environment relationship is crucial for higher efficiency. The LCSD evaluation method not only reflects the coordination level between the economy and the environment, but also integrates the research preference into the results, providing decision support for the government to formulate carbon reduction policies and allocate resources.

Multi-institutional validation of a radiomics signature for identification of postoperative progression of soft tissue sarcoma

BackgroundTo develop a magnetic resonance imaging (MRI)-based radiomics signature for evaluating the risk of soft tissue sarcoma (STS) disease progression.MethodsWe retrospectively enrolled 335 patients with STS (training, validation, and The Cancer Imaging Archive sets, n = 168, n = 123, and n = 44, respectively) who underwent surgical resection. Regions of interest were manually delineated using two MRI sequences. Among 12 machine learning-predicted signatures, the best signature was selected, and its prediction score was inputted into Cox regression analysis to build the radiomics signature. A nomogram was created by combining the radiomics signature with a clinical model constructed using MRI and clinical features. Progression-free survival was analyzed in all patients. We assessed performance and clinical utility of the models with reference to the time-dependent receiver operating characteristic curve, area under the curve, concordance index, integrated Brier score, decision curve analysis.ResultsFor the combined features subset, the minimum redundancy maximum relevance-least absolute shrinkage and selection operator regression algorithm + decision tree classifier had the best prediction performance. The radiomics signature based on the optimal machine learning-predicted signature, and built using Cox regression analysis, had greater prognostic capability and lower error than the nomogram and clinical model (concordance index, 0.758 and 0.812; area under the curve, 0.724 and 0.757; integrated Brier score, 0.080 and 0.143, in the validation and The Cancer Imaging Archive sets, respectively). The optimal cutoff was − 0.03 and cumulative risk rates were calculated.Data conclusionTo assess the risk of STS progression, the radiomics signature may have better prognostic power than a nomogram/clinical model.

Improve the prediction in the digital Era: Causal feature selection with minimum redundancy

Effective decision-making in complex environments requires discerning the relevant from the irrelevant, a challenge that becomes pronounced with large multivariate time-series data. However, existing feature selection algorithms often suffer from complexity and a lack of interpretability, making it difficult for decision-makers to extract value, manage risks, and adhere to compliance regulations in a thoroughly explainable way. To address these challenges, we propose a novel causality-based feature selection technique that embeds an explainable unsupervised feature selection algorithm. We refer to our proposed method as Causal Feature Selection with Minimum Redundancy (CFSMR). Our method yields a minimum viable feature set without compromising model performance while ensuring interpretability. We conduct an experimental study to compare the proposed technique with conventional feature selection techniques. Our results demonstrate that our proposed method outperforms or performs on par with existing techniques, making it a promising approach for decision-makers seeking an effective and interpretable feature selection method.

Mid-to-long Term Wind Power Forecasting Based on ARIMA-BP Combined Model

Background: Increasing the accuracy of the output power forecasting for wind power is helpful to the improvement of the reliability of power dispatching. Objective: This study aimed to improve the forecasting accuracy of mid-to-long term wind power. Methods: A mid-to-long term wind power forecasting based on ARIMA-BP combined model was proposed. The Empirical Mode Decomposition (EMD) was used to decompose the historical wind power series and obtain the Intrinsic Mode Function (IMF) and residual components, thereby obtaining more regular components. Then, the optimum feature set was obtained based on the minimum Redundancy Maximum Relevance (mRAR) to improve the prediction accuracy for feature extraction. After that, the high-frequency components were predicted using the Back Propagation (BP) neural network model, while the low-frequency components were predicted using the Autoregressive Integrated Moving Average model (ARIMA). Finally, the predicted components obtained were superimposed to deduce the final mid- and long-term wind power prediction results. Results: An analysis was conducted according to the actual data from a typical wind farm. After comparison, it was found that, after empirical mode decomposition and feature extraction analysis, the error of the intelligent combination algorithm based on the ARIMA-BP combined model was smaller than that using only the BP neural network or only the ARIMA. Conclusion: By means of actual data analysis, the effectiveness of the method proposed by the study for mid- and long-term wind power prediction was verified.

Distinguishing diffuse large B-cell lymphoma from Hodgkin's lymphoma in children using an enhanced computed tomography radiomics approach.

Diffuse large B-cell lymphoma (DLBCL) and Hodgkin's lymphoma (HL) are two completely different pathologic subtypes of lymphoma with distinctly different clinical presentations and treatment options. Thus, accurately differentiating between the two subtypes has important clinical implications. This study aimed to construct a radiomics model capable of distinguishing between DLBCL and HL based on enhanced computed tomography (CT) for the non-invasive diagnosis of lymphoma subtypes. The clinical and imaging data of 16 patients confirmed to have DLBCL (33 lymphomas), and 50 patients confirmed to have HL (106 lymphomas) were retrospectively analyzed. The patients were completely randomized into a training set (n=107, DLBLC׃HL ratio: 23׃84) and a test set (n=32, DLBCL׃HL ratio: 10׃22). After multiple down-sampling, 2,264 radiomics features were automatically extracted by the application software. Feature selection was performed in the training set using Spearman's rank correlation coefficients, maximum correlation minimum redundancy, and the least absolute shrinkage and selection operator algorithm in that order. The features after selection were used to build radiomics models by logistic regression (LR) and quadratic discriminant analysis (QDA). We evaluated the model ability using receiver operating characteristic (ROC) curves and the DeLong test. Moreover, clinical indicators, such as gender, age, clinical stage, and lactate dehydrogenase (LDH), were collected and analyzed by univariate and multivariate LR analyses. The radiomics characteristics with clinical indicators that had independent influences on predicting the pathological subtypes were used to establish a comprehensive classification model. The analysis of the clinical data revealed that LDH can serve as a clinical indicator that has an independent influence on the prediction of HL and DLBCL. The results of the radiomics models were as follows: Radiomics_LR: area under the curve (AUC) =0.814 [95% confidence interval (CI): 0.628-0.999]; and Radiomics_QDA: AUC =0.841 (95% CI: 0.691-0.991). Following the inclusion of LDH as a clinical indicator in the analysis, the results of the comprehensive models were as follows: Radiomics + LDH_LR: AUC =0.768 (95% CI: 0.580-0.956); and Radiomics + LDH_QDA: AUC was 0.845 (95% CI: 0.695-0.996). The models based on radiomics and clinical features were able to effectively distinguish DLBCL from HL. The model with the best overall performance was the Radiomics_LR model.

Energy optimization for wireless sensor network using minimum redundancy maximum relevance feature selection and classification techniques

In wireless sensor networks (WSN), conserving energy is usually a basic issue, and several approaches are applied to optimize energy consumption. In this article, we adopt feature selection approaches by using minimum redundancy maximum relevance (MRMR) as a feature selection technique to minimize the number of sensors thereby conserving energy. MRMR ranks the sensors according to their significance. The selected features are then classified by different types of classifiers; SVM with linear kernel classifier, naïve Bayes classifier, and k-nearest neighbors classifier (KNN) to compare accuracy values. The simulation results illustrated an improvement in the lifetime extension factor of sensors and showed that the KNN classifier gives better results than the naïve Bayes and SVM classifier.

A data enhancement method based on generative adversarial network for small sample-size with soft sensor application

Soft sensor plays an important role in improving product quality; however, practical applications may often face with the problem of small sample size, which is challenging for developing data-driven models in terms of feature selection and good generalization. This paper proposes a data enhancement approach for small sample size data-driven problems based on generative adversarial networks integrated with maximum relevance minimum redundancy (MRMR). First, sample expansion is performed on the initial data by using a generative adversarial network. Second, irrelevant variables are eliminated by the MRMR and optimal features are obtained. Finally, neural networks-based soft sensor modeling is performed using the augmented dataset and the selected features. The proposed method is tested on a simulated penicillin case, an actual penicillin production case and an actual erythromycin production case. Experimental results show that the proposed method outperforms state-of-the-art existing methods, which verify the effectiveness and superiority of the proposed method.

ПОБУДОВА КОДІВ ХЕММІНГА В СКІНЧЕННИХ ПОЛЯХ ГАЛУА

Hamming codes and their modifications are key in numerous technological processes and systems, where minimizing errors is crucial for enhancing reliability and efficiency in data transmission or storage. They allow for the detection and automatic correction of single errors in each data block. Their relative simplicity to implement at the hardware and software levels, renders them useful in systems demanding high reliability. Moreover, they optimize transmission channel use due to their minimal redundancy. At work is the task of applying the properties of modular arithmetic to develop codes that can effectively correct errors in systems with higher bit rates than binary has been considered. Conducted research confirms that such codes can be tailored to meet specific data transmission system requirements, showcasing adaptability. The use of Hamming codes within finite Galois fields, leveraging modular arithmetic, further enhances correction capabilities and efficiency, streamlining implementation and computation processes. Error correction codes in finite Galois fields use the same principles applied in Hamming codes but take into account the mathematical properties of these fields for effective encoding, detection, and correction of errors.The proposed error correction method, through integration with modular arithmetic, opens possibilities for optimizing encoding and decoding processes, allowing for a higher level of data transmission reliability with minimal redundancy, which was previously limited by the properties of traditional codes. The proposed solution demonstrates the potential for using modular arithmetic for error correction but can provide a basis for further research in this area, opening new possibilities for improving information processing and transmission technologies.

APPLICATION OF THE PRINCIPLE OF MAXIMUM INFORMATIVENESS WITH MINIMAL EXCESS OF INFORMATION FOR SELECTING THE OPTIMAL NUMBER OF WATER QUALITY PARAMETERS

The quality of surface water plays a vital role in determining the sustainability of the ecological environment, the health of the population, and the socio-economic development of entire countries. Unfortunately, the rapid growth of the world's population together with the current climate change mainly deteriorates the state of surface water bodies. Thus, the use of effective methodologies capable of quickly and easily obtaining reliable information about the quality of surface water becomes fundamental for the effective use of water resources and implementation of mitigation measures and actions. Water pollution indices are one of the most widely used methods for providing a clear and complete picture of the state of river pollution, for the needs of rational water use and sustainable management of water resources. The selection of parameters is one of the most important and difficult stages, and the available statistical methods do not demonstrate great objectivity and accuracy in determining the real state of water quality. a new approach, based on the theory of entropy and known as the principle of maximum informativeness with minimum redundancy of information (MIMH), is proposed for determining the optimal subset of parameters describing the change in the quality level of a water body in space and time and, thus, determining the sources of pollution. The algorithm for the MIMN principle was implemented and applied to three rivers: the Southern Bug, the Dniester, and the Siverskyi Donets.

Radiomics for predicting MGMT status in cerebral glioblastoma: comparison of different MRI sequences.

Using radiomics to predict O6-methylguanine-DNA methyltransferase promoter methylation status in patients with newly diagnosed glioblastoma and compare the performances of different MRI sequences. Preoperative MRI scans from 215 patients were included in this retrospective study. After image preprocessing and feature extraction, two kinds of machine-learning models were established and compared for their performances. One kind was established using all MRI sequences (T1-weighted image, T2-weighted image, contrast enhancement, fluid-attenuated inversion recovery, DWI_b_high, DWI_b_low and apparent diffusion coefficient), and the other kind was based on single MRI sequence as listed above. For the machine-learning model based on all sequences, a total of seven radiomic features were selected with the Maximum Relevance and Minimum Redundancy algorithm. The predictive accuracy was 0.993 and 0.750 in the training and validation sets, respectively, and the area under curves were 1.000 and 0.754 in the two sets, respectively. For the machine-learning model based on single sequence, the numbers of selected features were 8, 10, 10, 13, 9, 7 and 6 for T1-weighted image, T2-weighted image, contrast enhancement, fluid-attenuated inversion recovery, DWI_b_high, DWI_b_low and apparent diffusion coefficient, respectively, with predictive accuracies of 0.797-1.000 and 0.583-0.694 in the training and validation sets, respectively, and the area under curves of 0.874-1.000 and 0.538-0.697 in the two sets, respectively. Specifically, T1-weighted image-based model performed best, while contrast enhancement-based model performed worst in the independent validation set. The machine-learning models based on seven different single MRI sequences performed differently in predicting O6-methylguanine-DNA methyltransferase status in glioblastoma, while the machine-learning model based on the combination of all sequences performed best.

Union is strength: the combination of radiomics features and 3D-deep learning in a sole model increases diagnostic accuracy in demented patients: a whole brain 18FDG PET-CT analysis.

FDG PET imaging plays a crucial role in the evaluation of demented patients by assessing regional cerebral glucose metabolism. In recent years, both radiomics and deep learning techniques have emerged as powerful tools for extracting valuable information from medical images. This article aims to provide a comparative analysis of radiomics features, 3D-deep learning convolutional neural network (CNN) and the fusion of them, in the evaluation of 18F-FDG PET whole brain images in patients with dementia and normal controls. 18F-FDG brain PET and clinical score were collected in 85 patients with dementia and 125 healthy controls (HC). Patients were assigned to various form of dementia on the basis of clinical evaluation, follow-up and voxels comparison with HC using a two-sample Student's t -test, to determine the regions of brain involved. Radiomics analysis was performed on the whole brain after normalization to an optimized template. After selection using the minimum redundancy maximum relevance method and Pearson's correlation coefficients, the features obtained were added to a neural network model to find the accuracy in classifying HC and demented patients. Forty subjects not included in the training were used to test the models. The results of the three models (radiomics, 3D-CNN, combined model) were compared with each other. Four radiomics features were selected. The sensitivity was 100% for the three models, but the specificity was higher with radiomics and combined one (100% vs. 85%). Moreover, the classification scores were significantly higher using the combined model in both normal and demented subjects. The combination of radiomics features and 3D-CNN in a single model, applied to the whole brain 18FDG PET study, increases the accuracy in demented patients.

Minimum Redundancy Maximum Relevancy-Based Multiview Generation for Time Series Sensor Data Classification and its Application

Minimum Redundancy Maximum Relevancy-Based Multiview Generation for Time Series Sensor Data Classification and its Application

Computed tomography-based radiomics diagnostic approach for differential diagnosis between early- and late-stage pancreatic ductal adenocarcinoma.

One of the primary reasons for the dismal survival rates in pancreatic ductal adenocarcinoma (PDAC) is that most patients are usually diagnosed at late stages. There is an urgent unmet clinical need to identify and develop diagnostic methods that could precisely detect PDAC at its earliest stages. To evaluate the potential value of radiomics analysis in the differentiation of early-stage PDAC from late-stage PDAC. A total of 71 patients with pathologically proved PDAC based on surgical resection who underwent contrast-enhanced computed tomography (CT) within 30 d prior to surgery were included in the study. Tumor staging was performed in accordance with the 8th edition of the American Joint Committee on Cancer staging system. Radiomics features were extracted from the region of interest (ROI) for each patient using Analysis Kit software. The most important and predictive radiomics features were selected using Mann-Whitney U test, univariate logistic regression analysis, and minimum redundancy maximum relevance (MRMR) method. Random forest (RF) method was used to construct the radiomics model, and 10-times leave group out cross-validation (LGOCV) method was used to validate the robustness and reproducibility of the model. A total of 792 radiomics features (396 from late arterial phase and 396 from portal venous phase) were extracted from the ROI for each patient using Analysis Kit software. Nine most important and predictive features were selected using Mann-Whitney U test, univariate logistic regression analysis, and MRMR method. RF method was used to construct the radiomics model with the nine most predictive radiomics features, which showed a high discriminative ability with 97.7% accuracy, 97.6% sensitivity, 97.8% specificity, 98.4% positive predictive value, and 96.8% negative predictive value. The radiomics model was proved to be robust and reproducible using 10-times LGOCV method with an average area under the curve of 0.75 by the average performance of the 10 newly built models. The radiomics model based on CT could serve as a promising non-invasive method in differential diagnosis between early and late stage PDAC.

Innovative approach towards early prediction of ovarian cancer: Machine learning- enabled XAI techniques

Globally, ovarian cancer affects women disproportionately, causing significant morbidity and mortality rates. The early diagnosis of ovarian cancer is necessary for enhancing patient health and survival rates. This research article explores the utilization of Machine Learning (ML) techniques alongside eXplainable Artificial Intelligence (XAI) methodologies to aid in the early detection of ovarian cancer. ML techniques have recently gained popularity in developing predictive models to detect early-stage ovarian cancer. These predictions are made using XAI in a transparent and understandable way for healthcare professionals and patients. The primary aim of this study is to evaluate the effectiveness of various ovarian cancer prediction methodologies. This includes assessing K Nearest Neighbors, Support Vector Machines, Decision trees, and ensemble learning techniques such as Max Voting, Boosting, Bagging, and Stacking. A dataset of 349 patients with known ovarian cancer status was collected from Kaggle. The dataset included a comprehensive range of clinical features such as age, family history, tumor markers, and imaging characteristics. Preprocessing techniques were applied to enhance input data, including feature scaling and dimensionality reduction. A Minimum Redundancy Maximum Relevance (MRMR) algorithm was used to select the features in the model. Our experimental results demonstrate that in Support Vector Machines, we found 85 % base model accuracy and 89 % accuracy after stacking several ensemble learning techniques. With the help of XAI, complex ML algorithms can be given more profound insights into their decision-making, improving their applicability. This paper aims to introduce the best practices for integrating ML and artificial intelligence in biomarker evaluation. Building and evaluating Shapley values-based classifiers and visualizing results were the focus of our investigation. The study contributes to the field of oncology and women's health by offering a promising approach to the early diagnosis of ovarian cancer.

Impacts of Feature Selection on Predicting Machine Failures by Machine Learning Algorithms

In the context of Industry 4.0, managing large amounts of data is essential to ensure informed decision-making in intelligent production environments. It enables, for example, predictive maintenance, which is essential for anticipating and identifying causes of failures in machines and equipment, optimizing processes, and promoting proactive management of human, financial, and material resources. However, generating accurate information for decision-making requires adopting suitable data preprocessing and analysis techniques. This study explores the identification of machine failures based on synthetic industrial data. Initially, we applied the feature selection techniques Principal Component Analysis (PCA), Minimum Redundancy Maximum Relevance (mRMR), Neighborhood Component Analysis (NCA), and Denoising Autoencoder (DAE) to the collected data and compared their results. In the sequence, a comparison among three widely known machine learning classifiers, namely Random Forest (RF), Support Vector Machine (SVM), and Multilayer Perceptron neural network (MLP), was conducted, with and without considering feature selection. The results showed that PCA and RF were superior to the other techniques, allowing the classification of failures with rates of 0.98, 0.97, and 0.98 for the accuracy, precision, and recall metrics, respectively. Thus, this work contributes by solving an industrial problem and detailing techniques to identify the most relevant variables and machine learning algorithms for predicting machine failures that negatively impact production planning. The findings provided by this study can assist industries in giving preference to employing sensors and collecting data that can contribute more effectively to machine failure predictions.

Chest CT radiomics is feasible in evaluating bone changes in chronic kidney diseases.

Non-invasive imaging methods are still lacking for evaluating bone changes in chronic kidney diseases (CKD). To investigate the feasibility of chest CT radiomics in evaluating bone changes caused by CKD. In total, 75 patients with stage 1 CKD (CKD1) and 75 with stage 5 CKD (CKD5) were assessed using the chest CT radiomics method. Radiomics features of bone were obtained using 3D Slicer software and were then compared between CKD1 and CKD5 cases. The methods of maximum correlation minimum redundancy (mRMR) and least absolute shrinkage and selection operator (LASSO) were used to establish a prediction model to determine CKD. The receiver operating characteristic (ROC) curve was used to determine the performance of the model. Cases of CKD1 and CKD5 differed in 40 radiomics features (P <0.05). Using the mRMR and LASSO methods, five features were finally selected to establish a predication model. The area under the receiver operating characteristic curve of the model in the determination of CKD1 and CKD5 was 0.903 and 0.854, respectively, for the training and validation cohorts. Chest CT radiomics is feasible in evaluating bone changes caused by CKD.