Population Migration Research Articles

Acculturation and self-management abilities of well-being among older Moroccans in the Netherlands

Abstract Background Migration involves a variety of stressors. Their accumulation over time may negatively impact migrants’ well-being. The extent that older migrants can integrate into a host society may determine their readiness to adopt behaviors such as self-management of well-being. Research regarding this relation among older Moroccans, one of the largest migrant groups in the Netherlands, has not been examined. This study aimed to investigate the relationship between acculturation and self-management abilities of well-being among older Moroccans and to examine differences in subgroups. Methods This cross-sectional study included 290 older Moroccans (≥ 65) living in Rotterdam, the Netherlands. Linear regression was applied to explore associations between acculturation (attachment to Moroccan and Dutch cultures) and self-management abilities of well-being. Independent samples t-tests were used to test differences between subgroups. Results Older Moroccans who received low education were found to be less attached to the Dutch culture [3.24 (0.72) vs. 3.54 (0.73); p = 0.016]. They were also poorer self-managers of their well-being [2.60 (0.59) vs. 2.86 (0.58); p = 0.012], along with those with multi-morbidity [2.55 (0.60) vs. 2.77 (0.54); p = 0.006] and those lacking comprehension of Dutch [2.46 (0.56) vs. 2.69 (0.59); p = 0.011]. Self-management abilities of well-being had a negative association with multi-morbidity (β = −0.18, p = 0.007) and lack of Dutch comprehension (β = −0.16, p = 0.031), and a positive association with attachment to Moroccan (β = 0.17, p = 0.012) and Dutch (β = 0.18, p = 0.010) cultures. Conclusions Findings indicate that attachment to Moroccan and Dutch cultures is beneficial for older Moroccans’ self-management of well-being. Efforts need to support older migrants’ integration for them to adequately function and feel at home. Interventions promoting integration and self-management need to consider the characteristics of older migrant populations Key messages • Attachment to origin and host cultures benefits older migrants’ self-management of well-being. The cultural context of older migrants needs to be considered when promoting values of self-management. • Differences in acculturation and self-management of well-being existed between older migrant subgroups. Interventions promoting these values should account for the diversity that exists among migrants.

Molecular transmission clusters in newly HIV-1 diagnosed migrants in Portugal from 2014 to 2019

Abstract Background Portugal has an important HIV burden with a total of 804 diagnosed cases in 2022. Migrants remain a significant source of HIV infections, with 45% of newly reported cases. We aimed to evaluate the characteristics of HIV-1 molecular transmission clusters (MTCs) among migrants followed in Portugal, diagnosed between 2014 and 2019. Methods 265 migrants, newly HIV-1 diagnosed were included in the BESTHOPE project with clinical, socio-behavioral and genomic data. Pol nucleotide-based phylogenetic analyses were used to infer HIV-1 MTC. Those were constructed using ClusterPickerGUI_1.2.3 considering SH-aLRT higher than 90 of branch support and a pairwise genetic distance of ≤ 4.5. Logistic regression analyses were used to examine the relationship between the sociodemographic and clinical data associated with HIV-1 clustering. Results 66.8% of the migrants included in the study were males with a median age at diagnosis of 36.0 years old (IQR:29-45). Most migrants were from African countries (50.6%) followed by Brazil (39.6%). Sixty-eight (33%) of the migrants were included in clusters. Being in cluster was significantly associated with region of origin, with individuals from South America more likely to be in cluster (OR = 14.85, 95%CI:1.52-144.79), compared to individuals from Africa; with transmission route, with men who have sex with men (MSM) more likely to be in cluster (OR = 23.52, 95%CI:2.35-235.10), compared to the heterosexuals and with subtype, with subtypes B less likely to be in cluster (OR = 0,017, 95%CI:0,001-0,254) compared with subtype non-B. Conclusions Migrants HIV transmission clusters in Portugal are associated with specific health determinants, such as region of origin, transmission route and subtype. Targeted prevention health strategies are needed to mitigate transmission of HIV within this population. Funded by FCT to GHTM - UID/04413/2020 and LA-REAL - LA/P/0117/2020; BESTHOPE (HIVERA:249697); and MARVEL (PTDC/SAU-PUB/4018/2021). Key messages • HIV transmission clusters in migrant are associated with their region of origin, transmission route and subtype. • Targeted prevention health strategies are needed for the migrant population.

Preparing for outbreaks of vaccine preventable diseases: why are prisons invisible?

Abstract From 1 March 2023 to 29 February 2024, 30 EU/EEA Member States reported a total of 5 770 cases of measles, 4 864 (84.3%) of which were laboratory-confirmed. Th7e highest number of cases were reported by Romania- at the time of writing, 11,397 confirmed cases, including 12 deaths from 1 January 2023 to 7 April 2024. Measles is a highly infectious disease. The best mitigation is vaccination which is highly effective. Outbreaks in many countries have been driven by decreases in vaccine coverage with a two-dose measles-containing vaccine (MCV), especially evident since the COVID-19 pandemic. In many countries, vulnerable migrant populations, ethnic groups and communities experiencing social deprivation have been over-represented in cases and under-covered by vaccine programmes. We know that prisons contain such populations. Historic seroprevalence studies of prison populations, which themselves are scant, show that prison populations are under-vaccinated. Prisons are a setting that can cause disease amplification. Given these facts, it is perhaps surprising that many countries in Europe cannot provide specific surveillance data on either cases in prisons or vaccine coverage specifically in prison populations. Further, that prisons are not often cited as specific settings for vaccine catch-up programmes in national or regional programmes. This is despite evidence of measles cases and outbreaks historically and currently in several European countries. In the presentation we will ask why this ‘blind spot’ in national and international disease surveillance continues and what Member States could and should do to prevent the risk of mass outbreaks of measles in prisons, causing pressures on justice and health systems and risking wider community outbreaks. Finally, we will reflect on how this experience should alert us to the risk of other infectious diseases going undetected, unprevented, and under-studies in prisons, threatening our collective health security.

Identifying the zero-dose and under-immunized children in Bangladesh: Approaches and experiences.

This paper presents and elaborates on empirical methods and approaches used to identify Zero-Dose (ZD) and Under-immunized (UI) children as well as the communities that these children reside in within Bangladesh. This paper also describes demand- and supply side-barriers that lead to children being ZD and UI in the country. Time period for the study was December 2022-May 2023. The study methodology encompassed secondary data analysis using data from national surveys, primary data collection and analysis via a lot quality assurance sampling (LQAS) survey and also, qualitative data collection and analysis. Study population included caregivers of children aged 4.5 months (4 months 15 days) to 23 months for the LQAS survey. The qualitative component included policymakers, program managers and service providers working in immunization as well as mothers in the selected study areas who had a living child aged less than 2 years as the study population. Our data analysis confirms existence of ZD and UI children in areas which were categorized into haor (wetlands), hilly, char (sandy/silty land surrounded by water), coastal, plain land and urban slums. Determinant analysis showed that the mother's level of education, antenatal visits made, and access to media were significantly associated with children being ZD or UI. Reproductive autonomy emerged as a key factor that had prominent impact on a child being ZD. The qualitative analysis indicated the importance of population migration, health workforce shortages and lack of access to transportation as prominent barriers to immunization. Notably, the methods and approaches used in this study are both effective and easily replicable to identify ZD and UI children. The drivers of ZD and UI along with the barriers to immunization provide potential areas for intervention by policy-makers and can apprise about interventions to be tested in future implementation research.

Residential mobility and social capital: Regional analysis in Finland

AbstractMultiple factors can influence the rates of residential mobility flows between different regions of a country. Studies have often focused on demographic and economic factors, but social conditions may be relevant as well. We examined whether different indicators of social capital (i.e., social support, loneliness, social trust, community participation, cultural activities, and meeting other people) were associated with population migration rates across 299 municipalities of Finland. Data for the social characteristics were derived from the Regional Health and Wellbeing study (n = 100,750 respondents) aggregated to the level of municipalities using multilevel regression with post‐stratification (median number of participants was 115 individuals per municipality, range from 5 to 10,616). Residential mobility rates were derived from census data. Municipalities with higher levels of social support, higher social trust, more cultural activities, and more frequent social contacts had higher net migration rates, that is, more people moving in than out of the municipality. Social support, cultural activities, and community participation were associated with higher in‐migration. Social trust and frequency of meeting people were associated with lower out‐migration. The findings provide empirical support for the hypothesis that regions with stronger social capital are more attractive destinations for within‐country residential mobility.

Amenities and housing market dynamics: Implications for population change, urban attractiveness, innovation, and productivity

This introductory essay aims to provide a comprehensive overview of a collection of 17 articles, previously published in the Urban Studies journal, now consolidated as a ‘virtual special issue’. The articles contribute to numerous strands of what has, over the decades, become an extremely voluminous literature concerning the interplay between population change and productivity within cities. It is important to acknowledge that the volume of this literature makes it effectively impossible to summarise effectively in a single essay. This article instead presents a contextual overview, a glimpse into the various thematic strands arising from the literature, and an introduction to each of the selected virtual special issue articles themselves. It briefly highlights the unique contributions of these articles to the overarching objective of the Urban Studies journal, which is to advance our understanding of the urban condition. Yet, it is also worth noting that the literature does not neatly segregate into distinct strands. Indeed, several contributing authors within the virtual special issue rightly emphasise the significant interdependencies between population change, migration patterns, specialisation, firm location, urban and natural amenities, agglomeration economies, and productivity. This essay attempts to progress logically from one strand to another, with a specific focus on labour and housing markets, as well as transportation costs or systems, as mediators of these complex relationships. Finally, the essay concludes by bringing attention to several strands of future inquiry that might prove fruitful and would be of interest to the readership of this journal.

Migration and Economic Development: The Role of Migrant Flows in Shaping Turkey’s Emerging Economy and Uncovering Hidden Conflicts and Challenges

This research examines the economic impact of migration on Turkey's emerging economy, with a particular focus on the contributions of migrant remittances, labor market dynamics, and the socio-political challenges associated with large-scale migrant flows. By employing econometric models and field research, the study explores the relationship between remittance inflows and key economic indicators such as GDP growth, employment rates, and poverty reduction. Additionally, the research uncovers hidden conflicts and social tensions that arise from migration, including labor market inequalities and integration challenges faced by both migrants and Turkish workers. The project evaluates government policies, such as the EU-Turkey refugee agreement, and their effects on economic development and social stability. Field research in migrant-receiving communities reveals the complexities of labor competition and the social dynamics created by migrant dependency in sectors such as agriculture and construction. Findings highlight the need for inclusive migration policies that balance the economic benefits of remittances with the social integration challenges faced by migrant populations. This study also advocates for stronger labor protections and regulatory reforms to mitigate tensions and reduce exploitation in low-wage sectors. The research contributes to the broader understanding of migration’s role in shaping Turkey’s economy and provides insights for policymakers seeking to address both the economic and social dimensions of migration.

Temporal and spatial variation in reproductive benefits in a partial migrant.

In partial migrant systems, where residents and migrants coexist within a population, residents are commonly predicted to gain a reproductive advantage over migrants through priority access to high-quality territories and an earlier breeding start. Annual variation in reproductive benefits has been suggested to be important for the coexistence of both strategies in a population, as differences in wintering conditions experienced by the two strategies may result in a periodic reproductive advantage for migrants. However, the importance of spatial environmental variation for reproductive output in partially migrant populations remains largely unexplored. We investigated variation in the reproductive output of migrants and residents in a population of Swiss red kites (Milvus milvus) both temporally, across and within years, and spatially, along an elevational gradient. We gathered 4 years of reproductive data combined with 183 GPS-derived full annual cycles from individuals breeding in the Swiss Alpine foothills. At low, but not high, elevations, residents produced more fledglings than migrants. We also found evidence for annual variation in the reproductive advantage of the two strategies. Furthermore, while reproductive output did decline with a later breeding start, there was no difference in the start of breeding between the two migration strategies. The results of this study suggest that differences in reproductive output between migrants and residents in partial migrant populations can vary both due to the use of spatially distinct overwintering grounds and because the strategies are differently affected by spatial variables in the breeding area, such as elevation. The study emphasizes that spatial and temporal variation in reproductive benefits must be considered when predicting how migratory species will respond to future environmental change.

All-cause and cause-specific mortality among older migrant and non-migrant adults in Finland: a register study on all deaths, 2002-2020.

Migrant mortality advantage is established in various studies, but there is a lack of evidence on migrant mortality trends in old age. Previous studies have primarily concentrated on all-cause mortality, and few include older age groups. Discussions about the migrant mortality advantage continue due to concerns about data availability and accuracy. Additionally, the mechanisms explaining the migrant mortality advantage remain unclear. This study examines all-cause and cause-specific mortality among older migrant and nonmigrant adults aged 70 and above using Finnish Cause of Death register data (2002-20) and the corresponding risk population. We investigate differences in overall and cause-specific mortality between migrant and Finnish-born population and by geographical region of origin. We calculated direct age-standardized mortality rates and age group-specific death rates followed by Poisson regression to study relative mortality differences. Age at death, sex, income, region of residence, and year of death were controlled for in the regression analysis. We found evidence of migrant mortality advantage across various causes of death, but there was variation by regions of origin groups and sex. Notably, women exhibit the strongest advantage in respiratory and digestive system diseases, while men demonstrated pronounced advantages in external causes and respiratory diseases. Our study challenges the notion of a general diminishing healthy migrant effect in old age. Our findings emphasize the need for nuanced investigations into socioeconomic factors and tailored interventions for older migrants.

Reconstructing a georeferenced inventory of flooding hazards in Raoping, Guangdong province, China, from 1492 to 1985

ABSTRACT In ancient times, there is a scarcity of instrumental water flow data, which challenges the hydrological science community to understand the evolution of flood risk under the changing climate over the centennial scale. Based on the historical records of flood events, the first spatio-temporal database of flood risk occurrence was established in Raoping county, Guangdong, China from 1492 to 1985 (a 494-year period), with intensive human interpretation and local investigation. Specifically, the spatially explicit flood events of the river network were provided for each flood episode. A detailed analysis of the database shows a high frequency of flood risk in summer and early autumn. Specifically, a significant (p < 0.05) increase has been found in flood risks since 1960. However, flooding decreased significantly in recent decades due to meteorological and hydrological factors, as well as the population density and migration during the 500-year period. A spatial clustering of flood events in the northern and southern parts is also confirmed, which shows an impact of population dynamics on a centennial scale. Such methods can be a reference for establishing China's flooding database for ancient periods, promoting a better understanding of natural hazards and associated human behaviors under the context of long-term climate change.

Agent-Based Geosimulation of Yayoi Period Population Dynamics in Kyushu, Japan

Current scholarship in Japanese archaeology recognizes the people and culture of the Yayoi period as being descended from both continental migrants (Toraijin) and the native inhabitants (Jomon people). However, the number of migrants that came to Japan and the degree to which they were directly responsible for the development of Yayoi culture is a topic of debate. Using northern Kyushu as a case study, the author employs an agent-based simulation based on geospatial data to model the spread of population, rice agriculture, and continental genetics during the Early Yayoi period. Multiple simulations are performed with varying parameters related to migrant population size, marriage customs, and the ratio of men to women amongst migrants to test their effect on the demographics of the Yayoi period. Simulation results were compared to population estimates and the distribution of mitochondrial DNA in order to determine their validity. Experiment 1 showed that the average number of continental migrants was likely in the order of magnitude of 10s of people per year (approx. 40 to 50) during the first 500 years of the Yayoi period. Experiment 2 demonstrated that polygyny can lead to increased population growth and aids in the spread of continental genetics, but without more rigorous evaluation criteria it is difficult to conclude whether it was practiced during the period. The methods used in this study demonstrate how agent-based simulations can model realistically sized populations moving through geographic space by basing simulation inputs on geospatial data and population estimates.

Identification and Analysis of Peak Population Migration Patterns in the Beijing-Tianjin-Hebei Region Based on Complex Network Theory

Abstract. As a vital economic and population agglomeration area in China, the Beijing-Tianjin-Hebei region has attracted considerable attention regarding population migration issues. Population migration not only directly affects the population size and structure of cities within the region but also has profound implications for economic development, social stability, and urban planning. This study extends the analysis to the "Spring Festival Travel Rush" period, using population migration data from January to March in the years 2020 to 2022 as the basis. By employing complex network theory and relevant statistical indicators, the study explores the peak period population migration patterns and their variations in the Beijing-Tianjin-Hebei region. The research firstly identifies significant changes in population migration patterns in the Beijing-Tianjin-Hebei region around 2021 and analyzes the changing patterns. Secondly, network statistical indicators indicate hierarchical population migration patterns based on city tiers. Furthermore, cities with unique migration patterns are identified. Finally, based on an in-depth exploration of population migration patterns and their variations in the Beijing-Tianjin-Hebei region, the study provides suggestions and prospects for future urban planning and development, offering important references for addressing the challenges posed by population migration in the region.

Heat impacts on an aging society: a spatio-temporal analysis of heatstroke deaths in Japan

Abstract Climate change, especially through heatwaves, significantly affects human health and is a growing global concern. Concurrently, population aging is occurring worldwide, with many countries experiencing an increase in their elderly populations. As the elderly are particularly susceptible to extreme temperatures and unevenly distributed due to internal migration of younger populations, a spatio-temporal analysis integrating temperature changes and demographic data is essential. This study focuses on Japan, a super-aged society where over 25% of the total population is 65 years or older. We examined the effects of climate and the proportion of the elderly population on heatstroke deaths through spatio-temporal analysis within a Bayesian framework. We estimated the annual relative risk of heatstroke-related deaths at the prefecture level from 2008 to 2019. The results indicate a strong spatial autocorrelation in heatstroke deaths across Japan. The spatio-temporal interaction model was the best-performing, showing that regional and temporal variations significantly impact heatstroke mortality. In this model, a one-degree increase in temperature anomaly was linked to a 0.35 (95% CI 0.25 to 0.46) times higher odds of heatstroke deaths, while a 1% increase in the population aged 65 years or older was associated with 4.85 (95% CI 0.92 to 8.65) times higher odds. We found that not only metropolitan areas but also rural areas, such as the Tohoku and Shikoku regions, face a high risk of heatstroke, emphasizing the need to address the challenges in rural communities. Our study highlights the necessity of integrating temperature changes and demographic data in a spatio-temporal context for heatstroke risk assessment. It demonstrates the profound effects of temperature anomalies and the proportion of the elderly population on heatstroke mortality. This research framework could be applicable to other countries experiencing aging and heatwave issues, aiding in the development of targeted public health interventions.

Strength of seasonality and type of migratory cue determine the fitness consequences of changing phenology for migratory animals

Phenological mismatch has been highlighted as a reason why climate change is causing declines of migratory populations. The likelihood of declines due to phenological mismatch might depend on what cues trigger migration. Migrants that use environmental cues (e.g. temperature, resource availability) to trigger migration are often considered to be less vulnerable than migrants that use temporal information (e.g. photoperiod). We developed a proof‐of‐concept model that demonstrates that which cue type performs better in the context of phenological change can depend on differences in seasonal amplitude between the habitats used by a migrant. Environmental cues perform better than temporal cues when the habitat that undergoes a phenological change has a larger seasonal amplitude. This result aligns with observations that populations of short‐distance migrants that use environmental cues are less likely to decline as a consequence of phenological mismatch than long‐distance avian migrants that use temporal cues. Temporal cues perform better than environmental cues when the habitat that undergoes a phenological change has a smaller seasonal amplitude. This result may correspond to empirical scenarios where the more seasonal habitat is associated with variation in precipitation patterns or human actions that are not changing in phenology. In addition to these results, we offer distinctions that will help clarify future work on phenological mismatch. First, we highlight the difference between the cue accuracy (difference between the timing of migration using the cue and optimal migration timing) and the cue efficacy (the difference between the fitness using the cue and the fitness using optimal migration). Second, we recommend considering both how the benefits available from migrating and the benefits that are captured by migrants change with phenological change.

Prevalence and epidemic pattern of ecdemic multidrug-resistant tuberculosis during 2012–2022 in Hangzhou, China: implication for public health strategies

BackgroundTo assess the prevalence and epidemic pattern of multidrug-resistant tuberculosis in Hangzhou City, Zhejiang Province, China during 2012–2022.MethodsAll the tuberculosis cases undergoing drug susceptibility testing during 2012–2022 were included in this study. De-identified information was extracted from the electronic database Tuberculosis Information Management System for analysis of drug resistance prevalence in Hangzhou and ecdemic multidrug-resistant tuberculosis which originated from other regions. Chi-square tests were used to compare drug resistance rates between different groups, while Chi-square tests for trend were used to evaluate the change of drug resistance rates over the years of 2012–2022. The sources and destinations of ecdemic multidrug-resistant tuberculosis were illustrated using a Sankey diagram.ResultsOf 21,127 cases included in this study, 1119 (5.3%) were multidrug-resistant tuberculosis. A significant decline in multidrug-resistant tuberculosis rates was observed during 2012–2022. There was a significant difference in multidrug-resistant tuberculosis rates among immigrant population and local residents in Hangzhou City. Of 1119 multidrug-resistant tuberculosis cases, 515(46%) were ecdemic multidrug-resistant tuberculosis cases, of which 277(53.8%) were from other parts of Zhejiang Province and 238(46.2%) were from other provinces in China. Anhui, Jiangxi and Sichuan were among top three provinces which were the source of ecdemic multidrug-resistant tuberculosis cases. Three districts including Xiaoshan, Shangcheng and Linping districts had the most cases in Hangzhou. The proportion of ecdemic multidrug-resistant tuberculosis cases in Binjiang, Xiaoshan, Qiantang and Linping districtalso exceeded 30% of total cases.ConclusionsMultidrug-resistant tuberculosis prevalence has been declining in Hangzhou. Migrant population contributed to a significant potion of cases in Hangzhou. Interventions should be tailed to local and migrant residents.

To what extent did mortality from COVID-19 in England and Wales differ for migrants compared to non-migrants in 2020 and 2021? A descriptive, observational study.

Seventeen percent of people living in the UK are migrants. In high-income countries, migrants have been shown to have better all-cause mortality but worse mortality for some specific causes such as infectious diseases. This observational study aims to quantify the extent to which mortality from coronavirus disease 2019 (COVID-19) differed between migrants and non-migrants for the population of England and Wales, 2020-2021. We use Official National Statistics data to compare mortality from COVID-19 in 2020 and 2021 by country/region of birth, expressed as the standardized mortality ratio with those born in England and Wales as the reference population. Migrants from 17 of 19 countries/regions examined had higher mortality from COVID-19 than non-migrants. The highest mortality was those born in Bangladesh (females SMR = 3.39, 95% CIs 3.09-3.71; males 4.41, 95% CIs 4.09-4.75); Pakistan (females 2.73, 95% CIs 2.59-2.89; males 3.02, 95% CIs 2.89-3.14); and the Caribbean (females 2.03, 95% CIs 1.87-2.20; males 2.48, 95% CIs 2.37-2.60). Migrants born in Antarctica and Oceania (females 0.54, 95% CI 0.42-0.40; males 0.71, 95% CI 0.51-0.88), and North and Central America (females 0.95, 95% CI 0.80-1.11; males 0.85, 95% CI 0.72-0.99) had lower mortality than non-migrants. Most migrant populations had higher mortality from COVID-19 than non-migrants in England and Wales. Policy-makers must work to integrate migration status into routine data collection to inform future research and understand the causes of the inequalities seen.

Potential cardiac-derived exosomal miRNAs involved in cardiac healing and remodeling after myocardial ischemia–reperfusion injury

Migratory cells exist in the heart, such as immune cells, fibroblasts, endothelial cells, etc. During myocardium injury, such as ischemia–reperfusion (MIRI), cells migrate to the site of injury to perform repair functions. However, excessive aggregation of these cells may exacerbate damage to the structure and function of the heart, such as acute myocarditis and myocardial fibrosis. Myocardial injury releases exosomes, which are a type of vesicle with signal transduction function and the miRNA carried by exosomes can control cell migration function. Therefore, regulating this migratory cell population through cardiac-derived exosomal miRNA is crucial for protecting and maintaining cardiac function. Through whole transcriptome RNA sequencing, exosomal miRNA sequencing and single-cell dataset analysis, we (1) determined the potential molecular regulatory role of the lncRNA‒miRNA‒mRNA axis in MIRI, (2) screened four important exosomal miRNAs that could be released by cardiac tissue, and (3) screened seven genes related to cell locomotion that are regulated by four miRNAs, among which Tradd and Ephb6 may be specific for promoting migration of different cells of myocardial tissue in myocardial infarct. We generated a core miRNA‒mRNA network based on the functions of the target genes, which may be not only a target for cardiac repair but also a potential diagnostic marker for interactions between the heart and other tissues or organs. In conclusion, we elucidated the potential mechanism of MIRI in cardiac remodeling from the perspective of cell migration, and inhibition of cellular overmigration based on this network may provide new therapeutic targets for MIRI and to prevent MIRI from developing into other diseases.

The impact of social determinants of health on international migrants’ health outcomes: a bibliometric analysis

Purpose The aim of this study is to conduct an in-depth exploration of the research landscape concerning the impact of social determinants of health (SDH) on the health outcomes of international migrants. Design/methodology/approach Leveraging the extensive Scopus database, this study retrieved a total of 2,255 articles spanning the years 1993–2023. The framework for analysis used the SDH categories outlined by the World Health Organization. Findings The research landscape exhibited an apparent increase in the number of publications, but not a net increase in the research productivity. The USA emerged as the leading contributor to research output, with the Journal of Immigrant and Minority Health emerging as the most prolific publication venue, and the University of Toronto ranking as the most prolific institution. The SDH category that received the highest number of publications was the “community and social context”. Migrants from different regions in Asia (East, Central and South Asia) and those from Latin America and the Caribbean region appeared to be the most commonly researched. Highly cited articles predominantly delved into mental health outcomes arising from discrimination and migration policies. Research limitations/implications The findings proffer valuable insights for shaping future research endeavors, accentuating the imperative for diversified studies encompassing underrepresented domains, broader health outcomes and the inclusion of migrant populations from different world regions in investigative pursuits. Originality/value This study delivers a comprehensive analysis of the research landscape, unveiling critical trends in the realm of SDH and migrant health outcomes.

Epidemic Situation in Osh, Kyrgyz Republic on Infections Controlled by Specific Prevention Means and Analysis of Population Awareness on Measles Infection

The article reflects a long-term (2009-2023) retrospective epidemiological analysis of measles incidence among the population in Osh, characterized by a periodic increase in incidence every two to three years and a decline after the adopted response measures to outbreaks, such as additional mass immunization of vulnerable groups of the population. However, the increase in measles incidence that began in 2018 continued for three years (2018-2020). Also, the increase in measles incidence, which began in the spring-summer period in 2023, despite the organization of preventive and anti-epidemic measures, continues in 2024, starting from the winter-spring period. This study revealed low vaccination coverage of children in the period from 2019 to 2023 at the level of 85.0-95.0%, which is associated with various reasons (underage, medical exemptions, parental refusal to vaccinate, population migration and unknown vaccination status, etc.).

Cell type and regulatory analysis in amphioxus illuminates evolutionary origin of the vertebrate head

To shed light on the enigmatic origin of the vertebrate head, our study employs an integrated approach that combines single-cell transcriptomics, perturbations in signaling pathways, and cis-regulatory analysis in amphioxus. As a representative of a basal lineage within the chordate phylum, amphioxus retains many characteristics thought to have been present in the common chordate ancestor. Through cell type characterization, we identify the presence of prechordal plate-like, pre-migratory, and migratory neural crest-like cell populations in the developing amphioxus embryo. Functional analysis establishes conserved roles of the Nodal and Hedgehog signaling pathways in prechordal plate-like populations, and of the Wnt signaling pathway in neural crest-like populations’ development. Furthermore, our trans-species transgenic experiments highlight similarities in the regulatory environments that drive neural crest-like and prechordal plate-like developmental programs in both vertebrates and amphioxus. Our findings provide evidence that the key features of vertebrate head development can be traced back to the common ancestor of all chordates.