Data are presented that reflect the indicators of mineral, pigment and lipid metabolism in domesticated elks with hoof damage in standard treatment, as well as in combination with thymogen.The study was performed on three groups of breeding stock 2 months before calving: control - healthy animals (n = 10) and two experimental animals (n = 3 in each): group 1 - with mild damage to the hooves (basic treatment regimen ), 2nd - with more severe and with additional inclusion in the treatment regimen of a five-day course of thymogen at a dose of 300 μg/head, intramuscularly.Blood for the study was taken before, on the 14th and 30th day of the experiment. Serum-ku was obtained by the conventional method.It was shown that a mild degree of damage to the hooves was accompanied by an increase in the level of calcium, sodium, magnesium, cholesterol, triglycerides, calcium-phosphorus ratio, a decrease in chlorine, phosphorus, potassium, total and direct bilirubin, osmolarity, and in more severe cases, an increase phosphorus, sodium, triglycerides against the background of a decrease in other components.The additional inclusion of thymogen in the scheme of therapeutic treatments in animals with a severe degree of damage contributed to a greater extent to the normalization of mineral metabolism, as evidenced by the indicators at the final stage of the experiments, which are closer to those of healthy animals than in the 1st experimental group. . The use of an immunocorrector minimized disturbances in pigment and lipid metabolism.