Clinical Application of Artificial Dermis and Autologous Skin in Repairing Skin and Soft Tissue Defects of Hands and Feet with Bone Exposure Injuries.

Weiying Chu,Songgen Peng,Guochao Deng,Weihai Song,Yanwen Lei,Chengke Li

doi:10.1155/2021/1202826

Abstract

Patients with skin and soft tissue defects are very common. Mild trauma often causes mild skin damage, while severe injuries are often accompanied by bone and tendon exposure, which brings great pain to patients. For the defect of skin and soft tissue, the traditional treatment methods are mostly medium or full-thickness skin or skin flap transplantation. These methods are effective in wound repair, but there are still many problems. In recent years, with the improvement of tissue engineering technology, the use of artificial skin to repair various skin wounds is gradually becoming clinical, and the key technology of skin tissue engineering lies in the development of dermal substitutes. The appearance of artificial dermis not only solves the shortage of autologous skin source but also makes the operation simple and easy. The purpose of this study was to investigate the clinical effect of artificial dermis combined with autologous skin grafts in repairing hand and foot skin and soft tissue defects with bone exposure. The results show that the use of artificial dermis combined with autogenous blade thick skin to treat patients with hand and foot soft tissue injury with bone exposure has a good clinical effect, and the skin is alive and has fewer complications, which is worthy of promotion.

Highlights

With the continuous development of modern society and the acceleration of industrialization and mechanization, the probability of traffic accident injury, severe burn, and high falling injury in daily life is increased, and the number of patients with limb skin and soft tissue defects is gradually increased
Mild trauma often causes mild skin damage, and severe cases are often accompanied by bone and tendon exposure, bringing great pain to patients [1, 2]. erefore, how to effectively clean up the wound to control infection and repair skin and soft tissue defects is a major clinical problem
The silica gel membrane is removed and the autologous thin skin layer is implanted, which can achieve good repair effect [9, 10]. e appearance of artificial dermis solves the shortage of autologous skin source and makes the operation simple and easy. e purpose of this study was to investigate the clinical effect of artificial dermis combined with autologous skin grafts in repairing hand and foot skin and soft tissue defects with bone exposure. e specific report is as follows

Summary

Introduction

With the continuous development of modern society and the acceleration of industrialization and mechanization, the probability of traffic accident injury, severe burn, and high falling injury in daily life is increased, and the number of patients with limb skin and soft tissue defects is gradually increased. Erefore, how to effectively clean up the wound to control infection and repair skin and soft tissue defects is a major clinical problem.

Results

Conclusion