Introduction: Missing anterior teeth have a great impact on the psychological status of an individual due to the unesthetic appearance. These can be restored using removable prostheses, conventional bridges, resin-bonded prostheses, or implants. A resin-bonded fixed prosthesis is a minimally invasive treatment option in such cases to restore function and esthetics. Case Presentation: This case report describes the CAD-CAM zirconia Maryland bridge as a treatment modality for effective restoration of the missing maxillary central incisor in a 32-year-old female patient who reported the chief complaint of unesthetic appearance. The patient had a history of extraction due to trauma 6 months ago with normal overjet and overbite. Discussion: One of the types of resin-bonded prosthesis is a Maryland bridge which involves minimal tooth preparation with supragingival margins, thus maintaining periodontal health. Maryland bridges enhance dental esthetics with minimal loss of tooth structure. Conclusion: CAD-CAM fabricated all-ceramic resin-bonded prosthesis is an efficacious way of replacing missing anterior teeth, restoring function, providing excellent esthetics, and thus boosting patient’s confidence. Keywords: CAD-CAM zirconia, Maryland bridge, missing anterior tooth, resin-bonded fixed prosthesis, resin-bonded restoration.